LOCUS       sequence-411498-        2217 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Mammalian expression of full-length human SUZ12. N-terminal 
            HaloTag..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2217)
  AUTHORS   Ackloo S, Li F, Szewczyk M, Seitova A, Loppnau P, Zeng H, Xu J, 
            Ahmad S, Arnautova YA, Baghaie AJ, Beldar S, Bolotokova A, Centrella
            PA, Chau I, Clark MA, Cuozzo JW, Dehghani-Tafti S, Disch JS, Dong A,
            Dumas A, Feng JA, Ghiabi P, Gibson E, Gilmer J, Goldman B, Green SR,
            Guie MA, Guilinger JP, Harms N, Herasymenko O, Houliston S, 
            Hutchinson A, Kearnes S, Keefe AD, Kimani SW, Kramer T, Kutera M, 
            Kwak HA, Lento C, Li Y, Liu J, Loup J, Machado RAC, Mulhern CJ, 
            Perveen S, Righetto GL, Riley P, Shrestha S, Sigel EA, Silva M, 
            Sintchak MD, Slakman BL, Taylor RD, Thompson J, Torng W, 
            Underkoffler C, von Rechenberg M, Walsh RT, Watson I, Wilson DJ, 
            Wolf E, Yadav M, Yazdi AK, Zhang J, Zhang Y, Santhakumar V, Edwards 
            AM, Barsyte-Lovejoy D, Schapira M, Brown PJ, Halabelian L, 
            Arrowsmith CH
  TITLE     A Target Class Ligandability Evaluation of WD40 Repeat-Containing 
            Proteins.
  JOURNAL   J Med Chem. 2025 Jan 23;68(2):1092-1112. doi: 
            10.1021/acs.jmedchem.4c02010. Epub 2024 Nov 4.
  PUBMED    39495097
REFERENCE   2  (bases 1 to 2217)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1021/acs.jmedchem.4c02010"; journalName: "J Med Chem"; date: 
            "2025-01-23- 23"; volume: "68"; issue: "2"; pages: "1092-1112"
COMMENT     Sequence Label: pHTN-HaloTag_SUZ12:1-739
FEATURES             Location/Qualifiers
     source          1..2217
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggcgcctc agaagcacgg cggtggggga gggggcggct cggggcccag cgcggggtcc
       61 gggggaggcg gcttcggggg ttcggcggcg gtggcggcgg cgacggcttc gggcggcaaa
      121 tccggcggcg ggagctgtgg agggggtggc agttactcgg cctcctcctc ctcctccgcg
      181 gcggcagcgg cgggggctgc ggtgttaccg gtgaagaagc cgaaaatgga gcacgtccag
      241 gctgaccacg agcttttcct ccaggccttt gagaagccaa cacagatcta tagatttctt
      301 cgaactcgga atctcatagc accaatattt ttgcacagaa ctcttactta catgtctcat
      361 cgaaactcca gaacaaacat caaaaggaaa acatttaaag ttgatgatat gttatcaaaa
      421 gtagagaaaa tgaaaggaga gcaagaatct catagcttgt cagctcattt gcagcttacg
      481 tttactggtt tcttccacaa aaatgataag ccatcaccaa actcagaaaa tgaacaaaat
      541 tctgttaccc tggaagtcct gcttgtgaaa gtttgccaca aaaaaagaaa ggatgtaagt
      601 tgtccaataa ggcaagttcc cacaggtaaa aagcaggtgc ctttgaatcc tgacctcaat
      661 caaacaaaac ccggaaattt cccgtccctt gcagtttcca gtaatgaatt tgaacctagt
      721 aacagccata tggtgaagtc ttactcgttg ctatttagag tgactcgtcc aggaagaaga
      781 gagtttaatg gaatgattaa tggagaaacc aatgaaaata ttgatgtcaa tgaagagctt
      841 ccagccagaa gaaaacgaaa tcgtgaggat ggggaaaaga catttgttgc acaaatgaca
      901 gtatttgata aaaacaggcg cttacagctt ttagatgggg aatatgaagt agccatgcag
      961 gaaatggaag aatgtccaat aagcaagaaa agagcaacat gggagactat tcttgatggg
     1021 aagaggctgc ctccattcga aacattttct cagggaccta cgttgcagtt cactcttcgt
     1081 tggacaggag agaccaatga taaatctacg gctcctattg ccaaacctct tgccactaga
     1141 aattcagaga gtctccatca ggaaaacaag cctggttcag ttaaacctac tcaaactatt
     1201 gctgttaaag aatcattgac tacagatcta caaacaagaa aagaaaagga tactccaaat
     1261 gaaaaccgac aaaaattaag aatattttat cagtttctct ataacaacaa tacaaggcaa
     1321 caaactgaag caagagatga cctgcattgc ccttggtgta ctctgaactg ccgcaaactt
     1381 tatagtttac tcaagcatct taaactctgc catagcagat ttatcttcaa ctatgtttat
     1441 catccaaaag gtgctaggat agatgtttct atcaatgagt gttatgatgg ctcctatgca
     1501 ggaaatcctc aggatattca tcgccaacct ggatttgctt ttagtcgcaa cggaccagtt
     1561 aagagaacac ctatcacaca tattcttgtg tgcaggccaa aacgaacaaa agcaagcatg
     1621 tctgaatttc ttgaatctga agatggggaa gtagaacagc aaagaacata tagtagtggc
     1681 cacaatcgtc tgtatttcca tagtgatacc tgcttacctc tccgtccaca agaaatggaa
     1741 gtagatagtg aagatgaaaa ggatcctgaa tggctaagag aaaaaaccat tacacaaatt
     1801 gaagagtttt ctgatgttaa tgaaggagag aaagaagtga tgaaactctg gaatctccat
     1861 gtcatgaagc atgggtttat tgctgacaat caaatgaatc atgcctgtat gctgtttgta
     1921 gaaaattatg gacagaaaat aattaagaag aatttatgtc gaaacttcat gcttcatcta
     1981 gtcagcatgc atgactttaa tcttattagc ataatgtcaa tagataaagc tgttaccaag
     2041 ctccgtgaaa tgcagcaaaa attagaaaag ggggaatctg cttcccctgc aaacgaagaa
     2101 ataactgaag aacaaaatgg gacagcaaat ggatttagtg aaattaactc aaaagagaaa
     2161 gctttggaaa cagatagtgt ctcaggggtt tcaaaacaga gcaaaaaaca aaaactc
//
