LOCUS       sequence-331091-       18310 bp    DNA     circular SYN 15-DEC-2025
DEFINITION  Final destination vector for single Gateway LR reaction.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      synthetic DNA construct
  ORGANISM  synthetic DNA construct
REFERENCE   1  (bases 1 to 18310)
  AUTHORS   Ursache R, Fujita S, Denervaud Tendon V, Geldner N
  TITLE     Combined fluorescent seed selection and multiplex CRISPR/Cas9 
            assembly for fast generation of multiple Arabidopsis mutants.
  JOURNAL   Plant Methods. 2021 Oct 30;17(1):111. doi: 
            10.1186/s13007-021-00811-9.
  PUBMED    34717688
REFERENCE   2  (bases 1 to 18310)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Plant 
            Methods."; date: "2021-10-30"; volume: "17(1):111. doi"; pages: " 
            10.1186/s13007-021-00811-9"
COMMENT     Sequence Label: pRU53
FEATURES             Location/Qualifiers
     source          1..18310
                     /mol_type="other DNA"
                     /organism="synthetic DNA construct"
     CDS             1187..1816
                     /codon_start=1
                     /product="stability protein from the Pseudomonas plasmid 
                     pVS1 (Heeb et al., 2000)"
                     /label=pVS1 StaA
                     /translation="MKVIAVLNQKGGSGKTTIATHLARALQLAGADVLLVDSDPQGSAR
                     DWAAVREDQPLTVVGIDRPTIDRDVKAIGRRDFVVIDGAPQAADLAVSAIKAADFVLIP
                     VQPSPYDIWATADLVELVKQRIEVTDGRLQAAFVVSRAIKGTRIGGEVAEALAGYELPI
                     LESRITQRVSYPGTAAAGTTVLESEPEGDAAREVQALAAEIKSKLI"
     CDS             2245..3318
                     /codon_start=1
                     /product="replication protein from the Pseudomonas plasmid 
                     pVS1 (Heeb et al., 2000)"
                     /label=pVS1 RepA
                     /translation="MSGRKPSGPVQIGAALGDDLVEKLKAAQAAQRQRIEAEARPGESW
                     QAAADRIRKESRQPPAAGAPSIRKPPKGDEQPDFFVPMLYDVGTRDSRSIMDVAVFRLS
                     KRDRRAGEVIRYELPDGHVEVSAGPAGMASVWDYDLVLMAVSHLTESMNRYREGKGDKP
                     GRVFRPHVADVLKFCRRADGGKQKDDLVETCIRLNTTHVAMQRTKKAKNGRLVTVSEGE
                     ALISRYKIVKSETGRPEYIEIELADWMYREITEGKNPDVLTVHPDYFLIDPGIGRFLYR
                     LARRAAGKAEARWLFKTIYERSGSAGEFKKFCFTVRKLIGSNDLPEYDLKEEAGQAGPI
                     LVMRYRNLIEGEASAGS"
     rep_origin      3384..3578
                     /label=pVS1 oriV
                     /note="origin of replication for the Pseudomonas plasmid 
                     pVS1 (Heeb et al., 2000)"
     primer_bind     complement(3814..3836)
                     /label=pGEX 3'
                     /note="pGEX vectors, reverse primer"
     misc_feature    3922..4062
                     /label=bom
                     /note="basis of mobility region from pBR322"
     primer_bind     3977..3996
                     /label=pRS-marker
                     /note="pRS vectors, use to sequence yeast selectable 
                     marker"
     primer_bind     complement(4077..4094)
                     /label=L4440
                     /note="L4440 vector, forward primer"
     rep_origin      complement(4248..4836)
                     /direction=LEFT
                     /label=ori
                     /note="high-copy-number ColE1/pMB1/pBR322/pUC origin of 
                     replication"
     primer_bind     complement(4328..4347)
                     /label=pBR322ori-F
                     /note="pBR322 origin, forward primer"
     CDS             complement(5082..5873)
                     /codon_start=1
                     /gene="aadA"
                     /product="aminoglycoside adenylyltransferase (Murphy, 
                     1985)"
                     /label=SmR
                     /note="confers resistance to spectinomycin and 
                     streptomycin"
                     /translation="MGEAVIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKPH
                     SDIDLLVTVTVRLDETTRRALINDLLETSASPGESEILRAVEVTIVVHDDIIPWRYPAK
                     RELQFGEWQRNDILAGIFEPATIDIDLAILLTKAREHSVALVGPAAEELFDPVPEQDLF
                     EALNETLTLWNSPPDWAGDERNVVLTLSRIWYSAVTGKIAPKDVAADWAMERLPAQYQP
                     VILEARQAYLGQEEDRLASRADQLEEFVHYVKGEITKVVGK"
     misc_feature    6394..6418
                     /label=LB T-DNA repeat
                     /note="left border repeat from nopaline C58 T-DNA"
     protein_bind    6595..6616
                     /label=CAP binding site
                     /bound_moiety="E. coli catabolite activator protein"
                     /note="CAP binding activates transcription in the presence 
                     of cAMP."
     promoter        join(6631..6636,6637..6654,6655..6661)
                     /label=lac promoter
                     /note="promoter for the E. coli lac operon"
     protein_bind    6669..6685
                     /label=lac operator
                     /bound_moiety="lac repressor encoded by lacI"
                     /note="The lac repressor binds to the lac operator to 
                     inhibit transcription in E. coli. This inhibition can be 
                     relieved by adding lactose or 
                     isopropyl-beta-D-thiogalactopyranoside (IPTG)."
