LOCUS       sequence-377405-        3756 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  expressing SARS-CoV-2 XBB spike protein for pseudovirus production.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 3756)
  AUTHORS   Zhou P, Song G, Liu H, Yuan M, He WT, Beutler N, Zhu X, Tse LV, 
            Martinez DR, Schafer A, Anzanello F, Yong P, Peng L, Dueker K, 
            Musharrafieh R, Callaghan S, Capozzola T, Limbo O, Parren M, Garcia 
            E, Rawlings SA, Smith DM, Nemazee D, Jardine JG, Safonova Y, Briney 
            B, Rogers TF, Wilson IA, Baric RS, Gralinski LE, Burton DR, Andrabi 
            R
  TITLE     Broadly neutralizing anti-S2 antibodies protect against all three 
            human betacoronaviruses that cause deadly disease.
  JOURNAL   Immunity. 2023 Mar 14;56(3):669-686.e7. doi: 
            10.1016/j.immuni.2023.02.005. Epub 2023 Feb 16.
  PUBMED    36889306
REFERENCE   2  (bases 1 to 3756)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1016/j.immuni.2023.02.005"; journalName: "Immunity"; date: 
            "2023-03-14- 14"; volume: "56"; issue: "3"; pages: "669-686.e7"
COMMENT     Sequence Label: pcDNA3.3_SARS2_XBB
FEATURES             Location/Qualifiers
     source          1..3756
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgtttgtgt tcctggtgct gctgccactg gtgtccagcc agtgtgtgaa cctgatcacc
       61 aggacccaat cctacaccaa ctccttcacc aggggagtct actaccctga caaggtgttc
      121 aggtcctctg tgctgcacag cacccaggac ctgttcctgc cattcttcag caatgtgacc
      181 tggttccatg ccatccatgt gtctggcacc aatggcacca agaggtttga caaccctgcg
      241 ctgccattca atgatggagt ctactttgcc agcacagaga agagcaacat catcaggggc
      301 tggatttttg gcaccaccct ggacagcaag acccagtccc tgctgattgt gaacaatgcc
      361 accaatgtgg tgattaaggt gtgtgagttc cagttctgta atgacccatt cctggacgtc
      421 taccagaaga acaacaagtc ctggatggag tctgagttca gggtctactc ctctgccaac
      481 aactgtacct ttgaatatgt gagccaacca ttcctgatgg acttggaggg caaggagggc
      541 aacttcaaga acctgaggga gtttgtgttc aagaacattg atggctactt caagatttac
      601 agcaaacaca caccaatcaa cctggagagg gacctgccac agggcttctc tgccttggaa
      661 ccactggtgg acctgccaat tggcatcaac atcaccaggt tccagaccct gctggctctg
      721 cacaggtcct acctgacacc tggagactcc tcctctggct ggacagcagg agcagcagcc
      781 tactatgtgg gctacctcca accaaggacc ttcctgctga aatacaatga gaatggcacc
      841 atcacagatg ctgtggactg tgccctggac ccactgtctg agaccaagtg taccctgaaa
      901 tccttcacag tggagaaggg catctaccag accagcaact tcagggtcca accaacagag
      961 agcattgtga ggtttccaaa catcaccaac ctgtgtccat ttcacgaggt gttcaatgcc
     1021 accacgtttg cctctgtcta tgcctggaac aggaagagga ttagcaactg tgtggctgac
     1081 tactctgtga tctacaactt tgcccccttc ttcgccttca agtgttatgg agtgagccca
     1141 accaaactga atgacctgtg tttcaccaat gtctatgctg actcctttgt gattagggga
     1201 aatgaggtga gtcagattgc ccctggacaa acaggcaaca ttgctgacta caactacaaa
     1261 ctgcctgatg acttcacagg ctgtgtgatt gcctggaaca gcaacaagct ggacagcaag
     1321 ccgtcaggca actacaacta cctctacaga ctgttcagga agagcaagct gaaaccattt
