LOCUS       sequence-380568-       22422 bp    DNA     circular SYN 15-DEC-2025
DEFINITION  For genome editing (base editing) of Arabidopsis mitochondria, 
            targeted C of RNA editing site of ATP1 by OTP87.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      synthetic DNA construct
  ORGANISM  synthetic DNA construct
REFERENCE   1  (bases 1 to 22422)
  AUTHORS   Nakazato I, Okuno M, Zhou C, Itoh T, Tsutsumi N, Takenaka M, Arimura
            SI
  TITLE     Targeted base editing in the mitochondrial genome of Arabidopsis 
            thaliana.
  JOURNAL   Proc Natl Acad Sci U S A. 2022 May 17;119(20):e2121177119. doi: 
            10.1073/pnas.2121177119. Epub 2022 May 13.
  PUBMED    35561225
REFERENCE   2  (bases 1 to 22422)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Proc Natl 
            Acad Sci U S A."; date: "2022-05-17"; volume: "119(20):e2121177119. 
            doi"; pages: " 10.1073/pnas.2121177119. Epub 2022 May 13"
COMMENT     Sequence Label: mitoTALECD for_atp1_1333NC
FEATURES             Location/Qualifiers
     source          1..22422
                     /mol_type="other DNA"
                     /organism="synthetic DNA construct"
     protein_bind    complement(2246..2270)
                     /gene="mutant version of attB"
                     /label=attB2
                     /bound_moiety="BP Clonase(TM)"
                     /note="recombination site for the Gateway(R) BP reaction"
     CDS             join(2283..2285,2286..2288,2289..2996)
                     /codon_start=1
                     /product="enhanced GFP"
                     /label=EGFP
                     /translation="MVSKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTL
                     KFICTTGKLPVPWPTLVTTLTYGVQCFSRYPDHMKQHDFFKSAMPEGYVQERTIFFKDD
                     GNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQKNGIK
                     VNFKIRHNIEDGSVQLADHYQQNTPIGDGPVLLPDNHYLSTQSALSKDPNEKRDHMVLL
                     EFVTAAGITLGMDELY"
     CDS             join(2283..2285,2286..2288,2289..2996)
                     /codon_start=1
                     /product="the original enhanced GFP (Yang et al., 1996)"
                     /label=EGFP
                     /note="mammalian codon-optimized"
                     /translation="MVSKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTL
                     KFICTTGKLPVPWPTLVTTLTYGVQCFSRYPDHMKQHDFFKSAMPEGYVQERTIFFKDD
                     GNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQKNGIK
                     VNFKIRHNIEDGSVQLADHYQQNTPIGDGPVLLPDNHYLSTQSALSKDPNEKRDHMVLL
                     EFVTAAGITLGMDELY"
     primer_bind     complement(2328..2349)
                     /label=EGFP-N
                     /note="EGFP, reverse primer"
     primer_bind     complement(2589..2608)
                     /label=EXFP-R
                     /note="For distinguishing EGFP variants, reverse primer"
     primer_bind     2936..2957
                     /label=EGFP-C
                     /note="EGFP, forward primer"
     regulatory      3174..3183
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
     promoter        3522..3701
                     /label=NOS promoter
                     /note="nopaline synthase promoter"
     CDS             3735..4529
                     /codon_start=1
                     /gene="aph(3')-II (or nptII)"
                     /product="aminoglycoside phosphotransferase from Tn5"
                     /label=NeoR/KanR
                     /note="confers resistance to neomycin, kanamycin, and G418 
                     (Geneticin(R))"
                     /translation="MIEQDGLHAGSPAAWVERLFGYDWAQQTIGCSDAAVFRLSAQGRP
                     VLFVKTDLSGALNELQDEAARLSWLATTGVPCAAVLDVVTEAGRDWLLLGEVPGQDLLS
                     SHLAPAEKVSIMADAMRRLHTLDPATCPFDHQAKHRIERARTRMEAGLVDQDDLDEEHQ
                     GLAPAELFARLKARMPDGEDLVVTHGDACLPNIMVENGRFSGFIDCGRLGVADRYQDIA
                     LATRDIAEELGGEWADRFLVLYGIAAPDSQRIAFYRLLDEFF"
     primer_bind     complement(3789..3808)
                     /label=Neo-R
                     /note="Neomycin resistance gene, reverse primer"
     primer_bind     4399..4418
                     /label=Neo-F
                     /note="Neomycin resistance gene, forward primer"
     terminator      4569..4821
                     /label=NOS terminator
                     /note="nopaline synthase terminator and poly(A) signal"
     misc_feature    4914..4938
                     /label=LB T-DNA repeat
                     /note="left border repeat from nopaline C58 T-DNA"
     CDS             5459..6250
                     /codon_start=1
                     /gene="aadA"
                     /product="aminoglycoside adenylyltransferase (Murphy, 
                     1985)"
                     /label=SmR
                     /note="confers resistance to spectinomycin and 
