LOCUS       sequence-460273-       24334 bp    DNA     circular SYN 15-DEC-2025
DEFINITION  Module for the expression of the N. nambi HISPS gene under the 
            regulation of PMTB and TNOS and the constitutive expression of 
            CPH,LUZ, H3H, EGFP and p19.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      synthetic DNA construct
  ORGANISM  synthetic DNA construct
REFERENCE   1  (bases 1 to 24334)
  AUTHORS   Calvache C, Vazquez-Vilar M, Moreno-Gimenez E, Orzaez D
  TITLE     A quantitative autonomous bioluminescence reporter system with a 
            wide dynamic range for Plant Synthetic Biology.
  JOURNAL   Plant Biotechnol J. 2024 Jan;22(1):37-47. doi: 10.1111/pbi.14146. 
            Epub 2023 Oct 26.
  PUBMED    37882352
REFERENCE   2  (bases 1 to 24334)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10.1111/pbi.14146";
            journalName: "Plant Biotechnol J"; date: "2024-01"; volume: "22"; 
            issue: "1"; pages: "37-47"
COMMENT     Sequence Label: GB4402
FEATURES             Location/Qualifiers
     source          1..24334
                     /mol_type="other DNA"
                     /organism="synthetic DNA construct"
     CDS             complement(2081..2092)
                     /codon_start=1
                     /product="Factor Xa recognition and cleavage site"
                     /label=Factor Xa site
                     /translation="IEGR"
     terminator      7288..7540
                     /label=NOS terminator
                     /note="nopaline synthase terminator and poly(A) signal"
     promoter        8384..8728
                     /label=CaMV 35S promoter
                     /note="strong constitutive promoter from cauliflower mosaic
                     virus"
     RBS             8856..8864
                     /label=Shine-Dalgarno sequence
                     /note="full consensus sequence for ribosome-binding sites 
                     upstream of start codons in E. coli; complementary to a 
                     region in the 3' end of the 16S rRNA (Chen et al., 1994)"
     terminator      9746..9998
                     /label=NOS terminator
                     /note="nopaline synthase terminator and poly(A) signal"
     promoter        10842..11186
                     /label=CaMV 35S promoter
                     /note="strong constitutive promoter from cauliflower mosaic
                     virus"
     CDS             complement(11556..11567)
                     /codon_start=1
                     /product="Factor Xa recognition and cleavage site"
                     /label=Factor Xa site
                     /translation="IEGR"
     terminator      12087..12339
                     /label=NOS terminator
                     /note="nopaline synthase terminator and poly(A) signal"
     promoter        13183..13527
                     /label=CaMV 35S promoter
                     /note="strong constitutive promoter from cauliflower mosaic
                     virus"
     terminator      14893..15145
                     /label=NOS terminator
                     /note="nopaline synthase terminator and poly(A) signal"
     promoter        15989..16333
                     /label=CaMV 35S promoter
                     /note="strong constitutive promoter from cauliflower mosaic
                     virus"
     CDS             join(16407..16409,16410..16412,16413..17123)
                     /codon_start=1
                     /product="enhanced GFP"
                     /label=EGFP
                     /translation="MVSKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTL
                     KFICTTGKLPVPWPTLVTTLTYGVQCFSRYPDHMKQHDFFKSAMPEGYVQERTIFFKDD
                     GNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQKNGIK
                     VNFKIRHNIEDGSVQLADHYQQNTPIGDGPVLLPDNHYLSTQSALSKDPNEKRDHMVLL
                     EFVTAAGITLGMDELYK"
     CDS             join(16407..16409,16410..16412,16413..17123)
                     /codon_start=1
                     /product="the original enhanced GFP (Yang et al., 1996)"
                     /label=EGFP
                     /note="mammalian codon-optimized"
                     /translation="MVSKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTL
                     KFICTTGKLPVPWPTLVTTLTYGVQCFSRYPDHMKQHDFFKSAMPEGYVQERTIFFKDD
                     GNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQKNGIK
                     VNFKIRHNIEDGSVQLADHYQQNTPIGDGPVLLPDNHYLSTQSALSKDPNEKRDHMVLL
                     EFVTAAGITLGMDELYK"
     primer_bind     complement(16452..16473)
                     /label=EGFP-N
                     /note="EGFP, reverse primer"
     primer_bind     complement(16713..16732)
                     /label=EXFP-R
                     /note="For distinguishing EGFP variants, reverse primer"
     primer_bind     17060..17081
                     /label=EGFP-C
