LOCUS       sequence-411382-        2121 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Mammalian expression of full-length human FBXW7. C-terminal NanoLuc 
            luciferase tag..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2121)
  AUTHORS   Ackloo S, Li F, Szewczyk M, Seitova A, Loppnau P, Zeng H, Xu J, 
            Ahmad S, Arnautova YA, Baghaie AJ, Beldar S, Bolotokova A, Centrella
            PA, Chau I, Clark MA, Cuozzo JW, Dehghani-Tafti S, Disch JS, Dong A,
            Dumas A, Feng JA, Ghiabi P, Gibson E, Gilmer J, Goldman B, Green SR,
            Guie MA, Guilinger JP, Harms N, Herasymenko O, Houliston S, 
            Hutchinson A, Kearnes S, Keefe AD, Kimani SW, Kramer T, Kutera M, 
            Kwak HA, Lento C, Li Y, Liu J, Loup J, Machado RAC, Mulhern CJ, 
            Perveen S, Righetto GL, Riley P, Shrestha S, Sigel EA, Silva M, 
            Sintchak MD, Slakman BL, Taylor RD, Thompson J, Torng W, 
            Underkoffler C, von Rechenberg M, Walsh RT, Watson I, Wilson DJ, 
            Wolf E, Yadav M, Yazdi AK, Zhang J, Zhang Y, Santhakumar V, Edwards 
            AM, Barsyte-Lovejoy D, Schapira M, Brown PJ, Halabelian L, 
            Arrowsmith CH
  TITLE     A Target Class Ligandability Evaluation of WD40 Repeat-Containing 
            Proteins.
  JOURNAL   J Med Chem. 2025 Jan 23;68(2):1092-1112. doi: 
            10.1021/acs.jmedchem.4c02010. Epub 2024 Nov 4.
  PUBMED    39495097
REFERENCE   2  (bases 1 to 2121)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1021/acs.jmedchem.4c02010"; journalName: "J Med Chem"; date: 
            "2025-01-23- 23"; volume: "68"; issue: "2"; pages: "1092-1112"
COMMENT     Sequence Label: pNLF1-C_FBXW7:1-707
FEATURES             Location/Qualifiers
     source          1..2121
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgaatcagg aactgctctc tgtgggcagc aaaagacgac gaactggagg ctctctgaga
       61 ggtaaccctt cctcaagcca ggtagatgaa gaacagatga atcgtgtggt agaggaggaa
      121 cagcaacagc aactcagaca acaagaggag gagcacactg caaggaatgg tgaagttgtt
      181 ggagtagaac ctagacctgg aggccaaaat gattcccagc aaggacagtt ggaagaaaac
      241 aataatagat ttatttcggt agatgaggac tcctcaggaa accaagaaga acaagaggaa
      301 gatgaagaac atgctggtga acaagatgag gaggatgagg aggaggagga gatggaccag
      361 gagagtgacg attttgatca gtctgatgat agtagcagag aagatgaaca tacacatact
      421 aacagtgtca cgaactccag tagtattgtg gacctgcccg ttcaccaact ctcctcccca
      481 ttctatacaa aaacaacaaa aatgaaaaga aagttggacc atggttctga ggtccgctct
      541 ttttctttgg gaaagaaacc atgcaaagtc tcagaatata caagtaccac tgggcttgta
      601 ccatgttcag caacaccaac aacttttggg gacctcagag cagccaatgg ccaagggcaa
      661 caacgacgcc gaattacatc tgtccagcca cctacaggcc tccaggaatg gctaaaaatg
      721 tttcagagct ggagtggacc agagaaattg cttgctttag atgaactcat tgatagttgt
      781 gaaccaacac aagtaaaaca tatgatgcaa gtgatagaac cccagtttca acgagacttc
      841 atttcattgc tccctaaaga gttggcactc tatgtgcttt cattcctgga acccaaagac
      901 ctgctacaag cagctcagac atgtcgctac tggagaattt tggctgaaga caaccttctc
      961 tggagagaga aatgcaaaga agaggggatt gatgaaccat tgcacatcaa gagaagaaaa
     1021 gtaataaaac caggtttcat acacagtcca tggaaaagtg catacatcag acagcacaga
     1081 attgatacta actggaggcg aggagaactc aaatctccta aggtgctgaa aggacatgat
     1141 gatcatgtga tcacatgctt acagttttgt ggtaaccgaa tagttagtgg ttctgatgac
     1201 aacactttaa aagtttggtc agcagtcaca ggcaaatgtc tgagaacatt agtgggacat
     1261 acaggtggag tatggtcatc acaaatgaga gacaacatca tcattagtgg atctacagat
     1321 cggacactca aagtgtggaa tgcagagact ggagaatgta tacacacctt atatgggcat
     1381 acttccactg tgcgttgtat gcatcttcat gaaaaaagag ttgttagcgg ttctcgagat
     1441 gccactctta gggtttggga tattgagaca ggccagtgtt tacatgtttt gatgggtcat
     1501 gttgcagcag tccgctgtgt tcaatatgat ggcaggaggg ttgttagtgg agcatatgat
     1561 tttatggtaa aggtgtggga tccagagact gaaacctgtc tacacacgtt gcaggggcat
     1621 actaatagag tctattcatt acagtttgat ggtatccatg tggtgagtgg atctcttgat
     1681 acatcaatcc gtgtttggga tgtggagaca gggaattgca ttcacacgtt aacagggcac
     1741 cagtcgttaa caagtggaat ggaactcaaa gacaatattc ttgtctctgg gaatgcagat
     1801 tctacagtta aaatctggga tatcaaaaca ggacagtgtt tacaaacatt gcaaggtccc
     1861 aacaagcatc agagtgctgt gacctgttta cagttcaaca agaactttgt aattaccagc
     1921 tcagatgatg gaactgtaaa actatgggac ttgaaaacgg gtgaatttat tcgaaaccta
     1981 gtcacattgg agagtggggg gagtggggga gttgtgtggc ggatcagagc ctcaaacaca
     2041 aagctggtgt gtgcagttgg gagtcggaat gggactgaag aaaccaagct gctggtgctg
     2101 gactttgatg tggacatgaa g
//
