LOCUS       sequence-350967-        3615 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Mammalian cell expression of SARS-CoV-2 Spike protein variant 
            OMICRON with furin side replaced by GSAS and with 2 Proline 
            substitution at 986 and 987.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 3615)
  AUTHORS   Gobeil SM, Henderson R, Stalls V, Janowska K, Huang X, May A, 
            Speakman M, Beaudoin E, Manne K, Li D, Parks R, Barr M, Deyton M, 
            Martin M, Mansouri K, Edwards RJ, Eaton A, Montefiori DC, Sempowski 
            GD, Saunders KO, Wiehe K, Williams W, Korber B, Haynes BF, Acharya P
  TITLE     Structural diversity of the SARS-CoV-2 Omicron spike.
  JOURNAL   Mol Cell. 2022 Jun 2;82(11):2050-2068.e6. doi: 
            10.1016/j.molcel.2022.03.028. Epub 2022 Mar 25.
  PUBMED    35447081
REFERENCE   2  (bases 1 to 3615)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1016/j.molcel.2022.03.028"; journalName: "Mol Cell"; date: 
            "2022-06-2- 2"; volume: "82"; issue: "11"; pages: "2050-2068.e6"
COMMENT     Sequence Label: p-alpha-H-S-GSAS-2P-OMICRON
FEATURES             Location/Qualifiers
     source          1..3615
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 ctgctcgtat ttgccgagct cctgcaggtc gatcagggac tcgttcaggt tcttggccac
       61 ctcgttcagt ctgtcgattt ccttttggat gttcaccacg ctggcgttaa tgccactgat
      121 gtcgcccagg tccacatcgg ggctggtgtg gtttttaaag tacttgtcca gctcttcctt
      181 aaaagagtcc agctcaggtt gcagagggtc gtacactgtg ttgttcacga ttccgatgac
      241 cacgtcacaa ttgccactca cgaaggtgtt gtcggtggtg ataatctggg gttcgtagaa
      301 gtttctttgt gtcacgaacc agtgtgtgcc attggaaacg aaaacgccct ctcttgggaa
      361 gtgggccttg ccgtcgtggc agatggcagg ggcggttgtg aaattcttct cttgggcagg
      421 cacgtatgtc acatgcagga acaccacgcc gtgcggcgcg ctctggggga agctcatcag
      481 gtgatagcct ttgccgcaga agtcaacgcg tttagactgt cccagcacac actcggacat
      541 cttggtagcg gcgagattgg cgctggctct tatttcagcg gccctgatca gctgttgggt
      601 cacgtaggtt tgcagggact gcagtctgcc tgtgatcagt ctatcgatct ggacttcggc
      661 ttctggaggg tccagtctag agaagatatc gttcagcaca gagctgatgg cgccaaactt
      721 gctgctgagc tgcttcacca gggtgttcag ggcttgggcg ttgtgattca ccacgtcctg
      781 cagtttgccc agggcgctgg cggtagagga gagggagtcc tggatcttgc cgatggcaga
      841 attgaactgg ttagcgatca gcttctggtt ttcatacagc acgttctggg tcacgccgat
      901 tccgttgaat ctataggcca tctgcatggc aaaggggatc tgcagggcgg cgccggcgcc
      961 aaatgtccac ccagatgtga tggtgccagc cagcagggca gaggtgtact gagcgatcat
     1021 ctcgtcggtc agcagaggtg ggagaactgt caggcccttg aatttctggg cgcagatcag
     1081 atctctggcg gctatgtcgc ccaggcaatc gccatactgt ttgataaagc cggcatcggc
     1141 cagggtgacc ttgttgaaca gcagatcctc gataaagctc cgcttgctag gcttagaagg
     1201 atcagggaga atctggctaa agttaaagcc gccgaagtac ttgataggtg gggtcttgta
     1261 gatctgcttc acttgggcga acacctcctg ggtatttttg tcctgttcca cggcgattcc