     primer_bind     6674..6696
                     /label=M13/pUC Reverse
                     /note="In lacZ gene"
     primer_bind     6693..6709
                     /label=M13 rev
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     primer_bind     6693..6709
                     /label=M13 Reverse
                     /note="In lacZ gene. Also called M13-rev"
     CDS             8085..8150
                     /codon_start=1
                     /product="three tandem FLAG(R) epitope tags, followed by an
                     enterokinase cleavage site"
                     /label=3xFLAG
                     /translation="DYKDHDGDYKDHDIDYKDDDDK"
     CDS             8157..8177
                     /codon_start=1
                     /product="nuclear localization signal of SV40 (simian virus
                     40) large T antigen"
                     /label=SV40 NLS
                     /translation="PKKKRKV"
     CDS             8202..12302
                     /codon_start=1
                     /product="Cas9 (Csn1) endonuclease from the Streptococcus 
                     pyogenes Type II CRISPR/Cas system"
                     /label=Cas9
                     /note="generates RNA-guided double strand breaks in DNA"
                     /translation="DKKYSIGLDIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKN
                     LIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESF
                     LVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKF
                     RGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLE
                     NLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQI
                     GDQYADLFLAAKNLSDAILLSDILRVNTEITKAPLSASMIKRYDEHHQDLTLLKALVRQ
                     QLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLR
                     KQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGN
                     SRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYF
                     TVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDS
                     VEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERL
                     KTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQ
                     LIHDDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRH
                     KPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYL
                     YYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVPS
                     EEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKHV
                     AQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLN
                     AVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIGKATAKYFFYSNIMNFFKTE
                     ITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKE
                     SILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGIT
                     IMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNEL
                     ALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADA
                     NLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLD
                     ATLIHQSITGLYETRIDLSQLGGD"
     CDS             8202..12302
                     /codon_start=1
                     /product="Cas9 (Csn1) endonuclease from the Streptococcus 
                     pyogenes Type II CRISPR/Cas system"
                     /label=Cas9
                     /note="generates RNA-guided double strand breaks in DNA"
                     /translation="DKKYSIGLDIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKN
                     LIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESF
                     LVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKF
                     RGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLE
                     NLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQI
                     GDQYADLFLAAKNLSDAILLSDILRVNTEITKAPLSASMIKRYDEHHQDLTLLKALVRQ
                     QLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLR
                     KQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGN
                     SRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYF
                     TVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDS
                     VEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERL
                     KTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQ
                     LIHDDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRH
                     KPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYL
                     YYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVPS
                     EEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKHV
                     AQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLN
                     AVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIGKATAKYFFYSNIMNFFKTE
                     ITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKE
                     SILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGIT
                     IMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNEL
                     ALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADA
                     NLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLD
                     ATLIHQSITGLYETRIDLSQLGGD"
     RBS             12215..12223
                     /label=Shine-Dalgarno sequence
                     /note="full consensus sequence for ribosome-binding sites 
                     upstream of start codons in E. coli; complementary to a 
                     region in the 3' end of the 16S rRNA (Chen et al., 1994)"
     CDS             12303..12350
                     /codon_start=1
                     /product="bipartite nuclear localization signal from 
                     nucleoplasmin"
                     /label=nucleoplasmin NLS
                     /translation="KRPAATKKAGQAKKKK"
     protein_bind    13018..13142
                     /gene="mutant version of attR"
                     /label=attR1
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
     promoter        join(13167..13172,13173..13190,13191..13197)
                     /label=lac UV5 promoter
                     /note="E. coli lac promoter with an ""up"" mutation"
     CDS             13251..13931
                     /codon_start=1
                     /product="chloramphenicol acetyltransferase"
                     /label=CmR
                     /note="confers resistance to chloramphenicol"
                     /translation="MEKKITGYTTVDISQWHRKEHFEAFQSVAQCTYNQTVQLDITAFL
                     KTVKKNKHKFYPAFIHILARLMNAHPEFRMAMKDGELVIWDSVHPCYTVFHEQTETFSS
                     LWSEYHDDFRQFLHIYSQDVACYGENLAYFPKGFIENMFFVSANPWVSFTSFDLNVANM
                     DNFFAPVFTMGKYYTQGDKVLMPLAIQVHHAVCDGFHVGRMLNELQQYCDEWQAGRNLE
                     DPAY"
     primer_bind     complement(13317..13336)
                     /label=CAT-R
                     /note="Chloramphenicol resistance gene, reverse primer"
     CDS             14251..14556
                     /codon_start=1
                     /gene="ccdB"
                     /product="CcdB, a bacterial toxin that poisons DNA gyrase"
                     /label=ccdB
                     /note="Plasmids containing the ccdB gene cannot be 
                     propagated in standard E. coli strains."
