LOCUS       sequence-462729-       20782 bp    DNA     circular SYN 15-DEC-2025
DEFINITION  Expresses ePE6d — engineered SpCas9 nickase (nCas9), RNA chaperone 
            nucleocapsid (NC) protein, with T128N/N200C/V223Y variant of 
            MMLV-Delta-RNaseH — for gene editing in rice.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      synthetic DNA construct
  ORGANISM  synthetic DNA construct
REFERENCE   1  (bases 1 to 20782)
  AUTHORS   Xu R, Ma C, Sheng J, Zhu J, Wang D, Liu X, Wang Q, Li J, Qin R, Wei 
            P
  TITLE     Engineering PE6 prime editors to efficiently insert tags in rice.
  JOURNAL   Plant Biotechnol J. 2024 Sep 27. doi: 10.1111/pbi.14456.
  PUBMED    39331467
REFERENCE   2  (bases 1 to 20782)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Plant 
            Biotechnol J. 2024 Sep 27. doi: 10.1111/pbi.14456."
COMMENT     Sequence Label: ePE6d
FEATURES             Location/Qualifiers
     source          1..20782
                     /mol_type="other DNA"
                     /organism="synthetic DNA construct"
     misc_feature    21..45
                     /label=RB T-DNA repeat
                     /note="right border repeat from nopaline C58 T-DNA"
     CDS             complement(129..662)
                     /codon_start=1
                     /gene="aacC1"
                     /product="gentamycin acetyltransferase"
                     /label=GmR
                     /note="confers resistance to gentamycin"
                     /translation="MLWSSNDVTQQGSRPKTKLGGSSMGIIRTCRLGPDQVKSMRAALD
                     LFGREFGDVATYSQHQPDSDYLGNLLRSKTFIALAAFDQEAVVGALAAYVLPKFEQPRS
                     EIYIYDLAVSGEHRRQGIATALINLLKHEANALGAYVIYVQADYGDDPAVALYTKLGIR
                     EEVMHFDIDPSTAT"
     promoter        complement(join(832..837,838..854,855..860))
                     /gene="intI1 (promoter lies within the coding sequence)"
                     /label=Pc promoter
                     /note="class 1 integron promoter"
     primer_bind     1041..1063
                     /label=M13/pUC Forward
                     /note="In lacZ gene"
     primer_bind     1055..1072
                     /label=M13 Forward
                     /note="In lacZ gene. Also called M13-F20 or M13 (-21) 
                     Forward"
     primer_bind     1056..1072
                     /label=M13 fwd
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     CDS             2431..3222
                     /codon_start=1
                     /gene="aadA"
                     /product="aminoglycoside adenylyltransferase (Murphy, 
                     1985)"
                     /label=SmR
                     /note="confers resistance to spectinomycin and 
                     streptomycin"
                     /translation="MGEAVIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKPH
                     SDIDLLVTVTVRLDETTRRALINDLLETSASPGESEILRAVEVTIVVHDDIIPWRYPAK
                     RELQFGEWQRNDILAGIFEPATIDIDLAILLTKAREHSVALVGPAAEELFDPVPEQDLF
                     EALNETLTLWNSPPDWAGDERNVVLTLSRIWYSAVTGKIAPKDVAADWAMERLPAQYQP
                     VILEARQAYLGQEEDRLASRADQLEEFVHYVKGEITKVVGK"
     ncRNA           3416..3483
                     /product="hepatitis delta virus self-cleaving ribozyme 
                     (Ferre-D'Amare and Scott, 2010)"
                     /label=HDV ribozyme
                     /ncRNA_class="ribozyme"
     terminator      3514..3762
                     /label=HSP terminator
                     /note="efficient transcription terminator from the 
