LOCUS       sequence-29637-e         706 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 706)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 706)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PIK3R5
FEATURES             Location/Qualifiers
     source          1..706
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    9..108
                     /gene="mutant version of attL"
                     /label=attL1
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 ctcgggccca aataatgatt ttattttgac tgatagtgac ctgttcgttg caacaaattg
       61 atgagcaatg cttttttata atgccaactt tgtacaaaaa agttggcatg gacagcggct
      121 acgtggagga cagcgaggag agctcctccg agtggccttg gaggcgtggc agccaggaac
      181 gccgaggcca ccgcaggcct gggcagaagt tcatcaggat ctataaactc ttcaagagca
      241 ccagccagct ggtactgcgg agggactctc ggagcctgga gggcagctcg gacacggccc
      301 tgcccctgag gcgggcaggg agcctctgca gccccctgga cgaaccagta tcaccccctt
      361 cccgggccca gcgctcccgc tccctgcccc agcccaaact cggtacccag ctgcccagct
      421 ggcttctggc ccctgcttca cgcccccagc gccgccgccc cttcctgagt ggagatgagg
      481 atcccaaggc ttccacgcta cgtgttgtgg tctttggctc cgatcggatt tcagggaagg
      541 tggctcgggc gtacagcaac cttcggcggc tggagaacaa tcgcccactc ctcacacggt
      601 tcttcaaact tcagttcttc tacgtgcctg tgaagcgaag tcatgggacc agccctggtg
      661 cctgtccacc ccctcggagc cagacgccct cacccccgac agactc
//
