LOCUS       sequence-373067-        1089 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Expression of N-terminally mGFP labelled mutated FGFR3 (isoform 
            IIIc)-K508M leads to inactive receptor (target mutation: c.1523A>T; 
            silent mutation added on purpose: c.1515A>T).
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1089)
  AUTHORS   Hartl I, Brumovska V, Striedner Y, Yasari A, Schutz GJ, Sevcsik E, 
            Tiemann-Boege I
  TITLE     Measurement of FGFR3 signaling at the cell membrane via total 
            internal reflection fluorescence microscopy to compare the 
            activation of FGFR3 mutants.
  JOURNAL   J Biol Chem. 2023 Feb;299(2):102832. doi: 10.1016/j.jbc.2022.102832.
            Epub 2022 Dec 27.
  PUBMED    36581204
REFERENCE   2  (bases 1 to 1089)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "J Biol 
            Chem."; date: "2023-02"; volume: "299(2):102832. doi"; pages: " 
            10.1016/j.jbc.2022.102832. Epub 2022 Dec 27"
COMMENT     Sequence Label: pcDNA3.1_mGFP-FGFR3-K508M
FEATURES             Location/Qualifiers
     source          1..1089
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 ggctgtcctc aggggagggc cccacgctgg ccaatgtctc cgagctcgag ctgcctgccg
       61 accccaaatg ggagctgtct cgggcccggc tgaccctggg caagcccctt ggggagggct
      121 gcttcggcca ggtggtcatg gcggaggcca tcggcattga caaggaccgg gccgccaagc
      181 ctgtcaccgt tgccgtgatg atgctgaaag acgatgccac tgacaaggac ctgtcggacc
      241 tggtgtctga gatggagatg atgaagatga tcgggaaaca caaaaacatc atcaacctgc
      301 tgggcgcctg cacgcagggc gggcccctgt acgtgctggt ggagtacgcg gccaagggta
      361 acctgcggga gtttctgcgg gcgcggcggc ccccgggcct ggactactcc ttcgacacct
      421 gcaagccgcc cgaggagcag ctcaccttca aggacctggt gtcctgtgcc taccaggtgg
      481 cccggggcat ggagtacttg gcctcccaga agtgcatcca cagggacctg gctgcccgca
      541 atgtgctggt gaccgaggac aacgtgatga agatcgcaga cttcgggctg gcccgggacg
      601 tgcacaacct cgactactac aagaagacaa ccaacggccg gctgcccgtg aagtggatgg
      661 cgcctgaggc cttgtttgac cgagtctaca ctcaccagag tgacgtctgg tcctttgggg
      721 tcctgctctg ggagatcttc acgctggggg gctccccgta ccccggcatc cctgtggagg
      781 agctcttcaa gctgctgaag gagggccacc gcatggacaa gcccgccaac tgcacacacg
      841 acctgtacat gatcatgcgg gagtgctggc atgccgcgcc ctcccagagg cccaccttca
      901 agcagctggt ggaggacctg gaccgtgtcc ttaccgtgac gtccaccgac gagtacctgg
      961 acctgtcggc gcctttcgag cagtactccc cgggtggcca ggacaccccc agctccagct
     1021 cctcagggga cgactccgtg tttgcccacg acctgctgcc cccggcccca cccagcagtg
     1081 ggggctcgc
//
