LOCUS       sequence-411864-        3588 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Mammalian expression of full-length human AHI1. N-terminal HiBiT 
            tag..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 3588)
  AUTHORS   Ackloo S, Li F, Szewczyk M, Seitova A, Loppnau P, Zeng H, Xu J, 
            Ahmad S, Arnautova YA, Baghaie AJ, Beldar S, Bolotokova A, Centrella
            PA, Chau I, Clark MA, Cuozzo JW, Dehghani-Tafti S, Disch JS, Dong A,
            Dumas A, Feng JA, Ghiabi P, Gibson E, Gilmer J, Goldman B, Green SR,
            Guie MA, Guilinger JP, Harms N, Herasymenko O, Houliston S, 
            Hutchinson A, Kearnes S, Keefe AD, Kimani SW, Kramer T, Kutera M, 
            Kwak HA, Lento C, Li Y, Liu J, Loup J, Machado RAC, Mulhern CJ, 
            Perveen S, Righetto GL, Riley P, Shrestha S, Sigel EA, Silva M, 
            Sintchak MD, Slakman BL, Taylor RD, Thompson J, Torng W, 
            Underkoffler C, von Rechenberg M, Walsh RT, Watson I, Wilson DJ, 
            Wolf E, Yadav M, Yazdi AK, Zhang J, Zhang Y, Santhakumar V, Edwards 
            AM, Barsyte-Lovejoy D, Schapira M, Brown PJ, Halabelian L, 
            Arrowsmith CH
  TITLE     A Target Class Ligandability Evaluation of WD40 Repeat-Containing 
            Proteins.
  JOURNAL   J Med Chem. 2025 Jan 23;68(2):1092-1112. doi: 
            10.1021/acs.jmedchem.4c02010. Epub 2024 Nov 4.
  PUBMED    39495097
REFERENCE   2  (bases 1 to 3588)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1021/acs.jmedchem.4c02010"; journalName: "J Med Chem"; date: 
            "2025-01-23- 23"; volume: "68"; issue: "2"; pages: "1092-1112"
COMMENT     Sequence Label: pBiT3.1-N_AHI1:1-1196
FEATURES             Location/Qualifiers
     source          1..3588
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgcctacag ctgagagtga agcaaaagta aaaaccaaag ttcgctttga agaattgctt
       61 aagacccaca gtgatctaat gcgtgaaaag aaaaaactga agaaaaaact tgtcaggtct
      121 gaagaaaaca tctcacctga cactattaga agcaatcttc actatatgaa agaaactaca
      181 agtgatgatc ccgacactat tagaagcaat cttccccata ttaaagaaac tacaagtgat
      241 gatgtaagtg ctgctaacac taacaacctg aagaagagca cgagagtcac taaaaacaaa
      301 ttgaggaaca cacagttagc aactgaaaat cctaatggtg atgctagtgt agaggaagac
      361 aaacaaggaa agccaaataa aaaggtgata aagacggtgc cccagttgac tacacaagac
      421 ctgaaaccgg aaactcctga gaataaggtt gattctacac accagaaaac acatacaaag
      481 ccacagccag gcgttgatca tcagaaaagt gagaaggcaa atgagggaag agaagagact
      541 gatttagaag aggatgaaga attgatgcaa gcatatcagt gccatgtaac tgaagaaatg
      601 gcaaaggaga ttaagaggaa aataagaaag aaactgaaag aacagttgac ttactttccc
      661 tcagatactt tattccatga tgacaaacta agcagtgaaa aaaggaaaaa gaaaaaggaa
      721 gttccagtct tctctaaagc tgaaacaagt acattgacca tctctggtga cacagttgaa
      781 ggtgaacaaa agaaagaatc ttcagttaga tcagtttctt cagattctca tcaagatgat
      841 gaaataagct caatggaaca aagcacagaa gacagcatgc aagatgatac aaaacctaaa
      901 ccaaaaaaaa caaaaaagaa gactaaagca gttgcagata ataatgaaga tgttgatggt
      961 gatggtgttc atgaaataac aagccgagat agcccggttt atcccaaatg tttgcttgat
     1021 gatgaccttg tcttgggagt ttacattcac cgaactgata gacttaagtc agattttatg