                     /translation="MQFKVYTYKRESRYRLFVDVQSDIIDTPGRRMVIPLASARLLSDK
                     VPRELYPVVHIGDESWRMMTTDMASVPVSVIGEEVADLSHRENDIKNAINLMFWGI"
     primer_bind     14435..14454
                     /label=ccdB-fwd
                     /note="ccdB gene, forward primer"
     protein_bind    complement(14597..14721)
                     /gene="mutant version of attR"
                     /label=attR2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
     CDS             16975..17670
                     /codon_start=1
                     /product="monomeric far-red fluorescent protein (Shcherbo 
                     et al., 2009)"
                     /label=mKate2
                     /note="mammalian codon-optimized"
                     /translation="MSELIKENMHMKLYMEGTVNNHHFKCTSEGEGKPYEGTQTMRIKV
                     VEGGPLPFAFDILATSFMYGSRTFINHTQGIPDFFKQSFPEGFTWERVTTYEDGGVLTA
                     TQDTSLQDGCLIYNVKIRGVNFPSNGPVMQKKTLGWEANTEMLYPADGGLEGRSDMALK
                     LVGGGHLICNFKTTYRSKKPAKNLKMPGVYYVDHRLERIKEADKETYVEQHEVAVARYC
                     DLPSKLGHK"
     terminator      complement(17669..17920)
                     /label=NOS terminator
                     /note="nopaline synthase terminator and poly(A) signal"
     primer_bind     complement(17930..17947)
                     /label=M13 Forward
                     /note="In lacZ gene. Also called M13-F20 or M13 (-21) 
                     Forward"
     primer_bind     complement(17930..17946)
                     /label=M13 fwd
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     primer_bind     complement(17939..17961)
                     /label=M13/pUC Forward
                     /note="In lacZ gene"
     misc_feature    18142..18166
                     /label=RB T-DNA repeat
                     /note="right border repeat from nopaline C58 T-DNA"
ORIGIN
        1 agtactttga tccaacccct ccgctgctat agtgcagtcg gcttctgacg ttcagtgcag
       61 ccgtcttctg aaaacgacat gtcgcacaag tcctaagtta cgcgacaggc tgccgccctg
      121 cccttttcct ggcgttttct tgtcgcgtgt tttagtcgca taaagtagaa tacttgcgac
      181 tagaaccgga gacattacgc catgaacaag agcgccgccg ctggcctgct gggctatgcc
      241 cgcgtcagca ccgacgacca ggacttgacc aaccaacggg ccgaactgca cgcggccggc
      301 tgcaccaagc tgttttccga gaagatcacc ggcaccaggc gcgaccgccc ggagctggcc
      361 aggatgcttg accacctacg ccctggcgac gttgtgacag tgaccaggct agaccgcctg
      421 gcccgcagca cccgcgacct actggacatt gccgagcgca tccaggaggc cggcgcgggc
      481 ctgcgtagcc tggcagagcc gtgggccgac accaccacgc cggccggccg catggtgttg
      541 accgtgttcg ccggcattgc cgagttcgag cgttccctaa tcatcgaccg cacccggagc
      601 gggcgcgagg ccgccaaggc ccgaggcgtg aagtttggcc cccgccctac cctcaccccg
      661 gcacagatcg cgcacgcccg cgagctgatc gaccaggaag gccgcaccgt gaaagaggcg
      721 gctgcactgc ttggcgtgca tcgctcgacc ctgtaccgcg cacttgagcg cagcgaggaa
      781 gtgacgccca ccgaggccag gcggcgcggt gccttccgtg aggacgcatt gaccgaggcc
      841 gacgccctgg cggccgccga gaatgaacgc caagaggaac aagcatgaaa ccgcaccagg
      901 acggccagga cgaaccgttt ttcattaccg aagagatcga ggcggagatg atcgcggccg
      961 ggtacgtgtt cgagccgccc gcgcacgtct caaccgtgcg gctgcatgaa atcctggccg
     1021 gtttgtctga tgccaagctg gcggcctggc cggccagctt ggccgctgaa gaaaccgagc
     1081 gccgccgtct aaaaaggtga tgtgtatttg agtaaaacag cttgcgtcat gcggtcgctg
     1141 cgtatatgat gcgatgagta aataaacaaa tacgcaaggg gaacgcatga aggttatcgc
     1201 tgtacttaac cagaaaggcg ggtcaggcaa gacgaccatc gcaacccatc tagcccgcgc
     1261 cctgcaactc gccggggccg atgttctgtt agtcgattcc gatccccagg gcagtgcccg
     1321 cgattgggcg gccgtgcggg aagatcaacc gctaaccgtt gtcggcatcg accgcccgac
     1381 gattgaccgc gacgtgaagg ccatcggccg gcgcgacttc gtagtgatcg acggagcgcc
     1441 ccaggcggcg gacttggctg tgtccgcgat caaggcagcc gacttcgtgc tgattccggt
     1501 gcagccaagc ccttacgaca tatgggccac cgccgacctg gtggagctgg ttaagcagcg
     1561 cattgaggtc acggatggaa ggctacaagc ggcctttgtc gtgtcgcggg cgatcaaagg
     1621 cacgcgcatc ggcggtgagg ttgccgaggc gctggccggg tacgagctgc ccattcttga
     1681 gtcccgtatc acgcagcgcg tgagctaccc aggcactgcc gccgccggca caaccgttct
     1741 tgaatcagaa cccgagggcg acgctgcccg cgaggtccag gcgctggccg ctgaaattaa
