LOCUS       sequence-331101-       18041 bp    DNA     circular SYN 15-DEC-2025
DEFINITION  Final destination vector for single Gateway LR reaction.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      synthetic DNA construct
  ORGANISM  synthetic DNA construct
REFERENCE   1  (bases 1 to 18041)
  AUTHORS   Ursache R, Fujita S, Denervaud Tendon V, Geldner N
  TITLE     Combined fluorescent seed selection and multiplex CRISPR/Cas9 
            assembly for fast generation of multiple Arabidopsis mutants.
  JOURNAL   Plant Methods. 2021 Oct 30;17(1):111. doi: 
            10.1186/s13007-021-00811-9.
  PUBMED    34717688
REFERENCE   2  (bases 1 to 18041)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Plant 
            Methods."; date: "2021-10-30"; volume: "17(1):111. doi"; pages: " 
            10.1186/s13007-021-00811-9"
COMMENT     Sequence Label: pRU319
FEATURES             Location/Qualifiers
     source          1..18041
                     /mol_type="other DNA"
                     /organism="synthetic DNA construct"
     CDS             1187..1816
                     /codon_start=1
                     /product="stability protein from the Pseudomonas plasmid 
                     pVS1 (Heeb et al., 2000)"
                     /label=pVS1 StaA
                     /translation="MKVIAVLNQKGGSGKTTIATHLARALQLAGADVLLVDSDPQGSAR
                     DWAAVREDQPLTVVGIDRPTIDRDVKAIGRRDFVVIDGAPQAADLAVSAIKAADFVLIP
                     VQPSPYDIWATADLVELVKQRIEVTDGRLQAAFVVSRAIKGTRIGGEVAEALAGYELPI
                     LESRITQRVSYPGTAAAGTTVLESEPEGDAAREVQALAAEIKSKLI"
     CDS             2245..3318
                     /codon_start=1
                     /product="replication protein from the Pseudomonas plasmid 
                     pVS1 (Heeb et al., 2000)"
                     /label=pVS1 RepA
                     /translation="MSGRKPSGPVQIGAALGDDLVEKLKAAQAAQRQRIEAEARPGESW
                     QAAADRIRKESRQPPAAGAPSIRKPPKGDEQPDFFVPMLYDVGTRDSRSIMDVAVFRLS
                     KRDRRAGEVIRYELPDGHVEVSAGPAGMASVWDYDLVLMAVSHLTESMNRYREGKGDKP
                     GRVFRPHVADVLKFCRRADGGKQKDDLVETCIRLNTTHVAMQRTKKAKNGRLVTVSEGE
                     ALISRYKIVKSETGRPEYIEIELADWMYREITEGKNPDVLTVHPDYFLIDPGIGRFLYR
                     LARRAAGKAEARWLFKTIYERSGSAGEFKKFCFTVRKLIGSNDLPEYDLKEEAGQAGPI
                     LVMRYRNLIEGEASAGS"
     rep_origin      3384..3578
                     /label=pVS1 oriV
                     /note="origin of replication for the Pseudomonas plasmid 
                     pVS1 (Heeb et al., 2000)"
     primer_bind     complement(3814..3836)
                     /label=pGEX 3'
                     /note="pGEX vectors, reverse primer"
     misc_feature    3922..4062
                     /label=bom
                     /note="basis of mobility region from pBR322"
     primer_bind     3977..3996
                     /label=pRS-marker
                     /note="pRS vectors, use to sequence yeast selectable 
                     marker"
     primer_bind     complement(4077..4094)
                     /label=L4440
                     /note="L4440 vector, forward primer"
     rep_origin      complement(4248..4836)
                     /direction=LEFT
                     /label=ori
                     /note="high-copy-number ColE1/pMB1/pBR322/pUC origin of 
                     replication"
     primer_bind     complement(4328..4347)
                     /label=pBR322ori-F
                     /note="pBR322 origin, forward primer"
     CDS             complement(5082..5873)
                     /codon_start=1
                     /gene="aadA"
                     /product="aminoglycoside adenylyltransferase (Murphy, 
                     1985)"
                     /label=SmR
                     /note="confers resistance to spectinomycin and 
                     streptomycin"
                     /translation="MGEAVIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKPH
                     SDIDLLVTVTVRLDETTRRALINDLLETSASPGESEILRAVEVTIVVHDDIIPWRYPAK
                     RELQFGEWQRNDILAGIFEPATIDIDLAILLTKAREHSVALVGPAAEELFDPVPEQDLF
                     EALNETLTLWNSPPDWAGDERNVVLTLSRIWYSAVTGKIAPKDVAADWAMERLPAQYQP
                     VILEARQAYLGQEEDRLASRADQLEEFVHYVKGEITKVVGK"
     misc_feature    6394..6418
                     /label=LB T-DNA repeat
                     /note="left border repeat from nopaline C58 T-DNA"
     protein_bind    6595..6616
                     /label=CAP binding site
                     /bound_moiety="E. coli catabolite activator protein"
                     /note="CAP binding activates transcription in the presence 
                     of cAMP."
     promoter        join(6631..6636,6637..6654,6655..6661)
                     /label=lac promoter
                     /note="promoter for the E. coli lac operon"
     protein_bind    6669..6685
                     /label=lac operator
                     /bound_moiety="lac repressor encoded by lacI"
                     /note="The lac repressor binds to the lac operator to 
                     inhibit transcription in E. coli. This inhibition can be 
                     relieved by adding lactose or 
                     isopropyl-beta-D-thiogalactopyranoside (IPTG)."
