LOCUS       sequence-411508-        2319 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Mammalian expression of full-length human BCL11A. N-terminal 
            HaloTag..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2319)
  AUTHORS   Ackloo S, Li F, Szewczyk M, Seitova A, Loppnau P, Zeng H, Xu J, 
            Ahmad S, Arnautova YA, Baghaie AJ, Beldar S, Bolotokova A, Centrella
            PA, Chau I, Clark MA, Cuozzo JW, Dehghani-Tafti S, Disch JS, Dong A,
            Dumas A, Feng JA, Ghiabi P, Gibson E, Gilmer J, Goldman B, Green SR,
            Guie MA, Guilinger JP, Harms N, Herasymenko O, Houliston S, 
            Hutchinson A, Kearnes S, Keefe AD, Kimani SW, Kramer T, Kutera M, 
            Kwak HA, Lento C, Li Y, Liu J, Loup J, Machado RAC, Mulhern CJ, 
            Perveen S, Righetto GL, Riley P, Shrestha S, Sigel EA, Silva M, 
            Sintchak MD, Slakman BL, Taylor RD, Thompson J, Torng W, 
            Underkoffler C, von Rechenberg M, Walsh RT, Watson I, Wilson DJ, 
            Wolf E, Yadav M, Yazdi AK, Zhang J, Zhang Y, Santhakumar V, Edwards 
            AM, Barsyte-Lovejoy D, Schapira M, Brown PJ, Halabelian L, 
            Arrowsmith CH
  TITLE     A Target Class Ligandability Evaluation of WD40 Repeat-Containing 
            Proteins.
  JOURNAL   J Med Chem. 2025 Jan 23;68(2):1092-1112. doi: 
            10.1021/acs.jmedchem.4c02010. Epub 2024 Nov 4.
  PUBMED    39495097
REFERENCE   2  (bases 1 to 2319)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1021/acs.jmedchem.4c02010"; journalName: "J Med Chem"; date: 
            "2025-01-23- 23"; volume: "68"; issue: "2"; pages: "1092-1112"
COMMENT     Sequence Label: pHTN-HaloTag_BCL11A:1-773
FEATURES             Location/Qualifiers
     source          1..2319
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             107..118
                     /codon_start=1
                     /product="WELQut protease recognition and cleavage site"
                     /label=WELQut site
                     /translation="WELQ"
ORIGIN
        1 atgtctcgcc gcaagcaagg caaaccccag cacttaagca aacgggaatt ctcgcccgag
       61 cctcttgaag ccattcttac agatgatgaa ccagaccacg gcccgttggg agctccagaa
      121 ggggatcatg acctcctcac ctgtgggcag tgccagatga acttcccatt gggggacatt
      181 cttattttta tcgagcacaa acggaaacaa tgcaatggca gcctctgctt agaaaaagct
      241 gtggataagc caccttcccc ttcaccaatc gagatgaaaa aagcatccaa tcccgtggag
      301 gttggcatcc aggtcacgcc agaggatgac gattgtttat caacgtcatc tagaggaatt
      361 tgccccaaac aggaacacat agcagataaa cttctgcact ggaggggcct ctcctcccct
      421 cgttctgcac atggagctct aatccccacg cctgggatga gtgcagaata tgccccgcag
      481 ggtatttgta aagatgagcc cagcagctac acatgtacaa cttgcaaaca gccattcacc
      541 agtgcatggt ttctcttgca acacgcacag aacactcatg gattaagaat ctacttagaa
      601 agcgaacacg gaagtcccct gaccccgcgg gttggtatcc cttcaggact aggtgcagaa
      661 tgtccttccc agccacctct ccatgggatt catattgcag acaataaccc ctttaacctg
      721 ctaagaatac caggatcagt atcgagagag gcttccggcc tggcagaagg gcgctttcca
      781 cccactcccc ccctgtttag tccaccaccg agacatcact tggaccccca ccgcatagag
      841 cgcctggggg cggaagagat ggccctggcc acccatcacc cgagtgcctt tgacagggtg
      901 ctgcggttga atccaatggc tatggagcct cccgccatgg atttctctag gagacttaga
      961 gagctggcag ggaacacgtc tagcccaccg ctgtccccag gccggcccag ccctatgcaa
     1021 aggttactgc aaccattcca gccaggtagc aagccgccct tcctggcgac gccccccctc
     1081 cctcctctgc aatccgcccc tcctccctcc cagcccccgg tcaagtccaa gtcatgcgag
     1141 ttctgcggca agacgttcaa atttcagagc aacctggtgg tgcaccggcg cagccacacg
     1201 ggcgagaagc cctacaagtg caacctgtgc gaccacgcgt gcacccaggc cagcaagctg
     1261 aagcgccaca tgaagacgca catgcacaaa tcgtccccca tgacggtcaa gtccgacgac
     1321 ggtctctcca ccgccagctc cccggaaccc ggcaccagcg acttggtggg cagcgccagc
     1381 agcgcgctca agtccgtggt ggccaagttc aagagcgaga acgaccccaa cctgatcccg
     1441 gagaacgggg acgaggagga agaggaggac gacgaggaag aggaagaaga ggaggaagag
     1501 gaggaggagg agctgacgga gagcgagagg gtggactacg gcttcgggct gagcctggag
     1561 gcggcgcgcc accacgagaa cagctcgcgg ggcgcggtcg tgggcgtggg cgacgagagc
     1621 cgcgccctgc ccgacgtcat gcagggcatg gtgctcagct ccatgcagca cttcagcgag
     1681 gccttccacc aggtcctggg cgagaagcat aagcgcggcc acctggccga ggccgagggc
     1741 cacagggaca cttgcgacga agactcggtg gccggcgagt cggaccgcat agacgatggc
     1801 actgttaatg gccgcggctg ctccccgggc gagtcggcct cggggggcct gtccaaaaag
     1861 ctgctgctgg gcagccccag ctcgctgagc cccttctcta agcgcatcaa gctcgagaag
     1921 gagttcgacc tgcccccggc cgcgatgccc aacacggaga acgtgtactc gcagtggctc
     1981 gccggctacg cggcctccag gcagctcaaa gatcccttcc ttagcttcgg agactccaga
     2041 caatcgcctt ttgcctcctc gtcggagcac tcctcggaga acgggagctt gcgcttctcc
     2101 acaccgcccg gggagctgga cggagggatc tcggggcgca gcggcacggg aagtggaggg
     2161 agcacgcccc atattagtgg tccgggcccg ggcaggccca gctcaaaaga gggcagacgc
     2221 agcgacactt gttcttcaca cacccccatt cggcgtagta cccagagagc tcaagatgtg
     2281 tggcagtttt cggatggaag ctcgagagcc cttaagttc
//
