LOCUS       sequence-44923-e         755 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 755)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 755)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-BRAF
FEATURES             Location/Qualifiers
     source          1..755
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 gggacggaac tgatttttct gtttctagct ctgcatcaat ggataccgtt acatcttctt
       61 cctcttctag cctttcagtg ctaccttcat ctctttcagt ttttcaaaat cccacagatg
      121 tggcacggag caaccccaag tcaccacaaa aacctatcgt tagagtcttc ctgcccaaca
      181 aacagaggac agtggtacct gcaaggtgtg gagttacagt ccgagacagt ctaaagaaag
      241 cactgatgat gagaggtcta atcccagagt gctgtgctgt ttacagaatt caggatgggt
      301 cttttctgga gctgacttga agaaaagagt acatctcttt accctgctgt ttgtccaaga
      361 gtgatacatt tatttgggag agaagaaacc aattggttgg gacactgata tttcctggct
      421 tactggagaa gaattgcatg tggaagtgtt ggagaatgtt ccacttacaa cacacaactt
      481 tgtacgaaaa acgtttttca ccttagcatt ttgtgacttt tgtcgaaagc tgcttttcca
      541 gggtttccgc tgtcaaacat gtggttataa atttcaccag cgttgtagta cagaagttcc
      601 actgatgtgt gttaattatg accaacttga tttgctgttt gtctccaagt tctttgaaca
      661 ccacccaata ccacaggaag aggcgtcctt agcagagact gccctaacat ctggatcatc
      721 cccttccgca cccgcctcgg actctattgg gcccc
//
