LOCUS       sequence-356432-        2397 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Expresses SHIP2-Enzyme domain flanked by RBP.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2397)
  AUTHORS   Sudan R, Fernandes S, Srivastava N, Pedicone C, Meyer ST, Chisholm 
            JD, Engelman RW, Kerr WG
  TITLE     LRBA Deficiency Can Lead to Lethal Colitis That Is Diminished by 
            SHIP1 Agonism.
  JOURNAL   Front Immunol. 2022 May 4;13:830961. doi: 10.3389/fimmu.2022.830961.
            eCollection 2022.
  PUBMED    35603158
REFERENCE   2  (bases 1 to 2397)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Front 
            Immunol."; date: "2022-05-4"; volume: "13:830961. doi"; pages: " 
            10.3389/fimmu.2022.830961. eCollection 2022"
COMMENT     Sequence Label: pS97splitRBP_S2-Enz
FEATURES             Location/Qualifiers
     source          1..2397
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             13..30
                     /codon_start=1
                     /product="6xHis affinity tag"
                     /label=6xHis
                     /translation="HHHHHH"
     CDS             631..654
                     /codon_start=1
                     /product="recognition and cleavage site for human 
                     rhinovirus 3C and PreScission proteases"
                     /label=HRV 3C site
                     /translation="LEVLFQGP"
     CDS             complement(1361..1372)
                     /codon_start=1
                     /product="Factor Xa recognition and cleavage site"
                     /label=Factor Xa site
                     /translation="IEGR"
     CDS             2053..2076
                     /codon_start=1
                     /product="recognition and cleavage site for human 
                     rhinovirus 3C and PreScission proteases"
                     /label=HRV 3C site
                     /translation="LEVLFQGP"
ORIGIN
        1 atgggtagct cacaccatca ccatcaccat tcgagctcgg gcgacgtagt gtcgcatatc
       61 gcaagcgata acgtcaaggg aggtgagatg gctgccgagt tcattgcgaa agccttaaag
      121 ggcaaaggga acgtcgtgga attagagggc atcccaggag cgtcggcagc tcgtgaccgc
      181 ggaaaagggt ttgacgaggc tattgctaag tacccagaca tcaagatcgt ggccaaacaa
      241 gccgccgact ttgatcgcag taagggtttg agcgttatgg aaaacatctt acaggcgcaa
      301 ccgaaaattg atgcagtgtt cgcgcaaaat gatgagatgg ctttgggtgc aattaaagca
      361 attgaggctg cgaaccgcca aggtattatc gtggtcggct tcgacggtac agaggacgcg
      421 ttgaaggcga ttaaagaagg gaagatggcg gcgaccattg cacaacagcc ggccttgatg
      481 ggctcgcttg gggtcgagat ggctgataaa tatcttaagg gcgaaaaaat ccctaatttt
      541 atccccgctg aattgaaatt gatcactaaa gaaaatgtgc aagggggttc tgcctctgga
      601 gggacaagtg gtggatcgag tgcggccggt ttggaggttt tattccaggg tccagcggcc
      661 gccaagcact ccaagcagga cgagcccgac atgatctcag tcttcatagg cacctggaac
      721 atgggaagtg taccacctcc aaaaaacgtg acatcctggt tcacatcgaa gggtctgggg
      781 aagaccctgg acgaggtcac agtgaccata ccccatgaca tctatgtctt tgggacccag
      841 gagaactcag tgggcgaccg cgagtggctg gacctactgc gcgggggcct caaggagctt
      901 acggatctgg attaccgccc gattgccatg caatcactgt ggaatatcaa ggtggcagtg
      961 ctggtcaagc cagagcacga gaaccgtatc agccatgtca gtacgtccag tgtgaagact
     1021 ggcatcgcca acaccctggg gaacaagggg gctgtgggcg tctccttcat gtttaatggc
     1081 acctcatttg gctttgtgaa ttgtcacctc acctcgggaa atgagaagac ggctcggagg
     1141 aaccaaaact acttggacat cctgcggctg ctctcgctgg gcgaccggca gctcaatgcc
     1201 tttgacatct ctctgcgttt cacacacctc ttctggtttg gggacctcaa ctaccgcctg
     1261 gacatggata tccaggagat cctgaactac atcagcagga aagagtttga gcccctcctc
     1321 agggtggacc agctcaacct ggagcgggag aagcacaagg tcttccttcg attcagtgag
     1381 gaggagatct ccttcccacc cacctaccgc tatgagcggg gttcccggga cacatatgcc
     1441 tggcacaagc agaagccaac tggggtccgg accaatgtgc cctcatggtg tgaccggatt
     1501 ctgtggaaat cctaccctga aactcacatc atctgcaatt cttatggttg cactgatgac
     1561 atcgtcacca gcgaccattc ccccgtgttt gggacatttg aggttggagt tacctcccag
     1621 ttcatctcca agaaagggct ctcaaagact tcagaccagg cctacattga gtttgagagc
     1681 atcgaggcca ttgtgaagac agccagccgc accaagttct tcatcgagtt ctactctacc
     1741 tgcctggagg aatacaagaa gagctttgag aatgatgccc agagcagtga caacatcaac
     1801 ttcctcaaag tgcagtggtc ttcacgccag ctgcccacgc tcaaaccaat tctggctgat
     1861 atcgagtacc tgcaggacca gcacctcctg ctcacagtca agtccatgga tggctatgaa
     1921 tcctatgggg agtgtgtggt tgcactcaaa tccatgatcg gcagcacggc ccaacagttc
     1981 ctgaccttcc tatcccaccg tggcgaggag acaggcaata tcagaggctc catgaaggtg
     2041 ggatccggtg gcttagaagt attattccaa ggtccaggtt cgtcaggagg gacggcatct
     2101 ggagggaaag aaggcaaaac catcggtctg gtcatcagta ccttgaataa ccccttcttt
     2161 gtaaccttga aaaatggcgc tgaggagaaa gcgaaggaac tgggatacaa gatcatcgta
     2221 gaggattccc agaatgactc ctcgaaggag ttatccaacg ttgaggattt aattcaacag
     2281 aaggtcgacg tactgctgat taaccctgta gattcggatg ctgttgtaac cgccattaag
     2341 gaagcaaata gcaagaacat tccagttatt actattgatc gctcggccaa cgggtaa
//