     primer_bind     6674..6696
                     /label=M13/pUC Reverse
                     /note="In lacZ gene"
     primer_bind     6693..6709
                     /label=M13 rev
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     primer_bind     6693..6709
                     /label=M13 Reverse
                     /note="In lacZ gene. Also called M13-rev"
     CDS             8101..12204
                     /codon_start=1
                     /product="Cas9 (Csn1) endonuclease from the Streptococcus 
                     pyogenes Type II CRISPR/Cas system"
                     /label=Cas9
                     /note="generates RNA-guided double strand breaks in DNA"
                     /translation="MDKKYSIGLDIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKK
                     NLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEES
                     FLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIK
                     FRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRL
                     ENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQ
                     IGDQYADLFLAAKNLSDAILLSDILRVNTEITKAPLSASMIKRYDEHHQDLTLLKALVR
                     QQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLL
                     RKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARG
                     NSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEY
                     FTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFD
                     SVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEER
                     LKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFM
                     QLIHDDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGR
                     HKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLY
                     LYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVP
                     SEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKH
                     VAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYL
                     NAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIGKATAKYFFYSNIMNFFKT
                     EITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSK
                     ESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGI
                     TIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNE
                     LALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILAD
                     ANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVL
                     DATLIHQSITGLYETRIDLSQLGGD"
     CDS             8101..12204
                     /codon_start=1
                     /product="Cas9 (Csn1) endonuclease from the Streptococcus 
                     pyogenes Type II CRISPR/Cas system"
                     /label=Cas9
                     /note="generates RNA-guided double strand breaks in DNA"
                     /translation="MDKKYSIGLDIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKK
                     NLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEES
                     FLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIK
                     FRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRL
                     ENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQ
                     IGDQYADLFLAAKNLSDAILLSDILRVNTEITKAPLSASMIKRYDEHHQDLTLLKALVR
                     QQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLL
                     RKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARG
                     NSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEY
                     FTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFD
                     SVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEER
                     LKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFM
                     QLIHDDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGR
                     HKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLY
                     LYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVP
                     SEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKH
                     VAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYL
                     NAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIGKATAKYFFYSNIMNFFKT
                     EITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSK
