LOCUS       sequence-433717-        4593 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Gateway entry clone with codon-optimized ORF sequence for subcloning
            into custom expression vectors.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 4593)
  AUTHORS   Wolf G, Craigon C, Teoh ST, Essletzbichler P, Onstein S, Cassidy D, 
            Uijttewaal ECH, Dvorak V, Cao Y, Bensimon A, Elling U, Ciulli A, 
            Superti-Furga G
  TITLE     The efflux pump ABCC1/MRP1 constitutively restricts PROTAC 
            sensitivity in cancer cells.
  JOURNAL   Cell Chem Biol. 2024 Dec 24:S2451-9456(24)00489-6. doi: 
            10.1016/j.chembiol.2024.11.009.
  PUBMED    39755121
REFERENCE   2  (bases 1 to 4593)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Cell Chem 
            Biol. 2024 Dec 24:S2451-9456(24)00489-6. doi: 
            10.1016/j.chembiol.2024.11.009."
COMMENT     Sequence Label: pENTR-ABCC1_STOP
FEATURES             Location/Qualifiers
     source          1..4593
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggcactcc gaggcttttg tagcgcagat ggcagcgacc ccctgtggga ttggaatgta
       61 acatggaata caagcaaccc tgacttcaca aaatgttttc aaaatacagt actcgtctgg
      121 gtcccctgct tctacttgtg ggcatgtttc cccttctact tcttgtatct ctccaggcac
      181 gataggggat acatccaaat gacccctctg aataaaacca aaactgctct gggcttcctg
      241 ttatggatag tctgctgggc cgacttattt tattcctttt gggagcgctc aaggggcatc
      301 ttcctcgccc ccgttttcct tgtatctcct acgttgcttg gaatcactat gttattagct
      361 actttcctga tccaactcga aagaagaaaa ggggttcaaa gcagtggaat aatgctcacc
      421 ttttggctcg tagccttggt gtgcgcactc gcaatcttga ggtcaaagat catgactgca
      481 ctgaaggaag atgcccaagt agatttgttt cgcgacataa ctttctacgt gtatttctca
      541 cttcttctga tccaactggt cctttcttgc ttctccgatc ggagcccttt attttccgag
      601 accatccatg acccaaaccc ttgtccagag agctctgcga gtttcttatc taggatcacc
      661 ttctggtgga tcaccggttt aatcgttcgc ggttatcggc agccgcttga gggctctgac
      721 ctttggagtc ttaacaaaga ggatacgtca gaacaagtgg ttcctgtact ggtgaagaat
      781 tggaagaaag aatgtgccaa aactcgcaag caacccgtta aagtagtgta ttctagcaag
      841 gatcccgccc agccgaaaga gtcatccaaa gtggatgcca atgaggaagt tgaagcattg
      901 attgtaaagt ctcctcagaa agagtggaac ccttcattgt ttaaggttct gtataagaca
      961 tttggtccct actttctgat gtctttcttc ttcaaagcga tccatgacct tatgatgttt
     1021 tcaggtcccc aaattctgaa gttacttatt aagtttgtga atgataccaa ggcaccggat
     1081 tggcaggggt atttctacac tgttctcctg tttgtaacag cgtgccttca aacactcgtc
     1141 ttacaccagt atttccacat atgcttcgtg tcaggaatga ggattaagac agccgttatc
     1201 ggtgctgtct acagaaaggc tctcgtcatc actaacagcg cgagaaaatc ttccacagtg
     1261 ggtgaaattg tgaacctgat gagcgtggat gcgcaaagat ttatggacct cgccacctat
     1321 attaacatga tatggagcgc acccctgcag gtcatattgg cactctactt gctttggttg
     1381 aacctgggtc caagtgttct ggctggtgtt gctgtgatgg tgttgatggt acccgttaac
     1441 gccgtcatgg ccatgaagac taagacatat caagtcgctc atatgaaatc caaggacaac
     1501 cgaataaaac tcatgaacga aatcctgaat ggtattaaag tgcttaaact gtatgcttgg
     1561 gaactggctt tcaaagataa ggtcttggct atccgtcaag aagaattgaa agttcttaag
     1621 aaatcagctt acctctcagc cgtcggcacg ttcacctggg tctgcacacc ctttctggtg
     1681 gccttgtgta ctttcgccgt atatgtcact attgacgaga acaatatcct ggacgcacaa
     1741 accgcctttg tatccctcgc gctgtttaac attctccggt ttccgcttaa tatcttgcct
     1801 atggtgatct caagtattgt ccaagccagt gtctctctga aacggctccg catctttctg
