LOCUS       sequence-411486-        2235 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Mammalian expression of human WDR81 fragment M1 to L745. N-terminal 
            NanoLuc luciferase tag..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2235)
  AUTHORS   Ackloo S, Li F, Szewczyk M, Seitova A, Loppnau P, Zeng H, Xu J, 
            Ahmad S, Arnautova YA, Baghaie AJ, Beldar S, Bolotokova A, Centrella
            PA, Chau I, Clark MA, Cuozzo JW, Dehghani-Tafti S, Disch JS, Dong A,
            Dumas A, Feng JA, Ghiabi P, Gibson E, Gilmer J, Goldman B, Green SR,
            Guie MA, Guilinger JP, Harms N, Herasymenko O, Houliston S, 
            Hutchinson A, Kearnes S, Keefe AD, Kimani SW, Kramer T, Kutera M, 
            Kwak HA, Lento C, Li Y, Liu J, Loup J, Machado RAC, Mulhern CJ, 
            Perveen S, Righetto GL, Riley P, Shrestha S, Sigel EA, Silva M, 
            Sintchak MD, Slakman BL, Taylor RD, Thompson J, Torng W, 
            Underkoffler C, von Rechenberg M, Walsh RT, Watson I, Wilson DJ, 
            Wolf E, Yadav M, Yazdi AK, Zhang J, Zhang Y, Santhakumar V, Edwards 
            AM, Barsyte-Lovejoy D, Schapira M, Brown PJ, Halabelian L, 
            Arrowsmith CH
  TITLE     A Target Class Ligandability Evaluation of WD40 Repeat-Containing 
            Proteins.
  JOURNAL   J Med Chem. 2025 Jan 23;68(2):1092-1112. doi: 
            10.1021/acs.jmedchem.4c02010. Epub 2024 Nov 4.
  PUBMED    39495097
REFERENCE   2  (bases 1 to 2235)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1021/acs.jmedchem.4c02010"; journalName: "J Med Chem"; date: 
            "2025-01-23- 23"; volume: "68"; issue: "2"; pages: "1092-1112"
COMMENT     Sequence Label: pNLF1-N_WDR81:1-745
FEATURES             Location/Qualifiers
     source          1..2235
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggcacagg gctctggggg tcgagaaggt gcactccgga cgcctgctgg tggatggcac
       61 agcccgcctt cccctgacat gcaggaattg cttcgctccg tagaaaggga tctctctata
      121 gatccacgcc agcttgcgcc ggcacctgga ggtacgcatg tcgtagccct ggtaccggcc
      181 aggtggctcg ccagtctgag agatagacga ctcccattgg gaccttgccc cagggctgag
      241 ggacttggtg aggcggaggt gcgaaccttg ctgcagaggt ctgtccagag gcttcctgcg
      301 ggttggacaa gggtagaggt gcacggtctc cgaaaacggc ggttgtccta tccgctgggt
      361 ggtggcctcc cttttgagga cggaagttgc ggccctgaaa ctctcacccg gtttatgcaa
      421 gaagtagccg cacaaaacta ccgaaatctg tggaggcatg cttatcatac gtacgggcaa
      481 ccgtattccc attcccctgc gccgagcgca gtacccgcac tggatagtgt gcgacaagct
      541 cttcagcggg tttatggttg ttcttttttg cccgttggcg aaacgacgca atgcccctct
      601 tacgctcgag agggaccttg tcctccacga gggagccctg cctgtccttc cttgttgcgg
      661 gcagaggctc tcctcgagag tccggagatg ctgtatgttg tgcaccctta cgtgcagttt
      721 agcctgcatg atgtggtgac cttcagccca gcaaagttga ctaatagtca ggcaaaagtg
      781 ctctttatct tgtttcgagt cctgcgagcc atggacgctt gccaccggca aggtctcgcc
      841 tgcggtgcat tgtctcttta ccatattgcc gtcgatgaga agctctgcag tgagcttaga
      901 ttggatctga gtgcttacga acggcctgag gaggacgaga atgaggaggc cccagtggcg
      961 cgagacgaag cgggtatcgt atcccaagag gagcagggtg gccaacccgg tcaacccacg
     1021 ggtcaagaag agcttagatc tctcgtgctt gactgggtcc acggcagaat ctccaacttc
     1081 cactatttga tgcaactcaa cagactggcg gggcggaggc agggtgaccc gaattaccat
     1141 ccagtcctgc cgtgggtggt agatttcaca accccacatg gtcggttccg agacctccgg
     1201 aaatctaagt tcaggttgaa caagggcgat aagcaactgg actttaccta tgaaatgact
     1261 cggcaggcct ttgtagcggg cggagcaggg gggggagagc ctccccacgt gccgcatcat
     1321 atctcagatg tcctgtccga catcacctac tatgtgtaca aagccagaag gactcctcgg
     1381 tctgttttgt gtggacacgt tcgcgcccaa tgggaacccc atgaatatcc agcgtcaatg
     1441 gagcgaatgc agaattggac gccagacgaa tgtattcctg agttctacac cgacccgagt
     1501 atatttcgat ctattcaccc cgatatgcct gacttggatg tgcccgcatg gtgctcaagt
     1561 agccaggagt tcgtagctgc ccatcgcgcc ttgttggaat cacgggaagt aagccgggat
     1621 ctgcaccatt ggattgacct tacattcgga tacaaattgc agggtaaaga ggcagttaag
     1681 gaaaagaacg tttgtcttca tctggttgac gcacacacgc atcttgcgtc ctacggggtt
     1741 gtccaattgt tcgatcaacc ccatccgcaa aggctcgctg gcgccccagc tcttgcccca
     1801 gaaccgccgc ttatacctaa acttctggtg cagacgatac aagaaaccac tggtcgagag
     1861 gattttaccg aaaatcctgg gcaattgccc aacggagtcg gcagaccagt attggaagca
     1921 accccctgtg aagcttcttg gactagggat agacctgtgg ccggtgaaga tgacctggag
     1981 caagccaccg aagcactgga tagtataagc ctcgcgggaa aggccgggga ccagctcgga
     2041 agcagctctc aagccagtcc tggcctcctc agcttttcag tcgcgagtgc ctcaagacct
     2101 gggcggcgca acaaagccgc cggtgccgac ccaggcgaag gggaggaagg gaggatattg
     2161 cttccagaag ggttcaatcc tatgcaggcc ttggaggagc tggaaaaaac aggaaacttc
     2221 cttgctaagg gcctt
//