                     ESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGI
                     TIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNE
                     LALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILAD
                     ANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVL
                     DATLIHQSITGLYETRIDLSQLGGD"
     CDS             12217..12237
                     /codon_start=1
                     /product="nuclear localization signal of SV40 (simian virus
                     40) large T antigen"
                     /label=SV40 NLS
                     /translation="PKKKRKV"
     protein_bind    12749..12873
                     /gene="mutant version of attR"
                     /label=attR1
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
     promoter        join(12898..12903,12904..12921,12922..12928)
                     /label=lac UV5 promoter
                     /note="E. coli lac promoter with an ""up"" mutation"
     CDS             12982..13662
                     /codon_start=1
                     /product="chloramphenicol acetyltransferase"
                     /label=CmR
                     /note="confers resistance to chloramphenicol"
                     /translation="MEKKITGYTTVDISQWHRKEHFEAFQSVAQCTYNQTVQLDITAFL
                     KTVKKNKHKFYPAFIHILARLMNAHPEFRMAMKDGELVIWDSVHPCYTVFHEQTETFSS
                     LWSEYHDDFRQFLHIYSQDVACYGENLAYFPKGFIENMFFVSANPWVSFTSFDLNVANM
                     DNFFAPVFTMGKYYTQGDKVLMPLAIQVHHAVCDGFHVGRMLNELQQYCDEWQAGRNLE
                     DPAY"
     primer_bind     complement(13048..13067)
                     /label=CAT-R
                     /note="Chloramphenicol resistance gene, reverse primer"
     CDS             13982..14287
                     /codon_start=1
                     /gene="ccdB"
                     /product="CcdB, a bacterial toxin that poisons DNA gyrase"
                     /label=ccdB
                     /note="Plasmids containing the ccdB gene cannot be 
                     propagated in standard E. coli strains."
                     /translation="MQFKVYTYKRESRYRLFVDVQSDIIDTPGRRMVIPLASARLLSDK
                     VPRELYPVVHIGDESWRMMTTDMASVPVSVIGEEVADLSHRENDIKNAINLMFWGI"
     primer_bind     14166..14185
                     /label=ccdB-fwd
                     /note="ccdB gene, forward primer"
     protein_bind    complement(14328..14452)
                     /gene="mutant version of attR"
                     /label=attR2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
     CDS             16706..17401
                     /codon_start=1
                     /product="monomeric far-red fluorescent protein (Shcherbo 
                     et al., 2009)"
                     /label=mKate2
                     /note="mammalian codon-optimized"
                     /translation="MSELIKENMHMKLYMEGTVNNHHFKCTSEGEGKPYEGTQTMRIKV
                     VEGGPLPFAFDILATSFMYGSRTFINHTQGIPDFFKQSFPEGFTWERVTTYEDGGVLTA
                     TQDTSLQDGCLIYNVKIRGVNFPSNGPVMQKKTLGWEANTEMLYPADGGLEGRSDMALK
                     LVGGGHLICNFKTTYRSKKPAKNLKMPGVYYVDHRLERIKEADKETYVEQHEVAVARYC
                     DLPSKLGHK"
     terminator      complement(17400..17651)
                     /label=NOS terminator
                     /note="nopaline synthase terminator and poly(A) signal"
     primer_bind     complement(17661..17678)
                     /label=M13 Forward
                     /note="In lacZ gene. Also called M13-F20 or M13 (-21) 
                     Forward"
     primer_bind     complement(17661..17677)
                     /label=M13 fwd
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     primer_bind     complement(17670..17692)
                     /label=M13/pUC Forward
                     /note="In lacZ gene"
     misc_feature    17873..17897
                     /label=RB T-DNA repeat
                     /note="right border repeat from nopaline C58 T-DNA"
ORIGIN
        1 agtactttga tccaacccct ccgctgctat agtgcagtcg gcttctgacg ttcagtgcag
       61 ccgtcttctg aaaacgacat gtcgcacaag tcctaagtta cgcgacaggc tgccgccctg
      121 cccttttcct ggcgttttct tgtcgcgtgt tttagtcgca taaagtagaa tacttgcgac
      181 tagaaccgga gacattacgc catgaacaag agcgccgccg ctggcctgct gggctatgcc
      241 cgcgtcagca ccgacgacca ggacttgacc aaccaacggg ccgaactgca cgcggccggc
      301 tgcaccaagc tgttttccga gaagatcacc ggcaccaggc gcgaccgccc ggagctggcc
