LOCUS       sequence-379399-       40148 bp    DNA     circular UNA 15-DEC-2025
DEFINITION  Adenoviral expression vector encoding sgRNAs targeting Trp53 and 
            Rb1, Cre and Cas9.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 40148)
  AUTHORS   Merle N, Elmshauser S, Strassheimer F, Wanzel M, Konig AM, Funk J, 
            Neumann M, Kochhan K, Helmprobst F, Pagenstecher A, Nist A, 
            Mernberger M, Schneider A, Braun T, Borggrefe T, Savai R, Timofeev 
            O, Stiewe T
  TITLE     Monitoring autochthonous lung tumors induced by somatic CRISPR gene 
            editing in mice using a secreted luciferase.
  JOURNAL   Mol Cancer. 2022 Oct 3;21(1):191. doi: 10.1186/s12943-022-01661-2.
  PUBMED    36192757
REFERENCE   2  (bases 1 to 40148)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Mol 
            Cancer."; date: "2022-10-3"; volume: "21(1):191. doi"; pages: " 
            10.1186/s12943-022-01661-2"
COMMENT     Sequence Label: pAd-PR.CC9
FEATURES             Location/Qualifiers
     source          1..40148
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     promoter        29..277
                     /label=U6 promoter
                     /note="RNA polymerase III promoter for human U6 snRNA 
                     (Domitrovich & Kunkel, 2003)"
     misc_RNA        299..374
                     /label=gRNA scaffold
                     /note="guide RNA scaffold for the Streptococcus pyogenes 
                     CRISPR/Cas9 system"
     promoter        381..629
                     /label=U6 promoter
                     /note="RNA polymerase III promoter for human U6 snRNA 
                     (Domitrovich & Kunkel, 2003)"
     misc_RNA        650..725
                     /label=gRNA scaffold
                     /note="guide RNA scaffold for the Streptococcus pyogenes 
                     CRISPR/Cas9 system"
     enhancer        735..1038
                     /label=CMV enhancer
                     /note="human cytomegalovirus immediate early enhancer"
     promoter        1039..1242
                     /label=CMV promoter
                     /note="human cytomegalovirus (CMV) immediate early 
                     promoter"
     primer_bind     1193..1213
                     /label=CMV-F
                     /note="Human CMV immediate early promoter, forward primer"
     primer_bind     1239..1263
                     /label=LNCX
                     /note="Human CMV promoter, forward primer"
     CDS             1331..1351
                     /codon_start=1
                     /product="nuclear localization signal of SV40 (simian virus
                     40) large T antigen"
                     /label=SV40 NLS
                     /translation="PKKKRKV"
     CDS             1352..2377
                     /codon_start=1
                     /product="site-specific recombinase"
                     /label=Cre
                     /note="Cre is a site-specific recombinase from 
                     bacteriophage P1. Recombination occurs at loxP sequences."
                     /translation="SNLLTVHQNLPALPVDATSDEVRKNLMDMFRDRQAFSEHTWKMLQ
                     SVCRSWAAWCKLNNRKWFPAEPEDVRDYLLYLQARGLAVKTIQQHLGQLNMLHRRSGLP
                     RPSDSNAVSLVMRRIRKENVDAGERAKQALAFERTDFDQVRSLMENSDRCQDIRNLAFL
                     GIAYNTLLRIAEIARIRVKDISRTDGGRMLIHIGRTKTLVSTAGVEKALSLGVTKLVER
                     WISVSGVADDPNNYLFCRVRKNGVAAPSATSQLSTRALEGIFEATHRLIYGAKDDSGQR
                     YLAWSGHSARVGAARDMARAGVSIPEIMQAGGWTNVNIVMNYIRNLDSETGAMVRLLED
                     GD"
     CDS             2387..2440
                     /codon_start=1
                     /product="2A peptide from Thosea asigna virus capsid 
                     protein"
                     /label=T2A
                     /note="Eukaryotic ribosomes fail to insert a peptide bond 
                     between the Gly and Pro residues, yielding separate 
                     polypeptides."
                     /translation="EGRGSLLTCGDVEENPGP"
     CDS             2444..2509
                     /codon_start=1
                     /product="three tandem FLAG(R) epitope tags, followed by an
                     enterokinase cleavage site"
                     /label=3xFLAG
                     /translation="DYKDHDGDYKDHDIDYKDDDDK"
     CDS             2516..2536
                     /codon_start=1
                     /product="nuclear localization signal of SV40 (simian virus
                     40) large T antigen"
                     /label=SV40 NLS
                     /translation="PKKKRKV"
     CDS             2561..6661
                     /codon_start=1
                     /product="Cas9 (Csn1) endonuclease from the Streptococcus 
                     pyogenes Type II CRISPR/Cas system"
                     /label=Cas9
                     /note="generates RNA-guided double strand breaks in DNA"
                     /translation="DKKYSIGLDIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKN
                     LIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESF
                     LVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKF
                     RGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLE
                     NLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQI
                     GDQYADLFLAAKNLSDAILLSDILRVNTEITKAPLSASMIKRYDEHHQDLTLLKALVRQ
                     QLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLR
                     KQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGN
                     SRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYF
                     TVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDS
                     VEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERL
                     KTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQ
                     LIHDDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRH
                     KPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYL
                     YYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVPS
                     EEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKHV
                     AQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLN
                     AVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIGKATAKYFFYSNIMNFFKTE
                     ITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKE
                     SILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGIT
                     IMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNEL
                     ALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADA
                     NLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLD
                     ATLIHQSITGLYETRIDLSQLGGD"
     CDS             2561..6661
                     /codon_start=1
                     /product="Cas9 (Csn1) endonuclease from the Streptococcus 
                     pyogenes Type II CRISPR/Cas system"
                     /label=Cas9
                     /note="generates RNA-guided double strand breaks in DNA"
                     /translation="DKKYSIGLDIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKN
                     LIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESF
                     LVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKF
                     RGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLE
                     NLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQI
                     GDQYADLFLAAKNLSDAILLSDILRVNTEITKAPLSASMIKRYDEHHQDLTLLKALVRQ
                     QLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLR
                     KQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGN
                     SRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYF
