LOCUS       sequence-418818-         744 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Expresses SARS-CoV-2 Omicron BQ.1.1 RBD (receptor-binding domain 
            from Spike) with N-terminal SpyTag fusion in mammalian cells.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 744)
  AUTHORS   Hills RA, Tan TK, Cohen AA, Keeffe JR, Keeble AH, Gnanapragasam PNP,
            Storm KN, Rorick AV, West AP Jr, Hill ML, Liu S, Gilbert-Jaramillo 
            J, Afzal M, Napier A, Admans G, James WS, Bjorkman PJ, Townsend AR, 
            Howarth MR
  TITLE     Proactive vaccination using multiviral Quartet Nanocages to elicit 
            broad anti-coronavirus responses.
  JOURNAL   Nat Nanotechnol. 2024 May 6. doi: 10.1038/s41565-024-01655-9.
  PUBMED    38710880
REFERENCE   2  (bases 1 to 744)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Nat 
            Nanotechnol. 2024 May 6. doi: 10.1038/s41565-024-01655-9."
COMMENT     Sequence Label: SpyTag-RBD Omicron BQ.1.1
FEATURES             Location/Qualifiers
     source          1..744
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             73..111
                     /codon_start=1
                     /product="peptide derived from the CnaB2 adhesin domain of 
                     Streptococcus pyogenes FbaB"
                     /label=SpyTag
                     /note="forms a covalent isopeptide bond with the SpyCatcher
                     protein (Zakeri et al., 2012)"
                     /translation="AHIVMVDAYKPTK"
ORIGIN
        1 atgaacaccc agatcctggt gttcgccctg atcgccatca ttcccaccaa cgccgacaag
       61 atcggatctg gcgcccacat cgtgatggtg gacgcctaca agcctaccaa aggcagcggt
      121 ggaagcggcg gatctggaac cggtaatatt acgaacctgt gtccattcga tgaagtgttc
      181 aatgctacca ccttcgctag cgtctatgcc tggaaccgga agaggatatc caattgcgtg
      241 gctgactata gtgtgcttta caatttcgct cccttctttg cctttaaatg ctatggcgtt
      301 tctccaacaa aattgaacga tttgtgcttc accaacgtct atgccgactc tttcgtgatt
      361 cggggaaacg aagtaagtca aattgcgcca ggacaaacag gtaatattgc cgattacaat
      421 tataagctcc ccgacgattt tacgggttgc gtgatcgcat ggaactccaa taaactggat
      481 tcaacagtag gggggaatta taattaccgc taccggctgt ttcggaagag caaactgaaa
      541 ccgtttgagc gggatattag tacggaaatt taccaggcgg ggaataaacc ttgtaatggg
      601 gtggccgggg tgaattgtta ttttcccctg cagagttatg gctttcgccc gacatacgga
      661 gttggccatc aaccttaccg agtcgtagta ttgtctttcg agcttcttca cgcgccagcc
      721 acagtgtgtg ggcctaagaa atag
//