                     streptomycin"
                     /translation="MGEAVIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKPH
                     SDIDLLVTVTVRLDETTRRALINDLLETSASPGESEILRAVEVTIVVHDDIIPWRYPAK
                     RELQFGEWQRNDILAGIFEPATIDIDLAILLTKAREHSVALVGPAAEELFDPVPEQDLF
                     EALNETLTLWNSPPDWAGDERNVVLTLSRIWYSAVTGKIAPKDVAADWAMERLPAQYQP
                     VILEARQAYLGQEEDRLASRADQLEEFVHYVKGEITKVVGK"
     rep_origin      6500..7088
                     /direction=RIGHT
                     /label=ori
                     /note="high-copy-number ColE1/pMB1/pBR322/pUC origin of 
                     replication"
     primer_bind     6989..7008
                     /label=pBR322ori-F
                     /note="pBR322 origin, forward primer"
     primer_bind     7242..7259
                     /label=L4440
                     /note="L4440 vector, forward primer"
     misc_feature    7274..7414
                     /label=bom
                     /note="basis of mobility region from pBR322"
     primer_bind     complement(7340..7359)
                     /label=pRS-marker
                     /note="pRS vectors, use to sequence yeast selectable 
                     marker"
     primer_bind     7500..7522
                     /label=pGEX 3'
                     /note="pGEX vectors, reverse primer"
     rep_origin      7758..7952
                     /label=pVS1 oriV
                     /note="origin of replication for the Pseudomonas plasmid 
                     pVS1 (Heeb et al., 2000)"
     CDS             complement(8018..9091)
                     /codon_start=1
                     /product="replication protein from the Pseudomonas plasmid 
                     pVS1 (Heeb et al., 2000)"
                     /label=pVS1 RepA
                     /translation="MSGRKPSGPVQIGAALGDDLVEKLKAAQAAQRQRIEAEARPGESW
                     QAAADRIRKESRQPPAAGAPSIRKPPKGDEQPDFFVPMLYDVGTRDSRSIMDVAVFRLS
                     KRDRRAGEVIRYELPDGHVEVSAGPAGMASVWDYDLVLMAVSHLTESMNRYREGKGDKP
                     GRVFRPHVADVLKFCRRADGGKQKDDLVETCIRLNTTHVAMQRTKKAKNGRLVTVSEGE
                     ALISRYKIVKSETGRPEYIEIELADWMYREITEGKNPDVLTVHPDYFLIDPGIGRFLYR
                     LARRAAGKAEARWLFKTIYERSGSAGEFKKFCFTVRKLIGSNDLPEYDLKEEAGQAGPI
                     LVMRYRNLIEGEASAGS"
     CDS             complement(9520..10149)
                     /codon_start=1
                     /product="stability protein from the Pseudomonas plasmid 
                     pVS1 (Heeb et al., 2000)"
                     /label=pVS1 StaA
                     /translation="MKVIAVLNQKGGSGKTTIATHLARALQLAGADVLLVDSDPQGSAR
                     DWAAVREDQPLTVVGIDRPTIDRDVKAIGRRDFVVIDGAPQAADLAVSAIKAADFVLIP
                     VQPSPYDIWATADLVELVKQRIEVTDGRLQAAFVVSRAIKGTRIGGEVAEALAGYELPI
                     LESRITQRVSYPGTAAAGTTVLESEPEGDAAREVQALAAEIKSKLI"
     misc_feature    11480..11504
                     /label=RB T-DNA repeat
                     /note="right border repeat from nopaline C58 T-DNA"
     protein_bind    13346..13370
                     /gene="mutant version of attB"
                     /label=attB1
                     /bound_moiety="BP Clonase(TM)"
                     /note="recombination site for the Gateway(R) BP reaction"
     CDS             13373..13399
                     /codon_start=1
                     /product="HA (human influenza hemagglutinin) epitope tag"
                     /label=HA
                     /translation="YPYDVPDYA"
     CDS             16085..16336
                     /codon_start=1
                     /product="uracil-DNA glycosylase inhibitor from a Bacillus 
                     subtilis bacteriophage (Mol et al., 1995)"
                     /label=UGI
                     /translation="TNLSDIIEKETGKQLVIQESILMLPEEVEEVIGNKPESDILVHTA
                     YDESTDENVMLLTSDAPEYKPWALVIQDSNGENKIKML"
     protein_bind    complement(16362..16382)
                     /gene="mutant version of attB"
                     /label=attB4
                     /bound_moiety="BP Clonase(TM)"
                     /note="core recombination site for the Gateway(R) BP 
                     reaction"
     terminator      16387..16635
                     /label=HSP terminator
                     /note="efficient transcription terminator from the 
                     Arabidopsis thaliana heat shock protein 18.2 gene (Nagaya 
                     et al., 2010)"
     protein_bind    18967..18987
                     /gene="mutant version of attB"
                     /label=attB3
                     /bound_moiety="BP Clonase(TM)"
                     /note="core recombination site for the Gateway(R) BP 
                     reaction"
     CDS             18990..19034
                     /codon_start=1
                     /product="affinity and epitope tag derived from pancreatic 