                     TVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDS
                     VEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERL
                     KTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQ
                     LIHDDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRH
                     KPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYL
                     YYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVPS
                     EEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKHV
                     AQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLN
                     AVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIGKATAKYFFYSNIMNFFKTE
                     ITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKE
                     SILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGIT
                     IMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNEL
                     ALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADA
                     NLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLD
                     ATLIHQSITGLYETRIDLSQLGGD"
     CDS             6662..6709
                     /codon_start=1
                     /product="bipartite nuclear localization signal from 
                     nucleoplasmin"
                     /label=nucleoplasmin NLS
                     /translation="KRPAATKKAGQAKKKK"
     primer_bind     complement(6737..6754)
                     /label=BGH-rev
                     /note="Bovine growth hormone terminator, reverse primer. 
                     Also called BGH reverse"
     polyA_signal    6743..6950
                     /label=bGH poly(A) signal
                     /note="bovine growth hormone polyadenylation signal"
     protein_bind    complement(6959..6983)
                     /gene="mutant version of attB"
                     /label=attB2
                     /bound_moiety="BP Clonase(TM)"
                     /note="recombination site for the Gateway(R) BP reaction"
     misc_feature    join(10533..10598,10599..10636)
                     /label=Ad SA
                     /note="adenovirus major late transcript splice acceptor 
                     (Friedrich and Soriano, 1991)"
     CDS             complement(17732..17743)
                     /codon_start=1
                     /product="Factor Xa recognition and cleavage site"
                     /label=Factor Xa site
                     /translation="IEGR"
     regulatory      25215..25224
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
     repeat_region   37440..37542
                     /label=ITR
                     /note="inverted terminal repeat of human adenovirus 
                     serotype 5"
     rep_origin      complement(37766..38354)
                     /direction=LEFT
                     /label=ori
                     /note="high-copy-number ColE1/pMB1/pBR322/pUC origin of 
                     replication"
     primer_bind     complement(37846..37865)
                     /label=pBR322ori-F
                     /note="pBR322 origin, forward primer"
     CDS             complement(join(38506..39297,39298..39366))
                     /codon_start=1
                     /gene="bla"
                     /product="beta-lactamase"
                     /label=AmpR
                     /note="confers resistance to ampicillin, carbenicillin, and
                     related antibiotics"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
     primer_bind     39129..39148
                     /label=Amp-R
                     /note="Ampicillin resistance gene, reverse primer"
     promoter        complement(39367..39471)
                     /gene="bla"
                     /label=AmpR promoter
     primer_bind     39539..39557
                     /label=pBRforEco
                     /note="pBR322 vectors, upsteam of EcoRI site, forward 
                     primer"
     repeat_region   39630..39732
                     /label=ITR
                     /note="inverted terminal repeat of human adenovirus 
                     serotype 5"
     misc_signal     39820..39970
                     /label=Ad5 Psi
                     /note="packaging signal for adenovirus serotype 5"
     protein_bind    join(40141..40148,1..17)
                     /gene="mutant version of attB"
                     /label=attB1
                     /bound_moiety="BP Clonase(TM)"
                     /note="recombination site for the Gateway(R) BP reaction"
ORIGIN
        1 gtacaaaaaa gcaggcacca tggaggctga gggcctattt cccatgattc cttcatattt
       61 gcatatacga tacaaggctg ttagagagat aattggaatt aatttgactg taaacacaaa
      121 gatattagta caaaatacgt gacgtagaaa gtaataattt cttgggtagt ttgcagtttt
      181 aaaattatgt tttaaaatgg actatcatat gcttaccgta acttgaaagt atttcgattt
      241 cttggcttta tatatcttgt ggaaaggacg aaacaccgca taaggtacca ccacgctggt
      301 tttagagcta gaaatagcaa gttaaaataa ggctagtccg ttatcaactt gaaaaagtgg
      361 caccgagtcg gtgctttttt gagggcctat ttcccatgat tccttcatat ttgcatatac
      421 gatacaaggc tgttagagag ataattggaa ttaatttgac tgtaaacaca aagatattag
      481 tacaaaatac gtgacgtaga aagtaataat ttcttgggta gtttgcagtt ttaaaattat
      541 gttttaaaat ggactatcat atgcttaccg taacttgaaa gtatttcgat ttcttggctt
      601 tatatatctt gtggaaagga cgaaacaccg aacagatttg tccttcccgg ttttagagct
      661 agaaatagca agttaaaata aggctagtcc gttatcaact tgaaaaagtg gcaccgagtc
      721 ggtgcttttt tccgcgttac ataacttacg gtaaatggcc cgcctggctg accgcccaac
      781 gacccccgcc cattgacgtc aataatgacg tatgttccca tagtaacgcc aatagggact
      841 ttccattgac gtcaatgggt ggagtattta cggtaaactg cccacttggc agtacatcaa
      901 gtgtatcata tgccaagtac gccccctatt gacgtcaatg acggtaaatg gcccgcctgg
      961 cattatgccc agtacatgac cttatgggac tttcctactt ggcagtacat ctacgtatta
     1021 gtcatcgcta ttaccatggt gatgcggttt tggcagtaca tcaatgggcg tggatagcgg
     1081 tttgactcac ggggatttcc aagtctccac cccattgacg tcaatgggag tttgttttgg
     1141 caccaaaatc aacgggactt tccaaaatgt cgtaacaact ccgccccatt gacgcaaatg
     1201 ggcggtaggc gtgtacggtg ggaggtctat ataagcagag ctcgtttagt gaaccgtcag
     1261 atcgcctgga gacgccatcc acgctgtttt gacctccata gaagacaccg actctagagg
     1321 atctaccatg cccaagaaga agaggaaggt gtccaattta ctgaccgtac accaaaattt
     1381 gcctgcatta ccggtcgatg caacgagtga tgaggttcgc aagaacctga tggacatgtt
     1441 cagggatcgc caggcgtttt ctgagcatac ctggaaaatg cttcagtccg tttgccggtc
     1501 gtgggcggca tggtgcaagt tgaataaccg gaaatggttt cccgcagaac ctgaagatgt
     1561 tcgcgattat cttctatatc ttcaggcgcg cggtctggca gtaaaaacta tccagcaaca
     1621 tttgggccag ctaaacatgc ttcatcgtcg gtccgggctg ccacgaccaa gtgacagcaa
     1681 tgctgtttca ctggttatgc ggcggatccg aaaagaaaac gttgatgccg gtgaacgtgc
     1741 aaaacaggct ctagcgttcg aacgcactga tttcgaccag gttcgttcac tcatggaaaa
     1801 tagcgatcgc tgccaggata tacgtaatct ggcatttctg gggattgctt ataacaccct
     1861 gttacgtata gccgaaattg ccaggatcag ggttaaagat atctcacgta ctgacggtgg
     1921 gagaatgtta atccatattg gcagaacgaa aacgctggtt agcaccgcag gtgtagagaa
     1981 ggcacttagc ctgggggtaa ctaaactggt cgagcgatgg atttccgtct ctggtgtagc
     2041 tgatgatccg aataactacc tgttttgccg ggtcagaaaa aatggtgttg ccgcgccatc
     2101 tgccaccagc cagctatcaa ctcgcgccct ggaagggatt tttgaagcaa ctcatcgatt
     2161 gatttacggc gctaaggatg actctggtca gagatacctg gcctggtctg gacacagtgc
     2221 ccgtgtcgga gccgcgcgag atatggcccg cgctggagtt tcaataccgg agatcatgca
     2281 agctggtggc tggaccaatg taaatattgt catgaactat atccgtaacc tggatagtga
     2341 aacaggggca atggtgcgcc tgctggaaga tggcgatgga agcggagagg gcagaggaag
     2401 tctgctaaca tgcggtgacg tcgaggagaa tcctggacct atggactata aggaccacga
     2461 cggagactac aaggatcatg atattgatta caaagacgat gacgataaga tggccccaaa
     2521 gaagaagcgg aaggtcggta tccacggagt cccagcagcc gacaagaagt acagcatcgg
     2581 cctggacatc ggcaccaact ctgtgggctg ggccgtgatc accgacgagt acaaggtgcc
