LOCUS       sequence-411448-        2811 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Mammalian expression of full-length human SMCR8. N-terminal 
            HaloTag..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2811)
  AUTHORS   Ackloo S, Li F, Szewczyk M, Seitova A, Loppnau P, Zeng H, Xu J, 
            Ahmad S, Arnautova YA, Baghaie AJ, Beldar S, Bolotokova A, Centrella
            PA, Chau I, Clark MA, Cuozzo JW, Dehghani-Tafti S, Disch JS, Dong A,
            Dumas A, Feng JA, Ghiabi P, Gibson E, Gilmer J, Goldman B, Green SR,
            Guie MA, Guilinger JP, Harms N, Herasymenko O, Houliston S, 
            Hutchinson A, Kearnes S, Keefe AD, Kimani SW, Kramer T, Kutera M, 
            Kwak HA, Lento C, Li Y, Liu J, Loup J, Machado RAC, Mulhern CJ, 
            Perveen S, Righetto GL, Riley P, Shrestha S, Sigel EA, Silva M, 
            Sintchak MD, Slakman BL, Taylor RD, Thompson J, Torng W, 
            Underkoffler C, von Rechenberg M, Walsh RT, Watson I, Wilson DJ, 
            Wolf E, Yadav M, Yazdi AK, Zhang J, Zhang Y, Santhakumar V, Edwards 
            AM, Barsyte-Lovejoy D, Schapira M, Brown PJ, Halabelian L, 
            Arrowsmith CH
  TITLE     A Target Class Ligandability Evaluation of WD40 Repeat-Containing 
            Proteins.
  JOURNAL   J Med Chem. 2025 Jan 23;68(2):1092-1112. doi: 
            10.1021/acs.jmedchem.4c02010. Epub 2024 Nov 4.
  PUBMED    39495097
REFERENCE   2  (bases 1 to 2811)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1021/acs.jmedchem.4c02010"; journalName: "J Med Chem"; date: 
            "2025-01-23- 23"; volume: "68"; issue: "2"; pages: "1092-1112"
COMMENT     Sequence Label: pHTN-HaloTag_SMCR8:1-937
FEATURES             Location/Qualifiers
     source          1..2811
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgatcagcg cccctgacgt agtggccttc accaaagagg aagagtatga agaagagcct
       61 tacaatgagc cggccctgcc tgaggagtac tcggtgccgc tcttcccctt cgccagtcag
      121 ggtgctaacc cctggtcaaa actgtccggg gccaagtttt cgagggactt cattcttatt
      181 tccgagttct ctgagcaggt gggaccccaa cccttactga ccatccccaa tgacaccaaa
      241 gtttttggca cttttgatct caattacttc tccctgcgta tcatgtctgt ggattaccag
      301 gcttccttcg tgggccatcc tcctggatct gcctacccca agctgaactt cgtggaggac
      361 tccaaggtgg tgctgggaga ttctaaggag ggcgcctttg catacgtgca ccaccttacc
      421 ctatacgacc tggaggcccg tggcttcgtg aggccgtttt gcatggctta tatctctgca
      481 gaccagcata aaatcatgca gcagttccag gagctttcag ccgaattttc cagagcttct
      541 gagtgcttga agactggcaa caggaaggca tttgctgggg aacttgaaaa aaagctgaaa
      601 gacttggatt acaccaggac agtgctacac acagaaacgg agatccagaa gaaagccaac
      661 gacaaaggct tttactcatc tcaggcaatt gagaaagcca atgaactggc cagtgtggag
      721 aagtccatca ttgaacatca agacctgctg aagcagatcc gctcataccc tcatcggaag
      781 ttgaaggggc atgatttgtg tcctggtgag atggagcaca tccaggatca ggccagccag
      841 gcatccacta cctctaaccc tgatgagtct gccgacacag acctttacac ctgcagacca
      901 gcctacaccc caaaacttat caaagcaaag tccaccaagt gttttgacaa gaagttgaag
      961 accttggagg agctctgtga cactgaatat ttcacccaga ccctggctca gctcagccac
     1021 attgaacaca tgttcagagg agacctgtgt tacctcctga ccagtcagat tgatagagca
     1081 cttctaaaac aacagcatat aacaaacttt ctctttgaag actttgtgga ggtcgatgac
     1141 aggatggtgg agaaacaaga aagcataccc tctaagccca gtcaagacag gccgccttcc
     1201 agttctctag aagaatgccc aattcctaaa gtgttaatta gtgttggttc ttacaagtcc
     1261 agtgtggagt ctgtgttgat caagatggag caggaactgg gagatgagga gtacaaggaa
     1321 gtggaagtga ctgagttgag cagtttcgac ccccaggaaa acttggacta cctggatatg
     1381 gatatgaaag ggagtatcag cagtggtgaa agtattgaag ttttgggcac ggagaaatcc
     1441 acctccgtgc tttctaaatc tgacagccag gcaagcctca cagtaccatt gagcccccag
     1501 gtggtccgga gcaaagcagt cagccacagg accatcagcg aggacagtat tgaagtcctc
     1561 agtacctgcc cctctgaggc cctcatccct gatgacttta aggccagcta cccaagtgcc
     1621 attaatgaag aagaatcata tccagatggc aatgaaggag ccatccgctt ccaggcaagc
     1681 atcagtcctc cagaactggg tgagacagag gaaggcagca tagaaaacac cccatcacaa
     1741 atagactcct cctgctgtat tgggaaggag agcgatggtc agttggtgct gccctccact
     1801 ccagcccaca cacactctga cgaggatggg gtggtgagca gccccccaca gcgccacagg
     1861 cagaaggacc aggggttccg tgtagacttt tcagtggaaa atgccaaccc ttcttcccga
     1921 gacaacagtt gtgaagggtt tcccgcttat gagctggacc cgagccacct gctggctagc
     1981 cgggacatca gtaagaccag cctggacaac tactcagaca ccaccagcta cgtgagcagt
     2041 gtagcgtcca ccagctcaga caggatcccc tctgcttatc ctgctggcct gtcttccgat
     2101 aggcataaaa agagggctgg ccagaacgcc ttaaaattca tccgccagta cccctttgcc
     2161 cacccagcca tctactccct gctcagtggg aggacacttg tggtcctggg ggaagatgag
     2221 gccatagtca ggaaactcgt gactgcactg gctatctttg tccccagcta tggctgctac
     2281 gctaagcccg tgaaacattg ggcctcctcc cctttgcaca ttatggattt tcagaagtgg
     2341 aagcttattg gcttgcagag agtggcctcc cctgccggtg ccggtaccct ccatgccctg
     2401 agccgctaca gccgctacac gagcatcctg gaccttgaca acaaaaccct gcgctgcccc
     2461 ctttacagag gcaccctggt gccccgcctg gcagaccacc gcacacagat caagcggggc
     2521 agcacctact acctgcatgt ccagagcatg ctcacccagc tctgctccaa ggccttcctc
     2581 tacaccttct gccaccacct gcacctgcct acccacgaca aggagacaga ggagctggta
     2641 gccagccgcc agatgagctt cctaaagctg accctgggtc tggtgaatga ggatgttagg
     2701 gtggtccagt acctggctga gctgctgaag ctgcactaca tgcaggaatc tccagggacc
     2761 agccacccca tgctcaggtt tgactatgtc cccagctttt tgtataaaat c
//