     1801 atcaaaactc atttgagtta atgaggtaaa gagaaaatga gcaaaagcac aaacacgcta
     1861 agtgccggcc gtccgagcgc acgcagcagc aaggctgcaa cgttggccag cctggcagac
     1921 acgccagcca tgaagcgggt caactttcag ttgccggcgg aggatcacac caagctgaag
     1981 atgtacgcgg tacgccaagg caagaccatt accgagctgc tatctgaata catcgcgcag
     2041 ctaccagagt aaatgagcaa atgaataaat gagtagatga attttagcgg ctaaaggagg
     2101 cggcatggaa aatcaagaac aaccaggcac cgacgccgtg gaatgcccca tgtgtggagg
     2161 aacgggcggt tggccaggcg taagcggctg ggttgtctgc cggccctgca atggcactgg
     2221 aacccccaag cccgaggaat cggcgtgagc ggtcgcaaac catccggccc ggtacaaatc
     2281 ggcgcggcgc tgggtgatga cctggtggag aagttgaagg ccgcgcaggc cgcccagcgg
     2341 caacgcatcg aggcagaagc acgccccggt gaatcgtggc aagcggccgc tgatcgaatc
     2401 cgcaaagaat cccggcaacc gccggcagcc ggtgcgccgt cgattaggaa gccgcccaag
     2461 ggcgacgagc aaccagattt tttcgttccg atgctctatg acgtgggcac ccgcgatagt
     2521 cgcagcatca tggacgtggc cgttttccgt ctgtcgaagc gtgaccgacg agctggcgag
     2581 gtgatccgct acgagcttcc agacgggcac gtagaggttt ccgcagggcc ggccggcatg
     2641 gccagtgtgt gggattacga cctggtactg atggcggttt cccatctaac cgaatccatg
     2701 aaccgatacc gggaagggaa gggagacaag cccggccgcg tgttccgtcc acacgttgcg
     2761 gacgtactca agttctgccg gcgagccgat ggcggaaagc agaaagacga cctggtagaa
     2821 acctgcattc ggttaaacac cacgcacgtt gccatgcagc gtacgaagaa ggccaagaac
     2881 ggccgcctgg tgacggtatc cgagggtgaa gccttgatta gccgctacaa gatcgtaaag
     2941 agcgaaaccg ggcggccgga gtacatcgag atcgagctag ctgattggat gtaccgcgag
     3001 atcacagaag gcaagaaccc ggacgtgctg acggttcacc ccgattactt tttgatcgat
     3061 cccggcatcg gccgttttct ctaccgcctg gcacgccgcg ccgcaggcaa ggcagaagcc
     3121 agatggttgt tcaagacgat ctacgaacgc agtggcagcg ccggagagtt caagaagttc
     3181 tgtttcaccg tgcgcaagct gatcgggtca aatgacctgc cggagtacga tttgaaggag
     3241 gaggcggggc aggctggccc gatcctagtc atgcgctacc gcaacctgat cgagggcgaa
     3301 gcatccgccg gttcctaatg tacggagcag atgctagggc aaattgccct agcaggggaa
     3361 aaaggtcgaa aaggtctctt tcctgtggat agcacgtaca ttgggaaccc aaagccgtac
     3421 attgggaacc ggaacccgta cattgggaac ccaaagccgt acattgggaa ccggtcacac
     3481 atgtaagtga ctgatataaa agagaaaaaa ggcgattttt ccgcctaaaa ctctttaaaa
     3541 cttattaaaa ctcttaaaac ccgcctggcc tgtgcataac tgtctggcca gcgcacagcc
     3601 gaagagctgc aaaaagcgcc tacccttcgg tcgctgcgct ccctacgccc cgccgcttcg
     3661 cgtcggccta tcgcggccgc tggccgctca aaaatggctg gcctacggcc aggcaatcta
     3721 ccagggcgcg gacaagccgc gccgtcgcca ctcgaccgcc ggcgcccaca tcaaggcacc
     3781 ctgcctcgcg cgtttcggtg atgacggtga aaacctctga cacatgcagc tcccggagac
     3841 ggtcacagct tgtctgtaag cggatgccgg gagcagacaa gcccgtcagg gcgcgtcagc
     3901 gggtgttggc gggtgtcggg gcgcagccat gacccagtca cgtagcgata gcggagtgta
     3961 tactggctta actatgcggc atcagagcag attgtactga gagtgcacca tatgcggtgt
     4021 gaaataccgc acagatgcgt aaggagaaaa taccgcatca ggcgctcttc cgcttcctcg
     4081 ctcactgact cgctgcgctc ggtcgttcgg ctgcggcgag cggtatcagc tcactcaaag
     4141 gcggtaatac ggttatccac agaatcaggg gataacgcag gaaagaacat gtgagcaaaa
     4201 ggccagcaaa aggccaggaa ccgtaaaaag gccgcgttgc tggcgttttt ccataggctc
     4261 cgcccccctg acgagcatca caaaaatcga cgctcaagtc agaggtggcg aaacccgaca
     4321 ggactataaa gataccaggc gtttccccct ggaagctccc tcgtgcgctc tcctgttccg
     4381 accctgccgc ttaccggata cctgtccgcc tttctccctt cgggaagcgt ggcgctttct
     4441 catagctcac gctgtaggta tctcagttcg gtgtaggtcg ttcgctccaa gctgggctgt
     4501 gtgcacgaac cccccgttca gcccgaccgc tgcgccttat ccggtaacta tcgtcttgag
     4561 tccaacccgg taagacacga cttatcgcca ctggcagcag ccactggtaa caggattagc
     4621 agagcgaggt atgtaggcgg tgctacagag ttcttgaagt ggtggcctaa ctacggctac
     4681 actagaagga cagtatttgg tatctgcgct ctgctgaagc cagttacctt cggaaaaaga
     4741 gttggtagct cttgatccgg caaacaaacc accgctggta gcggtggttt ttttgtttgc
     4801 aagcagcaga ttacgcgcag aaaaaaagga tctcaagaag atcctttgat cttttctacg
     4861 gggtctgacg ctcagtggaa cgaaaactca cgttaaggga ttttggtcat gcatgatata
     4921 tctcccaatt tgtgtagggc ttattatgca cgcttaaaaa taataaaagc agacttgacc
     4981 tgatagtttg gctgtgagca attatgtgct tagtgcatct aacgcttgag ttaagccgcg
     5041 ccgcgaagcg gcgtcggctt gaacgaattt ctagctagac attatttgcc gactaccttg