     2641 cagcaagaaa ttcaaggtgc tgggcaacac cgaccggcac agcatcaaga agaacctgat
     2701 cggagccctg ctgttcgaca gcggcgaaac agccgaggcc acccggctga agagaaccgc
     2761 cagaagaaga tacaccagac ggaagaaccg gatctgctat ctgcaagaga tcttcagcaa
     2821 cgagatggcc aaggtggacg acagcttctt ccacagactg gaagagtcct tcctggtgga
     2881 agaggataag aagcacgagc ggcaccccat cttcggcaac atcgtggacg aggtggccta
     2941 ccacgagaag taccccacca tctaccacct gagaaagaaa ctggtggaca gcaccgacaa
     3001 ggccgacctg cggctgatct atctggccct ggcccacatg atcaagttcc ggggccactt
     3061 cctgatcgag ggcgacctga accccgacaa cagcgacgtg gacaagctgt tcatccagct
     3121 ggtgcagacc tacaaccagc tgttcgagga aaaccccatc aacgccagcg gcgtggacgc
     3181 caaggccatc ctgtctgcca gactgagcaa gagcagacgg ctggaaaatc tgatcgccca
     3241 gctgcccggc gagaagaaga atggcctgtt cggaaacctg attgccctga gcctgggcct
     3301 gacccccaac ttcaagagca acttcgacct ggccgaggat gccaaactgc agctgagcaa
     3361 ggacacctac gacgacgacc tggacaacct gctggcccag atcggcgacc agtacgccga
     3421 cctgtttctg gccgccaaga acctgtccga cgccatcctg ctgagcgaca tcctgagagt
     3481 gaacaccgag atcaccaagg cccccctgag cgcctctatg atcaagagat acgacgagca
     3541 ccaccaggac ctgaccctgc tgaaagctct cgtgcggcag cagctgcctg agaagtacaa
     3601 agagattttc ttcgaccaga gcaagaacgg ctacgccggc tacattgacg gcggagccag
     3661 ccaggaagag ttctacaagt tcatcaagcc catcctggaa aagatggacg gcaccgagga
     3721 actgctcgtg aagctgaaca gagaggacct gctgcggaag cagcggacct tcgacaacgg
     3781 cagcatcccc caccagatcc acctgggaga gctgcacgcc attctgcggc ggcaggaaga
     3841 tttttaccca ttcctgaagg acaaccggga aaagatcgag aagatcctga ccttccgcat
     3901 cccctactac gtgggccctc tggccagggg aaacagcaga ttcgcctgga tgaccagaaa
     3961 gagcgaggaa accatcaccc cctggaactt cgaggaagtg gtggacaagg gcgcttccgc
     4021 ccagagcttc atcgagcgga tgaccaactt cgataagaac ctgcccaacg agaaggtgct
     4081 gcccaagcac agcctgctgt acgagtactt caccgtgtat aacgagctga ccaaagtgaa
     4141 atacgtgacc gagggaatga gaaagcccgc cttcctgagc ggcgagcaga aaaaggccat
     4201 cgtggacctg ctgttcaaga ccaaccggaa agtgaccgtg aagcagctga aagaggacta
     4261 cttcaagaaa atcgagtgct tcgactccgt ggaaatctcc ggcgtggaag atcggttcaa
     4321 cgcctccctg ggcacatacc acgatctgct gaaaattatc aaggacaagg acttcctgga
     4381 caatgaggaa aacgaggaca ttctggaaga tatcgtgctg accctgacac tgtttgagga
     4441 cagagagatg atcgaggaac ggctgaaaac ctatgcccac ctgttcgacg acaaagtgat
     4501 gaagcagctg aagcggcgga gatacaccgg ctggggcagg ctgagccgga agctgatcaa
     4561 cggcatccgg gacaagcagt ccggcaagac aatcctggat ttcctgaagt ccgacggctt
     4621 cgccaacaga aacttcatgc agctgatcca cgacgacagc ctgaccttta aagaggacat
     4681 ccagaaagcc caggtgtccg gccagggcga tagcctgcac gagcacattg ccaatctggc
     4741 cggcagcccc gccattaaga agggcatcct gcagacagtg aaggtggtgg acgagctcgt
     4801 gaaagtgatg ggccggcaca agcccgagaa catcgtgatc gaaatggcca gagagaacca
     4861 gaccacccag aagggacaga agaacagccg cgagagaatg aagcggatcg aagagggcat
     4921 caaagagctg ggcagccaga tcctgaaaga acaccccgtg gaaaacaccc agctgcagaa
     4981 cgagaagctg tacctgtact acctgcagaa tgggcgggat atgtacgtgg accaggaact
     5041 ggacatcaac cggctgtccg actacgatgt ggaccatatc gtgcctcaga gctttctgaa
     5101 ggacgactcc atcgacaaca aggtgctgac cagaagcgac aagaaccggg gcaagagcga
     5161 caacgtgccc tccgaagagg tcgtgaagaa gatgaagaac tactggcggc agctgctgaa
     5221 cgccaagctg attacccaga gaaagttcga caatctgacc aaggccgaga gaggcggcct
     5281 gagcgaactg gataaggccg gcttcatcaa gagacagctg gtggaaaccc ggcagatcac
     5341 aaagcacgtg gcacagatcc tggactcccg gatgaacact aagtacgacg agaatgacaa
     5401 gctgatccgg gaagtgaaag tgatcaccct gaagtccaag ctggtgtccg atttccggaa
     5461 ggatttccag ttttacaaag tgcgcgagat caacaactac caccacgccc acgacgccta
     5521 cctgaacgcc gtcgtgggaa ccgccctgat caaaaagtac cctaagctgg aaagcgagtt
     5581 cgtgtacggc gactacaagg tgtacgacgt gcggaagatg atcgccaaga gcgagcagga
     5641 aatcggcaag gctaccgcca agtacttctt ctacagcaac atcatgaact ttttcaagac
     5701 cgagattacc ctggccaacg gcgagatccg gaagcggcct ctgatcgaga caaacggcga
     5761 aaccggggag atcgtgtggg ataagggccg ggattttgcc accgtgcgga aagtgctgag
     5821 catgccccaa gtgaatatcg tgaaaaagac cgaggtgcag acaggcggct tcagcaaaga
     5881 gtctatcctg cccaagagga acagcgataa gctgatcgcc agaaagaagg actgggaccc
     5941 taagaagtac ggcggcttcg acagccccac cgtggcctat tctgtgctgg tggtggccaa
     6001 agtggaaaag ggcaagtcca agaaactgaa gagtgtgaaa gagctgctgg ggatcaccat
     6061 catggaaaga agcagcttcg agaagaatcc catcgacttt ctggaagcca agggctacaa
     6121 agaagtgaaa aaggacctga tcatcaagct gcctaagtac tccctgttcg agctggaaaa
     6181 cggccggaag agaatgctgg cctctgccgg cgaactgcag aagggaaacg aactggccct
     6241 gccctccaaa tatgtgaact tcctgtacct ggccagccac tatgagaagc tgaagggctc
     6301 ccccgaggat aatgagcaga aacagctgtt tgtggaacag cacaagcact acctggacga
     6361 gatcatcgag cagatcagcg agttctccaa gagagtgatc ctggccgacg ctaatctgga
     6421 caaagtgctg tccgcctaca acaagcaccg ggataagccc atcagagagc aggccgagaa
     6481 tatcatccac ctgtttaccc tgaccaatct gggagcccct gccgccttca agtactttga
     6541 caccaccatc gaccggaaga ggtacaccag caccaaagag gtgctggacg ccaccctgat
     6601 ccaccagagc atcaccggcc tgtacgagac acggatcgac ctgtctcagc tgggaggcga
     6661 caaaaggccg gcggccacga aaaaggccgg ccaggcaaaa aagaaaaagt aagaattcct
     6721 agagctcgct gatcagcctc gactgtgcct tctagttgcc agccatctgt tgtttgcccc
     6781 tcccccgtgc cttccttgac cctggaaggt gccactccca ctgtcctttc ctaataaaat
     6841 gaggaaattg catcgcattg tctgagtagg tgtcattcta ttctgggggg tggggtgggg
     6901 caggacagca agggggagga ttgggaagag aatagcaggc atgctgggga attctagaac
     6961 ccagctttct tgtacaaagt ggtgatcgat tcgacagatc actgaaatgt gtgggcgtgg
     7021 cttaagggtg ggaaagaata tataaggtgg gggtcttatg tagttttgta tctgttttgc
     7081 agcagccgcc gccgccatga gcaccaactc gtttgatgga agcattgtga gctcatattt
     7141 gacaacgcgc atgcccccat gggccggggt gcgtcagaat gtgatgggct ccagcattga
     7201 tggtcgcccc gtcctgcccg caaactctac taccttgacc tacgagaccg tgtctggaac
     7261 gccgttggag actgcagcct ccgccgccgc ttcagccgct gcagccaccg cccgcgggat
     7321 tgtgactgac tttgctttcc tgagcccgct tgcaagcagt gcagcttccc gttcatccgc
     7381 ccgcgatgac aagttgacgg ctcttttggc acaattggat tctttgaccc gggaacttaa
     7441 tgtcgtttct cagcagctgt tggatctgcg ccagcaggtt tctgccctga aggcttcctc
     7501 ccctcccaat gcggtttaaa acataaataa aaaaccagac tctgtttgga tttggatcaa
     7561 gcaagtgtct tgctgtcttt atttaggggt tttgcgcgcg cggtaggccc gggaccagcg
     7621 gtctcggtcg ttgagggtcc tgtgtatttt ttccaggacg tggtaaaggt gactctggat
     7681 gttcagatac atgggcataa gcccgtctct ggggtggagg tagcaccact gcagagcttc
     7741 atgctgcggg gtggtgttgt agatgatcca gtcgtagcag gagcgctggg cgtggtgcct
     7801 aaaaatgtct ttcagtagca agctgattgc caggggcagg cccttggtgt aagtgtttac
     7861 aaagcggtta agctgggatg ggtgcatacg tggggatatg agatgcatct tggactgtat
     7921 ttttaggttg gctatgttcc cagccatatc cctccgggga ttcatgttgt gcagaaccac
     7981 cagcacagtg tatccggtgc acttgggaaa tttgtcatgt agcttagaag gaaatgcgtg
     8041 gaagaacttg gagacgccct tgtgacctcc aagattttcc atgcattcgt ccataatgat
     8101 ggcaatgggc ccacgggcgg cggcctgggc gaagatattt ctgggatcac taacgtcata
     8161 gttgtgttcc aggatgagat cgtcataggc catttttaca aagcgcgggc ggagggtgcc
     8221 agactgcggt ataatggttc catccggccc aggggcgtag ttaccctcac agatttgcat
     8281 ttcccacgct ttgagttcag atggggggat catgtctacc tgcggggcga tgaagaaaac
     8341 ggtttccggg gtaggggaga tcagctggga agaaagcagg ttcctgagca gctgcgactt
     8401 accgcagccg gtgggcccgt aaatcacacc tattaccggc tgcaactggt agttaagaga
     8461 gctgcagctg ccgtcatccc tgagcagggg ggccacttcg ttaagcatgt ccctgactcg
     8521 catgttttcc ctgaccaaat ccgccagaag gcgctcgccg cccagcgata gcagttcttg
     8581 caaggaagca aagtttttca acggtttgag accgtccgcc gtaggcatgc ttttgagcgt
     8641 ttgaccaagc agttccaggc ggtcccacag ctcggtcacc tgctctacgg catctcgatc
     8701 cagcatatct cctcgtttcg cgggttgggg cggctttcgc tgtacggcag tagtcggtgc
     8761 tcgtccagac gggccagggt catgtctttc cacgggcgca gggtcctcgt cagcgtagtc
     8821 tgggtcacgg tgaaggggtg cgctccgggc tgcgcgctgg ccagggtgcg cttgaggctg
     8881 gtcctgctgg tgctgaagcg ctgccggtct tcgccctgcg cgtcggccag gtagcatttg