                     /note="EGFP, forward primer"
     terminator      17159..17411
                     /label=NOS terminator
                     /note="nopaline synthase terminator and poly(A) signal"
     misc_feature    17653..17677
                     /label=RB T-DNA repeat
                     /note="right border repeat from nopaline C58 T-DNA"
     CDS             18978..19607
                     /codon_start=1
                     /product="stability protein from the Pseudomonas plasmid 
                     pVS1 (Heeb et al., 2000)"
                     /label=pVS1 StaA
                     /translation="MKVIAVLNQKGGSGKTTIATHLARALQLAGADVLLVDSDPQGSAR
                     DWAAVREDQPLTVVGIDRPTIDRDVKAIGRRDFVVIDGAPQAADLAVSAIKAADFVLIP
                     VQPSPYDIWATADLVELVKQRIEVTDGRLQAAFVVSRAIKGTRIGGEVAEALAGYELPI
                     LESRITQRVSYPGTAAAGTTVLESEPEGDAAREVQALAAEIKSKLI"
     CDS             20036..21109
                     /codon_start=1
                     /product="replication protein from the Pseudomonas plasmid 
                     pVS1 (Heeb et al., 2000)"
                     /label=pVS1 RepA
                     /translation="MSGRKPSGPVQIGAALGDDLVEKLKAAQAAQRQRIEAEARPGESW
                     QAAADRIRKESRQPPAAGAPSIRKPPKGDEQPDFFVPMLYDVGTRDSRSIMDVAVFRLS
                     KRDRRAGEVIRYELPDGHVEVSAGPAGMASVWDYDLVLMAVSHLTESMNRYREGKGDKP
                     GRVFRPHVADVLKFCRRADGGKQKDDLVETCIRLNTTHVAMQRTKKAKNGRLVTVSEGE
                     ALISRYKIVKSETGRPEYIEIELADWMYREITEGKNPDVLTVHPDYFLIDPGIGRFLYR
                     LARRAAGKAEARWLFKTIYERSGSAGEFKKFCFTVRKLIGSNDLPEYDLKEEAGQAGPI
                     LVMRYRNLIEGEASAGS"
     rep_origin      21175..21369
                     /label=pVS1 oriV
                     /note="origin of replication for the Pseudomonas plasmid 
                     pVS1 (Heeb et al., 2000)"
     primer_bind     complement(21605..21627)
                     /label=pGEX 3'
                     /note="pGEX vectors, reverse primer"
     misc_feature    21713..21853
                     /label=bom
                     /note="basis of mobility region from pBR322"
     primer_bind     21768..21787
                     /label=pRS-marker
                     /note="pRS vectors, use to sequence yeast selectable 
                     marker"
     primer_bind     complement(21868..21885)
                     /label=L4440
                     /note="L4440 vector, forward primer"
     rep_origin      complement(22039..22627)
                     /direction=LEFT
                     /label=ori
                     /note="high-copy-number ColE1/pMB1/pBR322/pUC origin of 
                     replication"
     primer_bind     complement(22119..22138)
                     /label=pBR322ori-F
                     /note="pBR322 origin, forward primer"
     CDS             complement(22715..23506)
                     /codon_start=1
                     /gene="aadA"
                     /product="aminoglycoside adenylyltransferase (Murphy, 
                     1985)"
                     /label=SmR
                     /note="confers resistance to spectinomycin and 
                     streptomycin"
                     /translation="MREAVIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKPH
                     SDIDLLVTVTVRLDETTRRALINDLLETSASPGESEILRAVEVTIVVHDDIIPWRYPAK
                     RELQFGEWQRNDILAGIFEPATIDIDLAILLTKAREHSVALVGPAAEELFDPVPEQDLF
                     EALNETLTLWNSPPDWAGDERNVVLTLSRIWYSAVTGKIAPKDVAADWAMERLPAQYQP
                     VILEARQAYLGQEEDRLASRADQLEEFVHYVKGEITKVVGK"
     misc_feature    24292..24316
                     /label=LB T-DNA repeat
                     /note="left border repeat from nopaline C58 T-DNA"
ORIGIN
        1 ggagctcaat ggtaacttta ctctttattt aaccatacat ttttttttat ttttttcact
       61 ttgttcttca tccactattg ttctttgttc atcttgaaca aaagctccct ccttctttgt
      121 tcttcatcca ccattgttct tcatcaatca tttcgctgtc aggagtatct tactttttga
      181 ttttattaat atttgaacaa acttcatatc gatcaagtaa ctattagtat ttgcgtttca
      241 tacaaaagtt atataactag tttctctaac ccaaagtcac taaattttga gatacaaaca
      301 aaaaagtcac aaagtcaaaa catatcatat ctacaaagta tcattatttt tagcggaaaa
      361 tacattattt ctgacatact actttgtata cataacgaat aatgacataa ctatgtcatt
      421 aattaattga atgtgtcaaa gtacaaattc atctagaaat acttttatct tggatgtgta
      481 ataatatgaa gttattatat caagctactt atacaaagag gaagattgaa caagcatgac
      541 atctacacat ttcttaatca ttttatcgta tataattaaa cacatttcat taacaaaata
      601 atcatttaat tcttcatttt ctattaaaat tagaacttat ttaattatct tacaatattt
      661 tttatcaata ctcttcaatg atcatcttat tcattaaaca caacttaatt aatcatatta
      721 aacataaact tgtgtagtca attatgaaca tacttgtgta gattttgggc cacaaattat
      781 tggtatctac caagttctag agaaaaaata atacgtgaaa aaaatattct cgaaacgtaa
      841 acattaacta tttttatgct aaaagtacta tattgaatta ttatttttgt ttcctatgta
      901 acataaatat ttaaatttta tcatcacttt ttgaaaaata attttaattt ttacatgtta