                     ribonuclease A"
                     /label=S-Tag
                     /translation="KETAAAKFERQHMDS"
     CDS             21873..22124
                     /codon_start=1
                     /product="uracil-DNA glycosylase inhibitor from a Bacillus 
                     subtilis bacteriophage (Mol et al., 1995)"
                     /label=UGI
                     /translation="TNLSDIIEKETGKQLVIQESILMLPEEVEEVIGNKPESDILVHTA
                     YDESTDENVMLLTSDAPEYKPWALVIQDSNGENKIKML"
     protein_bind    complement(22146..22170)
                     /gene="mutant version of attB"
                     /label=attB2
                     /bound_moiety="BP Clonase(TM)"
                     /note="recombination site for the Gateway(R) BP reaction"
ORIGIN
        1 ggccctctag aggatccccg gcaccctact tagatcaaca cataaaagtt agtaagtgaa
       61 gaaccacaac aacaacacta gattcatctt caagtgtatg taggtatagt aacatgaaca
      121 agaacagact caagtacaag atcgcatacg aaaatggaaa tggcaatgtc acttccacat
      181 aatcaaacac gaatcctcat atcaacaagg cctgagattc taactagctc ataacaactt
      241 agccaatagt tacttgagac taccaaatgt atgtagaact aaagactaag ggacagagag
      301 ttcgtctaaa caggtgaatc tagtcgttgt tatctaataa acaattcagc cccaaatgca
      361 gaacacacat agagctctct attgattcaa attacgatct gatactgata acgtctagat
      421 ttttagggtt aaagcaatca atcacctgac gattcaaggt ggttggatca tgacgattcc
      481 agaaaacatc aagcaagctc tcaaagctac actctttggg atcatactga actctaacaa
      541 cctcgttatg tcccgtagtg ccagtacaga catcctcgta actcggattg tgcacgatgc
      601 catggctata cccaacctcg gtcttggtca caccaggaac tctctggtaa gctagctcca
      661 ctccccagaa acaaccggcg ccaaattgcg cgaattgctg acctgaagac ggaacatcat
      721 cgtcgggtcc ttgggcgatt gcggcggaag atgggtcagc ttgggcttga ggacgagacc
      781 cgaatccgag tctgttgaaa aggttgttca ttggggattt gtatacggag attggtcgtc
      841 gagaggtttg agggaaagga caaatgggtt tggctctgga gaaagagagt gcggctttag
      901 agagagaatt gagaggttta gagagagatg cggcggcgat gagcggagga gagacgacga
      961 ggacctgcat tatcaaagca gtgacgtggt gaaatttgga acttttaaga ggcagataga
     1021 tttattattt gtatccattt tcttcattgt tctagaatgt cgcggaacaa attttaaaac
     1081 taaatcctaa atttttctaa ttttgttgcc aatagtggat atgtgggccg tatagaagga
     1141 atctattgaa ggcccaaacc catactgacg agcccaaagg ttcgttttgc gttttatgtt
     1201 tcggttcgat gccaacgcca cattctgagc taggcaaaaa acaaacgtgt ctttgaatag
     1261 actcctctcg ttaacacatg cagcggctgc atggtgacgc cattaacacg tggcctacaa
     1321 ttgcatgatg tctccattga cacgtgactt ctcgtctcct ttcttaatat atctaacaaa
     1381 cactcctacc tcttccaaaa tatatacaca tctttttgat caatctctca ttcaaaatct
     1441 cattctctct agtaaacaag aacaaaaaaa tggcggatac agctagagga acccatcacg
     1501 atatcatcgg cagagaccag tacccgatga tgggccgaga ccgagaccag taccagatgt
     1561 ccggacgagg atctgactac tccaagtcta ggcagattgc taaagctgca actgctgtca
     1621 cagctggtgg ttccctcctt gttctctcca gccttaccct tgttggaact gtcatagctt
     1681 tgactgttgc aacacctctg ctcgttatct tcagcccaat ccttgtcccg gctctcatca
     1741 cagttgcact cctcatcacc ggttttcttt cctctggagg gtttggcatt gccgctataa
     1801 ccgttttctc ttggatttac aagtaagcac acatttatca tcttacttca taattttgtg
     1861 caatatgtgc atgcatgtgt tgagccagta gctttggatc aatttttttg gtcgaataac
     1921 aaatgtaaca ataagaaatt gcaaattcta gggaacattt ggttaactaa atacgaaatt
     1981 tgacctagct agcttgaatg tgtctgtgta tatcatctat ataggtaaaa tgcttggtat
     2041 gatacctatt gattgtgaat aggtacgcaa cgggagagca cccacaggga tcagacaagt
     2101 tggacagtgc aaggatgaag ttgggaagca aagctcagga tctgaaagac agagctcagt
     2161 actacggaca gcaacatact ggtggggaac atgaccgtga ccgtactcgt ggtggccagc
     2221 acactactca agggtgggcg cgccgaccca gctttcttgt acaaagtggt gatatcccgc
     2281 ggatggtgag caagggcgag gagctgttca ccggggtggt gcccatcctg gtcgagctgg
     2341 acggcgacgt aaacggccac aagttcagcg tgtccggcga gggcgagggc gatgccacct
     2401 acggcaagct gaccctgaag ttcatctgca ccaccggcaa gctgcccgtg ccctggccca
     2461 ccctcgtgac caccctgacc tacggcgtgc agtgcttcag ccgctacccc gaccacatga
     2521 agcagcacga cttcttcaag tccgccatgc ccgaaggcta cgtccaggag cgcaccatct
     2581 tcttcaagga cgacggcaac tacaagaccc gcgccgaggt gaagttcgag ggcgacaccc
     2641 tggtgaaccg catcgagctg aagggcatcg acttcaagga ggacggcaac atcctggggc
     2701 acaagctgga gtacaactac aacagccaca acgtctatat catggccgac aagcagaaga
     2761 acggcatcaa ggtgaacttc aagatccgcc acaacatcga ggacggcagc gtgcagctcg
     2821 ccgaccacta ccagcagaac acccccatcg gcgacggccc cgtgctgctg cccgacaacc
     2881 actacctgag cacccagtcc gccctgagca aagaccccaa cgagaagcgc gatcacatgg
     2941 tcctgctgga gttcgtgacc gccgccggga tcactctcgg catggacgag ctgtacgaac
     3001 ccggcatgtt acgtcctgta gaaaccccaa cccgtgaaat caaaaaactc gacggcctgt
     3061 gggcattcag tctggatcgc gaccgcaaac cgaagtcggc ggcttttctg ctgcaaaaac
     3121 gctggactgg catgaacttc ggtgaaaaac cgcagcaggg aggcaaacaa tgaccatggc
