LOCUS       sequence-402706-        1596 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  in vitro transcription of RNA encoding human ACVR1 with mutations 
            T189V, S192A, and R206H.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1596)
  AUTHORS   Allen RS, Jones WD, Hale M, Warder BN, Shore EM, Mullins MC
  TITLE     Reduced GS domain serine/threonine requirements of Fibrodysplasia 
            Ossificans Progressiva mutant type I BMP receptor ACVR1 in the 
            zebrafish.
  JOURNAL   J Bone Miner Res. 2023 Jun 17. doi: 10.1002/jbmr.4869.
  PUBMED    37329499
REFERENCE   2  (bases 1 to 1596)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "J Bone 
            Miner Res. 2023 Jun 17. doi: 10.1002/jbmr.4869."
COMMENT     Sequence Label: ACVR1-VSAS-R206H
FEATURES             Location/Qualifiers
     source          1..1596
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             1549..1596
                     /codon_start=1
                     /product="two tandem FLAG(R) epitope tags"
                     /label=2xFLAG
                     /translation="DYKDDDDKDYKDDDDK"
ORIGIN
        1 tccatggtag atggagtgat gattcttcct gtgcttatca tgattgctct cccctcccct
       61 agtatggaag atgagaagcc caaggtcaac cccaaactct acatgtgtgt gtgtgaaggt
      121 ctctcctgcg gtaatgagga ccactgtgaa ggccagcagt gcttttcctc actgagcatc
      181 aacgatggct tccacgtcta ccagaaaggc tgcttccagg tttatgagca gggaaagatg
      241 acctgtaaga ccccgccgtc ccctggccaa gctgtggagt gctgccaagg ggactggtgt
      301 aacaggaaca tcacggccca gctgcccact aaaggaaaat ccttccctgg aacacagaat
      361 ttccacttgg aggttggcct cattattctc tctgtagtgt tcgcagtatg tcttttagcc
      421 tgcctgctgg gagttgctct ccgaaaattt aaarggcgca accaagaacg cctcaatccc
      481 cgagacgtgg agtatggcac tatcgaaggg ctcatcacca ccaatgttgg agacagcact
      541 ttagcagatt tattggatca ttcgtgtgta tcaggagctg gctctggtct tccttttctg
      601 gtacaaagaa cagtggctca ccagattaca ctgttggagt gtgtcgggaa aggcaggtat
      661 ggtgaggtgt ggaggggcag ctggcaaggg gaaaatgttg ccgtgaagat cttctcctcc
      721 cgtgatgaga agtcatggtt cagggaaacg gaattgtaca acactgtgat gctgaggcat
      781 gaaaatatct taggtttcat tgcttcagac atgacatcaa gacactccag tacccagctg
      841 tggttaatta cacattatca tgaaatggga tcgttgtacg actatcttca gcttactact
      901 ctggatacag ttagctgcct tcgaatagtg ctgtccatag ctagtggtct tgcacatttg
      961 cacatagaga tatttgggac ccaagggaaa ccagccattg cccatcgaga tttaaagagc
     1021 aaaaatattc tggttaagaa gaatggacag tgttgcatag cagatttggg cctggcagtc
     1081 atgcattccc agagcaccaa tcagcttgat gtggggaaca atccccgtgt gggcaccaag
     1141 cgctacatgg cccccgaagt tctagatgaa accatccagg tggattgttt cgattcttat
     1201 aaaagggtcg atatttgggc ctttggactt gttttgtggg aagtggccag gcggatggtg
     1261 agcaatggta tagtggagga ttacaagcca ccgttctacg atgtggttcc caatgaccca
     1321 agttttgaag atatgaggaa ggtagtctgt gtggatcaac aaaggccaaa catacccaac
     1381 agatggttct cagacccgac attaacctct ctggccaagc taatgaaaga atgctggtat
     1441 caaaatccat ccgcaagact cacagcactg cgtatcaaaa agactttgac caaaattgat
     1501 aattccctcg acaaattgaa aactgactgt aatcgattta aagctatgga ttacaaggat
     1561 gatgatgata aggattacaa ggatgatgat gataag
//