      961 aattatttaa ataaatatca tattatttga gataaataaa aagaataaac attaacaact
     1021 taaaccaagg tacgtgcatg cccacaattt gttccaacag aaaatgttat ttccttgggt
     1081 agataagaag tcactatcaa tttggtcgat taattcagaa atttatcgag aaattcgtag
     1141 ttgttacttt tttatagcat attaagtaac ttatttttgt ataagaattt acaaatcaca
     1201 ttaataatat atatcgtatt aaataaattg aacctgatga attcaattaa aatgacataa
     1261 cagattaaat tgaaccctaa tctttcttga tatcgagtgt gtttggtatg aaggaaccag
     1321 aaagtgtttt ccaattttct catgtttggt tgggacaaaa attttgaaaa aagtttttcg
     1381 aatcaactca ttttcctcaa aattaagaaa aatgatttcc tttaaaaaat taaggaaaac
     1441 atttttccaa actctcctca aatttaaaat tacattttta ttttaggaaa aacaacaatc
     1501 tttttaaaaa aatttaattc taaattattt ttttagccga tccctgacca ccacccaaac
     1561 gcacctatca tctcatatgc tacatcagct cgatcacaat atacttcatt tgtttcgatt
     1621 tatgtgacac ttttcgtttt tcaagagtca aataattaaa gtttgaccga aaacatacgc
     1681 gcgaaatttt ctatttttta aaataaaatt tatacaacta tataaaaagt actataggtc
     1741 acaataactg ttaattcaaa ataaataaaa ataaatataa aaaatttaca atcaaagata
     1801 aaatcattta aatcttgaaa agtgtcaaaa tataaagtta tttagtttgt tataaacatt
     1861 cgatatagat aaataagtcg cggtcgatag agaatgtaaa tatgtctaga acatacgtac
     1921 gaatggtaat tgtgattata gaaaacgacg aatacgtgga tgaaattagg atcatgtatg
     1981 gaccgactta caaggataac atattcccat acgatcacga cacgtgtacg gttaatatca
     2041 tccatgtacc ttcgtttcac tataaataga cactcatgct tcttccctca atcactcatt
     2101 tctacaccaa tcaaaaaaaa aaaaaatcac atttgatttc tcaattcttg tttcagacca
     2161 atcatcaatg aactcaagta aaaatcctcc ttctactctc cttgatgttt tcttggatac
     2221 cgcaagaaac ttggatacag caagcagaaa tgtgctcgag tgtggtgaac atcgatggag
     2281 ttacagagaa ctggatacag tgtcctcagc tctcgcccag catcttcgat acacggtggg
     2341 gctgtcccct actgtcgcag tgatcagcga gaatcacccg tacatattgg ccctcatgct
     2401 cgctgtatgg aaattgggcg gtaccttcgc tccgatagat gtccacagcc ctgcagaact
     2461 ggttgccggg atgcttaaca tagtctcacc gtcttgcctg gtcatcccgt catcagacgt
     2521 aacaaaccag acccttgcat gtgatcttaa cattccagtg gttgcatttc atcctcacca
     2581 aagcacaatc ccggaactga acaaaaagta cctgacggac agtcaaatca gccctgatct
     2641 cccattcccc gatcccaacc gtccggctct ttacctgttc acttcttctg ctacgagtag
     2701 atccaacttg aagtgcgtgc ccctgaccca caccttcata ctgagaaata gcctgtcaaa
     2761 gagggcctgg tgcaaaagaa tgaggccaga aacagatttc gatggtataa gggttttagg
     2821 atgggcacca tggagtcatg ttctggctca catgcaagat atagggcccc ttacactcct
     2881 gaatgctgga tgttacgtct ttgcaacgac accgagcaca tatccaaccg agttgaagga
     2941 cgatagggat gtcatttctt gcgccgcaaa tgcagttatg tacaaggggg ttaagtcctt
     3001 cgcctgtctc ccgtttgtgc tgggaggcct taaggccctg tgtgagtccg agccgtccgt
     3061 caaagcacaa ttacaggtcg aggagcgagc acagttgtta aagagcttac aacacatgaa
     3121 gattcttgaa tgtggtggcg ctatgctcga agtttcagtg gcttcttggg ctatcgagaa
     3181 tcgtattccc attagtatag gaatcggtat gaccgaaact ggcggagcct tgttcgctgg
     3241 acccgttcaa gcaatccaaa cgggatttag ttcagaggac aagtttattg aggatgccac
     3301 atatctcctt gtcaaagacg attacgagtc acacgcagaa gaggacatca atgaaggcga
     3361 actggttgtt aaaagccgaa tgctgccaag gggttatctg gggtataacg atccatcctt
     3421 ctcagtggac gatgcagggt gggttacctt caaaacaggc gacaggtact ccgtgacccc
     3481 ggatggtaag ttttcttggt taggaaggaa tacagacttt atacagatga caagcggtga
     3541 gactctcgat cccaggccca tcgaaagttt gctttgcgag tcctccctta tatcaagagc
     3601 ctgtgtaata ggcgataagt tcctgaatgg gcccgccaca gcagtgtgtg ccataataga
     3661 attggagccg actacggtag agaaaggtca ggcccatagc agggacatag cccgaatttt
     3721 tgcccccata aaccgtgatt tgcctcctcc tttaagaatc gcctggagcc acgtcctcgt
     3781 gctccaaccc agtgaaaaaa taccgatgac caaaaaagga acgatcttcc gtaagaagat
     3841 cgaacaagtc tttggtagtg cacttggtgg gtcctcaggt gacaattccc aagcaaccac
     3901 tgatgcatca gtcgtccgtc gagatgaact gtcaaacact gttaagcata tcatatcacg
     3961 tgttctgggc gtgagcgacg acgagttgct gtggactctc tcatttgccg aacttggaat
     4021 gacctccgcc cttgcaacga gaattgccaa tgaattgaat gaggttttag taggggtcaa
     4081 tctgcctatc aatgcatgtt atatacacgt tgacttacca tccctgtcaa atgcagtata
     4141 tgccaaactg gctcacttga aactccctga cagaacacca gagccgcgta aggcaccggt
     4201 tgagaatcct ggcggaaaag agatcgtaat agtgggacaa gcatttagac ttccaggctc
     4261 tattaatgac gtggctagtc tccgtgacgc ttttctggcc cgtcaagcaa gttcaatcat
     4321 tacagaaata ccaccagaca gatgggatca cgcatccttc tacccgaagg acatacgttt
     4381 caacaaggcc ggcttagtgg acattgctaa ctacgaccac agtttcttcg gcttgacggc
     4441 tacagaagct ctttacttat ctccgaccat gagactcgcc ctggaagtta gttttgaggc
     4501 ccttgagaac gcaaacattc cggtttctca gctgaagggg tcacaaacag ctgtctacgt
     4561 tgctaccacg gatgacgggt tcgagactct cttaaatgca gaggctgggt acgacgctta
     4621 cacccgattc tacggtacgg ggcgtgcagc ttccacggca tccggcagga tctcatacct
     4681 gcttgacgtt catggaccca gtataactgt ggacacggca tgtagtggag gggctgtttg
     4741 cattgatcaa gctatagact acctgcaatc cagttcagcc gctgataccg ccatcatttg
     4801 tgcttctaat actcattgct ggccaggatc attcatgttt ctgagcgccc agggtatggt
