LOCUS       sequence-414910-        2211 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  A SCHEMA evolved AAV variant effective at targeting subventricular 
            NSCs.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2211)
  AUTHORS   Ojala DS, Sun S, Santiago-Ortiz JL, Shapiro MG, Romero PA, Schaffer 
            DV
  TITLE     In Vivo Selection of a Computationally Designed SCHEMA AAV Library 
            Yields a Novel Variant for Infection of Adult Neural Stem Cells in 
            the SVZ.
  JOURNAL   Mol Ther. 2018 Jan 3;26(1):304-319. doi: 
            10.1016/j.ymthe.2017.09.006. Epub 2017 Sep 8.
  PUBMED    28988711
REFERENCE   2  (bases 1 to 2211)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1016/j.ymthe.2017.09.006"; journalName: "Mol Ther"; date: 
            "2018-01-3- 3"; volume: "26"; issue: "1"; pages: "304-319"
COMMENT     Sequence Label: pAAV SCH9
FEATURES             Location/Qualifiers
     source          1..2211
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             2053..2064
                     /codon_start=1
                     /product="WELQut protease recognition and cleavage site"
                     /label=WELQut site
                     /translation="WELQ"
ORIGIN
        1 atggctgccg atggttatct tccagattgg ctcgaggaca acctctctga gggcattcgc
       61 gagtggtggg acttgaaacc tggagccccg aaacccaaag ccaaccagca aaagcaggac
      121 gacggccggg gtctggtgct tcctggctac aagtacctcg gacccttcaa cggactcgac
      181 aagggggagc ccgtcaacgc ggcggatgca gcggccctcg agcacgacaa ggcctacgac
      241 cagcagctca aagcgggtga caatccgtac ctgcggtata accacgccga cgccgagttt
      301 caggagcgtc tgcaagaaga tacgtctttt gggggcaacc tcgggcgagc agtcttccag
      361 gccaagaaga gggttctcga acctcttggt ctggttgagg aagcggctaa gacggctcct
      421 ggaaagaaga ggcctgtaga gcagtctcct caggaaccgg actcctccgc gggtattggc
      481 aaatcgggtg cacagcccgc taaaaagaga ctcaatttcg gtcagactgg cgacacagag
      541 tcagtcccag accctcaacc aatcggagaa cctcccgcag ccccctcagg tgtgggatct
      601 cttacaatgg cttcaggtgg tggcgcacca gtggcagaca ataacgaagg tgccgatgga
      661 gtgggtagtt cctcgggaaa ttggcattgc gattcccaat ggctggggga cagagtcatc
      721 accaccagca cccgaacctg ggccctgccc acctacaaca atcacctcta caagcaaatc
      781 tccaacagca catctggagg atcttcaaat gacaacgcct acttcggcta cagcaccccc
      841 tgggggtatt ttgactttaa cagattccac tgccactttt caccacgtga ctggcagcga
      901 ctcatcaaca acaactgggg attccggccc aagagactca gcttcaagct cttcaacatc
      961 caggtcaagg aggtcacgca gaatgaaggc accaagacca tcgccaataa cctcaccagc
     1021 accatccagg tctttacgga ctcagactat cagctcccgt acgtgctcgg gtcggctcac
     1081 gagggctgcc tcccgccgtt cccagcggac gttttcatga ttcctcagta cgggtatctg
     1141 acgcttaatg atggaagcca ggccgtgggt cgttcgtcct tttactgcct ggaatatttc
     1201 ccgtcgcaaa tgctaagaac gggtaacaac ttccagttca gctacgagtt tgagaacgta
     1261 cctttccata gcagctacgc tcacagccaa agcctggacc gactaatgaa tccactcatc
     1321 gaccaatact tgtactatct ctcaaagact attaacggtt ctggacagaa tcaacaaacg
     1381 ctaaaattca gtgtggccgg acccagcaac atggctgtcc agggaagaaa ctggcttcct
     1441 ggaccctgtt accgccagca gcgagtatca aagacatctg cggataacaa caacagtgaa
     1501 tactcgtgga ctggagctac caagtaccac ctcaatggca gagactctct ggtgaatccg
     1561 ggcccggcca tggcaagcca caaggacgat gaagaaaagt tttttcctca gagcggggtt
     1621 ctcatctttg ggaagcaagg ctcagagaaa acaaatgtgg acattgaaaa ggtcatgatt
     1681 acagacgaag aggaaatcag gacaaccaat cccgtggcta cggagcagta tggttctgta
     1741 tctaccaacc tccagagagg caacagacaa gcagctaccg cagatgtcaa cacacaaggc
     1801 gttcttccag gcatggtctg gcaggacaga gacgtgtacc tgcaaggacc catttgggcc
     1861 aaaattcctc acacggacgg caactttcac ccttctccgc tgatgggagg gtttggaatg
     1921 aagcacccgc ctcctcagat cctcatcaaa aacacacctg tacctgcgga tcctccaacg
     1981 gccttcaaca aggacaagct gaactctttc atcacccagt attctactgg ccaagtcagc
     2041 gtggagatcg agtgggagct gcagaaggaa aacagcaagc gctggaaccc ggagatccag
     2101 tacacttcca actattacaa gtctaataat gttgaatttg ctgttaatac tgaaggtgta
     2161 tatagtgaac cccgccccat tggcaccaga tacctgactc gtaatctgta a
//
