LOCUS       sequence-29489-e         727 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 727)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 727)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-MAPK12
FEATURES             Location/Qualifiers
     source          1..727
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    8..107
                     /gene="mutant version of attL"
                     /label=attL1
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 ctcgggccca ataatgattt tattttgact gatagtgacc tgttcgttgc aacaaattga
       61 tgagcaatgc ttttttataa tgccaacttt gtacaaaaaa gttggcatga gctctccgcc
      121 gcccgcccgc agtggctttt accgccagga ggtgaccaag acggcctggg aggtgcgcgc
      181 cgtgtaccgg gacctgcagc ccgtgggctc gggcgcctac ggcgcggtgt gctcggccgt
      241 ggacggccgc accggcgcta aggtggccat caagaagctg tatcggccct tccagtccga
      301 gctgttcgcc aagcgcgcct accgcgagct gcgcctgctc aagcacatgc gccacgagaa
      361 cgtgatcggg ctgctggacg tattcactcc tgatgagacc ctggatgact tcacggactt
      421 ttacctggtg atgccgttca tgggcaccga cctgggcaag ctcatgaaac atgagaagct
      481 aggcgaggac cggatccagt tcctcgtgta ccagatgctg aaggggctga ggtatatcca
      541 cgctgccggc atcatccaca gagacctgaa gcccggcaac ctggctgtga acgaagactg
      601 tgagctgaag atcctggact tcggcctggc caggcaggca gacagtgaga tgactgggta
      661 cgtggtgacc cggtggtacc gggctcccga ggtcatcttg aattggatgc gctacacgca
      721 gacggtg
//
