LOCUS       sequence-29587-e         678 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 678)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 678)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-TP53RK
FEATURES             Location/Qualifiers
     source          1..678
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    1..100
                     /gene="mutant version of attL"
                     /label=attL1
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 ccaataatga ttttattttg actgatagtg acctgttcgt tgcaacaaat tgatgagcaa
       61 tgctttttta taatgccaac tttgtacaaa aaagttggca tggcggcggc cagagctact
      121 acgccggccg atggcgagga gcccgccccg gaggctgagg ctctggccgc agcccgggag
      181 cggagcagcc gcttcttgag cggcctggag ctggtgaagc agggtgccga ggcgcgcgtg
      241 ttccgtggcc gcttccaggg ccgcgcggcg gtgatcaagc accgcttccc caagggctac
      301 cggcacccgg cgctggaggc gcggcttggc agacggcgga cggtgcagga ggcccgggcg
      361 ctcctccgct gtcgccgcgc tggaatatct gccccagttg tcttttttgt ggactatgct
      421 tccaactgct tatatatgga agaaattgaa ggctcagtga ctgttcgaga ttatattcag
      481 tccactatgg agactgaaaa aactccccag ggtctctcca acttagccaa gacaattggg
      541 caggttttgg ctcgaatgca cgatgaagac ctcattcatg gtgatctcac cacctccaac
      601 atgctcctga aaccccccct ggaacagctg aacattgtgc tcatagactt tgggctgagt
      661 ttcatttcag cacttcca
//
