LOCUS       sequence-29736-e         684 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 684)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 684)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-FGFR2
FEATURES             Location/Qualifiers
     source          1..684
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    73..97
                     /gene="mutant version of attB"
                     /label=attB1
                     /bound_moiety="BP Clonase(TM)"
                     /note="recombination site for the Gateway(R) BP reaction"
     protein_bind    496..507
                     /label=ZF binding site
                     /bound_moiety="CCR5TC zinc-finger domain"
                     /note="target sequence for the CCR5TC zinc-finger domain 
                     from the CCR5-224 (+) zinc-finger nuclease (Perez et al., 
                     2008; Gross et al., 2013)"
ORIGIN
        1 ataatgattt tattttgact gatagtgacc tgttcgttgc aacaaattga tgagcaatgc
       61 ttttttataa tgccaacttt gtacaaaaaa gttggcacca tggtcagctg gggtcgtttc
      121 atctgcctgg tcgtggtcac catggcaacc ttgtccctgg cccggccctc cttcagttta
      181 gttgaggata ccacattaga gccagaagag ccaccaacca aataccaaat ctctcaacca
      241 gaagtgtacg tggatgcgcc aggggagtcg ctagaggtgc gctgcctgtt gaaagatgcc
      301 gccgtgatca gttggactaa ggatggggtg cacttggggc ccaacaatag gacagtgctt
      361 attggggagt acttgcagat aaagggcgcc acgcctagag actccggcct ctatgcttgt
      421 actgccagta ggactgtaga cagtgaaact tggtacttca tggtgaatgt cacagatgcc
      481 atctcatccg gagatgatga ggatgacacc gatggtgcgg aagattttgt cagtgagaac
      541 agtaacaaca agagagcacc atactggacc aacacagaaa agatggaaaa gcggctccat
      601 gctgtgcctg cggccaacac tgtcaagttt cgctgcccag ccggggggaa cccaatgcca
      661 accatgcggt ggctgaaaaa cggg
//
