LOCUS       sequence-402704-        1593 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  in vitro transcription of RNA encoding human ACVR1 with mutations 
            T189V, S190A, and R206H.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1593)
  AUTHORS   Allen RS, Jones WD, Hale M, Warder BN, Shore EM, Mullins MC
  TITLE     Reduced GS domain serine/threonine requirements of Fibrodysplasia 
            Ossificans Progressiva mutant type I BMP receptor ACVR1 in the 
            zebrafish.
  JOURNAL   J Bone Miner Res. 2023 Jun 17. doi: 10.1002/jbmr.4869.
  PUBMED    37329499
REFERENCE   2  (bases 1 to 1593)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "J Bone 
            Miner Res. 2023 Jun 17. doi: 10.1002/jbmr.4869."
COMMENT     Sequence Label: ACVR1-VASS-R206H
FEATURES             Location/Qualifiers
     source          1..1593
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             1546..1593
                     /codon_start=1
                     /product="two tandem FLAG(R) epitope tags"
                     /label=2xFLAG
                     /translation="DYKDDDDKDYKDDDDK"
ORIGIN
        1 atggtagatg gagtgatgat tcttcctgtg cttatcatga ttgctctccc ctcccctagt
       61 atggaagatg agaagcccaa ggtcaacccc aaactctaca tgtgtgtgtg tgaaggtctc
      121 tcctgcggta atgaggacca ctgtgaaggc cagcagtgct tttcctcact gagcatcaac
      181 gatggcttcc acgtctacca gaaaggctgc ttccaggttt atgagcaggg aaagatgacc
      241 tgtaagaccc cgccgtcccc tggccaagct gtggagtgct gccaagggga ctggtgtaac
      301 aggaacatca cggcccagct gcccactaaa ggaaaatcct tccctggaac acagaatttc
      361 cacttggagg ttggcctcat tattctctct gtagtgttcg cagtatgtct tttagcctgc
      421 ctgctgggag ttgctctccg aaaatttaaa rggcgcaacc aagaacgcct caatccccga
      481 gacgtggagt atggcactat cgaagggctc atcaccacca atgttggaga cagcacttta
      541 gcagatttat tggatcattc gtgtgtagca ggaagtggct ctggtcttcc ttttctggta
      601 caaagaacag tggctcacca gattacactg ttggagtgtg tcgggaaagg caggtatggt
      661 gaggtgtgga ggggcagctg gcaaggggaa aatgttgccg tgaagatctt ctcctcccgt
      721 gatgagaagt catggttcag ggaaacggaa ttgtacaaca ctgtgatgct gaggcatgaa
      781 aatatcttag gtttcattgc ttcagacatg acatcaagac actccagtac ccagctgtgg
      841 ttaattacac attatcatga aatgggatcg ttgtacgact atcttcagct tactactctg
      901 gatacagtta gctgccttcg aatagtgctg tccatagcta gtggtcttgc acatttgcac
      961 atagagatat ttgggaccca agggaaacca gccattgccc atcgagattt aaagagcaaa
     1021 aatattctgg ttaagaagaa tggacagtgt tgcatagcag atttgggcct ggcagtcatg
     1081 cattcccaga gcaccaatca gcttgatgtg gggaacaatc cccgtgtggg caccaagcgc
     1141 tacatggccc ccgaagttct agatgaaacc atccaggtgg attgtttcga ttcttataaa
     1201 agggtcgata tttgggcctt tggacttgtt ttgtgggaag tggccaggcg gatggtgagc
     1261 aatggtatag tggaggatta caagccaccg ttctacgatg tggttcccaa tgacccaagt
     1321 tttgaagata tgaggaaggt agtctgtgtg gatcaacaaa ggccaaacat acccaacaga
     1381 tggttctcag acccgacatt aacctctctg gccaagctaa tgaaagaatg ctggtatcaa
     1441 aatccatccg caagactcac agcactgcgt atcaaaaaga ctttgaccaa aattgataat
     1501 tccctcgaca aattgaaaac tgactgtaat cgatttaaag ctatggatta caaggatgat
     1561 gatgataagg attacaagga tgatgatgat aag
//