     3181 ggccgggagg gccatgctag agtccgcaaa aatcaccagt ctctctctac aaatctatct
     3241 ctctctattt ttctccagaa taatgtgtga gtagttccca gataagggaa ttagggttct
     3301 tatagggttt cgctcatgtg ttgagcatat aagaaaccct tagtatgtat ttgtatttgt
     3361 aaaatacttc tatcaataaa atttctaatt cctaaaacca aaatccagtg acctgcaggc
     3421 atgcgacctc gaattatcga tcatgagcgg agaattaagg gagtcacgtt atgacccccg
     3481 ccgatgacgc gggacaagcc gttttacgtt tggaactgac agaaccgcaa cgttgaagga
     3541 gccactgagc cgcgggtttc tggagtttaa tgagctaagc acatacgtca gaaaccatta
     3601 ttgcgcgttc aaaagtcgcc taaggtcact atcagctagc aaatatttct tgtcaaaaat
     3661 gctccactga cgttccataa attcccctcg gtatccaatt agagtctcat attcactctc
     3721 aactcgatcg aggcatgatt gaacaagatg gattgcacgc aggttctccg gccgcttggg
     3781 tggagaggct attcggctat gactgggcac aacagacaat cggctgctct gatgccgccg
     3841 tgttccggct gtcagcgcag gggcgcccgg ttctttttgt caagaccgac ctgtccggtg
     3901 ccctgaatga actccaagac gaggcagcgc ggctatcgtg gctggccacg acgggcgttc
     3961 cttgcgcagc tgtgctcgac gttgtcactg aagcgggaag ggactggctg ctattgggcg
     4021 aagtgccggg gcaggatctc ctgtcatctc accttgctcc tgccgagaaa gtatccatca
     4081 tggctgatgc aatgcggcgg ctgcatacgc ttgatccggc tacctgccca ttcgaccacc
     4141 aagcgaaaca tcgcatcgag cgagcacgta ctcggatgga agccggtctt gtcgatcagg
     4201 atgatctgga cgaagagcat caggggctcg cgccagccga actgttcgcc aggctcaagg
     4261 cgcggatgcc cgacggcgag gatctcgtcg tgacccacgg cgatgcctgc ttgccgaata
     4321 tcatggtgga aaatggccgc ttttctggat tcatcgactg tggccggctg ggtgtggcgg
     4381 accgctatca ggacatagcg ttggctaccc gtgatattgc tgaagagctt ggcggcgaat
     4441 gggctgaccg cttcctcgtg ctttacggta tcgccgctcc cgattcgcag cgcatcgcct
     4501 tctatcgcct tcttgacgag ttcttctgag cgggactctg gggttcggac tctagctaga
     4561 gtcaagcaga tcgttcaaac atttggcaat aaagtttctt aagattgaat cctgttgccg
     4621 gtcttgcgat gattatcata taatttctgt tgaattacgt taagcatgta ataattaaca
     4681 tgtaatgcat gacgttattt atgagatggg tttttatgat tagagtcccg caattataca
     4741 tttaatacgc gatagaaaac aaaatatagc gcgcaaacta ggataaatta tcgcgcgcgg
     4801 tgtcatctat gttactagat cgaccggcat gcaagctgat aattcaattc ggcgttaatt
     4861 cagtacatta aaaacgtccg caatgtgtta ttaagttgtc taagcgtcaa tttgtttaca
     4921 ccacaatata tcctgccacc agccagccaa cagctccccg accggcagct cggcacaaaa
     4981 tcaccactcg atacaggcag cccatcagtc cgggacggcg tcagcgggag agccgttgta
     5041 aggcggcaga ctttgctcat gttaccgatg ctattcggaa gaacggcaac taagctgccg
     5101 ggtttgaaac acggatgatc tcgcggaggg tagcatgttg attgtaacga tgacagagcg
     5161 ttgctgcctg tgatcaattc gggcacgaac ccagtggaca taagcctgtt cggttcgtaa
     5221 gctgtaatgc aagtagcgta tgcgctcacg caactggtcc agaaccttga ccgaacgcag
     5281 cggtggtaac ggcgcagtgg cggttttcat ggcttgttat gactgttttt ttggggtaca
     5341 gtctatgcct cgggcatcca agcagcaagc gcgttacgcc gtgggtcgat gtttgatgtt
     5401 atggagcagc aacgatgtta cgcagcaggg cagtcgccct aaaacaaagt taaacatcat
     5461 gggggaagcg gtgatcgccg aagtatcgac tcaactatca gaggtagttg gcgtcatcga
     5521 gcgccatctc gaaccgacgt tgctggccgt acatttgtac ggctccgcag tggatggcgg
     5581 cctgaagcca cacagtgata ttgatttgct ggttacggtg accgtaaggc ttgatgaaac
     5641 aacgcggcga gctttgatca acgacctttt ggaaacttcg gcttcccctg gagagagcga
     5701 gattctccgc gctgtagaag tcaccattgt tgtgcacgac gacatcattc cgtggcgtta
     5761 tccagctaag cgcgaactgc aatttggaga atggcagcgc aatgacattc ttgcaggtat
     5821 cttcgagcca gccacgatcg acattgatct ggctatcttg ctgacaaaag caagagaaca
     5881 tagcgttgcc ttggtaggtc cagcggcgga ggaactcttt gatccggttc ctgaacagga
     5941 tctatttgag gcgctaaatg aaaccttaac gctatggaac tcgccgcccg actgggctgg
     6001 cgatgagcga aatgtagtgc ttacgttgtc ccgcatttgg tacagcgcag taaccggcaa
     6061 aatcgcgccg aaggatgtcg ctgccgactg ggcaatggag cgcctgccgg cccagtatca
     6121 gcccgtcata cttgaagcta gacaggctta tcttggacaa gaagaagatc gcttggcctc
     6181 gcgcgcagat cagttggaag aatttgtcca ctacgtgaaa ggcgagatca ccaaggtagt
     6241 cggcaaataa tgtctagcta gaaattcgtt caagccgacg ccgcttcgcg gcgcggctta
     6301 actcaagcgt tagatgcact aagcacataa ttgctcacag ccaaactatc aggtcaagtc
     6361 tgcttttatt atttttaagc gtgcataata agccctacac aaattgggag atatatcatg
     6421 catgaccaaa atcccttaac gtgagttwnn nntcgttcca ctgagcgtca gaccccgtag
     6481 aaaagatcaa aggatcttct tgagatcctt tttttctgcg cgtaatctgc tgcttgcaaa
     6541 caaaaaaacc accgctacca gcggtggttt gtttgccgga tcaagagcta ccaactcttt
     6601 ttccgaaggt aactggcttc agcagagcgc agataccaaa tactgttctt ctagtgtagc
     6661 cgtagttagg ccaccacttc aagaactctg tagcaccgcc tacatacctc gctctgctaa
     6721 tcctgttacc agtggctgct gccagtggcg ataagtcgtg tcttaccggg ttggactcaa
     6781 gacgatagtt accggataag gcgcagcggt cgggctgaac ggggggttcg tgcacacagc
     6841 ccagcttgga gcgaacgacc tacaccgaac tgagatacct acagcgtgag ctatgagaaa
     6901 gcgccacgct tcccgaaggg agaaaggcgg acaggtatcc ggtaagcggc agggtcggaa
     6961 caggagagcg cacgagggag cttccagggg gaaacgcctg gtatctttat agtcctgtcg