                     Arabidopsis thaliana heat shock protein 18.2 gene (Nagaya 
                     et al., 2010)"
     regulatory      5755..5764
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
     CDS             5767..5787
                     /codon_start=1
                     /product="nuclear localization signal of SV40 (simian virus
                     40) large T antigen"
                     /label=SV40 NLS
                     /translation="PKKKRKV"
     CDS             10162..10182
                     /codon_start=1
                     /product="nuclear localization signal of SV40 (simian virus
                     40) large T antigen"
                     /label=SV40 NLS
                     /translation="PKKKRKV"
     CDS             11752..11772
                     /codon_start=1
                     /product="nuclear localization signal of SV40 (simian virus
                     40) large T antigen"
                     /label=SV40 NLS
                     /translation="PKKKRKV"
     CDS             11782..11808
                     /codon_start=1
                     /product="nuclear localization signal of human c-Myc 
                     proto-oncogene (Dang and Lee, 1988)"
                     /label=c-myc NLS
                     /translation="PAAKRVKLD"
     protein_bind    complement(11834..11858)
                     /gene="mutant version of attB"
                     /label=attB2
                     /bound_moiety="BP Clonase(TM)"
                     /note="recombination site for the Gateway(R) BP reaction"
     regulatory      11871..11880
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
     primer_bind     complement(12157..12173)
                     /label=M13 rev
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     primer_bind     complement(12157..12173)
                     /label=M13 Reverse
                     /note="In lacZ gene. Also called M13-rev"
     primer_bind     complement(12170..12192)
                     /label=M13/pUC Reverse
                     /note="In lacZ gene"
     protein_bind    12181..12197
                     /label=lac operator
                     /bound_moiety="lac repressor encoded by lacI"
                     /note="The lac repressor binds to the lac operator to 
                     inhibit transcription in E. coli. This inhibition can be 
                     relieved by adding lactose or 
                     isopropyl-beta-D-thiogalactopyranoside (IPTG)."
     promoter        complement(join(12205..12211,12212..12229,12230..12235))
                     /label=lac promoter
                     /note="promoter for the E. coli lac operon"
     protein_bind    12250..12271
                     /label=CAP binding site
                     /bound_moiety="E. coli catabolite activator protein"
                     /note="CAP binding activates transcription in the presence 
                     of cAMP."
     promoter        12462..13138
                     /label=CaMV 35S promoter (enhanced)
                     /note="cauliflower mosaic virus 35S promoter with a 
                     duplicated enhancer region"
     primer_bind     13075..13095
                     /label=35S promoter
                     /note="CaMV 35S promoter, forward primer"
     CDS             13205..14230
                     /codon_start=1
                     /product="hygromycin B phosphotransferase"
                     /label=HygR
                     /note="confers resistance to hygromycin"
                     /translation="MKKPELTATSVEKFLIEKFDSVSDLMQLSEGEESRAFSFDVGGRG