     5101 gtgatctcgc ctttcacgta gtggacaaat tcttccaact gatctgcgcg cgaggccaag
     5161 cgatcttctt cttgtccaag ataagcctgt ctagcttcaa gtatgacggg ctgatactgg
     5221 gccggcaggc gctccattgc ccagtcggca gcgacatcct tcggcgcgat tttgccggtt
     5281 actgcgctgt accaaatgcg ggacaacgta agcactacat ttcgctcatc gccagcccag
     5341 tcgggcggcg agttccatag cgttaaggtt tcatttagcg cctcaaatag atcctgttca
     5401 ggaaccggat caaagagttc ctccgccgct ggacctacca aggcaacgct atgttctctt
     5461 gcttttgtca gcaagatagc cagatcaatg tcgatcgtgg ctggctcgaa gatacctgca
     5521 agaatgtcat tgcgctgcca ttctccaaat tgcagttcgc gcttagctgg ataacgccac
     5581 ggaatgatgt cgtcgtgcac aacaatggtg acttctacag cgcggagaat ctcgctctct
     5641 ccaggggaag ccgaagtttc caaaaggtcg ttgatcaaag ctcgccgcgt tgtttcatca
     5701 agccttacgg tcaccgtaac cagcaaatca atatcactgt gtggcttcag gccgccatcc
     5761 actgcggagc cgtacaaatg tacggccagc aacgtcggtt cgagatggcg ctcgatgacg
     5821 ccaactacct ctgatagttg agtcgatact tcggcgatca ccgcttcccc catgatgttt
     5881 aactttgttt tagggcgact gccctgctgc gtaacatcgt tgctgctcca taacatcaaa
     5941 catcgaccca cggcgtaacg cgcttgctgc ttggatgccc gaggcataga ctgtacccca
     6001 aaaaaacagt cataacaagc catgaaaacc gccactgcgc cgttaccacc gctgcgttcg
     6061 gtcaaggttc tggaccagtt gcgtgagcgc atacgctact tgcattacag cttacgaacc
     6121 gaacaggctt atgtccactg ggttcgtgcc cgaattgatc acaggcagca acgctctgtc
     6181 atcgttacaa tcaacatgct accctccgcg agatcatccg tgtttcaaac ccggcagctt
     6241 agttgccgtt cttccgaata gcatcggtaa catgagcaaa gtctgccgcc ttacaacggc
     6301 tctcccgctg acgccgtccc ggactgatgg gctgcctgta tcgagtggtg attttgtgcc
     6361 gagctgccgg tcggggagct gttggctggc tggtggcagg atatattgtg gtgtaaacaa
     6421 attgacgctt agacaactta ataacacatt gcggacgttt ttaatgtact gaattaacgc
     6481 cgaattgctc tagccaatac gcaaaccgcc tctccccgcg cgttggccga ttcattaatg
     6541 cagctggcac gacaggtttc ccgactggaa agcgggcagt gagcgcaacg caattaatgt
     6601 gagttagctc actcattagg caccccaggc tttacacttt atgcttccgg ctcgtatgtt
     6661 gtgtggaatt gtgagcggat aacaatttca cacaggaaac agctatgaca tgattacgaa
     6721 ttcgaataaa agcatttgcg tttggtttat cattgcgttt atacaaggac agagatccac
     6781 tgagctggaa tagcttaaaa ccattatcag aacaaaataa accatttttt gttaagaatc
     6841 agagcatagt aaacaacaga aacaacctaa gagaggtaac ttgtccaaga agatagctaa
     6901 ttatatctat tttataaaag ttatcatagt ttgtaagtca caaaagatgc aaataacaga
     6961 gaaactagga gacttgagaa tatacattct tgtatatttg tattcgagat tgtgaaaatt
     7021 tgaccataag tttaaattct taaaaagata tatctgatct aggtgatggt tatagactgt
     7081 aattttacca catgtttaat gatggatagt gacacacatg acacatcgac aacactatag
     7141 catcttattt agattacaac atgaaatttt tctgtaatac atgtctttgt acataattta
     7201 aaagtaattc ctaagaaata tatttataca aggagtttaa agaaaacata gcataaagtt
     7261 caatgagtag taaaaaccat atacagtata tagcataaag ttcaatgagt ttattacaaa
     7321 agcattggtt cactttctgt aacacgacgt taaaccttcg tctccaatag gagcgctact
     7381 gattcaacat gccaatatat actaaatacg tttctacagt caaatgcttt aacgtttcat
     7441 gattaagtga ctatttaccg tcaatccttt cccattcctc ccactaatcc aactttttaa
     7501 ttactcttaa atcaccacta agctagtaac gcctatcatg aattagctct actaaatcta
     7561 gcaacctttc aaatttgcag tattgcaggt gtctctgtgt ctttaaaata gttgccttat
     7621 gatttcttcg gtttcaagat gatcaaatag ttatagattt catgctcaca catgctcatt
     7681 agatgtgtac atactttact tacccaaatc tattttctcg caaagatttt gatggtaaag
     7741 ctgatttggt tctattgaac taaatcaaac gagtttcaga ctgagtgatt ctaatccggc
     7801 ccattagccc ctaaacagac ccactaatta cgcagctttt aatagagtaa ttacacctag
     7861 tttacccact aaaccactaa gcactaatta tctcacaatc taatgagctt ccctcgtaat
     7921 tacttgggct ttcactctac catttatttg taacagtcaa gtctctactg tctctatata
     7981 aactctctaa agttaacaca caattctcat cacaaacaaa tcaaccaaag caacttctac
     8041 tctttcttct ttcgacctta tcaatctgtt gagaaatcta gatggattac aaggaccacg
     8101 acggggatta caaggaccac gacattgatt acaaggatga tgatgacaag atggctccga
     8161 agaagaagag gaaggttggc atccacgggg tgccagctgc tgacaagaag tactcgatcg
     8221 gcctcgatat tgggactaac tctgttggct gggccgtgat caccgacgag tacaaggtgc
     8281 cctcaaagaa gttcaaggtc ctgggcaaca ccgatcggca ttccatcaag aagaatctca
     8341 ttggcgctct cctgttcgac agcggcgaga cggctgaggc tacgcggctc aagcgcaccg