     7021 ggtttcgcca cctctgactt gagcgtcgat ttttgtgatg ctcgtcaggg gggcggagcc
     7081 tatggaaaaa cgccagcaac gcggcctttt tacggttcct ggccttttgc tggccttttg
     7141 ctcacatgtt ctttcctgcg ttatcccctg attctgtgga taaccgtatt accgcctttg
     7201 agtgagctga taccgctcgc cgcagccgaa cgaccgagcg cagcgagtca gtgagcgagg
     7261 aagcggaaga gcgcctgatg cggtattttc tccttacgca tctgtgcggt atttcacacc
     7321 gcatatggtg cactctcagt acaatctgct ctgatgccgc atagttaagc cagtatacac
     7381 tccgctatcg ctacgtgact gggtcatggc tgcgccccga cacccgccaa cacccgctga
     7441 cgcgccctga cgggcttgtc tgctcccggc atccgcttac agacaagctg tgaccgtctc
     7501 cgggagctgc atgtgtcaga ggttttcacc gtcatcaccg aaacgcgcga ggcagggtgc
     7561 cttgatgtgg gcgccggcgg tcgagtggcg acggcgcggc ttgtccgcgc cctggtagat
     7621 tgcctggccg taggccagcc atttttgagc ggccagcggc cgcgataggc cgacgcgaag
     7681 cggcggggcg tagggagcgc agcgaccgaa gggtaggcgc tttttgcagc tcttcggctg
     7741 tgcgctggcc agacagttat gcacaggcca ggcgggtttt aagagtttta ataagtttta
     7801 aagagtttta ggcggaaaaa tcgccttttt tctcttttat atcagtcact tacatgtgtg
     7861 accggttccc aatgtacggc tttgggttcc caatgtacgg gttccggttc ccaatgtacg
     7921 gctttgggtt cccaatgtac gtgctatcca caggaaagag accttttcga cctttttccc
     7981 ctgctagggc aatttgccct agcatctgct ccgtacatta ggaaccggcg gatgcttcgc
     8041 cctcgatcag gttgcggtag cgcatgacta ggatcgggcc agcctgcccc gcctcctcct
     8101 tcaaatcgta ctccggcagg tcatttgacc cgatcagctt gcgcacggtg aaacagaact
     8161 tcttgaactc tccggcgctg ccactgcgtt cgtagatcgt cttgaacaac catctggctt
     8221 ctgccttgcc tgcggcgcgg cgtgccaggc ggtagagaaa acggccgatg ccgggatcga
     8281 tcaaaaagta atcggggtga accgtcagca cgtccgggtt cttgccttct gtgatctcgc
     8341 ggtacatcca atcagctagc tcgatctcga tgtactccgg ccgcccggtt tcgctcttta
     8401 cgatcttgta gcggctaatc aaggcttcac cctcggatac cgtcaccagg cggccgttct
     8461 tggccttctt cgtacgctgc atggcaacgt gcgtggtgtt taaccgaatg caggtttcta
     8521 ccaggtcgtc tttctgcttt ccgccatcgg ctcgccggca gaacttgagt acgtccgcaa
     8581 cgtgtggacg gaacacgcgg ccgggcttgt ctcccttccc ttcccggtat cggttcatgg
     8641 attcggttag atgggaaacc gccatcagta ccaggtcgta atcccacaca ctggccatgc
     8701 cggccggccc tgcggaaacc tctacgtgcc cgtctggaag ctcgtagcgg atcacctcgc
     8761 cagctcgtcg gtcacgcttc gacagacgga aaacggccac gtccatgatg ctgcgactat
     8821 cgcgggtgcc cacgtcatag agcatcggaa cgaaaaaatc tggttgctcg tcgcccttgg
     8881 gcggcttcct aatcgacggc gcaccggctg ccggcggttg ccgggattct ttgcggattc
     8941 gatcagcggc cgcttgccac gattcaccgg ggcgtgcttc tgcctcgatg cgttgccgct
     9001 gggcggcctg cgcggccttc aacttctcca ccaggtcatc acccagcgcc gcgccgattt
     9061 gtaccgggcc ggatggtttg cgaccgctca cgccgattcc tcgggcttgg gggttccagt
     9121 gccattgcag ggccggcaga caacccagcc gcttacgcct ggccaaccgc ccgttcctcc
     9181 acacatgggg cattccacgg cgtcggtgcc tggttgttct tgattttcca tgccgcctcc
     9241 tttagccgct aaaattcatc tactcattta ttcatttgct catttactct ggtagctgcg
     9301 cgatgtattc agatagcagc tcggtaatgg tcttgccttg gcgtaccgcg tacatcttca
     9361 gcttggtgtg atcctccgcc ggcaactgaa agttgacccg cttcatggct ggcgtgtctg
     9421 ccaggctggc caacgttgca gccttgctgc tgcgtgcgct cggacggccg gcacttagcg
     9481 tgtttgtgct tttgctcatt ttctctttac ctcattaact caaatgagtt ttgatttaat
     9541 ttcagcggcc agcgcctgga cctcgcgggc agcgtcgccc tcgggttctg attcaagaac
     9601 ggttgtgccg gcggcggcag tgcctgggta gctcacgcgc tgcgtgatac gggactcaag
     9661 aatgggcagc tcgtacccgg ccagcgcctc ggcaacctca ccgccgatgc gcgtgccttt
     9721 gatcgcccgc gacacgacaa aggccgcttg tagccttcca tccgtgacct caatgcgctg
     9781 cttaaccagc tccaccaggt cggcggtggc ccatatgtcg taagggcttg gctgcaccgg
     9841 aatcagcacg aagtcggctg ccttgatcgc ggacacagcc aagtccgccg cctggggcgc
     9901 tccgtcgatc actacgaagt cgcgccggcc gatggccttc acgtcgcggt caatcgtcgg
     9961 gcggtcgatg ccgacaacgg ttagcggttg atcttcccgc acggccgccc aatcgcgggc
    10021 actgccctgg ggatcggaat cgactaacag aacatcggcc ccggcgagtt gcagggcgcg
    10081 ggctagatgg gttgcgatgg tcgtcttgcc tgacccgcct ttctggttaa gtacagcgat
    10141 aaccttcatg cgttcccctt gcgtatttgt ttatttactc atcgcatcat atacgcagcg
    10201 accgcatgac gcaagctgtt ttactcaaat acacatcacc tttttagacg gcggcgctcg
    10261 gtttcttcag cggccaagct ggccggccag gccgccagct tggcatcaga caaaccggcc
    10321 aggatttcat gcagccgcac ggttgagacg tgcgcgggcg gctcgaacac gtacccggcc
    10381 gcgatcatct ccgcctcgat ctcttcggta atgaaaaacg gttcgtcctg gccgtcctgg
    10441 tgcggtttca tgcttgttcc tcttggcgtt cattctcggc ggccgccagg gcgtcggcct
    10501 cggtcaatgc gtcctcacgg aaggcaccgc gccgcctggc ctcggtgggc gtcacttcct
    10561 cgctgcgctc aagtgcgcgg tacagggtcg agcgatgcac gccaagcagt gcagccgcct
    10621 ctttcacggt gcggccttcc tggtcgatca gctcgcgggc gtgcgcgatc tgtgccgggg
    10681 tgagggtagg gcgggggcca aacttcacgc ctcgggcctt ggcggcctcg cgcccgctcc
    10741 gggtgcggtc gatgattagg gaacgctcga actcggcaat gccggcgaac acggtcaaca
    10801 ccatgcggcc ggccggcgtg gtggtgtcgg cccacggctc tgccaggcta cgcaggcccg
    10861 cgccggcctc ctggatgcgc tcggcaatgt ccagtaggtc gcgggtgctg cgggccaggc