      361 aggatgcttg accacctacg ccctggcgac gttgtgacag tgaccaggct agaccgcctg
      421 gcccgcagca cccgcgacct actggacatt gccgagcgca tccaggaggc cggcgcgggc
      481 ctgcgtagcc tggcagagcc gtgggccgac accaccacgc cggccggccg catggtgttg
      541 accgtgttcg ccggcattgc cgagttcgag cgttccctaa tcatcgaccg cacccggagc
      601 gggcgcgagg ccgccaaggc ccgaggcgtg aagtttggcc cccgccctac cctcaccccg
      661 gcacagatcg cgcacgcccg cgagctgatc gaccaggaag gccgcaccgt gaaagaggcg
      721 gctgcactgc ttggcgtgca tcgctcgacc ctgtaccgcg cacttgagcg cagcgaggaa
      781 gtgacgccca ccgaggccag gcggcgcggt gccttccgtg aggacgcatt gaccgaggcc
      841 gacgccctgg cggccgccga gaatgaacgc caagaggaac aagcatgaaa ccgcaccagg
      901 acggccagga cgaaccgttt ttcattaccg aagagatcga ggcggagatg atcgcggccg
      961 ggtacgtgtt cgagccgccc gcgcacgtct caaccgtgcg gctgcatgaa atcctggccg
     1021 gtttgtctga tgccaagctg gcggcctggc cggccagctt ggccgctgaa gaaaccgagc
     1081 gccgccgtct aaaaaggtga tgtgtatttg agtaaaacag cttgcgtcat gcggtcgctg
     1141 cgtatatgat gcgatgagta aataaacaaa tacgcaaggg gaacgcatga aggttatcgc
     1201 tgtacttaac cagaaaggcg ggtcaggcaa gacgaccatc gcaacccatc tagcccgcgc
     1261 cctgcaactc gccggggccg atgttctgtt agtcgattcc gatccccagg gcagtgcccg
     1321 cgattgggcg gccgtgcggg aagatcaacc gctaaccgtt gtcggcatcg accgcccgac
     1381 gattgaccgc gacgtgaagg ccatcggccg gcgcgacttc gtagtgatcg acggagcgcc
     1441 ccaggcggcg gacttggctg tgtccgcgat caaggcagcc gacttcgtgc tgattccggt
     1501 gcagccaagc ccttacgaca tatgggccac cgccgacctg gtggagctgg ttaagcagcg
     1561 cattgaggtc acggatggaa ggctacaagc ggcctttgtc gtgtcgcggg cgatcaaagg
     1621 cacgcgcatc ggcggtgagg ttgccgaggc gctggccggg tacgagctgc ccattcttga
     1681 gtcccgtatc acgcagcgcg tgagctaccc aggcactgcc gccgccggca caaccgttct
     1741 tgaatcagaa cccgagggcg acgctgcccg cgaggtccag gcgctggccg ctgaaattaa
     1801 atcaaaactc atttgagtta atgaggtaaa gagaaaatga gcaaaagcac aaacacgcta
     1861 agtgccggcc gtccgagcgc acgcagcagc aaggctgcaa cgttggccag cctggcagac
     1921 acgccagcca tgaagcgggt caactttcag ttgccggcgg aggatcacac caagctgaag
     1981 atgtacgcgg tacgccaagg caagaccatt accgagctgc tatctgaata catcgcgcag
     2041 ctaccagagt aaatgagcaa atgaataaat gagtagatga attttagcgg ctaaaggagg
     2101 cggcatggaa aatcaagaac aaccaggcac cgacgccgtg gaatgcccca tgtgtggagg
     2161 aacgggcggt tggccaggcg taagcggctg ggttgtctgc cggccctgca atggcactgg
     2221 aacccccaag cccgaggaat cggcgtgagc ggtcgcaaac catccggccc ggtacaaatc
     2281 ggcgcggcgc tgggtgatga cctggtggag aagttgaagg ccgcgcaggc cgcccagcgg
     2341 caacgcatcg aggcagaagc acgccccggt gaatcgtggc aagcggccgc tgatcgaatc
     2401 cgcaaagaat cccggcaacc gccggcagcc ggtgcgccgt cgattaggaa gccgcccaag
     2461 ggcgacgagc aaccagattt tttcgttccg atgctctatg acgtgggcac ccgcgatagt
     2521 cgcagcatca tggacgtggc cgttttccgt ctgtcgaagc gtgaccgacg agctggcgag
     2581 gtgatccgct acgagcttcc agacgggcac gtagaggttt ccgcagggcc ggccggcatg
     2641 gccagtgtgt gggattacga cctggtactg atggcggttt cccatctaac cgaatccatg
     2701 aaccgatacc gggaagggaa gggagacaag cccggccgcg tgttccgtcc acacgttgcg
     2761 gacgtactca agttctgccg gcgagccgat ggcggaaagc agaaagacga cctggtagaa
     2821 acctgcattc ggttaaacac cacgcacgtt gccatgcagc gtacgaagaa ggccaagaac
     2881 ggccgcctgg tgacggtatc cgagggtgaa gccttgatta gccgctacaa gatcgtaaag
     2941 agcgaaaccg ggcggccgga gtacatcgag atcgagctag ctgattggat gtaccgcgag
     3001 atcacagaag gcaagaaccc ggacgtgctg acggttcacc ccgattactt tttgatcgat
     3061 cccggcatcg gccgttttct ctaccgcctg gcacgccgcg ccgcaggcaa ggcagaagcc
     3121 agatggttgt tcaagacgat ctacgaacgc agtggcagcg ccggagagtt caagaagttc
     3181 tgtttcaccg tgcgcaagct gatcgggtca aatgacctgc cggagtacga tttgaaggag
     3241 gaggcggggc aggctggccc gatcctagtc atgcgctacc gcaacctgat cgagggcgaa
     3301 gcatccgccg gttcctaatg tacggagcag atgctagggc aaattgccct agcaggggaa
     3361 aaaggtcgaa aaggtctctt tcctgtggat agcacgtaca ttgggaaccc aaagccgtac
     3421 attgggaacc ggaacccgta cattgggaac ccaaagccgt acattgggaa ccggtcacac
     3481 atgtaagtga ctgatataaa agagaaaaaa ggcgattttt ccgcctaaaa ctctttaaaa
     3541 cttattaaaa ctcttaaaac ccgcctggcc tgtgcataac tgtctggcca gcgcacagcc
     3601 gaagagctgc aaaaagcgcc tacccttcgg tcgctgcgct ccctacgccc cgccgcttcg
     3661 cgtcggccta tcgcggccgc tggccgctca aaaatggctg gcctacggcc aggcaatcta
     3721 ccagggcgcg gacaagccgc gccgtcgcca ctcgaccgcc ggcgcccaca tcaaggcacc
     3781 ctgcctcgcg cgtttcggtg atgacggtga aaacctctga cacatgcagc tcccggagac
     3841 ggtcacagct tgtctgtaag cggatgccgg gagcagacaa gcccgtcagg gcgcgtcagc