                     YVLRVNSCADGFYKDRYVYRHFASAALPIPEVLDIGEFSESLTYCISRRSQGVTLQDLP
                     ETELPAVLQPVAEAMDAIAAADLSQTSGFGPFGPQGIGQYTTWRDFICAIADPHVYHWQ
                     TVMDDTVSASVAQALDELMLWAEDCPEVRHLVHADFGSNNVLTDNGRITAVIDWSEAMF
                     GDSQYEVANIFFWRPWLACMEQQTRYFERRHPELAGSPRLRAYMLRIGLDQLYQSLVDG
                     NFDDAAWAQGRCDAIVRSGAGTVGRTQIARRSAAVWTDGCVEVLADSGNRRPSTRPRAK
                     K"
     polyA_signal    14271..14445
                     /label=CaMV poly(A) signal
                     /note="cauliflower mosaic virus polyadenylation signal"
     misc_feature    14523..14547
                     /label=LB T-DNA repeat
                     /note="left border repeat from nopaline C58 T-DNA"
     CDS             14972..15766
                     /codon_start=1
                     /gene="aphA-3"
                     /product="aminoglycoside phosphotransferase"
                     /label=KanR
                     /note="confers resistance to kanamycin"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLKM
                     TDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEYED
                     EQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWEEDT
                     PFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKWYDIA
                     FCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     rep_origin      15853..16441
                     /direction=RIGHT
                     /label=ori
                     /note="high-copy-number ColE1/pMB1/pBR322/pUC origin of 
                     replication"
     primer_bind     16342..16361
                     /label=pBR322ori-F
                     /note="pBR322 origin, forward primer"
     primer_bind     16595..16612
                     /label=L4440
                     /note="L4440 vector, forward primer"
     misc_feature    16627..16767
                     /label=bom
                     /note="basis of mobility region from pBR322"
     primer_bind     complement(16693..16712)
                     /label=pRS-marker
                     /note="pRS vectors, use to sequence yeast selectable 
                     marker"
     primer_bind     16853..16875
                     /label=pGEX 3'
                     /note="pGEX vectors, reverse primer"
     rep_origin      17111..17305
                     /label=pVS1 oriV
                     /note="origin of replication for the Pseudomonas plasmid 
                     pVS1 (Heeb et al., 2000)"
     CDS             complement(17371..18444)
                     /codon_start=1
                     /product="replication protein from the Pseudomonas plasmid 
                     pVS1 (Heeb et al., 2000)"
                     /label=pVS1 RepA
                     /translation="MSGRKPSGPVQIGAALGDDLVEKLKAAQAAQRQRIEAEARPGESW
                     QAAADRIRKESRQPPAAGAPSIRKPPKGDEQPDFFVPMLYDVGTRDSRSIMDVAVFRLS
                     KRDRRAGEVIRYELPDGHVEVSAGPAGMASVWDYDLVLMAVSHLTESMNRYREGKGDKP
                     GRVFRPHVADVLKFCRRADGGKQKDDLVETCIRLNTTHVAMQRTKKAKNGRLVTVSEGE
                     ALISRYKIVKSETGRPEYIEIELADWMYREITEGKNPDVLTVHPDYFLIDPGIGRFLYR
                     LARRAAGKAEARWLFKTIYERSGSAGEFKKFCFTVRKLIGSNDLPEYDLKEEAGQAGPI
                     LVMRYRNLIEGEASAGS"
     CDS             complement(18873..19502)
                     /codon_start=1
                     /product="stability protein from the Pseudomonas plasmid 
                     pVS1 (Heeb et al., 2000)"
                     /label=pVS1 StaA
                     /translation="MKVIAVLNQKGGSGKTTIATHLARALQLAGADVLLVDSDPQGSAR