    10921 ggtctagcct ggtcactgtc acaacgtcgc cagggcgtag gtggtcaagc atcctggcca
    10981 gctccgggcg gtcgcgcctg gtgccggtga tcttctcgga aaacagcttg gtgcagccgg
    11041 ccgcgtgcag ttcggcccgt tggttggtca agtcctggtc gtcggtgctg acgcgggcat
    11101 agcccagcag gccagcggcg gcgctcttgt tcatggcgta atgtctccgg ttctagtcgc
    11161 aagtattcta ctttatgcga ctaaaacacg cgacaagaaa acgccaggaa aagggcaggg
    11221 cggcagcctg tcgcgtaact taggacttgt gcgacatgtc gttttcagaa gacggctgca
    11281 ctgaacgtca gaagccgact gcactatagc agcggagggg ttggatcaaa gtactttaaa
    11341 gtactttaaa gtactttaaa gtactttgat cccgagggga accctgtggt tggcatgcac
    11401 atacaaatgg acgaacggat aaaccttttc acgccctttt aaatatccga ttattctaat
    11461 aaacgctctt ttctcttagg tttacccgcc aatatatcct gtcaaacact gatagtttaa
    11521 actgaaggcg ggaaacgaca atctgatcca agctcaagct aagctctcaa cttttgattc
    11581 gctatttgca gtgcacctgt ggcgttcatc acatcttttg tgacactgtt tgcactggtc
    11641 attgctatta caaaggacct tcctgatgtt gaaggagatc gaaagtaagt aactgcacgc
    11701 ataaccattt tctttccgct ctttggctca atccatttga cagtcaaaga caatgtttaa
    11761 ccagctccgt ttgatatatt gtctttatgt gtttgttcaa gcatgtttag ttaatcatgc
    11821 ctttgattga tcttgaatag gttccaaata tcaaccctgg caacaaaact tggagtgaga
    11881 aacattgcat tcctcggttc tggacttctg ctagtaaatt atgtttcagc catatcacta
    11941 gctttctaca tgcctcaggt gaattcatct atttccgtct taactatttc ggttaattaa
    12001 agcacgaaca ccattactgc atgtagaagc ttgataaact atcgccacca atttattttt
    12061 gttgcgatat tgttactttc ctcagtatgc agctttgaaa agaccaaccc tcttatcctt
    12121 taacaatgaa caggttttta gaggtagctt gatgattcct gcacatgtga tcttggcttc
    12181 aggcttaatt ttccaggtaa agcattatga gatactctta tatctcttac atacttttga
    12241 gataatgcac aagaacttca taactatatg ctttagtttc tgcatttgac actgccaaat
    12301 tcattaatct ctaatatctt tgttgttgat ctttggtaga catgggtact agaaaaagca
    12361 aactacacca aggtaaaata cttttgtaca aacataaact cgttatcacg gaacatcaat
    12421 ggagtgtata tctaacggag tgtagaaaca tttgattatt gcaggaagct atctcaggat
    12481 attatcggtt tatatggaat ctcttctacg cagagtatct gttattcccc ttcctctagc
    12541 tttcaatttc atggtgagga tatgcagttt tctttgtata tcattcttct tcttctttgt
    12601 agcttggagt caaaatcggt tccttcatgt acatacatca aggatatgtc cttctgaatt
    12661 tttatatctt gcaataaaaa tgcttgtacc aattgaaaca ccagcttttt gagttctatg
    12721 atcactgact tggttctaac caaaaaaaaa aaaatgttta atttacatat ctaaaagtag
    12781 gtttagggaa acctaaacag taaaatattt gtatattatt cgaatttcac tcatcataaa
    12841 aacttaaatt gcaccataaa attttgtttt actattaatg atgtaatttg tgtaacttaa
    12901 gataaaaata atattccgta agttaaccgg ctaaaaccac gtataaacca gggaacctgt
    12961 taaaccggtt ctttactgga taaagaaatg aaagcccatg tagacagctc cattagagcc
    13021 caaaccctaa atttctcatc tatataaaag gagtgacatt agggtttttg ttcgtcctct
    13081 taaagcttct cgttttctct gccgtctctc tcattcgcgc gacgcaaacg atcttcaggt
    13141 gatcttcttt ctccaaatcc tctctcataa ctctgatttc gtacttgtgt atttgagctc
    13201 acgctctgtt tctctcacca cagccatgtt taaacaagct tctcgtctcc tctcccgatc
    13261 tgtcgccgcc gcatcttcca aatcggtgac gactcgtgcc ttttcaacgg aacttccatc
    13321 gacgctcgat tccgctagtg atatcacaag tttgtacaaa aaagcaggct tttacccata
    13381 cgatgttcca gattacgctg atatcgccga tctacgcacg ctcggctaca gccagcagca
    13441 acaggagaag atcaaaccga aggttcgttc gacagtggcg cagcaccacg aggcactggt
    13501 cggccacggg tttacacacg cgcacatcgt tgcgttaagc caacacccgg cagcgttagg
    13561 gaccgtcgct gtcaagtatc aggacatgat cgcagcgttg ccagaggcga cacacgaagc
    13621 gatcgttggc gtcggcaaac agtggtccgg cgcacgcgct ctggaggcct tgctcacggt
    13681 ggcgggagag ttgagaggtc caccgttaca gttggacaca ggccaacttc tcaagattgc
    13741 aaaacgtggc ggcgtgaccg cagtggaggc agtgcatgca tggcgcaatg cactgacggg
    13801 tgccccgctc aacctgaccc cagaccaagt tgtcgcgatt gcaagcaaca acggaggcaa
    13861 acaagcctta gaaacagtcc agagattgtt gccggtgctg tgccaagacc acggcctgac
    13921 cccagaacag gttgtggcca tcgccagcaa cataggtggc aagcaggccc tcgaaaccgt
    13981 ccagagactg ttaccggttc tctgccaggc ccacggcctg accccagacc aggttgtggc
    14041 catcgccagc aacataggtg gcaagcaggc cctcgaaacc gtccagagac tgttaccggt
    14101 tctctgccag gcccacggcc tgaccccagc ccaggttgtg gccatcgcca gcaacatagg
    14161 tggcaagcag gccctcgaaa ccgtccagag actgttaccg gttctctgcc aggaccacgg
    14221 cctgacccca gaccaagttg tcgcgattgc aagcaacaac ggaggcaaac aagccttaga
    14281 aacagtccag agattgttgc cggtgctgtg ccaagaccac ggcctgaccc cggaacaggt
    14341 ggttgcaatc gcgtcacacg atgggggaaa gcaggcccta gaaaccgttc agcgactcct
    14401 gcccgtcctg tgccaggccc acggcctgac ccccgaccag gttgtcgcta ttgctagtaa
    14461 cggcggaggc aaacaggcgc tggaaacagt tcagcgcctc ttgccggtct tgtgtcaggc
    14521 ccacggcctg accccagccc aggttgtggc catcgccagc aacataggtg gcaagcaggc
    14581 cctcgaaacc gtccagagac tgttaccggt tctctgccag gaccacggcc tgacccccga
    14641 ccaggttgtc gctattgcta gtaacggcgg aggcaaacag gcgctggaaa cagttcagcg
    14701 cctcttgccg gtcttgtgtc aggaccacgg cctgacccca gaacaagttg tcgcgattgc
