LOCUS       sequence-36766-e         840 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 840)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 840)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PIK3CA
FEATURES             Location/Qualifiers
     source          1..840
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    22..121
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 gggggggatt cagcctggat ggcaataatg attttatttt gactgatagt gacctgttcg
       61 ttgcaacaaa ttgataagca atgctttctt ataatgccaa ctttgtacaa gaaagttggc
      121 aagttcaatg catgctgttt aattgtgtgg aagatccaat ccatttttgt tgtccagcca
      181 ccatgatgtg catcattcat ttgtttcatg aaatactcca aaacctcttg ctcagtttta
      241 tctaaggcta gggtctttcg aatgtatgca atgtcatcaa aagattgtag ttctggcatt
      301 ccagagccaa gcatcattga gaaaagattt atgaagagat tggcatgctg tcgaatagct
      361 agataagcct tgtaacacat ctcctgaaac ctctcaaatt ctcttgtctt tgtgcattct
      421 tgggctcctt tactaatcac tattaagaaa tcctgtgtca aaacaaatgg cacacgttct
      481 cgtttataac caaatttttt cttcttgtga tccaaaaagt gtccaaaatc tatatgaaac
      541 agttgtccat cgtctttcac catgatgtta ctattgtgac gatctccaat tcccaaaatg
      601 aaggtagcta cacagtatcc agcacatgaa cgtgtaaaca ggtcaatggc tgcatcatat
      661 atttctcctt tgttcttgtc tttgagccac tgatgtagtg tgtggctgtt gaactgcagt
      721 gcacctttca agccgccttt gcactgaatt tgcataatag tgtgagaatt tcgcacccac
      781 ctcataagtc ccacacagtc accgattgac agacaaccat aaggtaacat tcgaagatca
//