     4861 aagctccggc ggacgatgcg ctactttcac gaccgatgcc gacggctacg tacctagcga
     4921 gggtgcagtc gccttcattc ttaaaacacg tgaagcagct atgagggaca aagacacaat
     4981 tctggctacc atcaaagcaa cacaaatttc tcataatggt aggtcccagg gattagtcgc
     5041 ccccaatgta aattcccaag ccgacttgca tagaagcctg ctccaaaaag ccgggctttc
     5101 accggccgac attcatttca tcgaggcaca cggaactgga acctccctcg gagatctgtc
     5161 cgagatccaa gctataaatg atgcatatac gagctcacaa cctcgaacgg ccggcccgct
     5221 gatcgtttct gcaagcaaga cagtgatagg acacactgaa ccagccggtc cgttggtggg
     5281 gatgctgtca gtactgaact cctttaaaga gggggccgtc cctggtttgg cacacttgac
     5341 cgccgataac ctgaatcccg ctcttgattg cagcagtgtt ccgttactca taccttacca
     5401 gcccgttcac ctggcagccc ccaagcctca tcgtgctgct gtaatgtcat atggattctc
     5461 tggcaccctc ggtgggatcg tgctggaggc accagatgag gaaagactcg aagaggaacc
     5521 tcctaatgac aaacctatgt tgtttgtagt tagtgcaaaa acacatactg cattaataga
     5581 atatctcggc cgataccttg aattcctctt gcaggcaaat ccacaagact tctgcgatat
     5641 ttgttatact tcatgcgttg ggcgtgaaca ttatcgatac agattcgcat gcgtagccaa
     5701 cgacatggag gatttaatag gacaattgca gaagcgttta ggctctaagg tcccaccgaa
     5761 accttcctac aaaagagggg cccttgcatt cgccttcagc ggtcagggca cacagttccg
     5821 agggatggct accgagctcg caaaagccta ttccggattc cgaaaaatag tctctgatct
     5881 cgctaagagg gcaagtgaac tctcaggtca cgctattgat cgatttttgt tagcttacga
     5941 tattggggct gaaaacgtcg ccccggatag cgaggctgat caaatatgta tcttcgtata
     6001 tcaatgtagc gtgcttcgtt ggcttcagac aatgggcatt agaccatctg ctgttatagg
     6061 gcactccctc ggtgagatta gcgcttctgt cgccgccggt gcattgtctc tggactctgc
     6121 actggacctt gttatcagtc gagctcgact gttaaggagc tctaccaatg cacccgccgg
     6181 tatggcagcc atgtcagcat cacaggacga agttgttgag ttgattggga aattagacct
     6241 tgataaagca aattcactct ctgtttctgt tatcaatggt cctcagaata cggtagtaag
     6301 cggttcttca gcagccattg aaagtatagt cgcactggcc aaagggcgaa agataaaagc
     6361 aagtgctctc aacatcaacc aagccttcca ctctccctac gtagattctg cagtaccagg
     6421 tttgcgtgct tggtcagaga agcatatttc ctctgctaga ccattacaga tccccctgta
     6481 ctctacactc cttggcgccc aagtaagtga gggacaaatg ctgaatccgg atcattgggt
     6541 agatcacgca agaaaacctg tccaattcgc tcaggccgcc accattatga aagaaagctt
     6601 taccggagta atcattgaca taggtcctca agtagttgct tggagtttgc tgctctcaaa
     6661 cggactgaca tcagttaccg ctctcgccgc aaagcgagga cgatcacagc aggttgcctt
     6721 ccttagtgct cttgcagatt tataccaaga ctatggtgtc gtgcctgact ttgtgggatt
     6781 atacgctcaa caggaggacg ccagtcgttt aaagaaaacc gatattctga cctatccttt
     6841 ccaaagggtg agaaggtatc catctttcat cccgagtcgt agggcaccta ctcatgccca
     6901 tgtccaagat gaggaaacat tgtcatctgg atcttccaca cccacattgg agaatacaga
     6961 tctcgactcc ggtaaagagt ctttgatggg acccacacgt ggccttcttc gagtagacga
     7021 tctgagagac agtatcgttt cttctgtaaa ggatgtactg gagctgaaat caaatgagga
     7081 cttggacttg tccgagtcct tgaacgcatt gggaatggac agtattatgt tcgctcaatt
     7141 acgtaaaagg ataggggagg gactcgggtt atccgtcccg atggtattcc tgtctgacgc
     7201 cttctcaatc ggcgagatgg ttagtaacct tgtagaacag gcagaggcta gtgaggacaa
     7261 ctgagcttgg aatggatctt cgatcccgat cgttcaaaca tttggcaata aagtttctta
     7321 agattgaatc ctgttgccgg tcttgcgacg attatcatat aatttctgtt gaattacgtt
     7381 aagcatgtaa taattaacat gtaatgcatg acgttattta tgagatgggt ttttatgatt
     7441 agagtcccgc aattatacat ttaatacgcg atagaaaaca aaatatagcg cgcaaactag
     7501 gataaattat cgcgcgcggt gtcatctatg ttactagatc gggaattgcc aagctaattc
     7561 ttgaagacga aagggcctcg tgatacgcct atttttatag gttaatgtca tgataataat
     7621 ggtttcttag acgtcaggtg gcacttttcg gggaaatgtg cgcggaaccc ctatttgttt
     7681 atttttctaa atacattcaa atatgtatcc gctcatgaga caataaccct gataaatgct
     7741 tcaataatgg gaccgactcg cgctgtcagg agactagagc caagctgatc tcctttgccc
     7801 cggagatcac catggacgac tttctctatc tctacgatct aggaagaaag ttcgacggag
     7861 aaggtgacga taccatgttc accaccgata atgagaagat tagcctcttc aatttcagaa
     7921 agaatgctga cccacagatg gttagagagg cctacgcggc aggtctgatc aagacgatct
     7981 acccgagtaa taatctccag gagatcaaat accttcccaa gaaggttaaa gatgcagtca
     8041 aaagattcag gactaactgc atcaagaaca cagagaaaga tatatttctc aagatcagaa
     8101 gtactattcc agtatggacg attcaaggct tgcttcataa accaaggcaa gtaatagaga
     8161 ttggagtctc taagaaagta gttcctactg aatcaaaggc catggagtca aaaattcaga
     8221 tcgaggatct aacagaactc gccgtgaaga ctggcgaaca gttcatacag agtcttttac
     8281 gactcaatga caagaagaaa atcttcgtca acatggtgga gcacgacact ctcgtctact
     8341 ccaagaatat caaagataca gtctcagaag accaaagggc tattgagact tttcaacaaa
     8401 gggtaatatc gggaaacctc ctcggattcc attgcccagc tatctgtcac ttcatcaaaa
     8461 ggacagtaga aaaggaaggt ggcacctaca aatgccatca ttgcgataaa ggaaaggcta
     8521 tcgttcaaga tgcccctgcc gacagtggtc ccaaagatgg acccccaccc acgaggagca
     8581 tcgtggaaaa agaagacgtt ccaaccacgt cttcaaagca agtggattga tgtgatatct
     8641 ccactgacgt aagggatgac gcacaatccc actatccttc gcaagaccct tcctctatat
     8701 aaggaagttc atttcatttg gagaggactc cggtattttt acaacaatta ccacaacaaa