    14761 aagcaacaac ggaggcaaac aagccttaga aacagtccag agattgttgc cggtgctgtg
    14821 ccaagcccac ggcctgaccc cagaccaggt tgtggccatc gccagcaaca taggtggcaa
    14881 gcaggccctc gaaaccgtcc agagactgtt accggttctc tgccaggccc acggcctgac
    14941 cccagcccag gttgtggcca tcgccagcaa cataggtggc aagcaggccc tcgaaaccgt
    15001 ccagagactg ttaccggttc tctgccagga ccacggcctg accccagacc aggttgtggc
    15061 catcgccagc aacataggtg gcaagcaggc cctcgaaacc gtccagagac tgttaccggt
    15121 tctctgccag gaccacggcc tgaccccgga acaggtggtt gcaatcgcgt cacacgatgg
    15181 gggaaagcag gccctagaaa ccgttcagcg actcctgccc gtcctgtgcc aggcccacgg
    15241 cctgacccca gaccaggttg tggccatcgc cagcaacata ggtggcaagc aggccctcga
    15301 aaccgtccag agactgttac cggttctctg ccaggcccac ggcctgaccc cagcccaggt
    15361 tgtggccatc gccagcaaca taggtggcaa gcaggccctc gaaaccgtcc agagactgtt
    15421 accggttctc tgccaggacc acggcctgac cccagaccaa gttgtcgcga ttgcaagcaa
    15481 caacggaggc aaacaagcct tagaaacagt ccagagattg ttgccggtgc tgtgccaaga
    15541 ccacggcctg acccccgaac aggttgtcgc tattgctagt aacggcggag gcaaacaggc
    15601 gctggaaaca gttcagcgcc tcttgccggt cttgtgtcag gcccacggcc tgaccccaga
    15661 ccaggttgtg gccatcgcca gcaacatagg tggcaagcag gccctcgaaa ccgtccagag
    15721 actgttaccg gttctctgcc aggcccacgg cctgacccct gagcaggtag tggctattgc
    15781 atccaacgga gggggcagac ccgcactgga gtcaattgtt gcccagttat ctcgccctga
    15841 tccggcgttg gccgcgttga ccaacgacca cctcgtcgcc ttggcctgcc tcggcgggcg
    15901 tcctgcgctg gatgcagtga aaaagggatt ggggggatct ggtagctatg cgttaggacc
    15961 ctatcagatt tcagctcctc aattgcctgc ctataatggg caaactgttg gcacctttta
    16021 ctacgtcaat gatgctggag ggttagaatc caaggtgttc tcaagtggtg gttctggagg
    16081 tagtacgaat ctttcggaca tcatagagaa ggaaactgga aaacagctcg ttatccaaga
    16141 gagcattctc atgttgccag aagaagttga agaggttata ggcaacaaac cggaatctga
    16201 cattctggta cataccgctt atgatgagtc aacagatgag aacgtcatgc ttttgacatc
    16261 tgatgcacca gaatacaaac cttgggcact tgtgattcag gattccaatg gtgagaacaa
    16321 gatcaagatg ctatgataac tcgagcgatc ctctagacac ccaacttttc tatacaaagt
    16381 tgtgaatatg aagatgaaga tgaaatattt ggtgtgtcaa ataaaaagct tgtgtgctta
    16441 agtttgtgtt tttttcttgg cttgttgtgt tatgaatttg tggctttttc taatattaaa
    16501 tgaatgtaag atctcattat aatgaataaa caaatgtttc tataatccat tgtgaatgtt
    16561 ttgttggatc tcttctgcag catataacta ctgtatgtgc tatggtatgg actatggaat
    16621 atgattaaag ataagatggg ctcatagagt aaaacgaggc gagggaccta taaacctccc
    16681 ttcatcatgc tatttcatga tctattttat aaaataaaga tgtagaaaaa agtaagcgta
    16741 ataaccgcaa aacaaatgat ttaaaacatg gcacataatg aggagattaa gttcggttta
    16801 cgtttatttt agtactaatt gtaacgtgag actacgtatc gggaatcgcc taattaaagc
    16861 attaatgcga acctgattag attcaccgac cctcctatcg tgtcgacctt tctgtttctt
    16921 agaatttttt ggtagtctat gtactaataa tgtcagcttc gtatttattt cataagcaat
    16981 ttgcatttgc aatttgtttt ttacttttat ttttattgta ttgtggaatg tggactcgta
    17041 ccaacatgaa gttatatacc accaaaaaaa ttacagttag tcaaaagatt cacgagtgag
    17101 agctacttat gattgtcttt tacgtatatg tctaattgtc tatttgctca ataatctttg
    17161 tactttcttt tgtcgttgat aaatctagag gatccccctc aacttttgat tcgctatttg
    17221 cagtgcacct gtggcgttca tcacatcttt tgtgacactg tttgcactgg tcattgctat
    17281 tacaaaggac cttcctgatg ttgaaggaga tcgaaagtaa gtaactgcac gcataaccat
    17341 tttctttccg ctctttggct caatccattt gacagtcaaa gacaatgttt aaccagctcc
    17401 gtttgatata ttgtctttat gtgtttgttc aagcatgttt agttaatcat gcctttgatt
    17461 gatcttgaat aggttccaaa tatcaaccct ggcaacaaaa cttggagtga gaaacattgc
    17521 attcctcggt tctggacttc tgctagtaaa ttatgtttca gccatatcac tagctttcta
    17581 catgcctcag gtgaattcat ctatttccgt cttaactatt tcggttaatt aaagcacgaa
    17641 caccattact gcatgtagaa gcttgataaa ctatcgccac caatttattt ttgttgcgat
    17701 attgttactt tcctcagtat gcagctttga aaagaccaac cctcttatcc tttaacaatg
    17761 aacaggtttt tagaggtagc ttgatgattc ctgcacatgt gatcttggct tcaggcttaa
    17821 ttttccaggt aaagcattat gagatactct tatatctctt acatactttt gagataatgc
    17881 acaagaactt cataactata tgctttagtt tctgcatttg acactgccaa attcattaat
    17941 ctctaatatc tttgttgttg atctttggta gacatgggta ctagaaaaag caaactacac
    18001 caaggtaaaa tacttttgta caaacataaa ctcgttatca cggaacatca atggagtgta
    18061 tatctaacgg agtgtagaaa catttgatta ttgcaggaag ctatctcagg atattatcgg
    18121 tttatatgga atctcttcta cgcagagtat ctgttattcc ccttcctcta gctttcaatt
    18181 tcatggtgag gatatgcagt tttctttgta tatcattctt cttcttcttt gtagcttgga
    18241 gtcaaaatcg gttccttcat gtacatacat caaggatatg tccttctgaa tttttatatc
    18301 ttgcaataaa aatgcttgta ccaattgaaa caccagcttt ttgagttcta tgatcactga
    18361 cttggttcta accaaaaaaa aaaaaatgtt taatttacat atctaaaagt aggtttaggg
    18421 aaacctaaac agtaaaatat ttgtatatta ttcgaatttc actcatcata aaaacttaaa
    18481 ttgcaccata aaattttgtt ttactattaa tgatgtaatt tgtgtaactt aagataaaaa
    18541 taatattccg taagttaacc ggctaaaacc acgtataaac cagggaacct gttaaaccgg
