LOCUS       sequence-411484-        2661 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Mammalian expression of human WDR81 fragment M728 to S1614. 
            N-terminal NanoLuc luciferase tag..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2661)
  AUTHORS   Ackloo S, Li F, Szewczyk M, Seitova A, Loppnau P, Zeng H, Xu J, 
            Ahmad S, Arnautova YA, Baghaie AJ, Beldar S, Bolotokova A, Centrella
            PA, Chau I, Clark MA, Cuozzo JW, Dehghani-Tafti S, Disch JS, Dong A,
            Dumas A, Feng JA, Ghiabi P, Gibson E, Gilmer J, Goldman B, Green SR,
            Guie MA, Guilinger JP, Harms N, Herasymenko O, Houliston S, 
            Hutchinson A, Kearnes S, Keefe AD, Kimani SW, Kramer T, Kutera M, 
            Kwak HA, Lento C, Li Y, Liu J, Loup J, Machado RAC, Mulhern CJ, 
            Perveen S, Righetto GL, Riley P, Shrestha S, Sigel EA, Silva M, 
            Sintchak MD, Slakman BL, Taylor RD, Thompson J, Torng W, 
            Underkoffler C, von Rechenberg M, Walsh RT, Watson I, Wilson DJ, 
            Wolf E, Yadav M, Yazdi AK, Zhang J, Zhang Y, Santhakumar V, Edwards 
            AM, Barsyte-Lovejoy D, Schapira M, Brown PJ, Halabelian L, 
            Arrowsmith CH
  TITLE     A Target Class Ligandability Evaluation of WD40 Repeat-Containing 
            Proteins.
  JOURNAL   J Med Chem. 2025 Jan 23;68(2):1092-1112. doi: 
            10.1021/acs.jmedchem.4c02010. Epub 2024 Nov 4.
  PUBMED    39495097
REFERENCE   2  (bases 1 to 2661)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1021/acs.jmedchem.4c02010"; journalName: "J Med Chem"; date: 
            "2025-01-23- 23"; volume: "68"; issue: "2"; pages: "1092-1112"
COMMENT     Sequence Label: pNLF1-N_WDR81:728-1614
FEATURES             Location/Qualifiers
     source          1..2661
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgcaggcct tggaggagct ggaaaaaaca ggaaacttcc ttgctaaggg ccttggcggc
       61 ctgctggagg tcccagagca gcctagggta cagcccgcgg tacccttgca gtgcctgttg
      121 caccgagaca tgcaggcctt gggtgtcctc ctcgcggaaa tggtgtttgc gacgcgagtc
      181 cgaacgctcc aacctgacgc tcctttgtgg gtgcgctttc aggcagtgcg cggactttgt
      241 acacggcacc cgaaggaggt gccagtttcc cttcagcctg tattggatac attgttgcag
      301 atgtccggac cggaggttcc catgggtgcc gagcggggta agcttgacca attgttcgag
      361 tatcgaccgg tgagtcaagg acttccaccc ccatgcccat cacagctgct gtcccccttt
      421 agctcagtag ttcccttccc tccttatttc ccggcactgc ataggtttat tctgctttat
      481 caggctcgac gcgtcgagga tgaggcccaa ggccgggagt tggtattcgc cctctggcaa
      541 cagctgggcg ctgtgcttaa agacattacc ccagagggac ttgagatatt gctgcccttt
      601 gtcctcagcc ttatgtccga ggaacatacc gcggtgtata cagcctggta cctctttgag
      661 cctgttgcga aggctctggg acctaagaac gcaaataagt acctcctgaa acccctcata
      721 ggagcttatg agtccccttg ccaattgcac gggaggtttt atttgtatac agattgtttt
      781 gtggcccagc tcatggtaag attgggcctg caggcctttt tgacgcacct gttgccgcac
      841 gtactccaag tattggccgg agctgaagca tcacaggaag agtcaaagga tctggcggga
      901 gctgctgaag aagaagagtc cggtcttcca ggggcgggcc caggcagttg cgcatttgga
      961 gaggaaatcc cgatggatgg cgaacctcca gcgtcttcag gtctcggact cccagactat
     1021 acaagcgggg ttagcttcca cgatcaggct gacctccccg agaccgaaga tttccaagct
     1081 ggtctgtatg taaccgaaag tccacaaccg caagaagcgg aggcagtgtc cttgggtcga
     1141 ctcagcgaca aatcttctac atccgaaact tctctgggcg aggagagggc accggatgaa
     1201 ggaggggccc ctgttgacaa aagctcactt aggtccggag atagtagtca agatctcaaa
     1261 cagtctgaag gatccgaaga agaagaggag gaagaggatt cctgtgttgt gctggaggag
     1321 gaagagggag aacaggagga agttaccggc gcaagtgaac tgacacttag tgatacggtg
     1381 ctctcaatgg agaccgtagt cgccggtggc tcaggaggag acggggaaga ggaagaggag
     1441 gccctgccag aacaatcaga aggtaaagaa caaaagatcc tccttgacac cgcctgtaag
     1501 atggtccgct ggctctccgc taagttggga ccaacggttg cgagtcggca cgtggcgcgg
     1561 aatctcctga gactgctcac aagctgctac gttggcccta ctaggcaaca gttcacagtc
     1621 tcctctggag aatccccccc actctccgct ggaaacatct accagaagag accagtactg
     1681 ggtgacatcg tctctgggcc agtgttgagc tgcttgttgc acatcgcacg attgtatggc
     1741 gaaccggtac ttacgtatca atacctgcca tatatttctt acctcgtggc ccccggctca
     1801 gcttctgggc cctcccgcct caatagccga aaagaagcgg gtctgcttgc tgctgtcacg
     1861 ttgactcaaa aaattattgt ataccttagc gacacgacac tgatggacat cttgccaaga
     1921 atcagccatg aggtgctgct tccagtcttg tcatttttga ccagtcttgt tacggggttt
     1981 ccgtccggtg cccaagcaag gactatcctt tgtgtaaaaa caatatcatt gatagcactc
     2041 atttgcctta ggattggaca ggagatggta caacaacatt tgtccgaacc cgtagctact
     2101 tttttccaag tctttagtca gctgcacgag ctccgccagc aggacttgaa gttggatcct
     2161 gctggtaggg gagagggcca actgccccag gtcgttttca gcgatgggca acaaaggcca
     2221 gtcgacccgg ccctcctgga tgaactccaa aaagttttca ccctggaaat ggcctacacg
     2281 atatacgtgc ctttttcatg ccttttgggt gatataatca gaaaaattat ccctaatcat
     2341 gaactcgttg gagaacttgc tgccctgtat cttgaaagca tttcacccag ttcaaggaat
     2401 ccagcaagtg ttgaaccgac aatgcctggt acgggacccg agtgggatcc tcatggtggt
     2461 ggctgcccgc aagacgacgg gcattctggt acattcggta gcgtccttgt cggcaatcgc
     2521 attcagatac ctaatgactc ccgccccgag aatcctggtc ctttgggacc gatatcaggg
     2581 gtgggtgggg gaggactcgg aagcggctcc gacgacaatg ccctcaaaca ggaactgcca
     2641 cgaagtgtcc acggcctgtc a
//