     8761 acaaacaaca aacaacatta caatttacta ttctagtcga aatggcccca ataagttcca
     8821 cgtggtctag gctcataagg tttgtggctg tggaaacctc cttagttcac atcggcgagc
     8881 ctattgatgc aacaatggac gtgggcttag cacgtaggga agggaagaca atacaagcct
     8941 atgagatcat cggcagtggc tctgctttag atctgtctgc ccaagtgtca aagaacgtac
     9001 ttacggtccg tgagctctta atgcccttga gccgtgagga gattaaaacg gtaagatgcc
     9061 ttggccttaa ttatcccgtc cacgccacag aagccaacgt ggccgtgccg aaattcccga
     9121 acctttttta caaacccgta acctccctca tcggaccagg tgggttgata accatccctt
     9181 cagttgtcca accacctaaa gagcaccaga gcgattacga agccgagttg gttatcgtca
     9241 tcggtaaagc cgccaaaaat gtcagtgaag atgaagctct ggactacgtg ttgggctaca
     9301 ccgcagccaa tgacatctca tttaggaaac atcagttggc cgtttctcaa tggtcattct
     9361 ccaagggttt tgatggcacg aatcccctgg gaccgtgcct ggtttctgct tcctctattc
     9421 cagatccaca ggatattccg atccaatgta aactcaacgg tggggtggtg caaaatggaa
     9481 acactcgtga tcagattttt aatgtcaaga aaacaatctc ttttttaagc caagggacta
     9541 cgttggagcc tggttccata atcctgacgg ggacgcccga cggagtgggc ttcgtaagaa
     9601 acccaccgct ttatttgaag gacggtgatg aagtaatgac ttggatcgga tcaggtatag
     9661 gaaccttagc caacactgtc cgagaggagc agacttgttt cgcttcagga gggcacgagt
     9721 aagcttggaa tggatcttcg atcccgatcg ttcaaacatt tggcaataaa gtttcttaag
     9781 attgaatcct gttgccggtc ttgcgacgat tatcatataa tttctgttga attacgttaa
     9841 gcatgtaata attaacatgt aatgcatgac gttatttatg agatgggttt ttatgattag
     9901 agtcccgcaa ttatacattt aatacgcgat agaaaacaaa atatagcgcg caaactagga
     9961 taaattatcg cgcgcggtgt catctatgtt actagatcgg gaattgccaa gctaattctt
    10021 gaagacgaaa gggcctcgtg atacgcctat ttttataggt taatgtcatg ataataatgg
    10081 tttcttagac gtcaggtggc acttttcggg gaaatgtgcg cggaacccct atttgtttat
    10141 ttttctaaat acattcaaat atgtatccgc tcatgagaca ataaccctga taaatgcttc
    10201 aataatggga ccgactcgcg ctgtcaggag actagagcca agctgatctc ctttgccccg
    10261 gagatcacca tggacgactt tctctatctc tacgatctag gaagaaagtt cgacggagaa
    10321 ggtgacgata ccatgttcac caccgataat gagaagatta gcctcttcaa tttcagaaag
    10381 aatgctgacc cacagatggt tagagaggcc tacgcggcag gtctgatcaa gacgatctac
    10441 ccgagtaata atctccagga gatcaaatac cttcccaaga aggttaaaga tgcagtcaaa
    10501 agattcagga ctaactgcat caagaacaca gagaaagata tatttctcaa gatcagaagt
    10561 actattccag tatggacgat tcaaggcttg cttcataaac caaggcaagt aatagagatt
    10621 ggagtctcta agaaagtagt tcctactgaa tcaaaggcca tggagtcaaa aattcagatc
    10681 gaggatctaa cagaactcgc cgtgaagact ggcgaacagt tcatacagag tcttttacga
    10741 ctcaatgaca agaagaaaat cttcgtcaac atggtggagc acgacactct cgtctactcc
    10801 aagaatatca aagatacagt ctcagaagac caaagggcta ttgagacttt tcaacaaagg
    10861 gtaatatcgg gaaacctcct cggattccat tgcccagcta tctgtcactt catcaaaagg
    10921 acagtagaaa aggaaggtgg cacctacaaa tgccatcatt gcgataaagg aaaggctatc
    10981 gttcaagatg cccctgccga cagtggtccc aaagatggac ccccacccac gaggagcatc
    11041 gtggaaaaag aagacgttcc aaccacgtct tcaaagcaag tggattgatg tgatatctcc
    11101 actgacgtaa gggatgacgc acaatcccac tatccttcgc aagacccttc ctctatataa
    11161 ggaagttcat ttcatttgga gaggactccg gtatttttac aacaattacc acaacaaaac
    11221 aaacaacaaa caacattaca atttactatt ctagtcgaaa tgagaattaa catctccctt
    11281 tcatcattat ttgaacgtct gtcaaagtta tccagcagat ccattgcaat cacctgtggt
    11341 gtcgtcttgg cctccgcaat cgcttttccg ataatccgta gggactatca gacttttttg
    11401 gaagtcgggc cgagttacgc tccgcagaat ttcagaggtt acatcatagt atgcgtgctt
    11461 tcactcttta ggcaggaaca aaaagggttg gctatctatg atcgactgcc cgaaaagcga
    11521 aggtggttgg cagatctccc attccgagaa ggtacgcgtc cttctatcac aagtcatatc
    11581 atccaaagac agaggactca gctggtagac caagaatttg caacccgaga actcattgat
    11641 aaagttatac ccagagttca ggctcgacac accgataaga cgtttctgtc aacctcaaag
    11701 ttcgaatttc atgccaaagc aatttttttg ctgcccagta ttcccatcaa tgatcccttg
    11761 aatatacctt cacatgatac tgtcagacga acaaaaaggg agatcgctca catgcacgat
    11821 taccacgact gcaccctgca cttggctctc gcagcccagg acggtaaaga agtacttaaa
    11881 aaagggtggg gccagagaca tcccctcgct ggccccggcg tgccgggacc tccaaccgaa
    11941 tggacgtttt tatatgcacc gcgtaacgag gaggaagcca gagtggtcga gatgatagtg
    12001 gaggccagta ttggttacat gacaaatgac cccgctggta aaattgtaga gaacgctaag
    12061 tgagcttgga atggatcttc gatcccgatc gttcaaacat ttggcaataa agtttcttaa
    12121 gattgaatcc tgttgccggt cttgcgacga ttatcatata atttctgttg aattacgtta
    12181 agcatgtaat aattaacatg taatgcatga cgttatttat gagatgggtt tttatgatta
    12241 gagtcccgca attatacatt taatacgcga tagaaaacaa aatatagcgc gcaaactagg
    12301 ataaattatc gcgcgcggtg tcatctatgt tactagatcg ggaattgcca agctaattct
    12361 tgaagacgaa agggcctcgt gatacgccta tttttatagg ttaatgtcat gataataatg
    12421 gtttcttaga cgtcaggtgg cacttttcgg ggaaatgtgc gcggaacccc tatttgttta
    12481 tttttctaaa tacattcaaa tatgtatccg ctcatgagac aataaccctg ataaatgctt
    12541 caataatggg accgactcgc gctgtcagga gactagagcc aagctgatct cctttgcccc
    12601 ggagatcacc atggacgact ttctctatct ctacgatcta ggaagaaagt tcgacggaga