     8401 cccgcaggcg gtacacgcgc aggaagaatc gcatctgcta cctgcaggag attttctcca
     8461 acgagatggc gaaggttgac gattctttct tccacaggct ggaggagtca ttcctcgtgg
     8521 aggaggataa gaagcacgag cggcatccaa tcttcggcaa cattgtcgac gaggttgcct
     8581 accacgagaa gtaccctacg atctaccatc tgcggaagaa gctcgtggac tccacagata
     8641 aggcggacct ccgcctgatc tacctcgctc tggcccacat gattaagttc aggggccatt
     8701 tcctgatcga gggggatctc aacccggaca atagcgatgt tgacaagctg ttcatccagc
     8761 tcgtgcagac gtacaaccag ctcttcgagg agaaccccat taatgcgtca ggcgtcgacg
     8821 cgaaggctat cctgtccgct aggctctcga agtctcggcg cctcgagaac ctgatcgccc
     8881 agctgccggg cgagaagaag aacggcctgt tcgggaatct cattgcgctc agcctggggc
     8941 tcacgcccaa cttcaagtcg aatttcgatc tcgctgagga cgccaagctg cagctctcca
     9001 aggacacata cgacgatgac ctggataacc tcctggccca gatcggcgat cagtacgcgg
     9061 acctgttcct cgctgccaag aatctgtcgg acgccatcct cctgtctgat attctcaggg
     9121 tgaacaccga gattacgaag gctccgctct cagcctccat gatcaagcgc tacgacgagc
     9181 accatcagga tctgaccctc ctgaaggcgc tggtcaggca gcagctcccc gagaagtaca
     9241 aggagatctt cttcgatcag tcgaagaacg gctacgctgg gtacattgac ggcggggcct
     9301 ctcaggagga gttctacaag ttcatcaagc cgattctgga gaagatggac ggcacggagg
     9361 agctgctggt gaagctcaat cgcgaggacc tcctgaggaa gcagcggaca ttcgataacg
     9421 gcagcatccc acaccagatt catctcgggg agctgcacgc tatcctgagg aggcaggagg
     9481 acttctaccc tttcctcaag gataaccgcg agaagatcga gaagattctg actttcagga
     9541 tcccgtacta cgtcggccca ctcgctaggg gcaactcccg cttcgcttgg atgacccgca
     9601 agtcagagga gacgatcacg ccgtggaact tcgaggaggt ggtcgacaag ggcgctagcg
     9661 ctcagtcgtt catcgagagg atgacgaatt tcgacaagaa cctgccaaat gagaaggtgc
     9721 tccctaagca ctcgctcctg tacgagtact tcacagtcta caacgagctg actaaggtga
     9781 agtatgtgac cgagggcatg aggaagccgg ctttcctgtc tggggagcag aagaaggcca
     9841 tcgtggacct cctgttcaag accaaccgga aggtcacggt taagcagctc aaggaggact
     9901 acttcaagaa gattgagtgc ttcgattcgg tcgagatctc tggcgttgag gaccgcttca
     9961 acgcctccct ggggacctac cacgatctcc tgaagatcat taaggataag gacttcctgg
    10021 acaacgagga gaatgaggat atcctcgagg acattgtgct gacactcact ctgttcgagg
    10081 accgggagat gatcgaggag cgcctgaaga cttacgccca tctcttcgat gacaaggtca
    10141 tgaagcagct caagaggagg aggtacaccg gctgggggag gctgagcagg aagctcatca
    10201 acggcattcg ggacaagcag tccgggaaga cgatcctcga cttcctgaag agcgatggct
    10261 tcgcgaaccg caatttcatg cagctgattc acgatgacag cctcacattc aaggaggata
    10321 tccagaaggc tcaggtgagc ggccaggggg actcgctgca cgagcatatc gcgaacctcg
    10381 ctggctcgcc agctatcaag aaggggattc tgcagaccgt gaaggttgtg gacgagctgg
    10441 tgaaggtcat gggcaggcac aagcctgaga acatcgtcat tgagatggcc cgggagaatc
    10501 agaccacgca gaagggccag aagaactcac gcgagaggat gaagaggatc gaggagggca
    10561 ttaaggagct ggggtcccag atcctcaagg agcacccggt ggagaacacg cagctgcaga
    10621 atgagaagct ctacctgtac tacctccaga atggccgcga tatgtatgtg gaccaggagc
    10681 tggatattaa caggctcagc gattacgacg tcgatcatat cgttccacag tcattcctga
    10741 aggatgactc cattgacaac aaggtcctca ccaggtcgga caagaaccgg ggcaagtctg
    10801 ataatgttcc ttcagaggag gtcgttaaga agatgaagaa ctactggcgc cagctcctga
    10861 atgccaagct gatcacgcag cggaagttcg ataacctcac aaaggctgag aggggcgggc
    10921 tctctgagct ggacaaggcg ggcttcatca agaggcagct ggtcgagaca cggcagatca
    10981 ctaagcacgt tgcgcagatt ctcgactcac ggatgaacac taagtacgat gagaatgaca
    11041 agctgatccg cgaggtgaag gtcatcaccc tgaagtcaaa gctcgtctcc gacttcagga
    11101 aggatttcca gttctacaag gttcgggaga tcaacaatta ccaccatgcc catgacgcgt
    11161 acctgaacgc ggtggtcggc acagctctga tcaagaagta cccaaagctc gagagcgagt
    11221 tcgtgtacgg ggactacaag gtttacgatg tgaggaagat gatcgccaag tcggagcagg
    11281 agattggcaa ggctaccgcc aagtacttct tctactctaa cattatgaat ttcttcaaga
    11341 cagagatcac tctggccaat ggcgagatcc ggaagcgccc cctcatcgag acgaacggcg
    11401 agacggggga gatcgtgtgg gacaagggca gggatttcgc gaccgtcagg aaggttctct
    11461 ccatgccaca agtgaatatc gtcaagaaga cagaggtcca gactggcggg ttctctaagg
    11521 agtcaattct gcctaagcgg aacagcgaca agctcatcgc ccgcaagaag gactgggatc
    11581 cgaagaagta cggcgggttc gacagcccca ctgtggccta ctcggtcctg gttgtggcga
    11641 aggttgagaa gggcaagtcc aagaagctca agagcgtgaa ggagctgctg gggatcacga
