LOCUS       sequence-411656-        3213 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Mammalian expression of full-length human XPO1. C-terminal NanoLuc 
            luciferase tag..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 3213)
  AUTHORS   Ackloo S, Li F, Szewczyk M, Seitova A, Loppnau P, Zeng H, Xu J, 
            Ahmad S, Arnautova YA, Baghaie AJ, Beldar S, Bolotokova A, Centrella
            PA, Chau I, Clark MA, Cuozzo JW, Dehghani-Tafti S, Disch JS, Dong A,
            Dumas A, Feng JA, Ghiabi P, Gibson E, Gilmer J, Goldman B, Green SR,
            Guie MA, Guilinger JP, Harms N, Herasymenko O, Houliston S, 
            Hutchinson A, Kearnes S, Keefe AD, Kimani SW, Kramer T, Kutera M, 
            Kwak HA, Lento C, Li Y, Liu J, Loup J, Machado RAC, Mulhern CJ, 
            Perveen S, Righetto GL, Riley P, Shrestha S, Sigel EA, Silva M, 
            Sintchak MD, Slakman BL, Taylor RD, Thompson J, Torng W, 
            Underkoffler C, von Rechenberg M, Walsh RT, Watson I, Wilson DJ, 
            Wolf E, Yadav M, Yazdi AK, Zhang J, Zhang Y, Santhakumar V, Edwards 
            AM, Barsyte-Lovejoy D, Schapira M, Brown PJ, Halabelian L, 
            Arrowsmith CH
  TITLE     A Target Class Ligandability Evaluation of WD40 Repeat-Containing 
            Proteins.
  JOURNAL   J Med Chem. 2025 Jan 23;68(2):1092-1112. doi: 
            10.1021/acs.jmedchem.4c02010. Epub 2024 Nov 4.
  PUBMED    39495097
REFERENCE   2  (bases 1 to 3213)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1021/acs.jmedchem.4c02010"; journalName: "J Med Chem"; date: 
            "2025-01-23- 23"; volume: "68"; issue: "2"; pages: "1092-1112"
COMMENT     Sequence Label: pNLF1-C_XPO1:1-1071
FEATURES             Location/Qualifiers
     source          1..3213
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgccagcaa ttatgacaat gttagcagac catgcagctc gtcagctgct tgatttcagc
       61 caaaaactgg atatcaactt attagataat gtggtgaatt gcttatacca tggagaagga
      121 gcccagcaaa gaatggctca agaagtactg acacatttaa aggagcatcc tgatgcttgg
      181 acaagagtcg acacaatttt ggaattttct cagaatatga atacgaaata ctatggacta
      241 caaattttgg aaaatgtgat aaaaacaagg tggaagattc ttccaaggaa ccagtgcgaa
      301 ggaataaaaa aatacgttgt tggcctcatt atcaagacgt catctgaccc aacttgtgta
      361 gagaaagaaa aggtgtatat cggaaaatta aatatgatcc ttgttcagat actgaaacaa
      421 gaatggccca aacattggcc aacttttatc agtgatattg ttggagcaag taggaccagc
      481 gaaagtctct gtcaaaataa tatggtgatt cttaaactct tgagtgaaga agtatttgat
      541 ttctctagtg gacagataac ccaagtcaaa tctaagcatt taaaagacag catgtgcaat
      601 gaattctcac agatatttca actgtgtcag tttgtaatgg aaaattctca aaatgctcca
      661 cttgtacatg caaccttgga aacattgctc agatttctga actggattcc cctgggatat
      721 atttttgaga ccaaattaat cagcacattg atttataagt tcctgaatgt tccaatgttt
      781 cgaaatgtct ctctgaagtg cctcactgag attgctggtg tgagtgtaag ccaatatgaa
      841 gaacaatttg taacactatt tactctgaca atgatgcaac taaagcagat gcttccttta