     1861 tctcatgagg agttggaacc agattctata gaacgccgac ccgtgaaaga cggcggcggg
     1921 accaacagca taactgtcag aaacgcaaca ttcacatggg ctcgcagtga cccgcccacc
     1981 ctcaatggca ttacattctc cattccggaa ggcgcattag tcgcagtggt ggggcaagtt
     2041 ggatgtggca agtccagcct gctctccgct ctgcttgccg agatggacaa agttgaggga
     2101 catgtcgcta taaaagggtc tgtcgcatat gtcccccaac aagcctggat acagaatgat
     2161 tctttacgag agaacatatt gtttggatgt caactcgaag aaccctatta ccggtccgtt
     2221 attcaagcat gtgctctctt gcctgacctc gagattcttc ccagcggcga ccgtacagag
     2281 atcggcgaga aaggcgtcaa tctctctggt ggccaaaagc agcgcgtcag cttggcacgt
     2341 gccgtgtatt ctaatgctga tatttatctg ttcgatgatc cactctctgc cgtggatgcc
     2401 catgtgggga aacacatatt cgagaatgta atagggccca agggtatgct taagaataaa
     2461 actaggattc tggtaaccca tagtatgtct tatttgccac aagttgatgt cattatcgtc
     2521 atgtctggcg gaaagattag tgagatgggc tcttaccaag aactgctggc ccgggacggg
     2581 gcctttgccg aattcctgcg tacttacgcc tcaacggaac aggagcagga tgctgaggag
     2641 aatggagtaa ccggagttag cgggccaggt aaagaggcta aacaaatgga gaacgggatg
     2701 ttagtcactg actctgcagg aaaacaactg caacgccagc tgagcagcag cagtagctat
     2761 tccggcgaca tttcccgaca ccacaactct actgcggaac ttcagaaagc ggaagctaag
     2821 aaagaggaaa cttggaaact gatggaagct gataaggctc aaaccgggca agtgaaactg
     2881 tctgtttatt gggattatat gaaggccatt gggttgttta ttagcttcct gtcaattttc
     2941 ctgttcatgt gtaatcatgt ttcagcttta gcctctaact attggctttc tctctggacc
     3001 gatgatccta ttgttaatgg tactcaagag catactaaag taaggctcag cgtgtatggt
     3061 gccctgggca taagccaagg tatcgccgta tttgggtaca gcatggctgt atccatcggt
     3121 ggaatcctcg cgtcacgctg ccttcatgtc gacttgttac attcaatact gaggagtcct
     3181 atgtccttct ttgaaagaac acctagcgga aacctggtca accgattttc aaaggaactg
     3241 gatactgtcg actccatgat tcctgaggtt attaaaatgt ttatgggctc tttatttaac
     3301 gtgattggag cctgtatcgt catcctgctt gccacgccaa tcgcagcgat aatcattcca
     3361 cccctgggac ttatctactt ctttgtgcaa cgcttctacg tggcgtcatc ccgacagctc
     3421 aaacgcctgg aaagcgtctc cagaagccca gtgtactcac atttcaacga gaccctgctt
     3481 ggggtttccg tgataagggc tttcgaggaa caggaacgct ttatacatca atccgacttg
     3541 aaagtggatg agaaccaaaa ggcctattat ccgtccatag tagcaaacag gtggctggct
     3601 gtacgtctgg agtgcgtggg aaattgcatt gttctgtttg cagctttatt tgccgttata
     3661 tccaggcaca gtctctcagc cgggctcgtt gggttgtctg tcagctactc actgcaagtg
     3721 acgacttatc ttaattggct tgtgcgcatg agctcagaaa tggaaacaaa tatcgtagca
     3781 gttgaacggc ttaaagaata ctcagaaaca gagaaagagg caccttggca aatacaagaa
     3841 actgcaccac cttccagttg gcctcaagtc ggccgggtcg agttcagaaa ttattgtctg
     3901 aggtatcgag aagacctgga ctttgtgctg agacatatta atgttaccat taatggcggt
     3961 gaaaaggtcg ggattgtagg aaggactggt gcaggtaaat ccagccttac gttaggcctt
     4021 ttccgtatca acgaatccgc tgaaggcgag atcataatag atgggattaa tatagccaaa
     4081 atcggccttc atgatcttcg cttcaagatc actatcatcc ctcaggaccc cgttttgttt
     4141 tctggaagct tacgcatgaa cttggatcca ttctcacagt attccgacga agaagtgtgg
     4201 acttcactcg aattggcgca cctgaaggac tttgtgagcg ctttgccaga caagctcgac
     4261 catgaatgtg ccgaaggcgg tgagaactta agcgtaggcc aacgtcagtt agtttgcctt
     4321 gctcgggcgc tgctccgaaa gactaagatt ctcgtattag atgaagccac tgcggcagtt
     4381 gaccttgaaa cagatgacct catacagagc acgatcagaa cgcaatttga agactgtaca
     4441 gttctcacca tcgcgcatag acttaacacc attatggatt acacaagagt cattgtgtta
     4501 gacaagggtg agatccaaga gtacggggcc ccaagtgatc tgttacaaca acgagggctg
     4561 ttctactcta tggcaaagga cgccggatta gta
//
