LOCUS       sequence-411626-        1998 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Mammalian expression of full-length human LEO1. N-terminal HaloTag..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1998)
  AUTHORS   Ackloo S, Li F, Szewczyk M, Seitova A, Loppnau P, Zeng H, Xu J, 
            Ahmad S, Arnautova YA, Baghaie AJ, Beldar S, Bolotokova A, Centrella
            PA, Chau I, Clark MA, Cuozzo JW, Dehghani-Tafti S, Disch JS, Dong A,
            Dumas A, Feng JA, Ghiabi P, Gibson E, Gilmer J, Goldman B, Green SR,
            Guie MA, Guilinger JP, Harms N, Herasymenko O, Houliston S, 
            Hutchinson A, Kearnes S, Keefe AD, Kimani SW, Kramer T, Kutera M, 
            Kwak HA, Lento C, Li Y, Liu J, Loup J, Machado RAC, Mulhern CJ, 
            Perveen S, Righetto GL, Riley P, Shrestha S, Sigel EA, Silva M, 
            Sintchak MD, Slakman BL, Taylor RD, Thompson J, Torng W, 
            Underkoffler C, von Rechenberg M, Walsh RT, Watson I, Wilson DJ, 
            Wolf E, Yadav M, Yazdi AK, Zhang J, Zhang Y, Santhakumar V, Edwards 
            AM, Barsyte-Lovejoy D, Schapira M, Brown PJ, Halabelian L, 
            Arrowsmith CH
  TITLE     A Target Class Ligandability Evaluation of WD40 Repeat-Containing 
            Proteins.
  JOURNAL   J Med Chem. 2025 Jan 23;68(2):1092-1112. doi: 
            10.1021/acs.jmedchem.4c02010. Epub 2024 Nov 4.
  PUBMED    39495097
REFERENCE   2  (bases 1 to 1998)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1021/acs.jmedchem.4c02010"; journalName: "J Med Chem"; date: 
            "2025-01-23- 23"; volume: "68"; issue: "2"; pages: "1092-1112"
COMMENT     Sequence Label: pHTN-HaloTag_LEO1:1-666
FEATURES             Location/Qualifiers
     source          1..1998
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggcggata tggaggatct cttcgggagc gacgccgaca gcgaagctga gcgtaaagat
       61 tctgattctg gatctgactc agattctgat caagagaatg ctgcctctgg cagtaatgcc
      121 tctggaagtg aaagtgatca ggatgaaaga ggtgattcag gacaaccaag taataaggaa
      181 ctgtttggag atgacagtga ggacgaggga gcttcacatc atagtggtag tgataatcac
      241 tctgaaagat cagacaatag atcagaagct tctgagcgtt ctgaccatga ggacaatgac
      301 ccctcagatg tagatcagca cagtggatca gaagccccta atgatgatga agacgaaggt
      361 catagatcgg atggagggag ccatcattca gaagcagaag gttctgaaaa agcacattca
      421 gatgatgaaa aatggggcag agaagataaa agtgaccagt cagatgatga aaagatacaa
      481 aattctgatg atgaggagag ggcacaagga tctgatgaag ataagctgca gaattctgac
      541 gatgatgaga aaatgcagaa cacagatgat gaggagaggc ctcagctttc cgatgatgag
      601 agacaacagc tatctgagga ggaaaaggct aattctgatg atgaacggcc ggtagcttct
      661 gataatgatg atgagaaaca gaattctgat gatgaagaac aaccacagct gtctgatgaa
      721 gagaaaatgc aaaattctga tgatgaaagg ccacaggcct cagatgaaga acacaggcat
      781 tcagatgatg aagaggaaca ggatcataaa tcagaatctg caagaggcag tgatagtgaa
      841 gatgaagttt tacgaatgaa acgcaagaat gcgattgcat ctgattcaga agcggatagt
      901 gacactgagg tgccaaaaga taatagtgga accatggatt tatttggagg tgcagatgat
      961 atctcttcag ggagtgatgg agaagacaaa ccacctactc caggacagcc tgttgatgaa
     1021 aatggattgc ctcaggatca acaggaagag gagccaattc ctgagaccag aatagaagta
     1081 gaaataccca aagtaaacac tgatttagga aacgacttat attttgttaa actgcccaac
     1141 tttctcagtg tagagcccag accttttgat cctcagtatt atgaagatga atttgaagat
     1201 gaagaaatgc tggatgaaga aggtagaacc aggttaaaat taaaggtaga aaatactata
     1261 agatggagga tacgccgaga tgaagaagga aatgaaatta aagaaagcaa tgctcggata
     1321 gtcaagtggt cagatggaag catgtccctg catttaggca atgaagtgtt tgatgtgtac
     1381 aaagccccac tgcagggcga ccacaatcat ctttttataa gacaaggtac tggtctacag
     1441 ggacaagcag tctttaaaac gaaactcacc ttcagacctc actctacgga cagtgccaca
     1501 catagaaaga tgactctgtc acttgcagat aggtgttcaa agacacagaa gattagaatc
     1561 ttgccaatgg ctggtcgtga tcctgaatgc caacgcacag aaatgattaa gaaagaagaa
     1621 gaacgtttga gggcttccat acgtagggaa tctcagcagc gccgaatgag agagaaacag
     1681 caccagcggg ggctgagcgc cagttacctg gaacctgatc gatacgatga ggaggaggaa
     1741 ggcgaggagt ccatcagctt ggctgccatt aaaaaccgat ataaaggggg cattcgagag
     1801 gaacgagcca gaatctattc atcagacagt gatgagggat cagaagaaga taaagctcaa
     1861 agattactca aagcaaagaa acttaccagt gatgaggaag gtgaaccttc cggaaagaga
     1921 aaagcagaag atgatgataa agcaaataaa aagcataaga agtatgtgat cagcgatgaa
     1981 gaggaagaag atgatgat
//
