LOCUS       sequence-411668-        1635 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Mammalian expression of full-length human AIRE. C-terminal NanoLuc 
            luciferase tag..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1635)
  AUTHORS   Ackloo S, Li F, Szewczyk M, Seitova A, Loppnau P, Zeng H, Xu J, 
            Ahmad S, Arnautova YA, Baghaie AJ, Beldar S, Bolotokova A, Centrella
            PA, Chau I, Clark MA, Cuozzo JW, Dehghani-Tafti S, Disch JS, Dong A,
            Dumas A, Feng JA, Ghiabi P, Gibson E, Gilmer J, Goldman B, Green SR,
            Guie MA, Guilinger JP, Harms N, Herasymenko O, Houliston S, 
            Hutchinson A, Kearnes S, Keefe AD, Kimani SW, Kramer T, Kutera M, 
            Kwak HA, Lento C, Li Y, Liu J, Loup J, Machado RAC, Mulhern CJ, 
            Perveen S, Righetto GL, Riley P, Shrestha S, Sigel EA, Silva M, 
            Sintchak MD, Slakman BL, Taylor RD, Thompson J, Torng W, 
            Underkoffler C, von Rechenberg M, Walsh RT, Watson I, Wilson DJ, 
            Wolf E, Yadav M, Yazdi AK, Zhang J, Zhang Y, Santhakumar V, Edwards 
            AM, Barsyte-Lovejoy D, Schapira M, Brown PJ, Halabelian L, 
            Arrowsmith CH
  TITLE     A Target Class Ligandability Evaluation of WD40 Repeat-Containing 
            Proteins.
  JOURNAL   J Med Chem. 2025 Jan 23;68(2):1092-1112. doi: 
            10.1021/acs.jmedchem.4c02010. Epub 2024 Nov 4.
  PUBMED    39495097
REFERENCE   2  (bases 1 to 1635)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1021/acs.jmedchem.4c02010"; journalName: "J Med Chem"; date: 
            "2025-01-23- 23"; volume: "68"; issue: "2"; pages: "1092-1112"
COMMENT     Sequence Label: pNLF1-C_AIRE:1-545
FEATURES             Location/Qualifiers
     source          1..1635
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggcgacgg acgcggcgct acgccggctt ctgaggctgc accgcacgga gatcgcggtg
       61 gccgtggaca gcgccttccc actgctgcac gcgctggctg accacgacgt ggtccccgag
      121 gacaagtttc aggagacgct tcatctgaag gaaaaggagg gctgccccca ggccttccac
      181 gccctcctgt cctggctgct gacccaggac tccacagcca tcctggactt ctggagggtg
      241 ctgttcaagg actacaacct ggagcgctat ggccggctgc agcccatcct ggacagcttc
      301 cccaaagatg tggacctcag ccagccccgg aaggggagga agcccccggc cgtccccaag
      361 gctttggtac cgccacccag actccccacc aagaggaagg cctcagaaga ggctcgagct
      421 gccgcgccag cagccctgac tccaaggggc accgccagcc caggctctca actgaaggcc
      481 aagcccccca agaagccgga gagcagcgca gagcagcagc gccttccact cgggaacggg
      541 attcagacca tgtcagcttc agtccagaga gctgtggcca tgtcctccgg ggacgtcccg
      601 ggagcccgag gggccgtgga ggggatcctc atccagcagg tgtttgagtc aggcggctcc
      661 aagaagtgca tccaggttgg tggggagttc tacactccca gcaagttcga agactccggc
      721 agtgggaaga acaaggcccg cagcagcagt ggcccgaagc ctctggttcg agccaaggga
      781 gcccagggcg ctgcccccgg tggaggtgag gctaggctgg gccagcaggg cagcgttccc
      841 gcccctctgg ccctccccag tgacccccag ctccaccaga agaatgagga cgagtgtgcc
      901 gtgtgtcggg acggcgggga gctcatctgc tgtgacggct gccctcgggc cttccacctg
      961 gcctgcctgt cccctccgct ccgggagatc cccagtggga cctggaggtg ctccagctgc
     1021 ctgcaggcaa cagtccagga ggtgcagccc cgggcagagg agccccggcc ccaggagcca
     1081 cccgtggaga ccccgctccc cccggggctt aggtcggcgg gagaggaggt aagaggtcca
     1141 cctggggaac ccctagccgg catggacacg actcttgtct acaagcacct gccggctccg
     1201 ccttctgcag ccccgctgcc agggctggac tcctcggccc tgcaccccct actgtgtgtg
     1261 ggtcctgagg gtcagcagaa cctggctcct ggtgcgcgtt gcggggtgtg cggagatggt
     1321 acggacgtgc tgcggtgtac tcactgcgcc gctgccttcc actggcgctg ccacttccca
     1381 gccggcacct cccggcccgg gacgggcctg cgctgcagat cctgctcagg agacgtgacc
     1441 ccagcccctg tggagggggt gctggccccc agccccgccc gcctggcccc tgggcctgcc
     1501 aaggatgaca ctgccagtca cgagcccgct ctgcacaggg atgacctgga gtcccttctg
     1561 agcgagcaca ccttcgatgg catcctgcag tgggccatcc agagcatggc ccgtccggcg
     1621 gcccccttcc cctcc
//