      901 aataccaata ttcgacttgc gtactcaaat ggaaaagatg atgaacagaa cttcattcaa
      961 aatctcagtt tgtttctctg cacctttctt aaggaacatg atcaacttat agaaaaaaga
     1021 ttaaatctca gggaaactct tatggaggcc cttcattata tgttgttggt atctgaagta
     1081 gaagaaactg aaatctttaa aatttgtctt gaatactgga atcatttggc tgctgaactc
     1141 tatagagaga gtccattctc tacatctgcc tctccgttgc tttctggaag tcaacatttt
     1201 gatgttcctc ccaggagaca gctatatttg cccatgttat tcaaggtccg tttattaatg
     1261 gttagtcgaa tggctaaacc agaggaagta ttggttgtag agaatgatca aggagaagtt
     1321 gtgagagaat tcatgaagga tacagattcc ataaatttgt ataagaatat gagggaaaca
     1381 ttggtttatc ttactcatct ggattatgta gatacagaaa gaataatgac agagaagctt
     1441 cacaatcaag tgaatggtac agagtggtca tggaaaaatt tgaatacatt gtgttgggca
     1501 ataggctcca ttagtggagc aatgcatgaa gaggacgaaa aacgatttct tgttactgtt
     1561 ataaaggatc tattaggatt atgtgaacag aaaagaggca aagataataa agctattatt
     1621 gcatcaaata tcatgtacat agtaggtcaa tacccacgtt ttttgagagc tcactggaaa
     1681 tttctgaaga ctgtagttaa caagctgttc gaattcatgc atgagaccca tgatggagtc
     1741 caggatatgg cttgtgatac tttcattaaa atagcccaaa aatgccgcag gcatttcgtt
     1801 caggttcagg ttggagaagt gatgccattt attgatgaaa ttttgaacaa cattaacact
     1861 attatttgtg atcttcagcc tcaacaggtt catacgtttt atgaagctgt ggggtacatg
     1921 attggtgcac aaacagatca aacagtacaa gaacacttga tagaaaagta catgttactc
     1981 cctaatcaag tgtgggatag tataatccag caggcaacca aaaatgtgga tatactgaaa
     2041 gatcctgaaa cagtcaagca gcttggtagc attttgaaaa caaatgtgag agcctgcaaa
     2101 gctgttggac acccctttgt aattcagctt ggaagaattt atttagatat gcttaatgta
     2161 tacaagtgcc tcagtgaaaa tatttctgca gctatccaag ctaatggtga aatggttaca
     2221 aagcaaccat tgattagaag tatgcgaact gtaaaaaggg aaactttaaa gttaatatct
     2281 ggttgggtga gccgatccaa tgatccacag atggtcgctg aaaattttgt tccccctctg
     2341 ttggatgcag ttctcattga ttatcagaga aatgtcccag ctgctagaga accagaagtg
     2401 cttagtacta tggccataat tgtcaacaag ttagggggac atataacagc tgaaatacct
     2461 caaatatttg atgctgtttt tgaatgcaca ttgaatatga taaataagga ctttgaagaa
     2521 tatcctgaac atagaacgaa ctttttctta ctacttcagg ctgtcaattc tcattgtttc
     2581 ccagcattcc ttgctattcc acctacacag tttaaacttg ttttggattc catcatttgg
     2641 gctttcaaac atactatgag gaatgtcgca gatacgggct tacagatact ttttacactc
     2701 ttacaaaatg ttgcacaaga agaagctgca gctcagagtt tttatcaaac ttatttttgt
     2761 gatattctcc agcatatctt ttctgttgtg acagacactt cacatactgc tggtttaaca
     2821 atgcatgcat caattcttgc atatatgttt aatttggttg aagaaggaaa aataagtaca
     2881 tcattaaatc ctggaaatcc agttaacaac caaatctttc ttcaggaata tgtggctaat
     2941 ctccttaagt cggccttccc tcacctacaa gatgctcaag taaagctctt tgtgacaggg
     3001 cttttcagct taaatcaaga tattcctgct ttcaaggaac atttaagaga tttcctagtt
     3061 caaataaagg aatttgcagg tgaagacact tctgatttgt ttttggaaga gagagaaata
     3121 gccctacggc aggctgatga agagaaacat aaacgtcaaa tgtctgtccc tggcatcttt
     3181 aatccacatg agattccaga agaaatgtgt gat
//
