LOCUS       sequence-411608-        2190 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Mammalian expression of full-length human DTL. C-terminal NanoLuc 
            luciferase tag..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2190)
  AUTHORS   Ackloo S, Li F, Szewczyk M, Seitova A, Loppnau P, Zeng H, Xu J, 
            Ahmad S, Arnautova YA, Baghaie AJ, Beldar S, Bolotokova A, Centrella
            PA, Chau I, Clark MA, Cuozzo JW, Dehghani-Tafti S, Disch JS, Dong A,
            Dumas A, Feng JA, Ghiabi P, Gibson E, Gilmer J, Goldman B, Green SR,
            Guie MA, Guilinger JP, Harms N, Herasymenko O, Houliston S, 
            Hutchinson A, Kearnes S, Keefe AD, Kimani SW, Kramer T, Kutera M, 
            Kwak HA, Lento C, Li Y, Liu J, Loup J, Machado RAC, Mulhern CJ, 
            Perveen S, Righetto GL, Riley P, Shrestha S, Sigel EA, Silva M, 
            Sintchak MD, Slakman BL, Taylor RD, Thompson J, Torng W, 
            Underkoffler C, von Rechenberg M, Walsh RT, Watson I, Wilson DJ, 
            Wolf E, Yadav M, Yazdi AK, Zhang J, Zhang Y, Santhakumar V, Edwards 
            AM, Barsyte-Lovejoy D, Schapira M, Brown PJ, Halabelian L, 
            Arrowsmith CH
  TITLE     A Target Class Ligandability Evaluation of WD40 Repeat-Containing 
            Proteins.
  JOURNAL   J Med Chem. 2025 Jan 23;68(2):1092-1112. doi: 
            10.1021/acs.jmedchem.4c02010. Epub 2024 Nov 4.
  PUBMED    39495097
REFERENCE   2  (bases 1 to 2190)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1021/acs.jmedchem.4c02010"; journalName: "J Med Chem"; date: 
            "2025-01-23- 23"; volume: "68"; issue: "2"; pages: "1092-1112"
COMMENT     Sequence Label: pNLF1-C_DTL:1-730
FEATURES             Location/Qualifiers
     source          1..2190
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgctcttca attcggtgct ccgccagccc cagcttggcg tcctgagaaa tggatggtct
       61 tcacaatacc ctcttcaatc ccttctgact ggttatcagt gcagtggtaa tgatgaacac
      121 acttcttatg gagaaacagg agtcccagtt cctccttttg gatgtacctt ctcttctgct
      181 cccaatatgg aacatgtact agcagttgcc aatgaagaag gctttgttcg attgtataac
      241 acagaatcac aaagtttcag aaagaagtgc ttcaaagaat ggatggctca ctggaatgcc
      301 gtctttgacc tggcctgggt tcctggtgaa cttaaacttg ttacagcagc aggtgatcaa
      361 acagccaaat tttgggacgt aaaagctggt gagctgattg gaacatgcaa aggtcatcaa
      421 tgcagcctca agtcagttgc cttttctaag tttgagaaag ctgtattctg tacgggtgga
      481 agagatggca acattatggt ctgggatacc aggtgcaaca aaaaagatgg gttttatagg
      541 caagtgaatc aaatcagtgg agctcacaat acctcagaca agcaaacccc ttcaaaaccc
      601 aagaagaaac agaattcaaa aggacttgct ccttctgtgg atttccagca aagtgttact
      661 gtggtcctct ttcaagacga gaatacctta gtctcagcag gagctgtgga tgggataatc
      721 aaagtatggg atttacgtaa gaattatact gcttatcgac aagaacccat agcatccaag
      781 tctttcctgt acccaggtag cagcactcga aaacttggat attcaagtct gattttggat
      841 tccactggct ctactttatt tgctaattgc acagacgata acatctacat gtttaatatg
      901 actgggttga agacttctcc agtggctatt ttcaatggac accagaactc taccttttat
      961 gtaaaatcca gccttagtcc agatgaccag tttttagtca gtggctcaag tgatgaagct
     1021 gcctacatat ggaaggtctc cacaccctgg caacctccta ctgtgctcct gggtcattct
     1081 caagaggtca cgtctgtgtg ctggtgtcca tctgacttca caaagattgc tacctgttct
     1141 gatgacaata cactaaaaat ctggcgcttg aatagaggct tagaggagaa accaggaggt
     1201 gataaacttt ccacggtggg ttgggcctct cagaagaaaa aagagtcaag acctggccta
     1261 gtaacagtaa cgagtagcca gagtactcct gccaaagccc ccagggcaaa gtgcaatcca
     1321 tccaattctt ccccgtcatc cgcagcttgt gccccaagct gtgctggaga cctccctctt
     1381 ccttcaaata ctcctacgtt ctctattaaa acctctcctg ccaaggcccg gtctcccatc
     1441 aacagaagag gctctgtctc ctccgtctct cccaagccac cttcatcttt caagatgtcg
     1501 attagaaact gggtgacccg aacaccttcc tcatcaccac ccatcactcc acctgcttcg
     1561 gagaccaaga tcatgtctcc gagaaaagcc cttattcctg tgagccagaa gtcatcccaa
     1621 gcagaggctt gctctgagtc tagaaataga gtaaagagga ggctagactc aagctgtctg
     1681 gagagtgtga aacaaaagtg tgtgaagagt tgtaactgtg tgactgagct tgatggccaa
     1741 gttgaaaatc ttcatttgga tctgtgctgc cttgctggta accaggaaga ccttagtaag
     1801 gactctctag gtcctaccaa atcaagcaaa attgaaggag ctggtaccag tatctcagag
     1861 cctccgtctc ctatcagtcc gtatgcttca gaaagctgtg gaacgctacc tcttcctttg
     1921 agaccttgtg gagaagggtc tgaaatggta ggcaaagaga atagttcccc agagaataaa
     1981 aactggttgt tggccatggc agccaaacgg aaggctgaga atccatctcc acgaagtccg
     2041 tcatcccaga cacccaattc caggagacag agcggaaaga aattgccaag cccggtcacc
     2101 atcacgccca gctccatgag gaaaatctgc acatacttcc atagaaagtc ccaggaggac
     2161 ttctgtggtc ctgaacactc aacagagtta
//