     8941 accatggtgt catagtccag cccctccgcg gcgtggccct tggcgcgcag cttgcccttg
     9001 gaggaggcgc cgcacgaggg gcagtgcaga cttttgaggg cgtagagctt gggcgcgaga
     9061 aataccgatt ccggggagta ggcatccgcg ccgcaggccc cgcagacggt ctcgcattcc
     9121 acgagccagg tgagctctgg ccgttcgggg tcaaaaacca ggtttccccc atgctttttg
     9181 atgcgtttct tacctctggt ttccatgagc cggtgtccac gctcggtgac gaaaaggctg
     9241 tccgtgtccc cgtatacaga cttgagaggc ctgtcctcga gcggtgttcc gcggtcctcc
     9301 tcgtatagaa actcggacca ctctgagaca aaggctcgcg tccaggccag cacgaaggag
     9361 gctaagtggg aggggtagcg gtcgttgtcc actagggggt ccactcgctc cagggtgtga
     9421 agacacatgt cgccctcttc ggcatcaagg aaggtgattg gtttgtaggt gtaggccacg
     9481 tgaccgggtg ttcctgaagg ggggctataa aagggggtgg gggcgcgttc gtcctcactc
     9541 tcttccgcat cgctgtctgc gagggccagc tgttggggtg agtactccct ctgaaaagcg
     9601 ggcatgactt ctgcgctaag attgtcagtt tccaaaaacg aggaggattt gatattcacc
     9661 tggcccgcgg tgatgccttt gagggtggcc gcatccatct ggtcagaaaa gacaatcttt
     9721 ttgttgtcaa gcttggtggc aaacgacccg tagagggcgt tggacagcaa cttggcgatg
     9781 gagcgcaggg tttggttttt gtcgcgatcg gcgcgctcct tggccgcgat gtttagctgc
     9841 acgtattcgc gcgcaacgca ccgccattcg ggaaagacgg tggtgcgctc gtcgggcacc
     9901 aggtgcacgc gccaaccgcg gttgtgcagg gtgacaaggt caacgctggt ggctacctct
     9961 ccgcgtaggc gctcgttggt ccagcagagg cggccgccct tgcgcgagca gaatggcggt
    10021 agggggtcta gctgcgtctc gtccgggggg tctgcgtcca cggtaaagac cccgggcagc
    10081 aggcgcgcgt cgaagtagtc tatcttgcat ccttgcaagt ctagcgcctg ctgccatgcg
    10141 cgggcggcaa gcgcgcgctc gtatgggttg agtgggggac cccatggcat ggggtgggtg
    10201 agcgcggagg cgtacatgcc gcaaatgtcg taaacgtaga ggggctctct gagtattcca
    10261 agatatgtag ggtagcatct tccaccgcgg atgctggcgc gcacgtaatc gtatagttcg
    10321 tgcgagggag cgaggaggtc gggaccgagg ttgctacggg cgggctgctc tgctcggaag
    10381 actatctgcc tgaagatggc atgtgagttg gatgatatgg ttggacgctg gaagacgttg
    10441 aagctggcgt ctgtgagacc taccgcgtca cgcacgaagg aggcgtagga gtcgcgcagc
    10501 ttgttgacca gctcggcggt gacctgcacg tctagggcgc agtagtccag ggtttccttg
    10561 atgatgtcat acttatcctg tccctttttt ttccacagct cgcggttgag gacaaactct
    10621 tcgcggtctt tccagtactc ttggatcgga aacccgtcgg cctccgaacg gtaagagcct
    10681 agcatgtaga actggttgac ggcctggtag gcgcagcatc ccttttctac gggtagcgcg
    10741 tatgcctgcg cggccttccg gagcgaggtg tgggtgagcg caaaggtgtc cctgaccatg
    10801 actttgaggt actggtattt gaagtcagtg tcgtcgcatc cgccctgctc ccagagcaaa
    10861 aagtccgtgc gctttttgga acgcggattt ggcagggcga aggtgacatc gttgaagagt
    10921 atctttcccg cgcgaggcat aaagttgcgt gtgatgcgga agggtcccgg cacctcggaa
    10981 cggttgttaa ttacctgggc ggcgagcacg atctcgtcaa agccgttgat gttgtggccc
    11041 acaatgtaaa gttccaagaa gcgcgggatg cccttgatgg aaggcaattt tttaagttcc
    11101 tcgtaggtga gctcttcagg ggagctgagc ccgtgctctg aaagggccca gtctgcaaga
    11161 tgagggttgg aagcgacgaa tgagctccac aggtcacggg ccattagcat ttgcaggtgg
    11221 tcgcgaaagg tcctaaactg gcgacctatg gccatttttt ctggggtgat gcagtagaag
    11281 gtaagcgggt cttgttccca gcggtcccat ccaaggttcg cggctaggtc tcgcgcggca
    11341 gtcactagag gctcatctcc gccgaacttc atgaccagca tgaagggcac gagctgcttc
    11401 ccaaaggccc ccatccaagt ataggtctct acatcgtagg tgacaaagag acgctcggtg
    11461 cgaggatgcg agccgatcgg gaagaactgg atctcccgcc accaattgga ggagtggcta
    11521 ttgatgtggt gaaagtagaa gtccctgcga cgggccgaac actcgtgctg gcttttgtaa
    11581 aaacgtgcgc agtactggca gcggtgcacg ggctgtacat cctgcacgag gttgacctga
    11641 cgaccgcgca caaggaagca gagtgggaat ttgagcccct cgcctggcgg gtttggctgg
    11701 tggtcttcta cttcggctgc ttgtccttga ccgtctggct gctcgagggg agttacggtg
    11761 gatcggacca ccacgccgcg cgagcccaaa gtccagatgt ccgcgcgcgg cggtcggagc
    11821 ttgatgacaa catcgcgcag atgggagctg tccatggtct ggagctcccg cggcgtcagg
    11881 tcaggcggga gctcctgcag gtttacctcg catagacggg tcagggcgcg ggctagatcc
    11941 aggtgatacc taatttccag gggctggttg gtggcggcgt cgatggcttg caagaggccg
    12001 catccccgcg gcgcgactac ggtaccgcgc ggcgggcggt gggccgcggg ggtgtccttg
    12061 gatgatgcat ctaaaagcgg tgacgcgggc gagcccccgg aggtaggggg ggctccggac
    12121 ccgccgggag agggggcagg ggcacgtcgg cgccgcgcgc gggcaggagc tggtgctgcg
    12181 cgcgtaggtt gctggcgaac gcgacgacgc ggcggttgat ctcctgaatc tggcgcctct
    12241 gcgtgaagac gacgggcccg gtgagcttga acctgaaaga gagttcgaca gaatcaattt
    12301 cggtgtcgtt gacggcggcc tggcgcaaaa tctcctgcac gtctcctgag ttgtcttgat
    12361 aggcgatctc ggccatgaac tgctcgatct cttcctcctg gagatctccg cgtccggctc
    12421 gctccacggt ggcggcgagg tcgttggaaa tgcgggccat gagctgcgag aaggcgttga
    12481 ggcctccctc gttccagacg cggctgtaga ccacgccccc ttcggcatcg cgggcgcgca
    12541 tgaccacctg cgcgagattg agctccacgt gccgggcgaa gacggcgtag tttcgcaggc
    12601 gctgaaagag gtagttgagg gtggtggcgg tgtgttctgc cacgaagaag tacataaccc
    12661 agcgtcgcaa cgtggattcg ttgatatccc ccaaggcctc aaggcgctcc atggcctcgt
    12721 agaagtccac ggcgaagttg aaaaactggg agttgcgcgc cgacacggtt aactcctcct
    12781 ccagaagacg gatgagctcg gcgacagtgt cgcgcacctc gcgctcaaag gctacagggg
    12841 cctcttcttc ttcttcaatc tcctcttcca taagggcctc cccttcttct tcttctggcg
    12901 gcggtggggg aggggggaca cggcggcgac gacggcgcac cgggaggcgg tcgacaaagc
    12961 gctcgatcat ctccccgcgg cgacggcgca tggtctcggt gacggcgcgg ccgttctcgc
    13021 gggggcgcag ttggaagacg ccgcccgtca tgtcccggtt atgggttggc ggggggctgc
    13081 catgcggcag ggatacggcg ctaacgatgc atctcaacaa ttgttgtgta ggtactccgc
    13141 cgccgaggga cctgagcgag tccgcatcga ccggatcgga aaacctctcg agaaaggcgt
    13201 ctaaccagtc acagtcgcaa ggtaggctga gcaccgtggc gggcggcagc gggcggcggt
    13261 cggggttgtt tctggcggag gtgctgctga tgatgtaatt aaagtaggcg gtcttgagac
    13321 ggcggatggt cgacagaagc accatgtcct tgggtccggc ctgctgaatg cgcaggcggt
    13381 cggccatgcc ccaggcttcg ttttgacatc ggcgcaggtc tttgtagtag tcttgcatga
    13441 gcctttctac cggcacttct tcttctcctt cctcttgtcc tgcatctctt gcatctatcg
    13501 ctgcggcggc ggcggagttt ggccgtaggt ggcgccctct tcctcccatg cgtgtgaccc
    13561 cgaagcccct catcggctga agcagggcta ggtcggcgac aacgcgctcg gctaatatgg
    13621 cctgctgcac ctgcgtgagg gtagactgga agtcatccat gtccacaaag cggtggtatg
    13681 cgcccgtgtt gatggtgtaa gtgcagttgg ccataacgga ccagttaacg gtctggtgac
    13741 ccggctgcga gagctcggtg tacctgagac gcgagtaagc cctcgagtca aatacgtagt
    13801 cgttgcaagt ccgcaccagg tactggtatc ccaccaaaaa gtgcggcggc ggctggcggt
    13861 agaggggcca gcgtagggtg gccggggctc cgggggcgag atcttccaac ataaggcgat
    13921 gatatccgta gatgtacctg gacatccagg tgatgccggc ggcggtggtg gaggcgcgcg
    13981 gaaagtcgcg gacgcggttc cagatgttgc gcagcggcaa aaagtgctcc atggtcggga
    14041 cgctctggcc ggtcaggcgc gcgcaatcgt tgacgctcta gaccgtgcaa aaggagagcc
    14101 tgtaagcggg cactcttccg tggtctggtg gataaattcg caagggtatc atggcggacg
    14161 accggggttc gagccccgta tccggccgtc cgccgtgatc catgcggtta ccgcccgcgt
    14221 gtcgaaccca ggtgtgcgac gtcagacaac gggggagtgc tccttttggc ttccttccag
    14281 gcgcggcggc tgctgcgcta gcttttttgg ccactggccg cgcgcagcgt aagcggttag
    14341 gctggaaagc gaaagcatta agtggctcgc tccctgtagc cggagggtta ttttccaagg
    14401 gttgagtcgc gggacccccg gttcgagtct cggaccggcc ggactgcggc gaacgggggt
    14461 ttgcctcccc gtcatgcaag accccgcttg caaattcctc cggaaacagg gacgagcccc
    14521 ttttttgctt ttcccagatg catccggtgc tgcggcagat gcgcccccct cctcagcagc
    14581 ggcaagagca agagcagcgg cagacatgca gggcaccctc ccctcctcct accgcgtcag
    14641 gaggggcgac atccgcggtt gacgcggcag cagatggtga ttacgaaccc ccgcggcgcc
    14701 gggcccggca ctacctggac ttggaggagg gcgagggcct ggcgcggcta ggagcgccct
    14761 ctcctgagcg gcacccaagg gtgcagctga agcgtgatac gcgtgaggcg tacgtgccgc
    14821 ggcagaacct gtttcgcgac cgcgagggag aggagcccga ggagatgcgg gatcgaaagt
    14881 tccacgcagg gcgcgagctg cggcatggcc tgaatcgcga gcggttgctg cgcgaggagg
    14941 actttgagcc cgacgcgcga accgggatta gtcccgcgcg cgcacacgtg gcggccgccg
    15001 acctggtaac cgcatacgag cagacggtga accaggagat taactttcaa aaaagcttta
    15061 acaaccacgt gcgtacgctt gtggcgcgcg aggaggtggc tataggactg atgcatctgt
    15121 gggactttgt aagcgcgctg gagcaaaacc caaatagcaa gccgctcatg gcgcagctgt
