LOCUS       sequence-29636-e         710 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 710)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 710)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PIK3R5
FEATURES             Location/Qualifiers
     source          1..710
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    13..112
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 tcagctggat ggcaaataat gattttattt tgactgatag tgacctgttc gttgcaacaa
       61 attgataagc aatgctttct tataatgcca actttgtaca agaaattggg tagggcagag
      121 ctccactgaa agtcatgatg ggcaggcaga gaagggagca gagatcaggt gcggcctggg
      181 ccggcaggtc aggaggcgtc tggggtggtg aggagaggtc gctcttctct ggcttgtagc
      241 acggtgagac ctcacatctg actacactct gcaggatctt tctctcatcc tggtccaggc
      301 acacagcaaa ggggcagctg ttggagccga tgatctgcac cttgtccact ttgatctgcg
      361 atgtgctaat ctggttaaag cccttcttgg atttggagtt ctgccttttc accacttctg
      421 tcaggtttag cgtcagggcc tccatgctgg aatccagctc ctcctgcttc cggcaggcct
      481 tgttgaggtt cacggaggta cagaccttct ccaggttgct ccagcgactt cgtccactga
      541 tggccccctt gctgtaaata atctgtagtg ttagaggaac agcctcccgg tcgccatcga
      601 tgcccagccg cttgctgcca ggacctgacg ccttgatggc acgtgtggca gcggagtgac
      661 ccagctccaa ggagtggatg aagatctctg tcgtcttctc cccagtgatg
//