     3901 gggtgttggc gggtgtcggg gcgcagccat gacccagtca cgtagcgata gcggagtgta
     3961 tactggctta actatgcggc atcagagcag attgtactga gagtgcacca tatgcggtgt
     4021 gaaataccgc acagatgcgt aaggagaaaa taccgcatca ggcgctcttc cgcttcctcg
     4081 ctcactgact cgctgcgctc ggtcgttcgg ctgcggcgag cggtatcagc tcactcaaag
     4141 gcggtaatac ggttatccac agaatcaggg gataacgcag gaaagaacat gtgagcaaaa
     4201 ggccagcaaa aggccaggaa ccgtaaaaag gccgcgttgc tggcgttttt ccataggctc
     4261 cgcccccctg acgagcatca caaaaatcga cgctcaagtc agaggtggcg aaacccgaca
     4321 ggactataaa gataccaggc gtttccccct ggaagctccc tcgtgcgctc tcctgttccg
     4381 accctgccgc ttaccggata cctgtccgcc tttctccctt cgggaagcgt ggcgctttct
     4441 catagctcac gctgtaggta tctcagttcg gtgtaggtcg ttcgctccaa gctgggctgt
     4501 gtgcacgaac cccccgttca gcccgaccgc tgcgccttat ccggtaacta tcgtcttgag
     4561 tccaacccgg taagacacga cttatcgcca ctggcagcag ccactggtaa caggattagc
     4621 agagcgaggt atgtaggcgg tgctacagag ttcttgaagt ggtggcctaa ctacggctac
     4681 actagaagga cagtatttgg tatctgcgct ctgctgaagc cagttacctt cggaaaaaga
     4741 gttggtagct cttgatccgg caaacaaacc accgctggta gcggtggttt ttttgtttgc
     4801 aagcagcaga ttacgcgcag aaaaaaagga tctcaagaag atcctttgat cttttctacg
     4861 gggtctgacg ctcagtggaa cgaaaactca cgttaaggga ttttggtcat gcatgatata
     4921 tctcccaatt tgtgtagggc ttattatgca cgcttaaaaa taataaaagc agacttgacc
     4981 tgatagtttg gctgtgagca attatgtgct tagtgcatct aacgcttgag ttaagccgcg
     5041 ccgcgaagcg gcgtcggctt gaacgaattt ctagctagac attatttgcc gactaccttg
     5101 gtgatctcgc ctttcacgta gtggacaaat tcttccaact gatctgcgcg cgaggccaag
     5161 cgatcttctt cttgtccaag ataagcctgt ctagcttcaa gtatgacggg ctgatactgg
     5221 gccggcaggc gctccattgc ccagtcggca gcgacatcct tcggcgcgat tttgccggtt
     5281 actgcgctgt accaaatgcg ggacaacgta agcactacat ttcgctcatc gccagcccag
     5341 tcgggcggcg agttccatag cgttaaggtt tcatttagcg cctcaaatag atcctgttca
     5401 ggaaccggat caaagagttc ctccgccgct ggacctacca aggcaacgct atgttctctt
     5461 gcttttgtca gcaagatagc cagatcaatg tcgatcgtgg ctggctcgaa gatacctgca
     5521 agaatgtcat tgcgctgcca ttctccaaat tgcagttcgc gcttagctgg ataacgccac
     5581 ggaatgatgt cgtcgtgcac aacaatggtg acttctacag cgcggagaat ctcgctctct
     5641 ccaggggaag ccgaagtttc caaaaggtcg ttgatcaaag ctcgccgcgt tgtttcatca
     5701 agccttacgg tcaccgtaac cagcaaatca atatcactgt gtggcttcag gccgccatcc
     5761 actgcggagc cgtacaaatg tacggccagc aacgtcggtt cgagatggcg ctcgatgacg
     5821 ccaactacct ctgatagttg agtcgatact tcggcgatca ccgcttcccc catgatgttt
     5881 aactttgttt tagggcgact gccctgctgc gtaacatcgt tgctgctcca taacatcaaa
     5941 catcgaccca cggcgtaacg cgcttgctgc ttggatgccc gaggcataga ctgtacccca
     6001 aaaaaacagt cataacaagc catgaaaacc gccactgcgc cgttaccacc gctgcgttcg
     6061 gtcaaggttc tggaccagtt gcgtgagcgc atacgctact tgcattacag cttacgaacc
     6121 gaacaggctt atgtccactg ggttcgtgcc cgaattgatc acaggcagca acgctctgtc
     6181 atcgttacaa tcaacatgct accctccgcg agatcatccg tgtttcaaac ccggcagctt
     6241 agttgccgtt cttccgaata gcatcggtaa catgagcaaa gtctgccgcc ttacaacggc
     6301 tctcccgctg acgccgtccc ggactgatgg gctgcctgta tcgagtggtg attttgtgcc
     6361 gagctgccgg tcggggagct gttggctggc tggtggcagg atatattgtg gtgtaaacaa
     6421 attgacgctt agacaactta ataacacatt gcggacgttt ttaatgtact gaattaacgc
     6481 cgaattgctc tagccaatac gcaaaccgcc tctccccgcg cgttggccga ttcattaatg
     6541 cagctggcac gacaggtttc ccgactggaa agcgggcagt gagcgcaacg caattaatgt
     6601 gagttagctc actcattagg caccccaggc tttacacttt atgcttccgg ctcgtatgtt
     6661 gtgtggaatt gtgagcggat aacaatttca cacaggaaac agctatgaca tgattacgaa
     6721 ttcggtaccg aataaaagca tttgcgtttg gtttatcatt gcgtttatac aaggacagag
     6781 atccactgag ctggaatagc ttaaaaccat tatcagaaca aaataaacca ttttttgtta
     6841 agaatcagag catagtaaac aacagaaaca acctaagaga ggtaacttgt ccaagaagat
     6901 agctaattat atctatttta taaaagttat catagtttgt aagtcacaaa agatgcaaat
     6961 aacagagaaa ctaggagact tgagaatata cattcttgta tatttgtatt cgagattgtg
     7021 aaaatttgac cataagttta aattcttaaa aagatatatc tgatctaggt gatggttata
     7081 gactgtaatt ttaccacatg tttaatgatg gatagtgaca cacatgacac atcgacaaca
     7141 ctatagcatc ttatttagat tacaacatga aatttttctg taatacatgt ctttgtacat
     7201 aatttaaaag taattcctaa gaaatatatt tatacaagga gtttaaagaa aacatagcat
     7261 aaagttcaat gagtagtaaa aaccatatac agtatatagc ataaagttca atgagtttat
     7321 tacaaaagca ttggttcact ttctgtaaca cgacgttaaa ccttcgtctc caataggagc
     7381 gctactgatt caacatgcca atatatacta aatacgtttc tacagtcaaa tgctttaacg