    15181 tccttatagt gcagcacagc agggacaacg aggcattcag ggatgcgctg ctaaacatag
    15241 tagagcccga gggccgctgg ctgctcgatt tgataaacat cctgcagagc atagtggtgc
    15301 aggagcgcag cttgagcctg gctgacaagg tggccgccat caactattcc atgcttagcc
    15361 tgggcaagtt ttacgcccgc aagatatacc atacccctta cgttcccata gacaaggagg
    15421 taaagatcga ggggttctac atgcgcatgg cgctgaaggt gcttaccttg agcgacgacc
    15481 tgggcgttta tcgcaacgag cgcatccaca aggccgtgag cgtgagccgg cggcgcgagc
    15541 tcagcgaccg cgagctgatg cacagcctgc aaagggccct ggctggcacg ggcagcggcg
    15601 atagagaggc cgagtcctac tttgacgcgg gcgctgacct gcgctgggcc ccaagccgac
    15661 gcgccctgga ggcagctggg gccggacctg ggctggcggt ggcacccgcg cgcgctggca
    15721 acgtcggcgg cgtggaggaa tatgacgagg acgatgagta cgagccagag gacggcgagt
    15781 actaagcggt gatgtttctg atcagatgat gcaagacgca acggacccgg cggtgcgggc
    15841 ggcgctgcag agccagccgt ccggccttaa ctccacggac gactggcgcc aggtcatgga
    15901 ccgcatcatg tcgctgactg cgcgcaatcc tgacgcgttc cggcagcagc cgcaggccaa
    15961 ccggctctcc gcaattctgg aagcggtggt cccggcgcgc gcaaacccca cgcacgagaa
    16021 ggtgctggcg atcgtaaacg cgctggccga aaacagggcc atccggcccg acgaggccgg
    16081 cctggtctac gacgcgctgc ttcagcgcgt ggctcgttac aacagcggca acgtgcagac
    16141 caacctggac cggctggtgg gggatgtgcg cgaggccgtg gcgcagcgtg agcgcgcgca
    16201 gcagcagggc aacctgggct ccatggttgc actaaacgcc ttcctgagta cacagcccgc
    16261 caacgtgccg cggggacagg aggactacac caactttgtg agcgcactgc ggctaatggt
    16321 gactgagaca ccgcaaagtg aggtgtacca gtctgggcca gactattttt tccagaccag
    16381 tagacaaggc ctgcagaccg taaacctgag ccaggctttc aaaaacttgc aggggctgtg
    16441 gggggtgcgg gctcccacag gcgaccgcgc gaccgtgtct agcttgctga cgcccaactc
    16501 gcgcctgttg ctgctgctaa tagcgccctt cacggacagt ggcagcgtgt cccgggacac
    16561 atacctaggt cacttgctga cactgtaccg cgaggccata ggtcaggcgc atgtggacga
    16621 gcatactttc caggagatta caagtgtcag ccgcgcgctg gggcaggagg acacgggcag
    16681 cctggaggca accctaaact acctgctgac caaccggcgg cagaagatcc cctcgttgca
    16741 cagtttaaac agcgaggagg agcgcatttt gcgctacgtg cagcagagcg tgagccttaa
    16801 cctgatgcgc gacggggtaa cgcccagcgt ggcgctggac atgaccgcgc gcaacatgga
    16861 accgggcatg tatgcctcaa accggccgtt tatcaaccgc ctaatggact acttgcatcg
    16921 cgcggccgcc gtgaaccccg agtatttcac caatgccatc ttgaacccgc actggctacc
    16981 gccccctggt ttctacaccg ggggattcga ggtgcccgag ggtaacgatg gattcctctg
    17041 ggacgacata gacgacagcg tgttttcccc gcaaccgcag accctgctag agttgcaaca
    17101 gcgcgagcag gcagaggcgg cgctgcgaaa ggaaagcttc cgcaggccaa gcagcttgtc
    17161 cgatctaggc gctgcggccc cgcggtcaga tgctagtagc ccatttccaa gcttgatagg
    17221 gtctcttacc agcactcgca ccacccgccc gcgcctgctg ggcgaggagg agtacctaaa
    17281 caactcgctg ctgcagccgc agcgcgaaaa aaacctgcct ccggcatttc ccaacaacgg
    17341 gatagagagc ctagtggaca agatgagtag atggaagacg tacgcgcagg agcacaggga
    17401 cgtgccaggc ccgcgcccgc ccacccgtcg tcaaaggcac gaccgtcagc ggggtctggt
    17461 gtgggaggac gatgactcgg cagacgacag cagcgtcctg gatttgggag ggagtggcaa
    17521 cccgtttgcg caccttcgcc ccaggctggg gagaatgttt taaaaaaaaa aaaagcatga
    17581 tgcaaaataa aaaactcacc aaggccatgg caccgagcgt tggttttctt gtattcccct
    17641 tagtatgcgg cgcgcggcga tgtatgagga aggtcctcct ccctcctacg agagtgtggt
    17701 gagcgcggcg ccagtggcgg cggcgctggg ttctcccttc gatgctcccc tggacccgcc
    17761 gtttgtgcct ccgcggtacc tgcggcctac cggggggaga aacagcatcc gttactctga
    17821 gttggcaccc ctattcgaca ccacccgtgt gtacctggtg gacaacaagt caacggatgt
    17881 ggcatccctg aactaccaga acgaccacag caactttctg accacggtca ttcaaaacaa
    17941 tgactacagc ccgggggagg caagcacaca gaccatcaat cttgacgacc ggtcgcactg
    18001 gggcggcgac ctgaaaacca tcctgcatac caacatgcca aatgtgaacg agttcatgtt
    18061 taccaataag tttaaggcgc gggtgatggt gtcgcgcttg cctactaagg acaatcaggt
    18121 ggagctgaaa tacgagtggg tggagttcac gctgcccgag ggcaactact ccgagaccat
    18181 gaccatagac cttatgaaca acgcgatcgt ggagcactac ttgaaagtgg gcagacagaa
    18241 cggggttctg gaaagcgaca tcggggtaaa gtttgacacc cgcaacttca gactggggtt
    18301 tgaccccgtc actggtcttg tcatgcctgg ggtatataca aacgaagcct tccatccaga
    18361 catcattttg ctgccaggat gcggggtgga cttcacccac agccgcctga gcaacttgtt
    18421 gggcatccgc aagcggcaac ccttccagga gggctttagg atcacctacg atgatctgga
    18481 gggtggtaac attcccgcac tgttggatgt ggacgcctac caggcgagct tgaaagatga
    18541 caccgaacag ggcgggggtg gcgcaggcgg cagcaacagc agtggcagcg gcgcggaaga
    18601 gaactccaac gcggcagccg cggcaatgca gccggtggag gacatgaacg atcatgccat
    18661 tcgcggcgac acctttgcca cacgggctga ggagaagcgc gctgaggccg aagcagcggc
    18721 cgaagctgcc gcccccgctg cgcaacccga ggtcgagaag cctcagaaga aaccggtgat
    18781 caaacccctg acagaggaca gcaagaaacg cagttacaac ctaataagca atgacagcac
    18841 cttcacccag taccgcagct ggtaccttgc atacaactac ggcgaccctc agaccggaat
    18901 ccgctcatgg accctgcttt gcactcctga cgtaacctgc ggctcggagc aggtctactg
    18961 gtcgttgcca gacatgatgc aagaccccgt gaccttccgc tccacgcgcc agatcagcaa
    19021 ctttccggtg gtgggcgccg agctgttgcc cgtgcactcc aagagcttct acaacgacca
    19081 ggccgtctac tcccaactca tccgccagtt tacctctctg acccacgtgt tcaatcgctt
    19141 tcccgagaac cagattttgg cgcgcccgcc agcccccacc atcaccaccg tcagtgaaaa
    19201 cgttcctgct ctcacagatc acgggacgct accgctgcgc aacagcatcg gaggagtcca
    19261 gcgagtgacc attactgacg ccagacgccg cacctgcccc tacgtttaca aggccctggg
    19321 catagtctcg ccgcgcgtcc tatcgagccg cactttttga gcaagcatgt ccatccttat
    19381 atcgcccagc aataacacag gctggggcct gcgcttccca agcaagatgt ttggcggggc
    19441 caagaagcgc tccgaccaac acccagtgcg cgtgcgcggg cactaccgcg cgccctgggg
    19501 cgcgcacaaa cgcggccgca ctgggcgcac caccgtcgat gacgccatcg acgcggtggt
    19561 ggaggaggcg cgcaactaca cgcccacgcc gccaccagtg tccacagtgg acgcggccat
    19621 tcagaccgtg gtgcgcggag cccggcgcta tgctaaaatg aagagacggc ggaggcgcgt
    19681 agcacgtcgc caccgccgcc gacccggcac tgccgcccaa cgcgcggcgg cggccctgct
    19741 taaccgcgca cgtcgcaccg gccgacgggc ggccatgcgg gccgctcgaa ggctggccgc
    19801 gggtattgtc actgtgcccc ccaggtccag gcgacgagcg gccgccgcag cagccgcggc
    19861 cattagtgct atgactcagg gtcgcagggg caacgtgtat tgggtgcgcg actcggttag
    19921 cggcctgcgc gtgcccgtgc gcacccgccc cccgcgcaac tagattgcaa gaaaaaacta
    19981 cttagactcg tactgttgta tgtatccagc ggcggcggcg cgcaacgaag ctatgtccaa
    20041 gcgcaaaatc aaagaagaga tgctccaggt catcgcgccg gagatctatg gccccccgaa
    20101 gaaggaagag caggattaca agccccgaaa gctaaagcgg gtcaaaaaga aaaagaaaga
    20161 tgatgatgat gaacttgacg acgaggtgga actgctgcac gctaccgcgc ccaggcgacg
    20221 ggtacagtgg aaaggtcgac gcgtaaaacg tgttttgcga cccggcacca ccgtagtctt
    20281 tacgcccggt gagcgctcca cccgcaccta caagcgcgtg tatgatgagg tgtacggcga
    20341 cgaggacctg cttgagcagg ccaacgagcg cctcggggag tttgcctacg gaaagcggca
    20401 taaggacatg ctggcgttgc cgctggacga gggcaaccca acacctagcc taaagcccgt
    20461 aacactgcag caggtgctgc ccgcgcttgc accgtccgaa gaaaagcgcg gcctaaagcg
    20521 cgagtctggt gacttggcac ccaccgtgca gctgatggta cccaagcgcc agcgactgga
    20581 agatgtcttg gaaaaaatga ccgtggaacc tgggctggag cccgaggtcc gcgtgcggcc
    20641 aatcaagcag gtggcgccgg gactgggcgt gcagaccgtg gacgttcaga tacccactac
    20701 cagtagcacc agtattgcca ccgccacaga gggcatggag acacaaacgt ccccggttgc
    20761 ctcagcggtg gcggatgccg cggtgcaggc ggtcgctgcg gccgcgtcca agacctctac
    20821 ggaggtgcaa acggacccgt ggatgtttcg cgtttcagcc ccccggcgcc cgcgccgttc
    20881 gaggaagtac ggcgccgcca gcgcgctact gcccgaatat gccctacatc cttccattgc
    20941 gcctaccccc ggctatcgtg gctacaccta ccgccccaga agacgagcaa ctacccgacg
    21001 ccgaaccacc actggaaccc gccgccgccg tcgccgtcgc cagcccgtgc tggccccgat
    21061 ttccgtgcgc agggtggctc gcgaaggagg caggaccctg gtgctgccaa cagcgcgcta
    21121 ccaccccagc atcgtttaaa agccggtctt tgtggttctt gcagatatgg ccctcacctg
    21181 ccgcctccgt ttcccggtgc cgggattccg aggaagaatg caccgtagga ggggcatggc
    21241 cggccacggc ctgacgggcg gcatgcgtcg tgcgcaccac cggcggcggc gcgcgtcgca
    21301 ccgtcgcatg cgcggcggta tcctgcccct ccttattcca ctgatcgccg cggcgattgg
    21361 cgccgtgccc ggaattgcat ccgtggcctt gcaggcgcag agacactgat taaaaacaag
