LOCUS       sequence-29627-e         668 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 668)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 668)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-MKNK2
FEATURES             Location/Qualifiers
     source          1..668
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    1..100
                     /gene="mutant version of attL"
                     /label=attL1
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
     protein_bind    complement(575..599)
                     /gene="mutant version of attB"
                     /label=attB2
                     /bound_moiety="BP Clonase(TM)"
                     /note="recombination site for the Gateway(R) BP reaction"
ORIGIN
        1 ccaataatga ttttattttg actgatagtg acctgttcgt tgcaacaaat tgatgagcaa
       61 tgctttttta taatgccaac tttgtacaaa aaagttggca tggccccgga ggtagtggag
      121 gccttcagcg aggaggctag catctacgac aagcgctgcg acctgtggag cctgggcgtc
      181 atcttgtata tcctactcag cggctacccg cccttcgtgg gccgctgtgg cagcgactgc
      241 ggctgggacc gcggcgaggc ctgccctgcc tgccagaaca tgctgtttga gagcatccag
      301 gagggcaagt acgagttccc cgacaaggac tgggcccaca tctcctgcgc tgccaaagac
      361 ctcatctcca agctgctggt ccgtgacgcc aagcagaggc tgagtgccgc ccaagtcctg
      421 cagcacccct gggttcaggg gtgcgccccg gagaacacct tgcccactcc catggtcctg
      481 cagaggtggg acagtcactt cctcctccct ccccacccct gtcgcatcca cgtgcgacct
      541 ggaggactgg tcagaaccgt tactgtgaat gagtgcccaa ctttcttgta caaagttggc
      601 attataagaa agcattgctt atcaatttgt tgcaacgaac aggtcactat cagtcaaaat
      661 aaaatcat
//
