LOCUS       sequence-412040-        3183 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Mammalian expression of full-length human FBXW10 isoform 2. 
            C-terminal HiBiT tag..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 3183)
  AUTHORS   Ackloo S, Li F, Szewczyk M, Seitova A, Loppnau P, Zeng H, Xu J, 
            Ahmad S, Arnautova YA, Baghaie AJ, Beldar S, Bolotokova A, Centrella
            PA, Chau I, Clark MA, Cuozzo JW, Dehghani-Tafti S, Disch JS, Dong A,
            Dumas A, Feng JA, Ghiabi P, Gibson E, Gilmer J, Goldman B, Green SR,
            Guie MA, Guilinger JP, Harms N, Herasymenko O, Houliston S, 
            Hutchinson A, Kearnes S, Keefe AD, Kimani SW, Kramer T, Kutera M, 
            Kwak HA, Lento C, Li Y, Liu J, Loup J, Machado RAC, Mulhern CJ, 
            Perveen S, Righetto GL, Riley P, Shrestha S, Sigel EA, Silva M, 
            Sintchak MD, Slakman BL, Taylor RD, Thompson J, Torng W, 
            Underkoffler C, von Rechenberg M, Walsh RT, Watson I, Wilson DJ, 
            Wolf E, Yadav M, Yazdi AK, Zhang J, Zhang Y, Santhakumar V, Edwards 
            AM, Barsyte-Lovejoy D, Schapira M, Brown PJ, Halabelian L, 
            Arrowsmith CH
  TITLE     A Target Class Ligandability Evaluation of WD40 Repeat-Containing 
            Proteins.
  JOURNAL   J Med Chem. 2025 Jan 23;68(2):1092-1112. doi: 
            10.1021/acs.jmedchem.4c02010. Epub 2024 Nov 4.
  PUBMED    39495097
REFERENCE   2  (bases 1 to 3183)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1021/acs.jmedchem.4c02010"; journalName: "J Med Chem"; date: 
            "2025-01-23- 23"; volume: "68"; issue: "2"; pages: "1092-1112"
COMMENT     Sequence Label: pBiT3.1-C_FBXW10:1-1061
FEATURES             Location/Qualifiers
     source          1..3183
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     regulatory      1012..1021
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
ORIGIN
        1 atggaaaacc tggaatcaag gctcaagaat gccccctatt ttcgttgtga gaagggaacc
       61 gattccatcc ctctatgccg gaagtgtgag acgtgtgtct tagcctggaa gatcttctct
      121 accaaagagt ggttctgcag gatcaatgac atatcacaga ggaggtttct agttggcatt
      181 ctgaagcagt taaatagctt atatttgtta cactatttcc aaaatatcct tcagaccaca
      241 cagggaaagg atttcatcta taacaggtcc cggatcaacc tcagcaagaa agaggggaaa
      301 gttgtgaagt cctccttgaa ccaaatgttg gataaaacag tagaacagaa gatgaaagag
      361 atcttgtact ggtttgcgaa cagcacccag tggaccaagg cgaattatac tctcttactg
      421 ctgcagatgt gcaaccccaa attactgctc actgctgcca atgtgatcag agtcctgttt
      481 ctgagagagg agaacaatat ctcagggctc aatcaagaca tcacagatgt gtgtttttcc
      541 cctgagaaag accacagctc caagtctgcg acctcacaag tctattggac agccaaaact
      601 cagcacacat cccttccttt gtccaaagcc ccagaaaatg aacacttgct tggggcagca
      661 tctaaccctg aggaaccatg gaggaattca ctccggtgta tatccgaaat gaataggctg
      721 ttttctggaa aaggagacat aaccaagcca gggtacgatc cctgcaatct attggttgac
      781 ctggatgaca tcagagacct gtcttctggg ttcagcaaat acctagactt catccgttac