    21421 ttgcatgtgg aaaaatcaaa ataaaaagtc tggactctca cgctcgcttg gtcctgtaac
    21481 tattttgtag aatggaagac atcaactttg cgtctctggc cccgcgacac ggctcgcgcc
    21541 cgttcatggg aaactggcaa gatatcggca ccagcaatat gagcggtggc gccttcagct
    21601 ggggctcgct gtggagcggc attaaaaatt tcggttccac cgttaagaac tatggcagca
    21661 aggcctggaa cagcagcaca ggccagatgc tgagggataa gttgaaagag caaaatttcc
    21721 aacaaaaggt ggtagatggc ctggcctctg gcattagcgg ggtggtggac ctggccaacc
    21781 aggcagtgca aaataagatt aacagtaagc ttgatccccg ccctcccgta gaggagcctc
    21841 caccggccgt ggagacagtg tctccagagg ggcgtggcga aaagcgtccg cgccccgaca
    21901 gggaagaaac tctggtgacg caaatagacg agcctccctc gtacgaggag gcactaaagc
    21961 aaggcctgcc caccacccgt cccatcgcgc ccatggctac cggagtgctg ggccagcaca
    22021 cacccgtaac gctggacctg cctccccccg ccgacaccca gcagaaacct gtgctgccag
    22081 gcccgaccgc cgttgttgta acccgtccta gccgcgcgtc cctgcgccgc gccgccagcg
    22141 gtccgcgatc gttgcggccc gtagccagtg gcaactggca aagcacactg aacagcatcg
    22201 tgggtctggg ggtgcaatcc ctgaagcgcc gacgatgctt ctgatagcta acgtgtcgta
    22261 tgtgtgtcat gtatgcgtcc atgtcgccgc cagaggagct gctgagccgc cgcgcgcccg
    22321 ctttccaaga tggctacccc ttcgatgatg ccgcagtggt cttacatgca catctcgggc
    22381 caggacgcct cggagtacct gagccccggg ctggtgcagt ttgcccgcgc caccgagacg
    22441 tacttcagcc tgaataacaa gtttagaaac cccacggtgg cgcctacgca cgacgtgacc
    22501 acagaccggt cccagcgttt gacgctgcgg ttcatccctg tggaccgtga ggatactgcg
    22561 tactcgtaca aggcgcggtt caccctagct gtgggtgata accgtgtgct ggacatggct
    22621 tccacgtact ttgacatccg cggcgtgctg gacaggggcc ctacttttaa gccctactct
    22681 ggcactgcct acaacgccct ggctcccaag ggtgccccaa atccttgcga atgggatgaa
    22741 gctgctactg ctcttgaaat aaacctagaa gaagaggacg atgacaacga agacgaagta
    22801 gacgagcaag ctgagcagca aaaaactcac gtatttgggc aggcgcctta ttctggtata
    22861 aatattacaa aggagggtat tcaaataggt gtcgaaggtc aaacacctaa atatgccgat
    22921 aaaacatttc aacctgaacc tcaaatagga gaatctcagt ggtacgaaac agaaattaat
    22981 catgcagctg ggagagtcct aaaaaagact accccaatga aaccatgtta cggttcatat
    23041 gcaaaaccca caaatgaaaa tggagggcaa ggcattcttg taaagcaaca aaatggaaag
    23101 ctagaaagtc aagtggaaat gcaatttttc tcaactactg aggcagccgc aggcaatggt
    23161 gataacttga ctcctaaagt ggtattgtac agtgaagatg tagatataga aaccccagac
    23221 actcatattt cttacatgcc cactattaag gaaggtaact cacgagaact aatgggccaa
    23281 caatctatgc ccaacaggcc taattacatt gcttttaggg acaattttat tggtctaatg
    23341 tattacaaca gcacgggtaa tatgggtgtt ctggcgggcc aagcatcgca gttgaatgct
    23401 gttgtagatt tgcaagacag aaacacagag ctttcatacc agcttttgct tgattccatt
    23461 ggtgatagaa ccaggtactt ttctatgtgg aatcaggctg ttgacagcta tgatccagat
    23521 gttagaatta ttgaaaatca tggaactgaa gatgaacttc caaattactg ctttccactg
    23581 ggaggtgtga ttaatacaga gactcttacc aaggtaaaac ctaaaacagg tcaggaaaat
    23641 ggatgggaaa aagatgctac agaattttca gataaaaatg aaataagagt tggaaataat
    23701 tttgccatgg aaatcaatct aaatgccaac ctgtggagaa atttcctgta ctccaacata
    23761 gcgctgtatt tgcccgacaa gctaaagtac agtccttcca acgtaaaaat ttctgataac
    23821 ccaaacacct acgactacat gaacaagcga gtggtggctc ccgggctagt ggactgctac
    23881 attaaccttg gagcacgctg gtcccttgac tatatggaca acgtcaaccc atttaaccac
    23941 caccgcaatg ctggcctgcg ctaccgctca atgttgctgg gcaatggtcg ctatgtgccc
    24001 ttccacatcc aggtgcctca gaagttcttt gccattaaaa acctccttct cctgccgggc
    24061 tcatacacct acgagtggaa cttcaggaag gatgttaaca tggttctgca gagctcccta
    24121 ggaaatgacc taagggttga cggagccagc attaagtttg atagcatttg cctttacgcc
    24181 accttcttcc ccatggccca caacaccgcc tccacgcttg aggccatgct tagaaacgac
    24241 accaacgacc agtcctttaa cgactatctc tccgccgcca acatgctcta ccctataccc
    24301 gccaacgcta ccaacgtgcc catatccatc ccctcccgca actgggcggc tttccgcggc
    24361 tgggccttca cgcgccttaa gactaaggaa accccatcac tgggctcggg ctacgaccct
    24421 tattacacct actctggctc tataccctac ctagatggaa ccttttacct caaccacacc
    24481 tttaagaagg tggccattac ctttgactct tctgtcagct ggcctggcaa tgaccgcctg
    24541 cttaccccca acgagtttga aattaagcgc tcagttgacg gggagggtta caacgttgcc
    24601 cagtgtaaca tgaccaaaga ctggttcctg gtacaaatgc tagctaacta taacattggc
    24661 taccagggct tctatatccc agagagctac aaggaccgca tgtactcctt ctttagaaac
    24721 ttccagccca tgagccgtca ggtggtggat gatactaaat acaaggacta ccaacaggtg
    24781 ggcatcctac accaacacaa caactctgga tttgttggct accttgcccc caccatgcgc
    24841 gaaggacagg cctaccctgc taacttcccc tatccgctta taggcaagac cgcagttgac
    24901 agcattaccc agaaaaagtt tctttgcgat cgcacccttt ggcgcatccc attctccagt
    24961 aactttatgt ccatgggcgc actcacagac ctgggccaaa accttctcta cgccaactcc
    25021 gcccacgcgc tagacatgac ttttgaggtg gatcccatgg acgagcccac ccttctttat
    25081 gttttgtttg aagtctttga cgtggtccgt gtgcaccagc cgcaccgcgg cgtcatcgaa
    25141 accgtgtacc tgcgcacgcc cttctcggcc ggcaacgcca caacataaag aagcaagcaa
    25201 catcaacaac agctgccgcc atgggctcca gtgagcagga actgaaagcc attgtcaaag
    25261 atcttggttg tgggccatat tttttgggca cctatgacaa gcgctttcca ggctttgttt
    25321 ctccacacaa gctcgcctgc gccatagtca atacggccgg tcgcgagact gggggcgtac
    25381 actggatggc ctttgcctgg aacccgcact caaaaacatg ctacctcttt gagccctttg
    25441 gcttttctga ccagcgactc aagcaggttt accagtttga gtacgagtca ctcctgcgcc
    25501 gtagcgccat tgcttcttcc cccgaccgct gtataacgct ggaaaagtcc acccaaagcg
    25561 tacaggggcc caactcggcc gcctgtggac tattctgctg catgtttctc cacgcctttg
    25621 ccaactggcc ccaaactccc atggatcaca accccaccat gaaccttatt accggggtac
    25681 ccaactccat gctcaacagt ccccaggtac agcccaccct gcgtcgcaac caggaacagc
    25741 tctacagctt cctggagcgc cactcgccct acttccgcag ccacagtgcg cagattagga
    25801 gcgccacttc tttttgtcac ttgaaaaaca tgtaaaaata atgtactaga gacactttca
    25861 ataaaggcaa atgcttttat ttgtacactc tcgggtgatt atttaccccc acccttgccg
    25921 tctgcgccgt ttaaaaatca aaggggttct gccgcgcatc gctatgcgcc actggcaggg
    25981 acacgttgcg atactggtgt ttagtgctcc acttaaactc aggcacaacc atccgcggca
    26041 gctcggtgaa gttttcactc cacaggctgc gcaccatcac caacgcgttt agcaggtcgg
    26101 gcgccgatat cttgaagtcg cagttggggc ctccgccctg cgcgcgcgag ttgcgataca
    26161 cagggttgca gcactggaac actatcagcg ccgggtggtg cacgctggcc agcacgctct
    26221 tgtcggagat cagatccgcg tccaggtcct ccgcgttgct cagggcgaac ggagtcaact
    26281 ttggtagctg ccttcccaaa aagggcgcgt gcccaggctt tgagttgcac tcgcaccgta
    26341 gtggcatcaa aaggtgaccg tgcccggtct gggcgttagg atacagcgcc tgcataaaag
    26401 ccttgatctg cttaaaagcc acctgagcct ttgcgccttc agagaagaac atgccgcaag
    26461 acttgccgga aaactgattg gccggacagg ccgcgtcgtg cacgcagcac cttgcgtcgg
    26521 tgttggagat ctgcaccaca tttcggcccc accggttctt cacgatcttg gccttgctag
    26581 actgctcctt cagcgcgcgc tgcccgtttt cgctcgtcac atccatttca atcacgtgct
    26641 ccttatttat cataatgctt ccgtgtagac acttaagctc gccttcgatc tcagcgcagc
    26701 ggtgcagcca caacgcgcag cccgtgggct cgtgatgctt gtaggtcacc tctgcaaacg
    26761 actgcaggta cgcctgcagg aatcgcccca tcatcgtcac aaaggtcttg ttgctggtga
    26821 aggtcagctg caacccgcgg tgctcctcgt tcagccaggt cttgcatacg gccgccagag
    26881 cttccacttg gtcaggcagt agtttgaagt tcgcctttag atcgttatcc acgtggtact
    26941 tgtccatcag cgcgcgcgca gcctccatgc ccttctccca cgcagacacg atcggcacac
    27001 tcagcgggtt catcaccgta atttcacttt ccgcttcgct gggctcttcc tcttcctctt
    27061 gcgtccgcat accacgcgcc actgggtcgt cttcattcag ccgccgcact gtgcgcttac
    27121 ctcctttgcc atgcttgatt agcaccggtg ggttgctgaa acccaccatt tgtagcgcca
    27181 catcttctct ttcttcctcg ctgtccacga ttacctctgg tgatggcggg cgctcgggct
    27241 tgggagaagg gcgcttcttt ttcttcttgg gcgcaatggc caaatccgcc gccgaggtcg
    27301 atggccgcgg gctgggtgtg cgcggcacca gcgcgtcttg tgatgagtct tcctcgtcct
    27361 cggactcgat acgccgcctc atccgctttt ttgggggcgc ccggggaggc ggcggcgacg
    27421 gggacgggga cgacacgtcc tccatggttg ggggacgtcg cgccgcaccg cgtccgcgct
    27481 cgggggtggt ttcgcgctgc tcctcttccc gactggccat ttccttctcc tataggcaga
    27541 aaaagatcat ggagtcagtc gagaagaagg acagcctaac cgccccctct gagttcgcca
    27601 ccaccgcctc caccgatgcc gccaacgcgc ctaccacctt ccccgtcgag gcacccccgc