    12661 aggtgacgat accatgttca ccaccgataa tgagaagatt agcctcttca atttcagaaa
    12721 gaatgctgac ccacagatgg ttagagaggc ctacgcggca ggtctgatca agacgatcta
    12781 cccgagtaat aatctccagg agatcaaata ccttcccaag aaggttaaag atgcagtcaa
    12841 aagattcagg actaactgca tcaagaacac agagaaagat atatttctca agatcagaag
    12901 tactattcca gtatggacga ttcaaggctt gcttcataaa ccaaggcaag taatagagat
    12961 tggagtctct aagaaagtag ttcctactga atcaaaggcc atggagtcaa aaattcagat
    13021 cgaggatcta acagaactcg ccgtgaagac tggcgaacag ttcatacaga gtcttttacg
    13081 actcaatgac aagaagaaaa tcttcgtcaa catggtggag cacgacactc tcgtctactc
    13141 caagaatatc aaagatacag tctcagaaga ccaaagggct attgagactt ttcaacaaag
    13201 ggtaatatcg ggaaacctcc tcggattcca ttgcccagct atctgtcact tcatcaaaag
    13261 gacagtagaa aaggaaggtg gcacctacaa atgccatcat tgcgataaag gaaaggctat
    13321 cgttcaagat gcccctgccg acagtggtcc caaagatgga cccccaccca cgaggagcat
    13381 cgtggaaaaa gaagacgttc caaccacgtc ttcaaagcaa gtggattgat gtgatatctc
    13441 cactgacgta agggatgacg cacaatccca ctatccttcg caagaccctt cctctatata
    13501 aggaagttca tttcatttgg agaggactcc ggtattttta caacaattac cacaacaaaa
    13561 caaacaacaa acaacattac aatttactat tctagtcgaa atggcatcct ttgaaaatag
    13621 tctgtccgtt ttgatcgtcg gggctggcct tgggggatta gcagccgcaa tagctcttag
    13681 gagacagggc catgtagtaa agatctatga tagttcctca ttcaaagctg aactgggtgc
    13741 tggccttgct gtacctccga atacgcttag aagccttcaa cagttaggtt gtaatacaga
    13801 gaatttgaac ggagtcgaca atctctgctt cacggccatg ggttacgacg gctccgtagg
    13861 tatgatgaat aacatgacag actacaggga ggcttatggc acatcctgga ttatggttca
    13921 tcgagtggat ttacataatg aacttatgcg tgtcgcactt gatccggggg ggctgggacc
    13981 accagcaaca ttacatttaa atcacagagt gaccttctgc gacgttgacg catgtacggt
    14041 aacttttacc aacgggacga cacaaagtgc cgacttgatc gtaggggctg acggcatacg
    14101 aagcaccata cgtagattcg tcttggagga agatgtaact gtgcctgcca gcgggatcgt
    14161 cggtttcaga tggctggtgc aagccgatgc cttagaccct taccctgagt tagattggat
    14221 tgttaagaag cctccactcg gtgctcgtct gatctctacg ccacagaatc cacagtccgg
    14281 cgtggggttg gctgaccgtc gtacaattat catctacgct tgtaggggtg gcacgatggt
    14341 taatgtgttg gctgtccacg acgacgaaag agatcagaat acggcagatt ggtcagtgcc
    14401 ggcttccaaa gatgatctct tccgtgtatt ccatgactac cacccaagat tcagacgttt
    14461 gctcgaactt gctcaagata tcaatctctg gcaaatgagg gtagttcccg tgcttaaaaa
    14521 atgggtgaac aagcgtgtct gtttattagg agatgccgcc catgcttctc tccccacgct
    14581 gggtcaaggg ttcggaatgg gactggagga cgccgtggca ctcggcacat tgttacccaa
    14641 aggaactacg gcttcacaga tcgaaacgag actggccgtt tacgagcaat tacgaaagga
    14701 tagggctgag ttcgtagcag cagaatccta cgaggaacag tatgtccctg agatgcgtgg
    14761 gctctatctt cgttccaaag aactccgaga tcgagtgatg ggatatgata ttaaagtgga
    14821 gtcagaaaag gttttggaga ctctgcttcg atcctctaat tctgcatgag cttggaatgg
    14881 atcttcgatc ccgatcgttc aaacatttgg caataaagtt tcttaagatt gaatcctgtt
    14941 gccggtcttg cgacgattat catataattt ctgttgaatt acgttaagca tgtaataatt
    15001 aacatgtaat gcatgacgtt atttatgaga tgggttttta tgattagagt cccgcaatta
    15061 tacatttaat acgcgataga aaacaaaata tagcgcgcaa actaggataa attatcgcgc
    15121 gcggtgtcat ctatgttact agatcgggaa ttgccaagct aattcttgaa gacgaaaggg
    15181 cctcgtgata cgcctatttt tataggttaa tgtcatgata ataatggttt cttagacgtc
    15241 aggtggcact tttcggggaa atgtgcgcgg aacccctatt tgtttatttt tctaaataca
    15301 ttcaaatatg tatccgctca tgagacaata accctgataa atgcttcaat aatgggaccg
    15361 actcgcgctg tcaggagact agagccaagc tgatctcctt tgccccggag atcaccatgg
    15421 acgactttct ctatctctac gatctaggaa gaaagttcga cggagaaggt gacgatacca
    15481 tgttcaccac cgataatgag aagattagcc tcttcaattt cagaaagaat gctgacccac
    15541 agatggttag agaggcctac gcggcaggtc tgatcaagac gatctacccg agtaataatc
    15601 tccaggagat caaatacctt cccaagaagg ttaaagatgc agtcaaaaga ttcaggacta
    15661 actgcatcaa gaacacagag aaagatatat ttctcaagat cagaagtact attccagtat
    15721 ggacgattca aggcttgctt cataaaccaa ggcaagtaat agagattgga gtctctaaga
    15781 aagtagttcc tactgaatca aaggccatgg agtcaaaaat tcagatcgag gatctaacag
    15841 aactcgccgt gaagactggc gaacagttca tacagagtct tttacgactc aatgacaaga
    15901 agaaaatctt cgtcaacatg gtggagcacg acactctcgt ctactccaag aatatcaaag
    15961 atacagtctc agaagaccaa agggctattg agacttttca acaaagggta atatcgggaa
    16021 acctcctcgg attccattgc ccagctatct gtcacttcat caaaaggaca gtagaaaagg
    16081 aaggtggcac ctacaaatgc catcattgcg ataaaggaaa ggctatcgtt caagatgccc
    16141 ctgccgacag tggtcccaaa gatggacccc cacccacgag gagcatcgtg gaaaaagaag
    16201 acgttccaac cacgtcttca aagcaagtgg attgatgtga tatctccact gacgtaaggg
    16261 atgacgcaca atcccactat ccttcgcaag acccttcctc tatataagga agttcatttc
    16321 atttggagag gactccggta tttttacaac aattaccaca acaaaacaaa caacaaacaa
    16381 cattacaatt tactattcta gtcgaaatgg tgagcaaggg cgaggagctg ttcaccgggg
    16441 tggtgcccat cctggtcgag ctggacggcg acgtaaacgg ccacaagttc agcgtgtccg
    16501 gcgagggcga gggcgatgcc acctacggca agctgaccct gaagttcatc tgcaccaccg
