LOCUS       sequence-29621-e         744 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 744)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 744)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PRKAR1A
FEATURES             Location/Qualifiers
     source          1..744
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    7..106
                     /gene="mutant version of attL"
                     /label=attL1
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 tcgggcccaa taatgatttt attttgactg atagtgacct gttcgttgca acaaattgat
       61 gagcaatgct tttttataat gccaactttg tacaaaaaag ttggcatgga gtctggcagt
      121 accgccgcca gtgaggaggc acgcagcctt cgagaatgtg agctctacgt ccagaagcat
      181 aacattcaag cgctgctcaa agattctatt gtgcagttgt gcactgctcg acctgagaga
      241 cccatggcat tcctcaggga atactttgag aggttggaga aggaggaggc aaaacagatt
      301 cagaatctgc agaaagcagg cactcgtaca gactcaaggg aggatgagat ttctcctcct
      361 ccacccaacc cagtggttaa aggtaggagg cgacgaggtg ctatcagcgc tgaggtctac
      421 acggaggaag atgcggcatc ctatgttaga aaggttatac caaaagatta caagacaatg
      481 gccgctttag ccaaagccat tgaaaagaat gtgctgtttt cacatcttga tgataatgag
      541 agaagtgata tttttgatgc catgttttcg gtctccttta tcgcaggaga gactgtgatt
      601 cagcaaggtg atgaagggga taacttctat gtgattgatc aaggagagac ggatgtctat
      661 gttaacaatg aatgggcaac cagtgttggg gaaggaggga gctttggaga acttgctttg
      721 atttatggaa caccgagagc agcc
//