     1381 gagagggaca tcagcacaga gatttaccag gctggcaaca aaccatgtaa tggagtggcg
     1441 ggctcgaact gttactctcc actccagtcc tatggcttca gaccaaccta tggagtgggc
     1501 caccaaccat acagggtggt ggtgctgtcc tttgaactgc tccatgcccc tgccacagtg
     1561 tgtggaccaa agaagagcac caacctggtg aagaacaagt gtgtgaactt caacttcaat
     1621 ggactgacag gcacaggagt gctgacagag agcaacaaga agttcctgcc attccaacag
     1681 tttggcaggg acattgctga caccacagat gctgtgaggg acccacagac cttggagatt
     1741 ctggacatca caccatgttc ctttggagga gtgtctgtga ttacacctgg caccaacacc
     1801 agcaaccagg tggctgtgct ctaccagggt gtgaactgta ctgaggtgcc tgtggctatc
     1861 catgctgacc aacttacacc aacctggagg gtctacagca caggcagcaa tgtgttccag
     1921 accagggctg gctgtctgat tggagcagag tatgtgaaca actcctatga gtgtgacatc
     1981 ccaattggag caggcatctg tgcctcctac cagacccaga ccaagagcca taggagggca
     2041 aggtctgtgg caagccagag catcattgcc tacacaatga gtctgggagc agagaactct
     2101 gtggcttaca gcaacaacag cattgccatc ccaaccaact tcaccatctc tgtgaccaca
     2161 gaaattctgc ctgtgagtat gaccaagacc tctgtggact gtacaatgta tatctgtgga
     2221 gacagcacag agtgtagcaa cctgctgctc caatatggct ccttctgtac ccaacttaag
     2281 agggctctga caggcattgc tgtggaacag gacaagaaca cccaggaggt gtttgcccag
     2341 gtgaagcaga tttacaagac acctccaatc aagtactttg gaggcttcaa cttcagccag
     2401 attctgcctg acccaagcaa gccaagcaag aggtccttca ttgaggacct gctgttcaac
     2461 aaggtgaccc tggctgatgc tggcttcatc aagcaatatg gagactgtct gggagacatt
     2521 gctgcaaggg acctgatttg tgcccagaag ttcaatggac tgaccgtgct gcctccactg
     2581 ctgacagatg agatgattgc ccaatacacc tctgccctgc tggctggcac catcacctct
     2641 ggctggacct ttggagcagg agcagccctc caaatcccat ttgctatgca gatggcttac
     2701 aggttcaatg gcattggagt gacccagaat gtgctctatg agaaccagaa actgattgcc
     2761 aaccagttca actctgccat tggcaagatt caggactccc tgtccagcac agcctctgcc
     2821 ctgggcaaac tccaagatgt ggtgaaccat aatgcccagg ctctgaacac cctggtgaag
     2881 caactttcca gcaagtttgg agccatctcc tctgtgctga atgacatcct gagcagactg
     2941 gacaaggtgg aggctgaggt ccagattgac agactgatta caggcagact ccaatccctc
     3001 caaacctatg tgacccaaca acttatcagg gctgctgaga ttagggcatc tgccaacctg
     3061 gctgccacca agatgagtga gtgtgtgctg ggacaaagca agagggtgga cttctgtggc
     3121 aagggctacc acctgatgag ttttccacag tctgcccctc atggagtggt gttcctgcat
     3181 gtgacctatg tgcctgccca ggagaagaac ttcaccacag cccctgccat ctgccatgat
     3241 ggcaaggctc actttccaag ggagggagtg tttgtgagca atggcaccca ctggtttgtg
     3301 acccagagga acttctatga accacagatt atcaccacag acaacacctt tgtgtctggc
     3361 aactgtgatg tggtgattgg cattgtgaac aacacagtct atgacccact ccaacctgaa
     3421 ctggactcct tcaaggagga actggacaaa tacttcaaga accacaccag ccctgatgtg
     3481 gacctgggag acatctctgg catcaatgcc tctgtggtga acatccagaa ggagattgac
     3541 agactgaatg aggtggctaa gaacctgaat gagtccctga ttgacctcca agaactgggc
     3601 aaatatgaac aatacatcaa gtggccatgg tacatctggc tgggcttcat tgctggactg
     3661 attgccattg tgatggtgac cataatgctg tgttgtatga cctcctgttg ttcctgtctg
     3721 aaaggctgtt gttcctgtgg ctcctgttgt aagtga
//