    16561 gcaagctgcc cgtgccctgg cccaccctcg tgaccaccct gacctacggc gtgcagtgct
    16621 tcagccgcta ccccgaccac atgaagcagc acgacttctt caagtccgcc atgcccgaag
    16681 gctacgtcca ggagcgcacc atcttcttca aggacgacgg caactacaag acccgcgccg
    16741 aggtgaagtt cgagggcgac accctggtga accgcatcga gctgaagggc atcgacttca
    16801 aggaggacgg caacatcctg gggcacaagc tggagtacaa ctacaacagc cacaacgtct
    16861 atatcatggc cgacaagcag aagaacggca tcaaggtgaa cttcaagatc cgccacaaca
    16921 tcgaggacgg cagcgtgcag ctcgccgacc actaccagca gaacaccccc atcggcgacg
    16981 gccccgtgct gctgcccgac aaccactacc tgagcaccca gtccgccctg agcaaagacc
    17041 ccaacgagaa gcgcgatcac atggtcctgc tggagttcgt gaccgccgcc gggatcactc
    17101 tcggcatgga cgagctgtac aaggacgagc tgtaagcttg gaatggatct tcgatcccga
    17161 tcgttcaaac atttggcaat aaagtttctt aagattgaat cctgttgccg gtcttgcgac
    17221 gattatcata taatttctgt tgaattacgt taagcatgta ataattaaca tgtaatgcat
    17281 gacgttattt atgagatggg tttttatgat tagagtcccg caattataca tttaatacgc
    17341 gatagaaaac aaaatatagc gcgcaaacta ggataaatta tcgcgcgcgg tgtcatctat
    17401 gttactagat cgggaattgc caagctaatt cttgaagacg aaagggcctc gtgatacgcc
    17461 tatttttata ggttaatgtc atgataataa tggtttctta gacgtcaggt ggcacttttc
    17521 ggggaaatgt gcgcggaacc cctatttgtt tatttttcta aatacattca aatatgtatc
    17581 cgctcatgag acaataaccc tgataaatgc ttcaataatg ggaccgactc gcgctgtcat
    17641 gagaccggat cctgacagga tatattggcg ggtaaaccta agagaaaaga gcgtttatta
    17701 gaataatcgg atatttaaaa gggcgtgaaa aggtttatcc gttcgtccat ttgtatgtgc
    17761 atgccaacca cagggttccc ctcgggatca aagtactttg atccaacccc tccgctgcta
    17821 tagtgcagtc ggcttctgac gttcagtgca gccgtcatct gaaaacgaca tgtcgcacaa
    17881 gtcctaagtt acgcgacagg ctgccgccct gcccttttcc tggcgttttc ttgtcgcgtg
    17941 ttttagtcgc ataaagtaga atacttgcga ctagaaccgg agacattacg ccatgaacaa
    18001 gagcgccgcc gctggcctgc tgggctatgc ccgcgtcagc accgacgacc aggacttgac
    18061 caaccaacgg gccgaactgc acgcggccgg ctgcaccaag ctgttttccg agaagatcac
    18121 cggcaccagg cgcgaccgcc cggagctggc caggatgctt gaccacctac gccctggcga
    18181 cgttgtgaca gtgaccaggc tagaccgcct ggcccgcagc acccgcgacc tactggacat
    18241 tgccgagcgc atccaggagg ccggcgcggg cctgcgtagc ctggcagagc cgtgggccga
    18301 caccaccacg ccggccggcc gcatggtgtt gaccgtgttc gccggcattg ccgagttcga
    18361 gcgttcccta atcatcgacc gcacccggag cgggcgcgag gccgccaagg cccgaggcgt
    18421 gaagtttggc ccccgcccta ccctcacccc ggcacagatc gcgcacgccc gcgagctgat
    18481 cgaccaggaa ggccgcaccg tgaaagaggc ggctgcactg cttggcgtgc atcgctcgac
    18541 cctgtaccgc gcacttgagc gcagcgagga agtgacgccc accgaggcca ggcggcgcgg
    18601 tgccttccgt gaggacgcat tgaccgaggc cgacgccctg gcggccgccg agaatgaacg
    18661 ccaagaggaa caagcatgaa accgcaccag gacggccagg acgaaccgtt tttcattacc
    18721 gaagagatcg aggcggagat gatcgcggcc gggtacgtgt tcgagccgcc cgcgcacctc
    18781 tcaaccgtgc ggctgcatga aatcctggcc ggtttgtctg atgccaagct ggcggcctgg
    18841 ccggccagct tggccgctga agaaaccgag cgccgccgtc taaaaaggtg atgtgtattt
    18901 gagtaaaaca gcttgcgtca tgcggtcgct gcgtatatga tgcgatgagt aaataaacaa
    18961 atacgcaagg ggaacgcatg aaggttatcg ctgtacttaa ccagaaaggc gggtcaggca
    19021 agacgaccat cgcaacccat ctagcccgcg ccctgcaact cgccggggcc gatgttctgt
    19081 tagtcgattc cgatccccag ggcagtgccc gcgattgggc ggccgtgcgg gaagatcaac
    19141 cgctaaccgt tgtcggcatc gaccgcccga cgattgaccg cgacgtgaag gccatcggcc
    19201 ggcgcgactt cgtagtgatc gacggagcgc cccaggcggc ggacttggct gtgtccgcga
    19261 tcaaggcagc cgacttcgtg ctgattccgg tgcagccaag cccttacgac atatgggcca
    19321 ccgccgacct ggtggagctg gttaagcagc gcattgaggt cacggatgga aggctacaag
    19381 cggcctttgt cgtgtcgcgg gcgatcaaag gcacgcgcat cggcggtgag gttgccgagg
    19441 cgctggccgg gtacgagctg cccattcttg agtcccgtat cacgcagcgc gtgagctacc
    19501 caggcactgc cgccgccggc acaaccgttc ttgaatcaga acccgagggc gacgctgccc
    19561 gcgaggtcca ggcgctggcc gctgaaatta aatcaaaact catttgagtt aatgaggtaa
    19621 agagaaaatg agcaaaagca caaacacgct aagtgccggc cgtccgagcg cacgcagcag
    19681 caaggctgca acgttggcca gcctggcaga cacgccagcc atgaagcggg tcaactttca
    19741 gttgccggcg gaggatcaca ccaagctgaa gatgtacgcg gtacgccaag gcaagaccat
    19801 taccgagctg ctatctgaat acatcgcgca gctaccagag taaatgagca aatgaataaa
    19861 tgagtagatg aattttagcg gctaaaggag gcggcatgga aaatcaagaa caaccaggca
    19921 ccgacgccgt ggaatgcccc atgtgtggag gaacgggcgg ttggccaggc gtaagcggct
    19981 gggttgcctg ccggccctgc aatggcactg gaacccccaa gcccgaggaa tcggcgtgag
    20041 cggtcgcaaa ccatccggcc cggtacaaat cggcgcggcg ctgggtgatg acctggtgga
    20101 gaagttgaag gccgcgcagg ccgcccagcg gcaacgcatc gaggcagaag cacgccccgg
    20161 tgaatcgtgg caagcggccg ctgatcgaat ccgcaaagaa tcccggcaac cgccggcagc
    20221 cggtgcgccg tcgattagga agccgcccaa gggcgacgag caaccagatt ttttcgttcc
    20281 gatgctctat gacgtgggca cccgcgatag tcgcagcatc atggacgtgg ccgttttccg
    20341 tctgtcgaag cgtgaccgac gagctggcga ggtgatccgc tacgagcttc cagacgggca
    20401 cgtagaggtt tccgcagggc cggccggcat ggccagtgtg tgggattacg acctggtact
