LOCUS       sequence-402708-        1590 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  in vitro transcription of RNA encoding human ACVR1 with mutations 
            S190A, S192A, and R206H.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1590)
  AUTHORS   Allen RS, Jones WD, Hale M, Warder BN, Shore EM, Mullins MC
  TITLE     Reduced GS domain serine/threonine requirements of Fibrodysplasia 
            Ossificans Progressiva mutant type I BMP receptor ACVR1 in the 
            zebrafish.
  JOURNAL   J Bone Miner Res. 2023 Jun 17. doi: 10.1002/jbmr.4869.
  PUBMED    37329499
REFERENCE   2  (bases 1 to 1590)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "J Bone 
            Miner Res. 2023 Jun 17. doi: 10.1002/jbmr.4869."
COMMENT     Sequence Label: ACVR1-TAAS-R206H
FEATURES             Location/Qualifiers
     source          1..1590
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             1544..1567
                     /codon_start=1
                     /product="FLAG(R) epitope tag, followed by an enterokinase 
                     cleavage site"
                     /label=FLAG
                     /translation="DYKDDDDK"
ORIGIN
        1 ggtagatgga gtgatgattc ttcctgtgct tatcatgatt gctctcccct cccctagtat
       61 ggaagatgag aagcccaagg tcaaccccaa actctacatg tgtgtgtgtg aaggtctctc
      121 ctgcggtaat gaggaccact gtgaaggcca gcagtgcttt tcctcactga gcatcaacga
      181 tggcttccac gtctaccaga aaggctgctt ccaggtttat gagcagggaa agatgacctg
      241 taagaccccg ccgtcccctg gccaagctgt ggagtgctgc caaggggact ggtgtaacag
      301 gaacatcacg gcccagctgc ccactaaagg aaaatccttc cctggaacac agaatttcca
      361 cttggaggtt ggcctcatta ttctctctgt agtgttcgca gtatgtcttt tagcctgcct
      421 gctgggagtt gctctccgaa aatttaaarg gcgcaaccaa gaacgcctca atccccgaga
      481 cgtggagtat ggcactatcg aagggctcat caccaccaat gttggagaca gcactttagc
      541 agatttattg gatcattcgt gtacagcagg agctggctct ggtcttcctt ttctggtaca
      601 aagaacagtg gctcaccaga ttacactgtt ggagtgtgtc gggaaaggca ggtatggtga
      661 ggtgtggagg ggcagctggc aaggggaaaa tgttgccgtg aagatcttct cctcccgtga
      721 tgagaagtca tggttcaggg aaacggaatt gtacaacact gtgatgctga ggcatgaaaa
      781 tatcttaggt ttcattgctt cagacatgac atcaagacac tccagtaccc agctgtggtt
      841 aattacacat tatcatgaaa tgggatcgtt gtacgactat cttcagctta ctactctgga
      901 tacagttagc tgccttcgaa tagtgctgtc catagctagt ggtcttgcac atttgcacat
      961 agagatattt gggacccaag ggaaaccagc cattgcccat cgagatttaa agagcaaaaa
     1021 tattctggtt aagaagaatg gacagtgttg catagcagat ttgggcctgg cagtcatgca
     1081 ttcccagagc accaatcagc ttgatgtggg gaacaatccc cgtgtgggca ccaagcgcta
     1141 catggccccc gaagttctag atgaaaccat ccaggtggat tgtttcgatt cttataaaag
     1201 ggtcgatatt tgggcctttg gacttgtttt gtgggaagtg gccaggcgga tggtgagcaa
     1261 tggtatagtg gaggattaca agccaccgtt ctacgatgtg gttcccaatg acccaagttt
     1321 tgaagatatg aggaaggtag tctgtgtgga tcaacaaagg ccaaacatac ccaacagatg
     1381 gttctcagac ccgacattaa cctctctggc caagctaatg aaagaatgct ggtatcaaaa
     1441 tccatccgca agactcacag cactgcgtat caaaaagact ttgaccaaaa ttgataattc
     1501 cctcgacaaa ttgaaaactg actgtaatcg atttaaagct atggattaca aggatgatga
     1561 tgataaggat tacaaggatg atgatgataa
//
