LOCUS       sequence-38887-e         671 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 671)
  AUTHORS   Zhu J, Smith K, Hsieh PN, Mburu YK, Chattopadhyay S, Sen GC, Sarkar 
            SN
  TITLE     High-throughput screening for TLR3-IFN regulatory factor 3 signaling
            pathway modulators identifies several antipsychotic drugs as TLR 
            inhibitors.
  JOURNAL   J Immunol. 2010 May 15;184(10):5768-76. Epub 2010 Apr 9.
  PUBMED    20382888
REFERENCE   2  (bases 1 to 671)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "J 
            Immunol."; date: "2010-05-15"; volume: "184(10)"; pages: "5768-76. 
            Epub 2010 Apr 9"
COMMENT     Sequence Label: hTLR3-pcDNA3
FEATURES             Location/Qualifiers
     source          1..671
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     primer_bind     52..71
                     /label=T7
                     /note="T7 promoter, forward primer"
     promoter        52..70
                     /label=T7 promoter
                     /note="promoter for bacteriophage T7 RNA polymerase"
     CDS             136..180
                     /codon_start=1
                     /product="leader sequence from mouse preprotrypsin"
                     /label=preprotrypsin leader
                     /translation="MSALLILALVGAAVA"
     CDS             181..204
                     /codon_start=1
                     /product="FLAG(R) epitope tag, followed by an enterokinase 
                     cleavage site"
                     /label=FLAG
                     /translation="DYKDDDDK"
ORIGIN
        1 agcgactctc tggctaacta gagaacccac tgcttactgg cttatcgaaa ttaatacgac
       61 tcactatagg gagacccaag cttggtaccg agctcggatc cactagtaac ggccgccagt
      121 gtgctggaat tcaccatgtc tgcacttctg atcctagctc ttgttggagc tgcagttgct
      181 gactacaaag acgatgacga caagcttggg atgctgtgtg catcctccac caccaagtgc
      241 actgttagcc atgaagttgc tgactgcagc cacctgaagt tgactcaggt acccgatgat
      301 ctacccacaa acataacagt gttgaacctt acccataatc aactcagaag attaccagcc
      361 gccaacttca caaggtatag ccagctaact agcttggatg taggatttaa caccatctca
      421 aaactggagc cagaattgtg ccagaaactt cccatgttaa aagttttgaa cctccagcac
      481 aatgagctat ctcaactttc tgataaaacc tttgccttct gcacgaattt gactggactc
      541 catctcatgt ccaactcaat ccagaaaatt aaaaataatc cctttgtcaa gcagaagaat
      601 ttaatcacat tagatctgtc tcataatggc ttgtcatcta caaaattagg aactcaggtt
      661 cagctggaaa t
//