    27661 ttgaggagga ggaagtgatt atcgagcagg acccaggttt tgtaagcgaa gacgacgagg
    27721 accgctcagt accaacagag gataaaaagc aagaccagga caacgcagag gcaaacgagg
    27781 aacaagtcgg gcggggggac gaaaggcatg gcgactacct agatgtggga gacgacgtgc
    27841 tgttgaagca tctgcagcgc cagtgcgcca ttatctgcga cgcgttgcaa gagcgcagcg
    27901 atgtgcccct cgccatagcg gatgtcagcc ttgcctacga acgccaccta ttctcaccgc
    27961 gcgtaccccc caaacgccaa gaaaacggca catgcgagcc caacccgcgc ctcaacttct
    28021 accccgtatt tgccgtgcca gaggtgcttg ccacctatca catctttttc caaaactgca
    28081 agatacccct atcctgccgt gccaaccgca gccgagcgga caagcagctg gccttgcggc
    28141 agggcgctgt catacctgat atcgcctcgc tcaacgaagt gccaaaaatc tttgagggtc
    28201 ttggacgcga cgagaagcgc gcggcaaacg ctctgcaaca ggaaaacagc gaaaatgaaa
    28261 gtcactctgg agtgttggtg gaactcgagg gtgacaacgc gcgcctagcc gtactaaaac
    28321 gcagcatcga ggtcacccac tttgcctacc cggcacttaa cctacccccc aaggtcatga
    28381 gcacagtcat gagtgagctg atcgtgcgcc gtgcgcagcc cctggagagg gatgcaaatt
    28441 tgcaagaaca aacagaggag ggcctacccg cagttggcga cgagcagcta gcgcgctggc
    28501 ttcaaacgcg cgagcctgcc gacttggagg agcgacgcaa actaatgatg gccgcagtgc
    28561 tcgttaccgt ggagcttgag tgcatgcagc ggttctttgc tgacccggag atgcagcgca
    28621 agctagagga aacattgcac tacacctttc gacagggcta cgtacgccag gcctgcaaga
    28681 tctccaacgt ggagctctgc aacctggtct cctaccttgg aattttgcac gaaaaccgcc
    28741 ttgggcaaaa cgtgcttcat tccacgctca agggcgaggc gcgccgcgac tacgtccgcg
    28801 actgcgttta cttatttcta tgctacacct ggcagacggc catgggcgtt tggcagcagt
    28861 gcttggagga gtgcaacctc aaggagctgc agaaactgct aaagcaaaac ttgaaggacc
    28921 tatggacggc cttcaacgag cgctccgtgg ccgcgcacct ggcggacatc attttccccg
    28981 aacgcctgct taaaaccctg caacagggtc tgccagactt caccagtcaa agcatgttgc
    29041 agaactttag gaactttatc ctagagcgct caggaatctt gcccgccacc tgctgtgcac
    29101 ttcctagcga ctttgtgccc attaagtacc gcgaatgccc tccgccgctt tggggccact
    29161 gctaccttct gcagctagcc aactaccttg cctaccactc tgacataatg gaagacgtga
    29221 gcggtgacgg tctactggag tgtcactgtc gctgcaacct atgcaccccg caccgctccc
    29281 tggtttgcaa ttcgcagctg cttaacgaaa gtcaaattat cggtaccttt gagctgcagg
    29341 gtccctcgcc tgacgaaaag tccgcggctc cggggttgaa actcactccg gggctgtgga
    29401 cgtcggctta ccttcgcaaa tttgtacctg aggactacca cgcccacgag attaggttct
    29461 acgaagacca atcccgcccg cctaatgcgg agcttaccgc ctgcgtcatt acccagggcc
    29521 acattcttgg ccaattgcaa gccatcaaca aagcccgcca agagtttctg ctacgaaagg
    29581 gacggggggt ttacttggac ccccagtccg gcgaggagct caacccaatc cccccgccgc
    29641 cgcagcccta tcagcagcag ccgcgggccc ttgcttccca ggatggcacc caaaaagaag
    29701 ctgcagctgc cgccgccacc cacggacgag gaggaatact gggacagtca ggcagaggag
    29761 gttttggacg aggaggagga ggacatgatg gaagactggg agagcctaga cgaggaagct
    29821 tccgaggtcg aagaggtgtc agacgaaaca ccgtcaccct cggtcgcatt cccctcgccg
    29881 gcgccccaga aatcggcaac cggttccagc atggctacaa cctccgctcc tcaggcgccg
    29941 ccggcactgc ccgttcgccg acccaaccgt agatgggaca ccactggaac cagggccggt
    30001 aagtccaagc agccgccgcc gttagcccaa gagcaacaac agcgccaagg ctaccgctca
    30061 tggcgcgggc acaagaacgc catagttgct tgcttgcaag actgtggggg caacatctcc
    30121 ttcgcccgcc gctttcttct ctaccatcac ggcgtggcct tcccccgtaa catcctgcat
    30181 tactaccgtc atctctacag cccatactgc accggcggca gcggcagcaa cagcagcggc
    30241 cacacagaag caaaggcgac cggatagcaa gactctgaca aagcccaaga aatccacagc
    30301 ggcggcagca gcaggaggag gagcgctgcg tctggcgccc aacgaacccg tatcgacccg
    30361 cgagcttaga aacaggattt ttcccactct gtatgctata tttcaacaga gcaggggcca
    30421 agaacaagag ctgaaaataa aaaacaggtc tctgcgatcc ctcacccgca gctgcctgta
    30481 tcacaaaagc gaagatcagc ttcggcgcac gctggaagac gcggaggctc tcttcagtaa
    30541 atactgcgcg ctgactctta aggactagtt tcgcgccctt tctcaaattt aagcgcgaaa
    30601 actacgtcat ctccagcggc cacacccggc gccagcacct gttgtcagcg ccattatgag
    30661 caaggaaatt cccacgccct acatgtggag ttaccagcca caaatgggac ttgcggctgg
    30721 agctgcccaa gactactcaa cccgaataaa ctacatgagc gcgggacccc acatgatatc
    30781 ccgggtcaac ggaatacgcg cccaccgaaa ccgaattctc ctggaacagg cggctattac
    30841 caccacacct cgtaataacc ttaatccccg tagttggccc gctgccctgg tgtaccagga
    30901 aagtcccgct cccaccactg tggtacttcc cagagacgcc caggccgaag ttcagatgac
    30961 taactcaggg gcgcagcttg cgggcggctt tcgtcacagg gtgcggtcgc ccgggcaggg
    31021 tataactcac ctgacaatca gagggcgagg tattcagctc aacgacgagt cggtgagctc
    31081 ctcgcttggt ctccgtccgg acgggacatt tcagatcggc ggcgccggcc gctcttcatt
    31141 cacgcctcgt caggcaatcc taactctgca gacctcgtcc tctgagccgc gctctggagg
    31201 cattggaact ctgcaattta ttgaggagtt tgtgccatcg gtctacttta accccttctc
    31261 gggacctccc ggccactatc cggatcaatt tattcctaac tttgacgcgg taaaggactc
    31321 ggcggacggc tacgactgaa tgttaagtgg agaggcagag caactgcgcc tgaaacacct
    31381 ggtccactgt cgccgccaca agtgctttgc ccgcgactcc ggtgagtttt gctactttga
    31441 attgcccgag gatcatatcg agggcccggc gcacggcgtc cggcttaccg cccagggaga
    31501 gcttgcccgt agcctgattc gggagtttac ccagcgcccc ctgctagttg agcgggacag
    31561 gggaccctgt gttctcactg tgatttgcaa ctgtcctaac cctggattac atcaagatct
    31621 ttgttgccat ctctgtgctg agtataataa atacagaaat taaaatatac tggggctcct
    31681 atcgccatcc tgtaaacgcc accgtcttca cccgcccaag caaaccaagg cgaaccttac
    31741 ctggtacttt taacatctct ccctctgtga tttacaacag tttcaaccca gacggagtga
    31801 gtctacgaga gaacctctcc gagctcagct actccatcag aaaaaacacc accctcctta
    31861 cctgccggga acgtacgagt gcgtcaccgg ccgctgcacc acacctaccg cctgaccgta
    31921 aaccagactt tttccggaca gacctcaata actctgttta ccagaacagg aggtgagctt
    31981 agaaaaccct tagggtatta ggccaaaggc gcagctactg tggggtttat gaacaattca
    32041 agcaactcta cgggctattc taattcaggt ttctctagaa atggacggaa ttattacaga
    32101 gcagcgcctg ctagaaagac gcagggcagc ggccgagcaa cagcgcatga atcaagagct
    32161 ccaagacatg gttaacttgc accagtgcaa aaggggtatc ttttgtctgg taaagcaggc
    32221 caaagtcacc tacgacagta ataccaccgg acaccgcctt agctacaagt tgccaaccaa
    32281 gcgtcagaaa ttggtggtca tggtgggaga aaagcccatt accataactc agcactcggt
    32341 agaaaccgaa ggctgcattc actcaccttg tcaaggacct gaggatctct gcacccttat
    32401 taagaccctg tgcggtctca aagatcttat tccctttaac taataaaaaa aaataataaa
    32461 gcatcactta cttaaaatca gttagcaaat ttctgtccag tttattcagc agcacctcct
    32521 tgccctcctc ccagctctgg tattgcagct tcctcctggc tgcaaacttt ctccacaatc
    32581 taaatggaat gtcagtttcc tcctgttcct gtccatccgc acccactatc ttcatgttgt
    32641 tgcagatgaa gcgcgcaaga ccgtctgaag ataccttcaa ccccgtgtat ccatatgaca
    32701 cggaaaccgg tcctccaact gtgccttttc ttactcctcc ctttgtatcc cccaatgggt
    32761 ttcaagagag tccccctggg gtactctctt tgcgcctatc cgaacctcta gttacctcca
    32821 atggcatgct tgcgctcaaa atgggcaacg gcctctctct ggacgaggcc ggcaacctta
    32881 cctcccaaaa tgtaaccact gtgagcccac ctctcaaaaa aaccaagtca aacataaacc
    32941 tggaaatatc tgcacccctc acagttacct cagaagccct aactgtggct gccgccgcac
    33001 ctctaatggt cgcgggcaac acactcacca tgcaatcaca ggccccgcta accgtgcacg
    33061 actccaaact tagcattgcc acccaaggac ccctcacagt gtcagaagga aagctagccc
    33121 tgcaaacatc aggccccctc accaccaccg atagcagtac ccttactatc actgcctcac
    33181 cccctctaac tactgccact ggtagcttgg gcattgactt gaaagagccc atttatacac
    33241 aaaatggaaa actaggacta aagtacgggg ctcctttgca tgtaacagac gacctaaaca
    33301 ctttgaccgt agcaactggt ccaggtgtga ctattaataa tacttccttg caaactaaag
    33361 ttactggagc cttgggtttt gattcacaag gcaatatgca acttaatgta gcaggaggac
    33421 taaggattga ttctcaaaac agacgcctta tacttgatgt tagttatccg tttgatgctc
    33481 aaaaccaact aaatctaaga ctaggacagg gccctctttt tataaactca gcccacaact
    33541 tggatattaa ctacaacaaa ggcctttact tgtttacagc ttcaaacaat tccaaaaagc
    33601 ttgaggttaa cctaagcact gccaaggggt tgatgtttga cgctacagcc atagccatta
    33661 atgcaggaga tgggcttgaa tttggttcac ctaatgcacc aaacacaaat cccctcaaaa
    33721 caaaaattgg ccatggccta gaatttgatt caaacaaggc tatggttcct aaactaggaa
    33781 ctggccttag ttttgacagc acaggtgcca ttacagtagg aaacaaaaat aatgataagc
    33841 taactttgtg gaccacacca gctccatctc ctaactgtag actaaatgca gagaaagatg