     7441 tttcatgatt aagtgactat ttaccgtcaa tcctttccca ttcctcccac taatccaact
     7501 ttttaattac tcttaaatca ccactaagct agtaacgcct atcatgaatt agctctacta
     7561 aatctagcaa cctttcaaat ttgcagtatt gcaggtgtct ctgtgtcttt aaaatagttg
     7621 ccttatgatt tcttcggttt caagatgatc aaatagttat agatttcatg ctcacacatg
     7681 ctcattagat gtgtacatac tttacttacc caaatctatt ttctcgcaaa gattttgatg
     7741 gtaaagctga tttggttcta ttgaactaaa tcaaacgagt ttcagactga gtgattctaa
     7801 tccggcccat tagcccctaa acagacccac taattacgca gcttttaata gagtaattac
     7861 acctagttta cccactaaac cactaagcac taattatctc acaatctaat gagcttccct
     7921 cgtaattact tgggctttca ctctaccatt tatttgtaac agtcaagtct ctactgtctc
     7981 tatataaact ctctaaagtt aacacacaat tctcatcaca aacaaatcaa ccaaagcaac
     8041 ttctactctt tcttctttcg accttatcaa tctgttgaga aggtaccaat tcggcgcgcc
     8101 atggataaga agtactctat cggactcgat atcggaacta actctgtggg atgggctgtg
     8161 atcaccgatg agtacaaggt gccatctaag aagttcaagg ttctcggaaa caccgatagg
     8221 cactctatca agaaaaacct tatcggtgct ctcctcttcg attctggtga aactgctgag
     8281 gctaccagac tcaagagaac cgctagaaga aggtacacca gaagaaagaa caggatctgc
     8341 tacctccaag agatcttctc taacgagatg gctaaagtgg atgattcatt cttccacagg
     8401 ctcgaagagt cattcctcgt ggaagaagat aagaagcacg agaggcaccc tatcttcgga
     8461 aacatcgttg atgaggtggc ataccacgag aagtacccta ctatctacca cctcagaaag
     8521 aagctcgttg attctactga taaggctgat ctcaggctca tctacctcgc tctcgctcac
     8581 atgatcaagt tcagaggaca cttcctcatc gagggtgatc tcaaccctga taactctgat
     8641 gtggataagt tgttcatcca gctcgtgcag acctacaacc agcttttcga agagaaccct
     8701 atcaacgctt caggtgtgga tgctaaggct atcctctctg ctaggctctc taagtcaaga
     8761 aggcttgaga acctcattgc tcagctccct ggtgagaaga agaacggact tttcggaaac
     8821 ttgatcgctc tctctctcgg actcacccct aacttcaagt ctaacttcga tctcgctgag
     8881 gatgcaaagc tccagctctc aaaggatacc tacgatgatg atctcgataa cctcctcgct
     8941 cagatcggag atcagtacgc tgatttgttc ctcgctgcta agaacctctc tgatgctatc
     9001 ctcctcagtg atatcctcag agtgaacacc gagatcacca aggctccact ctcagcttct
     9061 atgatcaaga gatacgatga gcaccaccag gatctcacac ttctcaaggc tcttgttaga
     9121 cagcagctcc cagagaagta caaagagatt ttcttcgatc agtctaagaa cggatacgct
     9181 ggttacatcg atggtggtgc atctcaagaa gagttctaca agttcatcaa gcctatcctc
     9241 gagaagatgg atggaaccga ggaactcctc gtgaagctca atagagagga tcttctcaga
     9301 aagcagagga ccttcgataa cggatctatc cctcatcaga tccacctcgg agagttgcac
     9361 gctatcctta gaaggcaaga ggatttctac ccattcctca aggataacag ggaaaagatt
     9421 gagaagattc tcaccttcag aatcccttac tacgtgggac ctctcgctag aggaaactca
     9481 agattcgctt ggatgaccag aaagtctgag gaaaccatca ccccttggaa cttcgaagag
     9541 gtggtggata agggtgctag tgctcagtct ttcatcgaga ggatgaccaa cttcgataag
     9601 aaccttccaa acgagaaggt gctccctaag cactctttgc tctacgagta cttcaccgtg
     9661 tacaacgagt tgaccaaggt taagtacgtg accgagggaa tgaggaagcc tgcttttttg
     9721 tcaggtgagc aaaagaaggc tatcgttgat ctcttgttca agaccaacag aaaggtgacc
     9781 gtgaagcagc tcaaagagga ttacttcaag aaaatcgagt gcttcgattc agttgagatt
     9841 tctggtgttg aggataggtt caacgcatct ctcggaacct accacgatct cctcaagatc
     9901 attaaggata aggatttctt ggataacgag gaaaacgagg atatcttgga ggatatcgtt
     9961 cttaccctca ccctctttga agatagagag atgattgaag aaaggctcaa gacctacgct
    10021 catctcttcg atgataaggt gatgaagcag ttgaagagaa gaagatacac tggttgggga
    10081 aggctctcaa gaaagctcat taacggaatc agggataagc agtctggaaa gacaatcctt
    10141 gatttcctca agtctgatgg attcgctaac agaaacttca tgcagctcat ccacgatgat
    10201 tctctcacct ttaaagagga tatccagaag gctcaggttt caggacaggg tgatagtctc
    10261 catgagcata tcgctaacct cgctggatct cctgcaatca agaagggaat cctccagact
    10321 gtgaaggttg tggatgagtt ggtgaaggtg atgggaaggc ataagcctga gaacatcgtg
    10381 atcgaaatgg ctagagagaa ccagaccact cagaagggac agaagaactc tagggaaagg
    10441 atgaagagga tcgaggaagg tatcaaagag cttggatctc agatcctcaa agagcaccct
    10501 gttgagaaca ctcagctcca gaatgagaag ctctacctct actacctcca gaacggaagg
    10561 gatatgtatg tggatcaaga gttggatatc aacaggctct ctgattacga tgttgatcat
    10621 atcgtgccac agtcattctt gaaggatgat tctatcgata acaaggtgct caccaggtct
    10681 gataagaaca ggggtaagag tgataacgtg ccaagtgaag aggttgtgaa gaaaatgaag
    10741 aactattgga ggcagctcct caacgctaag ctcatcactc agagaaagtt cgataacttg
    10801 actaaggctg agaggggagg actctctgaa ttggataagg caggattcat caagaggcag
    10861 cttgtggaaa ccaggcagat cactaagcac gttgcacaga tcctcgattc taggatgaac
    10921 accaagtacg atgagaacga taagttgatc agggaagtga aggttatcac cctcaagtca
