LOCUS       sequence-29445-e         708 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 708)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 708)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PRKAG3
FEATURES             Location/Qualifiers
     source          1..708
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    10..109
                     /gene="mutant version of attL"
                     /label=attL1
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 agctcgggcc caataatgat tttattttga ctgatagtga cctgttcgtt gcaacaaatt
       61 gatgagcaat gcttttttat aatgccaact ttgtacaaaa aagttggcac catggagccc
      121 gggctggagc acgcactgcg caggacccct tcctggagca gccttggggg ttctgagcat
      181 caagagatga gcttcctaga gcaagaaaac agcagctcat ggccatcacc agctgtgacc
      241 agcagctcag aaagaatccg tgggaaacgg agggccaaag ccttgagatg gacaaggcag
      301 aagtcggtgg aggaagggga gccaccaggt cagggggaag gtccccggtc caggccagct
      361 gctgagtcca ccgggctgga ggccacattc cccaagacca cacccttggc tcaagctgat
      421 cctgccgggg tgggcactcc accaacaggg tgggactgcc tcccctctga ctgtacagcc
      481 tcagctgcag gctccagcac agatgatgtg gagctggcca cggagttccc agccacagag
      541 gcctgggagt gtgagctaga aggcctgctg gaagagaggc ctgccctgtg cctgtccccg
      601 caggccccat ttcccaagct gggctgggat gacgaactgc ggaaacccgg cgcccagatc
      661 tacatgcgct tcatgcagga gcacacctgc tacgatgcca tggcaact
//
