LOCUS       sequence-420162-         888 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  E. coli expression of BirA tagged HLA-A*02:01 containing a cysteine 
            mutation for disulfide linkage to mutant beta-2 microglobulin..
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 888)
  AUTHORS   Sun Y, Young MC, Woodward CH, Danon JN, Truong HV, Gupta S, Winters 
            TJ, Font-Burgada J, Burslem GM, Sgourakis NG
  TITLE     Universal open MHC-I molecules for rapid peptide loading and 
            enhanced complex stability across HLA allotypes.
  JOURNAL   Proc Natl Acad Sci U S A. 2023 Jun 20;120(25):e2304055120. doi: 
            10.1073/pnas.2304055120. Epub 2023 Jun 13.
  PUBMED    37310998
REFERENCE   2  (bases 1 to 888)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Proc Natl 
            Acad Sci U S A."; date: "2023-06-20"; volume: "120(25):e2304055120. 
            doi"; pages: " 10.1073/pnas.2304055120. Epub 2023 Jun 13"
COMMENT     Sequence Label: OPEN HLA-A*02:01-BirA
FEATURES             Location/Qualifiers
     source          1..888
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 catatgggca gtcatagcat gcgctacttc ttcaccagcg tgagtcgtcc tggtcgtggc
       61 gaaccgcgct tcatcgccgt tggttacgtt gacgacaccc aattcgtgcg cttcgatagc
      121 gacgcagcca gtcagcgtat ggaaccgcgc gcaccgtgga tcgagcagga aggtccggag
      181 tactgggacg gcgaaacccg caaggttaaa gcccacagcc agacccatcg tgtggatctg
      241 ggcaccctgc gcggctacta caaccagagt gaggccggca gccacaccgt gcaacgcatg
      301 tatggctgtg acgtgggtag cgactggcgc ttcctgcgtg gctaccatca gtacgcctac
      361 gactgcaagg attacatcgc cctgaaagag gacttacgca gctggacagc agcagacatg
      421 gccgcccaga ccaccaagca caaatgggaa gcagcccatg tggccgagca gctgcgtgca
      481 tatctggagg gtacctgcgt tgagtggctg cgccgctacc tggagaacgg taaggagacc
      541 ctgcagcgca ccgacgcacc gaaaacccac atgacccacc acgccgttag cgatcacgaa
      601 gccacactgc gctgctgggc cctgagtttc tacccggccg agatcaccct gacctggcaa
      661 cgtgacggcg aggaccagac ccaggacacc gaactggttg agacacgccc tgccggtgac
      721 ggcacatttc agaaatgggc cgccgttgtg gtgccgagcg gtcaagagca gcgctacacc
      781 tgccacgtgc agcatgaagg cctgccgaag cctttaaccc tgcgctggga gccgggatcc
      841 ctgcatcata ttctggatgc acagaaaatg gtgtggaatc atcgttaa
//