     1321 ggtcagcgcc cgcttcagtt gggtgcaaaa ggagccgtat tgcagcagca ggttgctgca
     1381 ttcagtgctg tcgccacaga tgtacattgt acagtccacg ctggtcttgg tcatgctcac
     1441 gggcaggatc tctgttgtga cgctaattgt aaagttggtg ggaatggcga tagagttgtt
     1501 ggaataggcc acgctgttct ctgcgcccag gctcatggtg taggcgatga tgctctggct
     1561 agctacagag gaagcagacc catggctctt tgtctgggtc tggtagctgg cacagatgcc
     1621 ggcgccgata gggatgtcgc actcgtaact gttattcacg tactcggcgc cgatcagaca
     1681 tccggccctg gtctggaaca cattggagcc agtggagtac actctccaag taggtgtcag
     1741 ctgatcggcg tggatggcca caggaacctc ggtgcagtta acaccttggt acagcacagc
     1801 cacctggttg ctggtattgg tcccgggggt gatcacagaa actcctccga aggagcaggg
     1861 tgtaatatcc aggatttcca gggtctgtgg atctctgacg gcatctgtgg tgtcagcgat
     1921 atcacggccg aactgctgga aggggaggaa ctttttgttg ctttcggtca gcacgccggt
     1981 ccccttcagg ccgttgaagt tgaagttcac gcatttgttc ttaaccagat tggtggactt
     2041 cttaggaccg cagacggtgg cgggggcgtg gagtaactcg aaggacagca cgaccacccg
     2101 gtatggctgg tggccgactc cataggtagg ccggaagctg tagcttcgca gagggaagta
     2161 acagttgaag ccggccaccc cgttacaagg cttgttaccg gcctggtaga tctctgtgga
     2221 gatgtctctc tcgaaaggtt tcaggttaga cttgcgaaac agccggtaca ggtagttgta
     2281 gttgccgctc accttgctat ccagcttgtt agagttccag gcgatcacgc agcctgtaaa
     2341 atcatcaggc agcttatagt tgtagtcagc gatgttaccg gtctggcctg gtgcgatctg
     2401 ccgcacctca tcgcctctaa ttacgaagga gtcggcgtac acgttggtga agcacaggtc
     2461 attcagcttt gttggggaaa cgccgtagca cttgaaggtg aagaaagggg cgaggttata
     2521 cagcacggag tagtcggcca cacaattgct gattctcttt ctattccagg cgtaaacgga
     2581 ggcaaatctt gtggcgttaa acacctcgtc gaaggggcag aggttggtaa tgtttggaaa
     2641 tcgcacgatg ctctctgtag gctgcacccg gaagttgctg gtctggtaga tgcccttttc
     2701 cacggtgaag gacttcaggg tgcactttgt ctcagagaga gggtccaggg cgcagtcgac
     2761 ggcgtctgtg attgtgccgt tctcgttgta cttcagcagg aaggttctag gttgcaggta
     2821 gcccacatag taggctgcag ctccggcggt ccatccgctg ctgctgtcgc caggagtcag
     2881 gtaggatcta tgcagggcca gcagggtttg gaaccgcgtt atgttgatgc ctatgggcag
     2941 gtcgaccagg ggttccaggg cgctgaagcc ctgagggagg tcttcaggct cccggacgat
     3001 gatgggtgtg tgcttggagt agattttgaa gtagccgtcg atgttcttga acacgaattc
     3061 tctcaggttc ttgaagttgc cttgtttccc ctcaaggtcc atcagaaaag gctgagagac
     3121 gtactcgaat gtgcagttgt tggcgctgct gtagactctg aactcgcttt ccatccagct
     3181 cttgttgttc ttgtggtcca ggaaaggatc attgcaaaac tggaactcgc acaccttgat
     3241 cacgacgttc gtggcattgt tcacgatcag gaggctctgt gttttgctat ccagggtggt
     3301 gccgaagatc cagccccgga tgatgttact cttctcgata ctggcgaagt aaactccatc
     3361 attgaatggc aggacggggt tatcaaaccg cttggttccg tttgtgccgc tgatgacgtg
     3421 gaaccatgtc acgttgctga agaacggcag gaagaggtcc tgagtgctgt gcaggacgct
     3481 agatctgaac accttgtcag ggtagtacac gccccgtgta aagctgttgg tgtaggctgg
     3541 tgggagctgg gttcgggtgg tcaggttcac gcactggctg ctcaccagag gcaggagcac
     3601 caggaacacg aacat
//