    11701 ttatggagcg ctccagcttc gagaagaacc cgatcgattt cctggaggcg aagggctaca
    11761 aggaggtgaa gaaggacctg atcattaagc tccccaagta ctcactcttc gagctggaga
    11821 acggcaggaa gcggatgctg gcttccgctg gcgagctgca gaaggggaac gagctggctc
    11881 tgccgtccaa gtatgtgaac ttcctctacc tggcctccca ctacgagaag ctcaagggca
    11941 gccccgagga caacgagcag aagcagctgt tcgtcgagca gcacaagcat tacctcgacg
    12001 agatcattga gcagatttcc gagttctcca agcgcgtgat cctggccgac gcgaatctgg
    12061 ataaggtcct ctccgcgtac aacaagcacc gcgacaagcc aatcagggag caggctgaga
    12121 atatcattca tctcttcacc ctgacgaacc tcggcgcccc tgctgctttc aagtacttcg
    12181 acacaactat cgatcgcaag aggtacacaa gcactaagga ggtcctggac gcgaccctca
    12241 tccaccagtc gattaccggc ctctacgaga cgcgcatcga cctgtctcag ctcgggggcg
    12301 acaagcggcc agcggcgacg aagaaggcgg ggcaggcgaa gaagaagaag tgagctcaga
    12361 gctttcgttc gtatcatcgg tttcgacaac gttcgtcaag ttcaatgcat cagtttcatt
    12421 gcgcacacac cagaatccta ctgagtttga gtattatggc attgggaaaa ctgtttttct
    12481 tgtaccattt gttgtgcttg taatttactg tgttttttat tcggttttcg ctatcgaact
    12541 gtgaaatgga aatggatgga gaagagttaa tgaatgatat ggtccttttg ttcattctca
    12601 aattaatatt atttgttttt tctcttattt gttgtgtgtt gaatttgaaa ttataagaga
    12661 tatgcaaaca ttttgttttg agtaaaaatg tgtcaaatcg tggcctctaa tgaccgaagt
    12721 taatatgagg agtaaaacac ttgtagttgt accattatgc ttattcacta ggcaacaaat
    12781 atattttcag acctagaaaa gctgcaaatg ttactgaata caagtatgtc ctcttgtgtt
    12841 ttagacattt atgaactttc ctttatgtaa ttttccagaa tccttgtcag attctaatca
    12901 ttgctttata attatagtta tactcatgga tttgtagttg agtatgaaaa tattttttaa
    12961 tgcattttat gacttgccaa ttgattgaca acgagctccc taggcctgtt atccctaaca
    13021 agtttgtaca aaaaagctga acgagaaacg taaaatgata taaatatcaa tatattaaat
    13081 tagattttgc ataaaaaaca gactacataa tactgtaaaa cacaacatat ccagtcacta
    13141 tggcggccgc attaggcacc ccaggcttta cactttatgc ttccggctcg tataatgtgt
    13201 ggattttgag ttaggatccg tcgagatttt caggagctaa ggaagctaaa atggagaaaa
    13261 aaatcactgg atataccacc gttgatatat cccaatggca tcgtaaagaa cattttgagg
    13321 catttcagtc agttgctcaa tgtacctata accagaccgt tcagctggat attacggcct
    13381 ttttaaagac cgtaaagaaa aataagcaca agttttatcc ggcctttatt cacattcttg
    13441 cccgcctgat gaatgctcat ccggaattcc gtatggcaat gaaagacggt gagctggtga
    13501 tatgggatag tgttcaccct tgttacaccg ttttccatga gcaaactgaa acgttttcat
    13561 cgctctggag tgaataccac gacgatttcc ggcagtttct acacatatat tcgcaagatg
    13621 tggcgtgtta cggtgaaaac ctggcctatt tccctaaagg gtttattgag aatatgtttt
    13681 tcgtctcagc caatccctgg gtgagtttca ccagttttga tttaaacgtg gccaatatgg
    13741 acaacttctt cgcccccgtt ttcaccatgg gcaaatatta tacgcaaggc gacaaggtgc
    13801 tgatgccgct ggcgattcag gttcatcatg ccgtttgtga tggcttccat gtcggcagaa
    13861 tgcttaatga attacaacag tactgcgatg agtggcaggc ggggcgtaat ctagaggatc
    13921 cggcttacta aaagccagat aacagtatgc gtatttgcgc gctgattttt gcggtataag
    13981 aatatatact gatatgtata cccgaagtat gtcaaaaaga ggtatgctat gaagcagcgt
    14041 attacagtga cagttgacag cgacagctat cagttgctca aggcatatat gatgtcaata
    14101 tctccggtct ggtaagcaca accatgcaga atgaagcccg tcgtctgcgt gccgaacgct
    14161 ggaaagcgga aaatcaggaa gggatggctg aggtcgcccg gtttattgaa atgaacggct
    14221 cttttgctga cgagaacagg ggctggtgaa atgcagttta aggtttacac ctataaaaga
    14281 gagagccgtt atcgtctgtt tgtggatgta cagagtgata ttattgacac gcccgggcga
    14341 cggatggtga tccccctggc cagtgcacgt ctgctgtcag ataaagtccc ccgtgaactt
    14401 tacccggtgg tgcatatcgg ggatgaaagc tggcgcatga tgaccaccga tatggccagt
    14461 gtgccggtct ccgttatcgg ggaagaagtg gctgatctca gccaccgcga aaatgacatc
    14521 aaaaacgcca ttaacctgat gttctgggga atataaatgt caggctccct tatacacagc
    14581 cagtctgcag gtcgaccata gtgactggat atgttgtgtt ttacagtatt atgtagtctg
    14641 ttttttatgc aaaatctaat ttaatatatt gatatttata tcattttacg tttctcgttc
    14701 agctttcttg tacaaagtgg ttcgataatt ccgatccagc ctaggcccgg gcctgaggac
    14761 gcgtccatgg ttaattaaga cgtccggacc gactagtgga tcctctagag tcgacctgca
    14821 ggcatgcaag cttcttcaag tgtatgtagg tatagtaaca tgaacaagaa cagactcaag
    14881 tacaagatcg catacgaaaa tggaaatggc aatgtcactt ccacataatc aaacacgaat
    14941 cctcatatca acaaggcctg agattctaac tagctcataa caacttagcc aatagttact