                     DWAAVREDQPLTVVGIDRPTIDRDVKAIGRRDFVVIDGAPQAADLAVSAIKAADFVLIP
                     VQPSPYDIWATADLVELVKQRIEVTDGRLQAAFVVSRAIKGTRIGGEVAEALAGYELPI
                     LESRITQRVSYPGTAAAGTTVLESEPEGDAAREVQALAAEIKSKLI"
ORIGIN
        1 taaacgctct tttctcttag gtttacccgc caatatatcc tgtcaaacac tgatagttta
       61 aaccggcgtt gtgacaattt accgaacaac tccgcggccg ggaagccgat ctcggcttga
      121 acgaattgtt aggtggcggt acttgggtcg atatcaaagt gcatcacttc ttcccgtatg
      181 cccaactttg tatagagagc cactgcggga tcgtcaccgt aatctgcttg cacgtagatc
      241 acataagcac caagcgcgtt ggcctcatgc ttgaggagat tgatgagcgc ggtggcaatg
      301 ccctgcctcc ggtgctcgcc ggagactgcg agatcataga tatagatctc actacgcggc
      361 tgctcaaact tgggcagaac gtaagccgcg agagcgccaa caaccgcttc ttggtcgaag
      421 gcagcaagcg cgatgaatgt cttactacgg agcaagttcc cgaggtaatc ggagtccggc
      481 tgatgttggg agtaggtggc tacgtctccg aactcacgac cgaaaagatc aagagcagcc
      541 cgcatggatt tgacttggtc agggccgagc ctacatgtgc gaatgatgcc catacttgag
      601 ccacctaact ttgttttagg gcgactgccc tgctgcgtaa catcgttgct gctccataac
      661 atcaaacatc gacccacggc gtaacgcgct tgctgcttgg atgcccgagg catagactgt
      721 acaaaaaaac agtcataaca agccatgaaa accgccactg cgccgttacc accgctgcgt
      781 tcggtcaagg ttctggacca gttgcgtgag cgcatacgct acttgcatta cagtttacga
      841 accgaacagg cttatgtcaa ctggtttaaa ctgaaggcgg gaaacgacaa tctgatccaa
      901 gctcaagctg ctctagcatt cgccattcag gctgcgcaac tgttgggaag ggcgatcggt
      961 gcgggcctct tcgctattac gccagctggc gaaaggggga tgtgctgcaa ggcgattaag
     1021 ttgggtaacg ccagggtttt cccagtcacg acgttgtaaa acgacggcca gtgccaagct
     1081 tatggagtca aagattcaaa tagaggacct aacagaactc gccgtaaaga ctggcgaaca
     1141 gttcatacag agtctcttac gactcaatga caagaagaaa atcttcgtca acatggtgga
     1201 gcacgacaca cttgtctact ccaaaaatat caaagataca gtctcagaag accaaagggc
     1261 aattgagact tttcaacaaa gggtaatatc cggaaacctc ctcggattcc attgcccagc
     1321 tatctgtcac tttattgtga agatagtgga aaaggaaggt ggctcctaca aatgccatca
     1381 ttgcgataaa ggaaaggcca tcgttgaaga tgcctctgcc gacagtggtc ccaaagatgg
     1441 acccccaccc acgaggagca tcgtggaaaa agaagacgtt ccaaccacgt cttcaaagca
     1501 agtggattga tgtgattggc agacatactg tcccacaaat gaagatggaa tctgtaaaag
     1561 aaaacgcgtg aaataatgcg tctgacaaag gttaggtcgg ctgcctttaa tcaataccaa
     1621 agtggtccct accacgatgg aaaaactgtg cagtcggttt ggctttttct gacgaacaaa
     1681 taagattcgt ggccgacagg tgggggtcca ccatgtgaag gcatcttcag actccaataa
     1741 tggagcaatg acgtaagggc ttacgaaata agtaagggta gtttgggaaa tgtccactca
     1801 cccgtcagtc tataaatact tagcccctcc ctcattgtta agggagcaaa atctcagaga
     1861 gatagtccta gagagagaaa gagagcaagt agcctagaag tagtcaaggc ggcgaagtat
     1921 tcaggcacgt ggccaggaag aagaaaagcc aagacgacga aaacaggtaa gagctaagca
     1981 tctagaaagt tgaaaacaat cttcaaaagt cccacatcgc ttagataaga aaacgaagct
     2041 gagtttatat acagctagag tcgaagtagt gattgaacaa agcaccagtg gtctagtggt
     2101 agaatagtac cctgccacgg tacagacccg ggttcgattc ccggctggtg caagagacca
     2161 acccagtgga cataagcctg ttcggttcgt aagctgtaat gcaagtagcg tatgcgctca
     2221 cgcaactggt ccagaacctt gaccgaacgc agcggtggta acggcgcagt ggcggttttc
     2281 atggcttgtt atgactgttt ttttggggta cagtctatgc ctcgggcatc caagcagcaa
     2341 gcgcgttacg ccgtgggtcg atgtttgatg ttatggagca gcaacgatgt tacgcagcag
     2401 ggcagtcgcc ctaaaacaaa gttaaacatc atgggggaag cggtgatcgc cgaagtatcg
     2461 actcaactat cagaggtagt tggcgtcatc gagcgccatc tcgaaccgac gttgctggcc
     2521 gtacatttgt acggctccgc agtggatggc ggcctgaagc cacacagtga tattgatttg
     2581 ctggttacgg tgaccgtaag gcttgatgaa acaacgcggc gagctttgat caacgacctt
