LOCUS       sequence-411534-         999 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  bacterial expression of human WDR5 fragment A2 to C334. N-terminal 
            10X His tag with TEV cleavage and C-terminal biotin acceptor peptide
            tag..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 999)
  AUTHORS   Ackloo S, Li F, Szewczyk M, Seitova A, Loppnau P, Zeng H, Xu J, 
            Ahmad S, Arnautova YA, Baghaie AJ, Beldar S, Bolotokova A, Centrella
            PA, Chau I, Clark MA, Cuozzo JW, Dehghani-Tafti S, Disch JS, Dong A,
            Dumas A, Feng JA, Ghiabi P, Gibson E, Gilmer J, Goldman B, Green SR,
            Guie MA, Guilinger JP, Harms N, Herasymenko O, Houliston S, 
            Hutchinson A, Kearnes S, Keefe AD, Kimani SW, Kramer T, Kutera M, 
            Kwak HA, Lento C, Li Y, Liu J, Loup J, Machado RAC, Mulhern CJ, 
            Perveen S, Righetto GL, Riley P, Shrestha S, Sigel EA, Silva M, 
            Sintchak MD, Slakman BL, Taylor RD, Thompson J, Torng W, 
            Underkoffler C, von Rechenberg M, Walsh RT, Watson I, Wilson DJ, 
            Wolf E, Yadav M, Yazdi AK, Zhang J, Zhang Y, Santhakumar V, Edwards 
            AM, Barsyte-Lovejoy D, Schapira M, Brown PJ, Halabelian L, 
            Arrowsmith CH
  TITLE     A Target Class Ligandability Evaluation of WD40 Repeat-Containing 
            Proteins.
  JOURNAL   J Med Chem. 2025 Jan 23;68(2):1092-1112. doi: 
            10.1021/acs.jmedchem.4c02010. Epub 2024 Nov 4.
  PUBMED    39495097
REFERENCE   2  (bases 1 to 999)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1021/acs.jmedchem.4c02010"; journalName: "J Med Chem"; date: 
            "2025-01-23- 23"; volume: "68"; issue: "2"; pages: "1092-1112"
COMMENT     Sequence Label: pNICBio2_WDR5:2-334
FEATURES             Location/Qualifiers
     source          1..999
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 gcgacggagg agaagaagcc cgagaccgag gccgccagag cacagccaac cccttcgtca
       61 tccgccactc agagcaagcc tacacctgtg aagccaaact atgctctaaa gttcaccctt
      121 gctggccaca ccaaagcagt gtcctccgtg aaattcagcc cgaatggaga gtggctggca
      181 agttcatctg ctgataaact tattaaaatt tggggcgcgt atgatgggaa atttgagaaa
      241 accatatctg gtcacaagct gggaatatcc gatgtagcct ggtcgtcaga ttctaacctt
      301 cttgtttctg cctcagatga caaaaccttg aagatatggg acgtgagctc gggcaagtgt
      361 ctgaaaaccc tgaagggaca cagtaattat gtcttttgct gcaacttcaa tccccagtcc
      421 aaccttattg tctcaggatc ctttgacgaa agcgtgagga tatgggatgt gaaaacaggg
      481 aagtgcctca agactttgcc agctcactcg gatccagtct cggccgttca ttttaatcgt
      541 gatggatcct tgatagtttc aagtagctat gatggtctct gtcgcatctg ggacaccgcc
      601 tcgggccagt gcctgaagac gctcatcgat gacgacaacc cccccgtgtc ttttgtgaag
      661 ttctccccga acggcaaata catcctggcc gccacgctgg acaacactct gaagctctgg
      721 gactacagca aggggaagtg cctgaagacg tacactggcc acaagaatga gaaatactgc
      781 atatttgcca atttctctgt tactggtggg aagtggattg tgtctggctc agaggataac
      841 cttgtttaca tctggaacct tcagacgaaa gagattgtac agaaactaca aggccacaca
      901 gatgtcgtga tctcaacagc ttgtcaccca acagaaaaca tcatcgcctc tgctgcgcta
      961 gaaaatgaca aaacaattaa actgtggaag agtgactgc
//