    10981 aagctcgtgt ctgatttcag aaaggatttc caattctaca aggtgaggga aatcaacaac
    11041 taccaccacg ctcacgatgc ttaccttaac gctgttgttg gaaccgctct catcaagaag
    11101 tatcctaagc tcgagtcaga gttcgtgtac ggtgattaca aggtgtacga tgtgaggaag
    11161 atgatcgcta agtctgagca agagatcgga aaggctaccg ctaagtattt cttctactct
    11221 aacatcatga atttcttcaa gaccgagatt accctcgcta acggtgagat cagaaagagg
    11281 ccactcatcg agacaaacgg tgaaacaggt gagatcgtgt gggataaggg aagggatttc
    11341 gctaccgtta gaaaggtgct ctctatgcca caggtgaaca tcgttaagaa aaccgaggtg
    11401 cagaccggtg gattctctaa agagtctatc ctccctaaga ggaactctga taagctcatt
    11461 gctaggaaga aggattggga ccctaagaaa tacggtggtt tcgattctcc taccgtggct
    11521 tactctgttc tcgttgtggc taaggttgag aagggaaaga gtaagaagct caagtctgtt
    11581 aaggaacttc tcggaatcac tatcatggaa aggtcatctt tcgagaagaa cccaatcgat
    11641 ttcctcgagg ctaagggata caaagaggtt aagaaggatc tcatcatcaa gctcccaaag
    11701 tactcactct tcgaactcga gaacggtaga aagaggatgc tcgcttctgc tggtgagctt
    11761 caaaagggaa acgagcttgc tctcccatct aagtacgtta actttcttta cctcgcttct
    11821 cactacgaga agttgaaggg atctccagaa gataacgagc agaagcaact tttcgttgag
    11881 cagcacaagc actacttgga tgagatcatc gagcagatct ctgagttctc taaaagggtg
    11941 atcctcgctg atgcaaacct cgataaggtg ttgtctgctt acaacaagca cagagataag
    12001 cctatcaggg aacaggcaga gaacatcatc catctcttca cccttaccaa cctcggtgct
    12061 cctgctgctt tcaagtactt cgatacaacc atcgatagga agagatacac ctctaccaaa
    12121 gaagtgctcg atgctaccct catccatcag tctatcactg gactctacga gactaggatc
    12181 gatctctcac agctcggtgg tgattcaagg gctgatccta agaagaagag gaaggtttga
    12241 ggcgcgccga gctccaggcc tcccagcttt cgtccgtatc atcggtttcg acaacgttcg
    12301 tcaagttcaa tgcatcagtt tcattgccca cacaccagaa tcctactaag tttgagtatt
    12361 atggcattgg aaaagctgtt ttcttctatc atttgttctg cttgtaattt actgtgttct
    12421 ttcagttttt gttttcggac atcaaaatgc aaatggatgg ataagagtta ataaatgata
    12481 tggtcctttt gttcattctc aaattattat tatctgttgt ttttacttta atgggttgaa
    12541 tttaagtaag aaaggaacta acagtgtgat attaaggtgc aatgttagac atataaaaca
    12601 gtctttcacc tctctttggt tatgtcttga attggtttgt ttcttcactt atctgtgtaa
    12661 tcaagtttac tatgagtcta tgatcaagta attatgcaat caagttaagt acagtatagg
    12721 cttgagctcc ctaggcctgt tatccctaac aagtttgtac aaaaaagctg aacgagaaac
    12781 gtaaaatgat ataaatatca atatattaaa ttagattttg cataaaaaac agactacata
    12841 atactgtaaa acacaacata tccagtcact atggcggccg cattaggcac cccaggcttt
    12901 acactttatg cttccggctc gtataatgtg tggattttga gttaggatcc gtcgagattt
    12961 tcaggagcta aggaagctaa aatggagaaa aaaatcactg gatataccac cgttgatata
    13021 tcccaatggc atcgtaaaga acattttgag gcatttcagt cagttgctca atgtacctat
    13081 aaccagaccg ttcagctgga tattacggcc tttttaaaga ccgtaaagaa aaataagcac
    13141 aagttttatc cggcctttat tcacattctt gcccgcctga tgaatgctca tccggaattc
    13201 cgtatggcaa tgaaagacgg tgagctggtg atatgggata gtgttcaccc ttgttacacc
    13261 gttttccatg agcaaactga aacgttttca tcgctctgga gtgaatacca cgacgatttc
    13321 cggcagtttc tacacatata ttcgcaagat gtggcgtgtt acggtgaaaa cctggcctat
    13381 ttccctaaag ggtttattga gaatatgttt ttcgtctcag ccaatccctg ggtgagtttc
    13441 accagttttg atttaaacgt ggccaatatg gacaacttct tcgcccccgt tttcaccatg
    13501 ggcaaatatt atacgcaagg cgacaaggtg ctgatgccgc tggcgattca ggttcatcat
    13561 gccgtttgtg atggcttcca tgtcggcaga atgcttaatg aattacaaca gtactgcgat
    13621 gagtggcagg cggggcgtaa tctagaggat ccggcttact aaaagccaga taacagtatg
    13681 cgtatttgcg cgctgatttt tgcggtataa gaatatatac tgatatgtat acccgaagta
    13741 tgtcaaaaag aggtatgcta tgaagcagcg tattacagtg acagttgaca gcgacagcta
    13801 tcagttgctc aaggcatata tgatgtcaat atctccggtc tggtaagcac aaccatgcag
    13861 aatgaagccc gtcgtctgcg tgccgaacgc tggaaagcgg aaaatcagga agggatggct
    13921 gaggtcgccc ggtttattga aatgaacggc tcttttgctg acgagaacag gggctggtga
    13981 aatgcagttt aaggtttaca cctataaaag agagagccgt tatcgtctgt ttgtggatgt
    14041 acagagtgat attattgaca cgcccgggcg acggatggtg atccccctgg ccagtgcacg
    14101 tctgctgtca gataaagtcc cccgtgaact ttacccggtg gtgcatatcg gggatgaaag
    14161 ctggcgcatg atgaccaccg atatggccag tgtgccggtc tccgttatcg gggaagaagt
    14221 ggctgatctc agccaccgcg aaaatgacat caaaaacgcc attaacctga tgttctgggg
    14281 aatataaatg tcaggctccc ttatacacag ccagtctgca ggtcgaccat agtgactgga
    14341 tatgttgtgt tttacagtat tatgtagtct gttttttatg caaaatctaa tttaatatat
    14401 tgatatttat atcattttac gtttctcgtt cagctttctt gtacaaagtg gttcgataat
    14461 tccgatccag cctaggcccg ggcctgagga cgcgtccatg gttaattaag acgtccggac