    33901 ctaaactcac tttggtctta acaaaatgtg gcagtcaaat acttgctaca gtttcagttt
    33961 tggctgttaa aggcagtttg gctccaatat ctggaacagt tcaaagtgct catcttatta
    34021 taagatttga cgaaaatgga gtgctactaa acaattcctt cctggaccca gaatattgga
    34081 actttagaaa tggagatctt actgaaggca cagcctatac aaacgctgtt ggatttatgc
    34141 ctaacctatc agcttatcca aaatctcacg gtaaaactgc caaaagtaac attgtcagtc
    34201 aagtttactt aaacggagac aaaactaaac ctgtaacact aaccattaca ctaaacggta
    34261 cacaggaaac aggagacaca actccaagtg catactctat gtcattttca tgggactggt
    34321 ctggccacaa ctacattaat gaaatatttg ccacatcctc ttacactttt tcatacattg
    34381 cccaagaata aagaatcgtt tgtgttatgt ttcaacgtgt ttatttttca attgcagaaa
    34441 atttcgaatc atttttcatt cagtagtata gccccaccac cacatagctt atacagatca
    34501 ccgtacctta atcaaactca cagaacccta gtattcaacc tgccacctcc ctcccaacac
    34561 acagagtaca cagtcctttc tccccggctg gccttaaaaa gcatcatatc atgggtaaca
    34621 gacatattct taggtgttat attccacacg gtttcctgtc gagccaaacg ctcatcagtg
    34681 atattaataa actccccggg cagctcactt aagttcatgt cgctgtccag ctgctgagcc
    34741 acaggctgct gtccaacttg cggttgctta acgggcggcg aaggagaagt ccacgcctac
    34801 atgggggtag agtcataatc gtgcatcagg atagggcggt ggtgctgcag cagcgcgcga
    34861 ataaactgct gccgccgccg ctccgtcctg caggaataca acatggcagt ggtctcctca
    34921 gcgatgattc gcaccgcccg cagcataagg cgccttgtcc tccgggcaca gcagcgcacc
    34981 ctgatctcac ttaaatcagc acagtaactg cagcacagca ccacaatatt gttcaaaatc
    35041 ccacagtgca aggcgctgta tccaaagctc atggcgggga ccacagaacc cacgtggcca
    35101 tcataccaca agcgcaggta gattaagtgg cgacccctca taaacacgct ggacataaac
    35161 attacctctt ttggcatgtt gtaattcacc acctcccggt accatataaa cctctgatta
    35221 aacatggcgc catccaccac catcctaaac cagctggcca aaacctgccc gccggctata
    35281 cactgcaggg aaccgggact ggaacaatga cagtggagag cccaggactc gtaaccatgg
    35341 atcatcatgc tcgtcatgat atcaatgttg gcacaacaca ggcacacgtg catacacttc
    35401 ctcaggatta caagctcctc ccgcgttaga accatatccc agggaacaac ccattcctga
    35461 atcagcgtaa atcccacact gcagggaaga cctcgcacgt aactcacgtt gtgcattgtc
    35521 aaagtgttac attcgggcag cagcggatga tcctccagta tggtagcgcg ggtttctgtc
    35581 tcaaaaggag gtagacgatc cctactgtac ggagtgcgcc gagacaaccg agatcgtgtt
    35641 ggtcgtagtg tcatgccaaa tggaacgccg gacgtagtca tatttcctga agcaaaacca
    35701 ggtgcgggcg tgacaaacag atctgcgtct ccggtctcgc cgcttagatc gctctgtgta
    35761 gtagttgtag tatatccact ctctcaaagc atccaggcgc cccctggctt cgggttctat
    35821 gtaaactcct tcatgcgccg ctgccctgat aacatccacc accgcagaat aagccacacc
    35881 cagccaacct acacattcgt tctgcgagtc acacacggga ggagcgggaa gagctggaag
    35941 aaccatgttt ttttttttat tccaaaagat tatccaaaac ctcaaaatga agatctatta
    36001 agtgaacgcg ctcccctccg gtggcgtggt caaactctac agccaaagaa cagataatgg
    36061 catttgtaag atgttgcaca atggcttcca aaaggcaaac ggccctcacg tccaagtgga
    36121 cgtaaaggct aaacccttca gggtgaatct cctctataaa cattccagca ccttcaacca
    36181 tgcccaaata attctcatct cgccaccttc tcaatatatc tctaagcaaa tcccgaatat
    36241 taagtccggc cattgtaaaa atctgctcca gagcgccctc caccttcagc ctcaagcagc
    36301 gaatcatgat tgcaaaaatt caggttcctc acagacctgt ataagattca aaagcggaac
    36361 attaacaaaa ataccgcgat cccgtaggtc ccttcgcagg gccagctgaa cataatcgtg
    36421 caggtctgca cggaccagcg cggccacttc cccgccagga accatgacaa aagaacccac
    36481 actgattatg acacgcatac tcggagctat gctaaccagc gtagccccga tgtaagcttg
    36541 ttgcatgggc ggcgatataa aatgcaaggt gctgctcaaa aaatcaggca aagcctcgcg
    36601 caaaaaagaa agcacatcgt agtcatgctc atgcagataa aggcaggtaa gctccggaac
    36661 caccacagaa aaagacacca tttttctctc aaacatgtct gcgggtttct gcataaacac
    36721 aaaataaaat aacaaaaaaa catttaaaca ttagaagcct gtcttacaac aggaaaaaca
    36781 acccttataa gcataagacg gactacggcc atgccggcgt gaccgtaaaa aaactggtca
    36841 ccgtgattaa aaagcaccac cgacagctcc tcggtcatgt ccggagtcat aatgtaagac
    36901 tcggtaaaca catcaggttg attcacatcg gtcagtgcta aaaagcgacc gaaatagccc
    36961 gggggaatac atacccgcag gcgtagagac aacattacag cccccatagg aggtataaca
    37021 aaattaatag gagagaaaaa cacataaaca cctgaaaaac cctcctgcct aggcaaaata
    37081 gcaccctccc gctccagaac aacatacagc gcttccacag cggcagccat aacagtcagc
    37141 cttaccagta aaaaagaaaa cctattaaaa aaacaccact cgacacggca ccagctcaat
    37201 cagtcacagt gtaaaaaagg gccaagtgca gagcgagtat atataggact aaaaaatgac
    37261 gtaacggtta aagtccacaa aaaacaccca gaaaaccgca cgcgaaccta cgcccagaaa
    37321 cgaaagccaa aaaacccaca acttcctcaa atcgtcactt ccgttttccc acgttacgtc
    37381 acttcccatt ttaagaaaac tacaattccc aacacataca agttactccg ccctaaaacc
    37441 tacgtcaccc gccccgttcc cacgccccgc gccacgtcac aaactccacc ccctcattat
    37501 catattggct tcaatccaaa ataaggtata ttattgatga tgttaattaa tttaaatccg
    37561 catgcgatat cgagctctcc cgggaattcg gatctgcgac gcgaggctgg atggccttcc
    37621 ccattatgat tcttctcgct tccggcggca tcgggatgcc cgcgttgcag gccatgctgt
    37681 ccaggcaggt agatgacgac catcagggac agcttcaagg ccagcaaaag gccaggaacc
    37741 gtaaaaaggc cgcgttgctg gcgtttttcc ataggctccg cccccctgac gagcatcaca
    37801 aaaatcgacg ctcaagtcag aggtggcgaa acccgacagg actataaaga taccaggcgt
    37861 ttccccctgg aagctccctc gtgcgctctc ctgttccgac cctgccgctt accggatacc
    37921 tgtccgcctt tctcccttcg ggaagcgtgg cgctttctca tagctcacgc tgtaggtatc
    37981 tcagttcggt gtaggtcgtt cgctccaagc tgggctgtgt gcacgaaccc cccgttcagc
    38041 ccgaccgctg cgccttatcc ggtaactatc gtcttgagtc caacccggta agacacgact
    38101 tatcgccact ggcagcagcc actggtaaca ggattagcag agcgaggtat gtaggcggtg
    38161 ctacagagtt cttgaagtgg tggcctaact acggctacac tagaaggaca gtatttggta
    38221 tctgcgctct gctgaagcca gttaccttcg gaaaaagagt tggtagctct tgatccggca
    38281 aacaaaccac cgctggtagc ggtggttttt ttgtttgcaa gcagcagatt acgcgcagaa
    38341 aaaaaggatc tcaagaagat cctttgatct tttctacggg gtctgacgct cagtggaacg
    38401 aaaactcacg ttaagggatt ttggtcatga gattatcaaa aaggatcttc acctagatcc
    38461 ttttaaatca atctaaagta tatatgagta aacttggtct gacagttacc aatgcttaat
    38521 cagtgaggca cctatctcag cgatctgtct atttcgttca tccatagttg cctgactccc
    38581 cgtcgtgtag ataactacga tacgggaggg cttaccatct ggccccagtg ctgcaatgat
    38641 accgcgagac ccacgctcac cggctccaga tttatcagca ataaaccagc cagccggaag
    38701 ggccgagcgc agaagtggtc ctgcaacttt atccgcctcc atccagtcta ttaattgttg
    38761 ccgggaagct agagtaagta gttcgccagt taatagtttg cgcaacgttg ttgccattgc
    38821 tacaggcatc gtggtgtcac gctcgtcgtt tggtatggct tcattcagct ccggttccca
    38881 acgatcaagg cgagttacat gatcccccat gttgtgcaaa aaagcggtta gctccttcgg
    38941 tcctccgatc gttgtcagaa gtaagttggc cgcagtgtta tcactcatgg ttatggcagc
    39001 actgcataat tctcttactg tcatgccatc cgtaagatgc ttttctgtga ctggtgagta
    39061 ctcaaccaag tcattctgag aatagtgtat gcggcgaccg agttgctctt gcccggcgtc
    39121 aacacgggat aataccgcgc cacatagcag aactttaaaa gtgctcatca ttggaaaacg
    39181 ttcttcgggg cgaaaactct caaggatctt accgctgttg agatccagtt cgatgtaacc
    39241 cactcgtgca cccaactgat cttcagcatc ttttactttc accagcgttt ctgggtgagc
    39301 aaaaacagga aggcaaaatg ccgcaaaaaa gggaataagg gcgacacgga aatgttgaat
    39361 actcatactc ttcctttttc aatattattg aagcatttat cagggttatt gtctcatgag
    39421 cggatacata tttgaatgta tttagaaaaa taaacaaata ggggttccgc gcacatttcc
    39481 ccgaaaagtg ccacctgacg tctaagaaac cattattatc atgacattaa cctataaaaa
    39541 taggcgtatc acgaggccct ttcgtcttca agaattggat ccgaattccc gggagagctc
    39601 gatatcgcat gcggatttaa attaattaac atcatcaata atatacctta ttttggattg
    39661 aagccaatat gataatgagg gggtggagtt tgtgacgtgg cgcggggcgt gggaacgggg
    39721 cgggtgacgt agtagtgtgg cggaagtgtg atgttgcaag tgtggcggaa cacatgtaag
    39781 cgacggatgt ggcaaaagtg acgtttttgg tgtgcgccgg tgtacacagg aagtgacaat
    39841 tttcgcgcgg ttttaggcgg atgttgtagt aaatttgggc gtaaccgagt aagatttggc
    39901 cattttcgcg ggaaaactga ataagaggaa gtgaaatctg aataattttg tgttactcat
    39961 agcgcgtaat atttgtctag ggccgcgggg actttgaccg tttacgtgga gactcgccca
    40021 ggtgtttttc tcaggtgttt tccgcgttcc gggtcaaagt tggcgtttta ttattatagt
    40081 cagtcgaagc ttggatccgg tacctctaga attctcgagc ggccgctagc gacatcgatc
    40141 acaagttt
//