    18601 ttctttactg gataaagaaa tgaaagccca tgtagacagc tccattagag cccaaaccct
    18661 aaatttctca tctatataaa aggagtgaca ttagggtttt tgttcgtcct cttaaagctt
    18721 ctcgttttct ctgccgtctc tctcattcgc gcgacgcaaa cgatcttcag gtgatcttct
    18781 ttctccaaat cctctctcat aactctgatt tcgtacttgt gtatttgagc tcacgctctg
    18841 tttctctcac cacagccatg tttaaacaag cttctcgtct cctctcccga tctgtcgccg
    18901 ccgcatcttc caaatcggtg acgactcgtg ccttttcaac ggaacttcca tcgacgctcg
    18961 attccacaac tttgtataat aaagttgata aggagaccgc cgctgccaag ttcgagagac
    19021 agcacatgga cagcatcgat atcgccgatc tacgcacgct cggctacagc cagcagcaac
    19081 aggagaagat caaaccgaag gttcgttcga cagtggcgca gcaccacgag gcactggtcg
    19141 gccacgggtt tacacacgcg cacatcgttg cgttaagcca acacccggca gcgttaggga
    19201 ccgtcgctgt caagtatcag gacatgatcg cagcgttgcc agaggcgaca cacgaagcga
    19261 tcgttggcgt cggcaaacag tggtccggcg cacgcgctct ggaggccttg ctcacggtgg
    19321 cgggagagtt gagaggtcca ccgttacagt tggacacagg ccaacttctc aagattgcaa
    19381 aacgtggcgg cgtgaccgca gtggaggcag tgcatgcatg gcgcaatgca ctgacgggtg
    19441 ccccgctcaa cctgaccccg gaccaggtgg ttgcaatcgc gtcacacgat gggggaaagc
    19501 aggccctaga aaccgttcag cgactcctgc ccgtcctgtg ccaggaccac ggcctgaccc
    19561 cagaacaagt tgtcgcgatt gcaagcaaca acggaggcaa acaagcctta gaaacagtcc
    19621 agagattgtt gccggtgctg tgccaagccc acggcctgac cccggaccag gtggttgcaa
    19681 tcgcgtcaca cgatggggga aagcaggccc tagaaaccgt tcagcgactc ctgcccgtcc
    19741 tgtgccaggc ccacggcctg accccagccc aagttgtcgc gattgcaagc aacaacggag
    19801 gcaaacaagc cttagaaaca gtccagagat tgttgccggt gctgtgccaa gaccacggcc
    19861 tgaccccaga ccaggttgtg gccatcgcca gcaacatagg tggcaagcag gccctcgaaa
    19921 ccgtccagag actgttaccg gttctctgcc aggaccacgg cctgaccccc gaacaggttg
    19981 tcgctattgc tagtaacggc ggaggcaaac aggcgctgga aacagttcag cgcctcttgc
    20041 cggtcttgtg tcaggcccac ggcctgaccc cagaccaggt tgtggccatc gccagcaaca
    20101 taggtggcaa gcaggccctc gaaaccgtcc agagactgtt accggttctc tgccaggccc
    20161 acggcctgac ccccgcccag gttgtcgcta ttgctagtaa cggcggaggc aaacaggcgc
    20221 tggaaacagt tcagcgcctc ttgccggtct tgtgtcagga ccacggcctg acccccgacc
    20281 aggttgtcgc tattgctagt aacggcggag gcaaacaggc gctggaaaca gttcagcgcc
    20341 tcttgccggt cttgtgtcag gaccacggcc tgaccccaga acaagttgtc gcgattgcaa
    20401 gcaacaacgg aggcaaacaa gccttagaaa cagtccagag attgttgccg gtgctgtgcc
    20461 aagcccacgg cctgaccccc gaccaggttg tcgctattgc tagtaacggc ggaggcaaac
    20521 aggcgctgga aacagttcag cgcctcttgc cggtcttgtg tcaggcccac ggcctgaccc
    20581 cagcccaagt tgtcgcgatt gcaagcaaca acggaggcaa acaagcctta gaaacagtcc
    20641 agagattgtt gccggtgctg tgccaagacc acggcctgac cccggaccag gtggttgcaa
    20701 tcgcgtcaca cgatggggga aagcaggccc tagaaaccgt tcagcgactc ctgcccgtcc
    20761 tgtgccagga ccacggcctg accccggaac aggtggttgc aatcgcgtca cacgatgggg
    20821 gaaagcaggc cctagaaacc gttcagcgac tcctgcccgt cctgtgccag gcccacggcc
    20881 tgaccccaga ccaggttgtg gccatcgcca gcaacatagg tggcaagcag gccctcgaaa
    20941 ccgtccagag actgttaccg gttctctgcc aggcccacgg cctgacccca gcccaggttg
    21001 tggccatcgc cagcaacata ggtggcaagc aggccctcga aaccgtccag agactgttac
    21061 cggttctctg ccaggaccac ggcctgaccc ccgaccaggt tgtcgctatt gctagtaacg
    21121 gcggaggcaa acaggcgctg gaaacagttc agcgcctctt gccggtcttg tgtcaggacc
    21181 acggcctgac ccccgaacag gttgtcgcta ttgctagtaa cggcggaggc aaacaggcgc
    21241 tggaaacagt tcagcgcctc ttgccggtct tgtgtcaggc ccacggcctg accccggacc
    21301 aggtggttgc aatcgcgtca cacgatgggg gaaagcaggc cctagaaacc gttcagcgac
    21361 tcctgcccgt cctgtgccag gcccacggcc tgacccctga gcaggtagtg gctattgcat
    21421 cccacgacgg gggcagaccc gcactggagt caattgttgc ccagttatct cgccctgatc
    21481 cggcgttggc cgcgttgacc aacgaccacc tcgtcgcctt ggcctgcctc ggcgggcgtc
    21541 ctgcgctgga tgcagtgaaa aagggattgg ggggtagtcc aactccgtat ccgaattacg
    21601 ccaatgcagg acatgttgaa ggtcaatctg cattgttcat gagggataac ggcatttctg
    21661 aagggttggt gttccacaac aaccctgaag gaacatgtgg attttgcgtc aacatgacag
    21721 aaacccttct cccagaaaac gctaagatga cagtagttcc acctgaaggt gctattcctg
    21781 tcaaaagagg tgctactggt gaaaccaagg tgtttactgg gaattccaat tcacccaaaa
    21841 gcccaacgaa aggtgggtgt agtggaggat ctacaaatct ctctgacatc attgagaaag
    21901 agactggaaa gcaactagtc attcaggagt caatcctgat gttaccagag gaggttgagg
    21961 aagtgatagg caataagccc gaaagcgata tacttgttca tactgcctat gacgaatcga
    22021 cggatgagaa cgtaatgctt ctaacctcag atgctcctga gtacaaacct tgggcgttag
    22081 ttatccagga ttccaatgga gagaacaaga tcaagatgtt gtgataactc gagcgatcct
    22141 ctagaaccca gctttcttgt acaaagtggt gatatcccgc ggccatgcta gagtccgcaa
    22201 aaatcaccag tctctctcta caaatctatc tctctctatt tttctccaga ataatgtgtg
    22261 agtagttccc agataaggga attagggttc ttatagggtt tcgctcatgt gttgagcata
    22321 taagaaaccc ttagtatgta tttgtatttg taaaatactt ctatcaataa aatttctaat
    22381 tcctaaaacc aaaatccagt gacctgcagg catgcgacgt cg
//
