LOCUS       sequence-411658-        3873 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Mammalian expression of full-length human PLCG1 isoform 2. 
            C-terminal NanoLuc luciferase tag..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 3873)
  AUTHORS   Ackloo S, Li F, Szewczyk M, Seitova A, Loppnau P, Zeng H, Xu J, 
            Ahmad S, Arnautova YA, Baghaie AJ, Beldar S, Bolotokova A, Centrella
            PA, Chau I, Clark MA, Cuozzo JW, Dehghani-Tafti S, Disch JS, Dong A,
            Dumas A, Feng JA, Ghiabi P, Gibson E, Gilmer J, Goldman B, Green SR,
            Guie MA, Guilinger JP, Harms N, Herasymenko O, Houliston S, 
            Hutchinson A, Kearnes S, Keefe AD, Kimani SW, Kramer T, Kutera M, 
            Kwak HA, Lento C, Li Y, Liu J, Loup J, Machado RAC, Mulhern CJ, 
            Perveen S, Righetto GL, Riley P, Shrestha S, Sigel EA, Silva M, 
            Sintchak MD, Slakman BL, Taylor RD, Thompson J, Torng W, 
            Underkoffler C, von Rechenberg M, Walsh RT, Watson I, Wilson DJ, 
            Wolf E, Yadav M, Yazdi AK, Zhang J, Zhang Y, Santhakumar V, Edwards 
            AM, Barsyte-Lovejoy D, Schapira M, Brown PJ, Halabelian L, 
            Arrowsmith CH
  TITLE     A Target Class Ligandability Evaluation of WD40 Repeat-Containing 
            Proteins.
  JOURNAL   J Med Chem. 2025 Jan 23;68(2):1092-1112. doi: 
            10.1021/acs.jmedchem.4c02010. Epub 2024 Nov 4.
  PUBMED    39495097
REFERENCE   2  (bases 1 to 3873)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1021/acs.jmedchem.4c02010"; journalName: "J Med Chem"; date: 
            "2025-01-23- 23"; volume: "68"; issue: "2"; pages: "1092-1112"
COMMENT     Sequence Label: pNLF1-C_PLCG1:1-1291
FEATURES             Location/Qualifiers
     source          1..3873
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggcgggcg ccgcgtcccc ttgcgccaac ggctgcgggc ccggcgcgcc ctcggacgcc
       61 gaggtgctgc acctctgccg cagcctcgag gtgggcaccg tcatgacttt gttctactcc
      121 aagaagtcgc agcgacccga gcggaagacc ttccaggtca agctggagac gcgccagatc
      181 acgtggagcc ggggcgccga caagatcgag ggggccattg acattcgtga aattaaggag
      241 atccgcccag ggaagacctc acgggacttt gatcgctatc aagaggaccc agctttccgg
      301 ccggaccagt cacattgctt tgtcattctc tatggaatgg aatttcgcct gaaaacgctg
      361 agcctgcaag ccacatctga ggatgaagtg aacatgtgga tcaagggctt aacttggctg
      421 atggaggata cattgcaggc acccacaccc ctgcagattg agaggtggct ccggaagcag
      481 ttttactcag tggatcggaa tcgtgaggat cgtatatcag ccaaggacct gaagaacatg
      541 ctgtcccagg tcaactaccg ggtccccaac atgcgcttcc tccgagagcg gctgacggac
      601 ctggagcagc gcagcgggga catcacctac gggcagtttg ctcagctgta ccgcagcctc
      661 atgtacagcg cccagaagac gatggacctc cccttcttgg aagccagtac tctgagggct
      721 ggggagcggc cggagctttg ccgagtgtcc cttcctgagt tccagcagtt ccttcttgac
      781 taccaggggg agctgtgggc tgttgatcgc ctccaggtgc aggagttcat gctcagcttc
      841 ctccgagacc ccttacgaga gatcgaggag ccatacttct tcctggatga gtttgtcacc
      901 ttcctgttct ccaaagagaa cagtgtgtgg aactcgcagc tggatgcagt atgcccggac
      961 accatgaaca accctctttc ccactactgg atctcctcct cgcacaacac gtacctgacc
     1021 ggggaccagt tctccagtga gtcctccttg gaagcctatg ctcgctgcct gcggatgggc
     1081 tgtcgctgca ttgagttgga ctgctgggac ggcccggatg ggatgccagt tatttaccat
     1141 gggcacaccc ttaccaccaa gatcaagttc tcagatgtcc tgcacaccat caaggagcat