     1081 atttctcacc caatggtaaa aattcatgtg gttgatgagc atactggtca atatgtcaag
     1141 aaagatgata gtggacggcc tgtttcatct tactatgaaa aagagaatgt ggattatatt
     1201 cttcctatta tgacccagcc atatgatttt aaacagttaa aatcaagact tccagagtgg
     1261 gaagaacaaa ttgtatttaa tgaaaatttt ccctatttgc ttcgaggctc tgatgagagt
     1321 cctaaagtca tcctgttctt tgagattctt gatttcttaa gcgtggatga aattaagaat
     1381 aattctgagg ttcaaaacca agaatgtggc tttcggaaaa ttgcctgggc atttcttaag
     1441 cttctgggag ccaatggaaa tgcaaacatc aactcaaaac ttcgcttgca gctatattac
     1501 ccacctacta agcctcgatc cccattaagt gttgttgagg catttgaatg gtggtcaaaa
     1561 tgtccaagaa atcattaccc atcaacactg tacgtaactg taagaggact gaaagttcca
     1621 gactgtataa agccatctta ccgctctatg atggctcttc aggaggaaaa aggtaaacca
     1681 gtgcattgtg aacgtcacca tgagtcaagc tcagtagaca cagaacctgg attagaagag
     1741 tcaaaggaag taataaagtg gaaacgactc cctgggcagg cttgccgtat cccaaacaaa
     1801 cacctcttct cactaaatgc aggagaacga ggatgttttt gtcttgattt ctcccacaat
     1861 ggaagaatat tagcagcagc ttgtgccagc cgggatggat atccaattat tttatatgaa
     1921 attccttctg gacgtttcat gagagaattg tgtggccacc tcaatatcat ttatgatctt
     1981 tcctggtcaa aagatgatca ctacatcctt acttcatcat ctgatggcac tgccaggata
     2041 tggaaaaatg aaataaacaa tacaaatact ttcagagttt tacctcatcc ttcttttgtt
     2101 tacacggcta aattccatcc agctgtaaga gagctagtag ttacaggatg ctatgattcc
     2161 atgatacgga tatggaaagt tgagatgaga gaagattctg ccatattggt ccgacagttt
     2221 gatgttcaca aaagttttat caactcactt tgttttgata ctgaaggtca tcatatgtat
     2281 tcaggagatt gtacaggggt gattgttgtt tggaatacct atgtcaagat taatgatttg
     2341 gaacattcag tgcaccactg gactataaat aaggaaatta aagaaactga gtttaaggga
     2401 attccaataa gttatttgga gattcatccc aatggaaaac gtttgttaat ccataccaaa
     2461 gacagtactt tgagaattat ggatctccgg atattagtag caaggaagtt tgtaggagca
     2521 gcaaattatc gggagaagat tcatagtact ttgactccat gtgggacttt tctgtttgct
     2581 ggaagtgagg atggtatagt gtatgtttgg aacccagaaa caggagaaca agtagccatg
     2641 tattctgact tgccattcaa gtcacccatt cgagacattt cttatcatcc atttgaaaat
     2701 atggttgcat tctgtgcatt tgggcaaaat gagccaattc ttctgtatat ttacgatttc
     2761 catgttgccc agcaggaggc tgaaatgttc aaacgctaca atggaacatt tccattacct
     2821 ggaatacacc aaagtcaaga tgccctatgt acctgtccaa aactacccca tcaaggctct
     2881 tttcagattg atgaatttgt ccacactgaa agttcttcaa cgaagatgca gctagtaaaa
     2941 cagaggcttg aaactgtcac agaggtgata cgttcctgtg ctgcaaaagt caacaaaaat
     3001 ctctcattta cttcaccacc agcagtttcc tcacaacagt ctaagttaaa gcagtcaaac
     3061 atgctgaccg ctcaagagat tctacatcag tttggtttca ctcagaccgg gattatcagc
     3121 atagaaagaa agccttgtaa ccatcaggta gatacagcac caacggtagt ggctctttat
     3181 gactacacag cgaatcgatc agatgaacta accatccatc gcggagacat tatccgagtg
     3241 tttttcaaag ataatgaaga ctggtggtat ggcagcatag gaaagggaca ggaaggttat
     3301 tttccagcta atcatgtggc tagtgaaaca ctgtatcaag aactgcctcc tgagataaag
     3361 gagcgatccc ctcctttaag ccctgaggaa aaaactaaaa tagaaaaatc tccagctcct
     3421 caaaagcaat caatcaataa gaacaagtcc caggacttca gactaggctc agaatctatg
     3481 acacattctg aaatgagaaa agaacagagc catgaggacc aaggacacat aatggataca
     3541 cggatgagga agaacaagca agcaggcaga aaagtcactc taatagag
//