      841 ctgcccatcc acctctccaa gtacattcta agtatgctgg ggtgtatgag gggatttccc
      901 agacacctcc catcttggcc cagttctggg gtttctgggt ccatcttttt ttttccagga
      961 atgctggata gacacaccct gaacaagtgc gcctctgtga gccagcactg ggccgccatg
     1021 gctcaacagg tcaagatgga cttgtcagcg cacggcttca ttcagaacca gattaccttc
     1081 ttgcaggggt cctacacaag aggaattgat cctaattatg ccaataaggt ttctatccca
     1141 gttcctaaaa tggtagatga cgggaagagc atgcgtgtga aacatccgaa gtggaagctg
     1201 agaacgaaga atgagtacaa cctgtggact gcataccaga acgaggaaac gcagcaggtc
     1261 ctgatagagg agagaaatgt tttctgtggg acctacaatg ttcgcattct ctctgacacg
     1321 tgggatcaaa accgagtcat ccactattcc gggggagatc tgatagctgt gtcatctaat
     1381 cgaaagatcc atcttctgga catcatacaa gtgaaagcga tacccgttga attccgaggc
     1441 catgctggga gtgtccgggc cctcttcctg tgtgaggagg aaaactttct cctaagcggg
     1501 agctatgacc taagtatcag atactgggat ctgaaaagtg gggtttgcac acgaatcttc
     1561 ggtggtcacc aggggactat cacttgcatg gacttgtgta agaacaggct cgtatctgga
     1621 ggaagagatt gccaggtaaa agtatgggat gtagacacag ggaagtgcct gaagacgttt
     1681 agacacaaag accccatctt ggccaccagg atcaatgata cctacattgt gagcagctgt
     1741 gagcgagggc tggtgaaagt gtggcacatt gccatggccc agttggtaaa gactctcagt
     1801 ggccatgagg gagccgtgaa atgcctgttc tttgaccagt ggcatctcct ctcaggaagt
     1861 actgatggcc tggtcatggc ctggagcatg gtggggaagt acgagcgctg cctgatggcc
     1921 ttcaagcatc ccaaggaggt gctcgacgtg tccctcctct tcctccgggt catcagcgcc
     1981 tgtgcagatg gcaagatccg aatttacaat ttcctcaacg ggaactgtat gaaggtgtta
     2041 aaagccaatg gcagaggtga tcctgtgctg tccttcttta ttcagggcaa caggatggtg
     2101 gtcaacacag agagcaatgt tctcatgttc cagtttgagc acataaagtg gcagtatgcc
     2161 gtggaaaaaa cgaaacaaaa gaagaataag gagaaagagg aggaaaaaga agaaaatagt
     2221 ctcatggaaa ttctctctaa gtgtaatatt caggttcaca gcccaagaga gtctgtatcc
     2281 agtaaacaaa ctgtgatcca agagctccta ccaggcaaac ctcccaagtc ccgagtactc
     2341 ctgaagccgg ccaagttctc ttcagatgat gtggagaaag cacaaaaaca aggacaattg
     2401 gaaactcctg gaaaactgcc cagtcaccca aagaaaaagt cttggaaaat ccctatgtca
     2461 cctgaccaat tcctcctgac tgttagcgcc ctgcagcacg cccataattc cggggaattt
     2521 gcctatccct gtaggcccca aacagaaatt actgatgtct ggggaccttc aatttcatac
     2581 ccaaggaagg tcttgaattt caaaggaaaa tcaatccaac gtgcagttga tcggttgaga
     2641 ttgagcaatc ctcctataga tgtgaaacga accagtattc cccttgaaat ccagaaactg
     2701 cagcccaact tgaagatctc tttgcacagt cctagagtcc agtccaccat accccagccc
     2761 atgattatcc gctccaggtt ctctggcagc ttaaagggtg gagaccaagt gaccagttca
     2821 attgaaaggg ctgtgtgcag tacgggtccc ctgaccagta tgcaggtcat taaaccaaac
     2881 cgcatgctag ctccacaagt gggcacagcc accctgtctc ttaagaaaga acggcctcgc
     2941 atctatacag cccttgatcc ttttagagtg aacactgagt tcgtgctgtt gaccgtgaag
     3001 gaggagaagg agcaccagga agccaagatg aaggaatatc aggccaggga gtccactgga
     3061 gtggttgatc caggaaaagt cagcaaagct gcatggatca ggaagatcaa aggcctgcct
     3121 attgataatt tcacgaagca agggaaaaca gcggcccctg aacttggaca aaatgtattt
     3181 atc
//