     1201 gcctttgtgg cctcagagta cccagtcatc ctgtccattg aggaccactg cagcattgcc
     1261 cagcagagaa acatggccca atacttcaag aaggtgctgg gggacacact cctcaccaag
     1321 cccgtggaga tctctgccga cgggctcccc tcacccaacc agcttaagag gaagatcctc
     1381 atcaagcaca agaagctggc tgagggcagt gcctacgagg aggtgcctac atccatgatg
     1441 tactctgaga acgacatcag caactctatc aagaatggca tcctctacct ggaggaccct
     1501 gtgaaccacg aatggtatcc ccactacttt gttctgacca gcagcaagat ctactactct
     1561 gaggagacca gcagtgacca gggcaacgag gatgaggagg agcccaagga ggtcagcagc
     1621 agcacagagc tgcactccaa tgagaagtgg ttccatggga agctaggggc agggcgtgac
     1681 gggcgtcaca tcgctgagcg cctgcttact gagtactgca tcgagaccgg agcccctgac
     1741 ggctccttcc tcgtgcgaga gagtgagacc ttcgtgggcg actacacgct ctctttctgg
     1801 cggaacggga aagtccagca ctgccgtatc cactcccggc aagatgctgg gacccccaag
     1861 ttcttcttga cagacaacct cgtctttgac tccctctatg acctcatcac gcactaccag
     1921 caggtgcccc tgcgctgtaa tgagtttgag atgcgacttt cagagcctgt cccacagacc
     1981 aacgcccacg agagcaaaga gtggtaccac gcgagcctga ccagagcaca ggctgagcac
     2041 atgctaatgc gcgtccctcg tgatggggcc ttcctggtgc ggaagcggaa tgaacccaac
     2101 tcatatgcca tctctttccg ggctgagggc aagatcaagc attgccgtgt ccagcaagag
     2161 ggccagacag tgatgctagg gaactcggag ttcgacagcc ttgttgacct catcagctac
     2221 tatgagaaac acccgctata ccgcaagatg aagctgcgct atcccatcaa cgaggaggca
     2281 ctggagaaga ttggcacagc tgagcctgac tacggggccc tgtatgaggg acgcaaccct
     2341 ggcttctatg tagaggcaaa ccctatgcca actttcaagt gtgcagtcaa agccctcttt
     2401 gactacaagg cccagaggga ggacgagctg accttcacca agagcgccat catccagaat
     2461 gtggagaagc aagagggagg ctggtggcga ggggactacg gagggaagaa gcagctgtgg
     2521 ttcccatcaa actacgtgga agagatggtc aaccccgtgg ccctggagcc ggagagggag
     2581 cacttggacg agaacagccc cctaggggac ttgctgcggg gggtcttgga tgtgccggct
     2641 tgtcagattg ccatccgtcc tgagggcaag aacaaccggc tcttcgtctt ctccatcagc
     2701 atggcgtcgg tggcccactg gtccctggat gttgctgccg actcacagga ggagctgcag
     2761 gactgggtga aaaagatccg tgaagtggcc cagacagcag acgccaggct cactgaaggg
     2821 aagataatgg aacggaggaa gaagattgcc ctggagctct ctgaacttgt cgtctactgc
     2881 cggcctgttc cctttgatga agagaagatt ggcacagaac gtgcttgcta ccgggacatg
     2941 tcatccttcc cggaaaccaa ggctgagaaa tacgtgaaca aggccaaagg caagaagttc
     3001 cttcagtaca atcgactgca gctctcccgc atctacccca agggccagcg actggattcc
     3061 tccaactacg atcctttgcc catgtggatc tgtggcagtc agcttgtggc cctcaacttc
     3121 cagacccctg acaagcctat gcagatgaac caggccctct tcatgacggg caggcactgt
     3181 ggctacgtgc tgcagccaag caccatgcgg gatgaggcct tcgacccctt tgacaagagc
     3241 agcctccgcg ggctggagcc atgtgccatc tctattgagg tgctgggggc ccgacatctg
     3301 ccaaagaatg gccgaggcat tgtgtgtcct tttgtggaga ttgaggtggc tggagctgag
     3361 tatgacagca ccaagcagaa gacagagttt gtggtggaca atggactcaa ccctgtatgg
     3421 ccagccaagc ccttccactt ccagatcagt aaccctgaat ttgcctttct gcgcttcgtg
     3481 gtgtatgagg aagacatgtt tagtgaccag aatttcctgg ctcaggctac tttcccagta
     3541 aaaggcctga agacaggata cagagcagtg cctttgaaga acaactacag tgaggacctg
     3601 gagttggcct ccctgctgat caagattgac attttccctg ccaagcagga gaatggtgac
     3661 ctcagtccct tcagtggtac gtccctgcgg gagcggggct cagatgcctc aggccagctg
     3721 tttcatggcc gagcccggga aggctccttt gaatcccgct accagcagcc gtttgaggac
     3781 ttccgcatct cccaggagca tctcgcagac cattttgaca gtcgagaacg aagggcccca
     3841 agaaggactc gggtcaatgg agacaaccgc ctc
//