    20461 gatggcggtt tcccatctaa ccgaatccat gaaccgatac cgggaaggga agggagacaa
    20521 gcccggccgc gtgttccgtc cacacgttgc ggacgtactc aagttctgcc ggcgagccga
    20581 tggcggaaag cagaaagacg acctggtaga aacctgcatt cggttaaaca ccacgcacgt
    20641 tgccatgcag cgtacgaaga aggccaagaa cggccgcctg gtgacggtat ccgagggtga
    20701 agccttgatt agccgctaca agatcgtaaa gagcgaaacc gggcggccgg agtacatcga
    20761 gatcgagcta gctgattgga tgtaccgcga gatcacagaa ggcaagaacc cggacgtgct
    20821 gacggttcac cccgattact ttttgatcga tcccggcatc ggccgttttc tctaccgcct
    20881 ggcacgccgc gccgcaggca aggcagaagc cagatggttg ttcaagacga tctacgaacg
    20941 cagtggcagc gccggagagt tcaagaagtt ctgtttcacc gtgcgcaagc tgatcgggtc
    21001 aaatgacctg ccggagtacg atttgaagga ggaggcgggg caggctggcc cgatcctagt
    21061 catgcgctac cgcaacctga tcgagggcga agcatccgcc ggttcctaat gtacggagca
    21121 gatgctaggg caaattgccc tagcagggga aaaaggtcga aaaggactct ttcctgtgga
    21181 tagcacgtac attgggaacc caaagccgta cattgggaac cggaacccgt acattgggaa
    21241 cccaaagccg tacattggga accggtcaca catgtaagtg actgatataa aagagaaaaa
    21301 aggcgatttt tccgcctaaa actctttaaa acttattaaa actcttaaaa cccgcctggc
    21361 ctgtgcataa ctgtctggcc agcgcacagc cgaagagctg caaaaagcgc ctacccttcg
    21421 gtcgctgcgc tccctacgcc ccgccgcttc gcgtcggcct atcgcggccg ctggccgctc
    21481 aaaaatggct ggcctacggc caggcaatct accagggcgc ggacaagccg cgccgtcgcc
    21541 actcgaccgc cggcgcccac atcaaggcac cctgcctcgc gcgtttcggt gatgacggtg
    21601 aaaacctctg acacatgcag ctcccggtga cggtcacagc ttgtctgtaa gcggatgccg
    21661 ggagcagaca agcccgtcag ggcgcgtcag cgggtgttgg cgggtgtcgg ggcgcagcca
    21721 tgacccagtc acgtagcgat agcggagtgt atactggctt aactatgcgg catcagagca
    21781 gattgtactg agagtgcacc atatgcggtg tgaaataccg cacagatgcg taaggagaaa
    21841 ataccgcatc aggcgctctt ccgcttcctc gctcactgac tcgctgcgct cggtcgttcg
    21901 gctgcggcga gcggtatcag ctcactcaaa ggcggtaata cggttatcca cagaatcagg
    21961 ggataacgca ggaaagaaca tgtgagcaaa aggccagcaa aaggccagga accgtaaaaa
    22021 ggccgcgttg ctggcgtttt tccataggct ccgcccccct gacgagcatc acaaaaatcg
    22081 acgctcaagt cagaggtggc gaaacccgac aggactataa agataccagg cgtttccccc
    22141 tggaagctcc ctcgtgcgct ctcctgttcc gaccctgccg cttaccggat acctgtccgc
    22201 ctttctccct tcgggaagcg tggcgctttc tcatagctca cgctgtaggt atctcagttc
    22261 ggtgtaggtc gttcgctcca agctgggctg tgtgcacgaa ccccccgttc agcccgaccg
    22321 ctgcgcctta tccggtaact atcgtcttga gtccaacccg gtaagacacg acttatcgcc
    22381 actggcagca gccactggta acaggattag cagagcgagg tatgtaggcg gtgctacaga
    22441 gttcttgaag tggtggccta actacggcta cactagaagg acagtatttg gtatctgcgc
    22501 tctgctgaag ccagttacct tcggaaaaag agttggtagc tcttgatccg gcaaacaaac
    22561 caccgctggt agcggtggtt tttttgtttg caagcagcag attacgcgca gaaaaaaagg
    22621 atctcaagaa gatcctttga tcttttctac ggggtctgac gctcagtgga acgaaaactc
    22681 acgttaaggg attttggtca tgcattctag gtgattattt gccgactacc ttggtgatct
    22741 cgcctttcac gtagtggaca aattcttcca actgatctgc gcgcgaggcc aagcgatctt
    22801 cttcttgtcc aagataagcc tgtctagctt caagtatgac gggctgatac tgggccggca
    22861 ggcgctccat tgcccagtcg gcagcgacat ccttcggcgc gattttgccg gttactgcgc
    22921 tgtaccaaat gcgggacaac gtaagcacta catttcgctc atcaccagcc cagtcgggcg
    22981 gcgagttcca tagcgttaag gtttcattta gcgcctcaaa tagatcctgt tcaggaaccg
    23041 gatcaaagag ttcctccgcc gctggaccta ccaaggcaac gctatgttct cttgcttttg
    23101 tcagcaagat agccagatca atgtcgatcg tggctggctc gaagatacct gcaagaatgt
    23161 cattgcgctg ccattctcca aattgcagtt cgcgcttagc tggataacgc cacggaatga
    23221 tgtcgtcgtg cacaacaatg gtgacttcta cagcgcggag aatctcgctc tctccagggg
    23281 aagccgaagt ttccaaaagg tcgttgatca aagctcgccg cgttgtttca tcaagcctta
    23341 cggtcaccgt aaccagcaaa tcaatatcac tgtgtggctt caggccgcca tccactgcgg
    23401 agccgtacaa atgtacggcc agcaacgtcg gttcgagatg gcgctcgatg acgccaacta
    23461 cctctgatag ttgagtcgat acttcggcga tcaccgcttc cctcataatg tttaactttg
    23521 ttttagggcg actgccctgc tgcgtaacat cgttgctgct ccataacatc aaacatcgac
    23581 ccacggcgta acgcgcttgc tgcttggatg cccgaggcat agactgtacc ccaaaaaaac
    23641 agtcataaca agccatgaaa accgccactg cgccgttacc accgctgcgt tcggtcaagg
    23701 ttctggacca gttgcgtgag cgcatacgct acttgcatta cagcttacga accgaacagg
    23761 cttatgtcca ctgggttcgt gccttcatcc gtttccacgg tgtgcgtcac ccggcaacct
    23821 tgggtagcag cgaagtcgag gcatttctgt cctggctgga acagaactta ttatttcctt
    23881 cctcttttct acagtattta aagatacccc aagaagctaa ttataacaag acgaactcca
    23941 attcactgtt ccttgcattc taaaacctta aataccagaa aacagctttt tcaaagttgt
    24001 tttcaaagtt ggcgtataac atagtatcga cggagccgat tttgaaaccg cggtgatcac
    24061 aggcagcaac gctctgtcat cgttacaatc aacatgctac cctccgcgag atcatccgtg
    24121 tttcaaaccc ggcagcttag ttgccgttct tccgaatagc atcggtaaca tgagcaaagt
    24181 ctgccgcctt acaacggctc tcccgctgac gccgtcccgg actgatgggc tgcctgtatc
    24241 gagtggtgat tttgtgccga gctgccggtc ggggagctgt tggctggctg gtggcaggat
    24301 atattgtggt gtaaacataa cggatccggt ctca
//
