LOCUS       sequence-29517-e         741 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 741)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 741)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PIM1
FEATURES             Location/Qualifiers
     source          1..741
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    9..108
                     /gene="mutant version of attL"
                     /label=attL1
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 gctcgggccc aataatgatt ttattttgac tgatagtgac ctgttcgttg caacaaattg
       61 atgagcaatg cttttttata atgccaactt tgtacaaaaa agttggcatg ctcttgtcca
      121 aaatcaactc gcttgcccac ctgcgcgccg cgccctgcaa cgacctgcac gccaccaagc
      181 tggcgcccgg caaggagaag gagcccctgg agtcgcagta ccaggtgggc ccgctactgg
      241 gcagcggcgg cttcggctcg gtctactcag gcatccgcgt ctccgacaac ttgccggtgg
      301 ccatcaaaca cgtggagaag gaccggattt ccgactgggg agagctgcct aatggcactc
      361 gagtgcccat ggaagtggtc ctgctgaaga aggtgagctc gggtttctcc ggcgtcatta
      421 ggctcctgga ctggttcgag aggcccgaca gtttcgtcct gatcctggag aggcccgagc
      481 cggtgcaaga tctcttcgac ttcatcacgg aaaggggagc cctgcaagag gagctggccc
      541 gcagcttctt ctggcaggtg ctggaggccg tgcggcactg ccacaactgc ggggtgctcc
      601 accgcgacat caaggacgaa aacatcctta tcgacctcaa tcgcggcgag ctcaagctca
      661 tcgacttcgg gtcgggggcg ctgctcaagg acaccgtcta cacggacttc gatgggaccc
      721 gagtgtatag ccctccagag t
//