    15001 tgagactacc aaatgtatgt agaactaaag actaagggac agagagttcg tctaaacagg
    15061 tgaatctagt cgttgttatc taataaacaa ttcagcccca aatgcagaac acacatagag
    15121 ctctctattg attcaaatta cgatctgata ctgataacgt ctagattttt agggttaaag
    15181 caatcaatca cctgacgatt caaggtggtt ggatcatgac gattccagaa aacatcaagc
    15241 aagctctcaa agctacactc tttgggatca tactgaactc taacaacctc gttatgtccc
    15301 gtagtgccag tacagacatc ctcgtaactc ggattgtgca cgatgccatg gctataccca
    15361 acctcggtct tggtcacacc aggaactctc tggtaagcta gctccactcc ccagaaacaa
    15421 ccggcgccaa attgcgcgaa ttgctgacct gaagacggaa catcatcgtc gggtccttgg
    15481 gcgattgcgg cggaagatgg gtcagcttgg gcttgaggac gagacccgaa tccgagtctg
    15541 ttgaaaaggt tgttcattgg ggatttgtat acggagattg gtcgtcgaga ggtttgaggg
    15601 aaaggacaaa tgggtttggc tctggagaaa gagagtgcgg ctttagagag agaattgaga
    15661 ggtttagaga gagatgcggc ggcgatgagc ggaggagaga cgacgaggac ctgcattatc
    15721 aaagcagtga cgtggtgaaa tttggaactt ttaagaggca gatagattta ttatttgtat
    15781 ccattttctt cattgttcta gaatgtcgcg gaacaaattt taaaactaaa tcctaaattt
    15841 ttctaatttt gttgccaata gtggatatgt gggccgtata gaaggaatct attgaaggcc
    15901 caaacccata ctgacgagcc caaaggttcg ttttgcgttt tatgtttcgg ttcgatgcca
    15961 acgccacatt ctgagctagg caaaaaacaa acgtgtcttt gaatagactc ctctcgttaa
    16021 cacatgcagc ggctgcatgg tgacgccatt aacacgtggc ctacaattgc atgatgtctc
    16081 cattgacacg tgacttctcg tctcctttct taatatatct aacaaacact cctacctctt
    16141 ccaaaatata tacacatctt tttgatcaat ctctcattca aaatctcatt ctctctagta
    16201 aacaagaaca aaaaaatggc ggatacagct agaggaaccc atcacgatat catcggcaga
    16261 gaccagtacc cgatgatggg ccgagaccga gaccagtacc agatgtccgg acgaggatct
    16321 gactactcca agtctaggca gattgctaaa gctgcaactg ctgtcacagc tggtggttcc
    16381 ctccttgttc tctccagcct tacccttgtt ggaactgtca tagctttgac tgttgcaaca
    16441 cctctgctcg ttatcttcag cccaatcctt gtcccggctc tcatcacagt tgcactcctc
    16501 atcaccggtt ttctttcctc tggagggttt ggcattgccg ctataaccgt tttctcttgg
    16561 atttacaagt aagcacacat ttatcatctt acttcataat tttgtgcaat atgtgcatgc
    16621 atgtgttgag ccagtagctt tggatcaatt tttttggtcg aataacaaat gtaacaataa
    16681 gaaattgcaa attctaggga acatttggtt aactaaatac gaaatttgac ctagctagct
    16741 tgaatgtgtc tgtgtatatc atctatatag gtaaaatgct tggtatgata cctattgatt
    16801 gtgaataggt acgcaacggg agagcaccca cagggatcag acaagttgga cagtgcaagg
    16861 atgaagttgg gaagcaaagc tcaggatctg aaagacagag ctcagtacta cggacagcaa
    16921 catactggtg gggaacatga ccgtgaccgt actcgtggtg gccagcacac tactatgagc
    16981 gagctgatta aggagaacat gcacatgaag ctgtacatgg agggcaccgt gaacaaccac
    17041 cacttcaagt gcacatccga gggcgaaggc aagccctacg agggcaccca gaccatgaga
    17101 atcaaggtgg tcgagggcgg ccctctcccc ttcgccttcg acatcctggc taccagcttc
    17161 atgtacggca gcagaacctt catcaaccac acccagggca tccccgactt ctttaagcag
    17221 tccttccctg agggcttcac atgggagaga gtcaccacat acgaagacgg gggcgtgctg
    17281 accgctaccc aggacaccag cctccaggac ggctgcctca tctacaacgt caagatcaga
    17341 ggggtgaact tcccatccaa cggccctgtg atgcagaaga aaacactcgg ctgggaggcc
    17401 aacaccgaga tgctgtaccc cgctgacggc ggcctggaag gcagaagcga catggccctg
    17461 aagctcgtgg gcgggggcca cctgatctgc aacttcaaga ccacatacag atccaagaaa
    17521 cccgctaaga acctcaagat gcccggcgtc tactatgtgg accacagact ggaaagaatc
    17581 aaggaggccg acaaagagac ctacgtcgag cagcacgagg tggctgtggc cagatactgc
    17641 gacctcccta gcaaactggg gcacaagtga tctagtaaca tagatgacac cgcgcgcgat
    17701 aatttatcct agtttgcgcg ctatattttg ttttctatcg cgtattaaat gtataattgc
    17761 gggactctaa tcataaaaac ccatctcata aataacgtca tgcattacat gttaattatt
    17821 acatgcttaa cgtaattcaa cagaaattat atgataatca tcgcaagacc ggcaacagga
    17881 ttcaatctta agaaacttta ttgccaaatg tttgaacgat aagcttggca ctggccgtcg
    17941 ttttacaacg tcgtgactgg gaaaaccctg gcgttaccca acttaatcgc cttgcagcac
    18001 atcccccttt cgccagctgg cgtaatagcg aagaggcccg caccgatcgc ccttcccaac
    18061 agttgcgcag cctgaatggc gaatgagctt gagcttggat cagattgtcg tttcccgcct
    18121 tcagtttaaa ctatcagtgt ttgacaggat atattggcgg gtaaacctaa gagaaaagag
    18181 cgtttattag aataatcgga tatttaaaag ggcgtgaaaa ggtttatccg ttcgtccatt
    18241 tgtatgtgca tgccaaccac agggttcccc tcgggatcaa agtactttaa agtactttaa
    18301 agtactttaa
//