    14521 cgactagtgg atcctctaga gtcgacctgc aggcatgcaa gcttcttcaa gtgtatgtag
    14581 gtatagtaac atgaacaaga acagactcaa gtacaagatc gcatacgaaa atggaaatgg
    14641 caatgtcact tccacataat caaacacgaa tcctcatatc aacaaggcct gagattctaa
    14701 ctagctcata acaacttagc caatagttac ttgagactac caaatgtatg tagaactaaa
    14761 gactaaggga cagagagttc gtctaaacag gtgaatctag tcgttgttat ctaataaaca
    14821 attcagcccc aaatgcagaa cacacataga gctctctatt gattcaaatt acgatctgat
    14881 actgataacg tctagatttt tagggttaaa gcaatcaatc acctgacgat tcaaggtggt
    14941 tggatcatga cgattccaga aaacatcaag caagctctca aagctacact ctttgggatc
    15001 atactgaact ctaacaacct cgttatgtcc cgtagtgcca gtacagacat cctcgtaact
    15061 cggattgtgc acgatgccat ggctataccc aacctcggtc ttggtcacac caggaactct
    15121 ctggtaagct agctccactc cccagaaaca accggcgcca aattgcgcga attgctgacc
    15181 tgaagacgga acatcatcgt cgggtccttg ggcgattgcg gcggaagatg ggtcagcttg
    15241 ggcttgagga cgagacccga atccgagtct gttgaaaagg ttgttcattg gggatttgta
    15301 tacggagatt ggtcgtcgag aggtttgagg gaaaggacaa atgggtttgg ctctggagaa
    15361 agagagtgcg gctttagaga gagaattgag aggtttagag agagatgcgg cggcgatgag
    15421 cggaggagag acgacgagga cctgcattat caaagcagtg acgtggtgaa atttggaact
    15481 tttaagaggc agatagattt attatttgta tccattttct tcattgttct agaatgtcgc
    15541 ggaacaaatt ttaaaactaa atcctaaatt tttctaattt tgttgccaat agtggatatg
    15601 tgggccgtat agaaggaatc tattgaaggc ccaaacccat actgacgagc ccaaaggttc
    15661 gttttgcgtt ttatgtttcg gttcgatgcc aacgccacat tctgagctag gcaaaaaaca
    15721 aacgtgtctt tgaatagact cctctcgtta acacatgcag cggctgcatg gtgacgccat
    15781 taacacgtgg cctacaattg catgatgtct ccattgacac gtgacttctc gtctcctttc
    15841 ttaatatatc taacaaacac tcctacctct tccaaaatat atacacatct ttttgatcaa
    15901 tctctcattc aaaatctcat tctctctagt aaacaagaac aaaaaaatgg cggatacagc
    15961 tagaggaacc catcacgata tcatcggcag agaccagtac ccgatgatgg gccgagaccg
    16021 agaccagtac cagatgtccg gacgaggatc tgactactcc aagtctaggc agattgctaa
    16081 agctgcaact gctgtcacag ctggtggttc cctccttgtt ctctccagcc ttacccttgt
    16141 tggaactgtc atagctttga ctgttgcaac acctctgctc gttatcttca gcccaatcct
    16201 tgtcccggct ctcatcacag ttgcactcct catcaccggt tttctttcct ctggagggtt
    16261 tggcattgcc gctataaccg ttttctcttg gatttacaag taagcacaca tttatcatct
    16321 tacttcataa ttttgtgcaa tatgtgcatg catgtgttga gccagtagct ttggatcaat
    16381 ttttttggtc gaataacaaa tgtaacaata agaaattgca aattctaggg aacatttggt
    16441 taactaaata cgaaatttga cctagctagc ttgaatgtgt ctgtgtatat catctatata
    16501 ggtaaaatgc ttggtatgat acctattgat tgtgaatagg tacgcaacgg gagagcaccc
    16561 acagggatca gacaagttgg acagtgcaag gatgaagttg ggaagcaaag ctcaggatct
    16621 gaaagacaga gctcagtact acggacagca acatactggt ggggaacatg accgtgaccg
    16681 tactcgtggt ggccagcaca ctactatgag cgagctgatt aaggagaaca tgcacatgaa
    16741 gctgtacatg gagggcaccg tgaacaacca ccacttcaag tgcacatccg agggcgaagg
    16801 caagccctac gagggcaccc agaccatgag aatcaaggtg gtcgagggcg gccctctccc
    16861 cttcgccttc gacatcctgg ctaccagctt catgtacggc agcagaacct tcatcaacca
    16921 cacccagggc atccccgact tctttaagca gtccttccct gagggcttca catgggagag
    16981 agtcaccaca tacgaagacg ggggcgtgct gaccgctacc caggacacca gcctccagga
    17041 cggctgcctc atctacaacg tcaagatcag aggggtgaac ttcccatcca acggccctgt
    17101 gatgcagaag aaaacactcg gctgggaggc caacaccgag atgctgtacc ccgctgacgg
    17161 cggcctggaa ggcagaagcg acatggccct gaagctcgtg ggcgggggcc acctgatctg
    17221 caacttcaag accacataca gatccaagaa acccgctaag aacctcaaga tgcccggcgt
    17281 ctactatgtg gaccacagac tggaaagaat caaggaggcc gacaaagaga cctacgtcga
    17341 gcagcacgag gtggctgtgg ccagatactg cgacctccct agcaaactgg ggcacaagtg
    17401 atctagtaac atagatgaca ccgcgcgcga taatttatcc tagtttgcgc gctatatttt
    17461 gttttctatc gcgtattaaa tgtataattg cgggactcta atcataaaaa cccatctcat
    17521 aaataacgtc atgcattaca tgttaattat tacatgctta acgtaattca acagaaatta
    17581 tatgataatc atcgcaagac cggcaacagg attcaatctt aagaaacttt attgccaaat
    17641 gtttgaacga taagcttggc actggccgtc gttttacaac gtcgtgactg ggaaaaccct
    17701 ggcgttaccc aacttaatcg ccttgcagca catccccctt tcgccagctg gcgtaatagc
    17761 gaagaggccc gcaccgatcg cccttcccaa cagttgcgca gcctgaatgg cgaatgagct
    17821 tgagcttgga tcagattgtc gtttcccgcc ttcagtttaa actatcagtg tttgacagga
    17881 tatattggcg ggtaaaccta agagaaaaga gcgtttatta gaataatcgg atatttaaaa
    17941 gggcgtgaaa aggtttatcc gttcgtccat ttgtatgtgc atgccaacca cagggttccc
    18001 ctcgggatca aagtacttta aagtacttta aagtacttta a
//
