LOCUS       sequence-411530-        1002 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Mammalian expression of full-length human WDR5. N-terminal NanoLuc 
            luciferase tag..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1002)
  AUTHORS   Ackloo S, Li F, Szewczyk M, Seitova A, Loppnau P, Zeng H, Xu J, 
            Ahmad S, Arnautova YA, Baghaie AJ, Beldar S, Bolotokova A, Centrella
            PA, Chau I, Clark MA, Cuozzo JW, Dehghani-Tafti S, Disch JS, Dong A,
            Dumas A, Feng JA, Ghiabi P, Gibson E, Gilmer J, Goldman B, Green SR,
            Guie MA, Guilinger JP, Harms N, Herasymenko O, Houliston S, 
            Hutchinson A, Kearnes S, Keefe AD, Kimani SW, Kramer T, Kutera M, 
            Kwak HA, Lento C, Li Y, Liu J, Loup J, Machado RAC, Mulhern CJ, 
            Perveen S, Righetto GL, Riley P, Shrestha S, Sigel EA, Silva M, 
            Sintchak MD, Slakman BL, Taylor RD, Thompson J, Torng W, 
            Underkoffler C, von Rechenberg M, Walsh RT, Watson I, Wilson DJ, 
            Wolf E, Yadav M, Yazdi AK, Zhang J, Zhang Y, Santhakumar V, Edwards 
            AM, Barsyte-Lovejoy D, Schapira M, Brown PJ, Halabelian L, 
            Arrowsmith CH
  TITLE     A Target Class Ligandability Evaluation of WD40 Repeat-Containing 
            Proteins.
  JOURNAL   J Med Chem. 2025 Jan 23;68(2):1092-1112. doi: 
            10.1021/acs.jmedchem.4c02010. Epub 2024 Nov 4.
  PUBMED    39495097
REFERENCE   2  (bases 1 to 1002)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1021/acs.jmedchem.4c02010"; journalName: "J Med Chem"; date: 
            "2025-01-23- 23"; volume: "68"; issue: "2"; pages: "1092-1112"
COMMENT     Sequence Label: pNLF1-N_WDR5:1-334
FEATURES             Location/Qualifiers
     source          1..1002
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggcgacgg aggagaagaa gcccgagacc gaggccgcca gagcacagcc aaccccttcg
       61 tcatccgcca ctcagagcaa gcctacacct gtgaagccaa actatgctct aaagttcacc
      121 cttgctggcc acaccaaagc agtgtcctcc gtgaaattca gcccgaatgg agagtggctg
      181 gcaagttcat ctgctgataa acttattaaa atttggggcg cgtatgatgg gaaatttgag
      241 aaaaccatat ctggtcacaa gctgggaata tccgatgtag cctggtcgtc agattctaac
      301 cttcttgttt ctgcctcaga tgacaaaacc ttgaagatat gggacgtgag ctcgggcaag
      361 tgtctgaaaa ccctgaaggg acacagtaat tatgtctttt gctgcaactt caatccccag
      421 tccaacctta ttgtctcagg atcctttgac gaaagcgtga ggatatggga tgtgaaaaca
      481 gggaagtgcc tcaagacttt gccagctcac tcggatccag tctcggccgt tcattttaat
      541 cgtgatggat ccttgatagt ttcaagtagc tatgatggtc tctgtcgcat ctgggacacc
      601 gcctcgggcc agtgcctgaa gacgctcatc gatgacgaca acccccccgt gtcttttgtg
      661 aagttctccc cgaacggcaa atacatcctg gccgccacgc tggacaacac tctgaagctc
      721 tgggactaca gcaaggggaa gtgcctgaag acgtacactg gccacaagaa tgagaaatac
      781 tgcatatttg ccaatttctc tgttactggt gggaagtgga ttgtgtctgg ctcagaggat
      841 aaccttgttt acatctggaa ccttcagacg aaagagattg tacagaaact acaaggccac
      901 acagatgtcg tgatctcaac agcttgtcac ccaacagaaa acatcatcgc ctctgctgcg
      961 ctagaaaatg acaaaacaat taaactgtgg aagagtgact gc
//