     2641 ttggaaactt cggcttcccc tggagagagc gagattctcc gcgctgtaga agtcaccatt
     2701 gttgtgcacg acgacatcat tccgtggcgt tatccagcta agcgcgaact gcaatttgga
     2761 gaatggcagc gcaatgacat tcttgcaggt atcttcgagc cagccacgat cgacattgat
     2821 ctggctatct tgctgacaaa agcaagagaa catagcgttg ccttggtagg tccagcggcg
     2881 gaggaactct ttgatccggt tcctgaacag gatctatttg aggcgctaaa tgaaacctta
     2941 acgctatgga actcgccgcc cgactgggct ggcgatgagc gaaatgtagt gcttacgttg
     3001 tcccgcattt ggtacagcgc agtaaccggc aaaatcgcgc cgaaggatgt cgctgccgac
     3061 tgggcaatgg agcgcctgcc ggcccagtat cagcccgtca tacttgaagc tagacaggct
     3121 tatcttggac aagaagaaga tcgcttggcc tcgcgcgcag atcagttgga agaatttgtc
     3181 cactacgtga aaggcgagat caccaaggta gtcggcaaat aatgtctagc tagaaattcg
     3241 ttcaagccga cgccgcttcg cggcgcggct taactcaagc gttagatgca ctaagcacat
     3301 aattgctcac agccaaacta tcaggtcaag tctgctttta ttatttttaa gcgtgcataa
     3361 taagccggtc tcattgacgc ggttctatct agttacgcgt taaaccaact agaaaggccg
     3421 gcatggtccc agcctcctcg ctggcgccgg ctgggcaaca tgcttcggca tggcgaatgg
     3481 gacttttttt tgatatctcc ggggctaatt gaatatgaag atgaagatga aatatttggt
     3541 gtgtcaaata aaaagctggt gtgcttaagt ttgtgttttt ttcttggctt gttgtgttat
     3601 gaatttgtgg ctttttctaa tattaaatga atgtaagatc tcattataat gaataaacaa
     3661 atgtttctat aatccattgt gaatgttttg ttggatctct tctgcagcat ataactactg
     3721 tatgtgctat ggtatggact atggaatatg attaaagata agaagctttg cagcgtgacc
     3781 cggtcgtgcc cctctctaga gataatgagc attgcatgtc taagttataa aaaattacca
     3841 catatttttt ttgtcacact tgtttgaagt gcagtttatc tatctttata catatattta
     3901 aactttactc tacgaataat ataatctata gtactacaat aatatcagtg ttttagagaa
     3961 tcatataaat gaacagttag acatggtcta aaggacaatt gagtattttg acaacaggac
     4021 tctacagttt tatcttttta gtgtgcatgt gttctccttt ttttttgcaa atagcttcac
     4081 ctatataata cttcatccat tttattagta catccattta gggtttaggg ttaatggttt
     4141 ttatagacta atttttttag tacatctatt ttattctatt ttagcctcta aattaagaaa
     4201 actaaaactc tattttagtt tttttattta ataatttaga tataaaatag aataaaataa
     4261 agtgactaaa aattaaacaa atacccttta agaaattaaa aaaactaagg aaacattttt
     4321 cttgtttcga gtagataatg ccagcctgtt aaacgccgtc gacgagtcta acggacacca
     4381 accagcgaac cagcagcgtc gcgtcgggcc aagcgaagca gacggcacgg catctctgtc
     4441 gctgcctctg gacccctctc gagagttccg ctccaccgtt ggacttgctc cgctgtcggc
     4501 atccagaaat tgcgtggcgg agcggcagac gtgagccggc acggcaggcg gcctcctcct
     4561 cctctcacgg caccggcagc tacgggggat tcctttccca ccgctccttc gctttccctt
     4621 cctcgcccgc cgtaataaat agacaccccc tccacaccct ctttccccaa cctcgtgttg
     4681 ttcggagcgc acacacacac aaccagatct cccccaaatc cacccgtcgg cacctccgct
     4741 tcaaggtacg ccgctcgtcc tccccccccc ccctctctac cttctctaga tcggcgttcc
     4801 ggtccatggt tagggcccgg tagttctact tctgttcatg tttgtgttag atccgtgttt
     4861 gtgttagatc cgtgctgcta gcgttcgtac acggatgcga cctgtacgtc agacacgttc
     4921 tgattgctaa cttgccagtg tttctctttg gggaatcctg ggatggctct agccgttccg
     4981 cagacgggat cgatttcatg attttttttg tttcgttgca tagggtttgg tttgcccttt
     5041 tcctttattt caatatatgc cgtgcacttg tttgtcgggt catcttttca tgcttttttt
     5101 tgtcttggtt gtgatgatgt ggtctggttg ggcggtcgtt ctagatcgga gtagaattct
     5161 gtttcaaact acctggtgga tttattaatt ttggatctgt atgtgtgtgc catacatatt
     5221 catagttacg aattgaagat gatggatgga aatatcgatc taggataggt atacatgttg
     5281 atgcgggttt tactgatgca tatacagaga tgctttttgt tcgcttggtt gtgatgatgt
     5341 ggtgtggttg ggcggtcgtt cattcgttct agatcggagt agaatactgt ttcaaactac
     5401 ctggtgtatt tattaatttt ggaactgtat gtgtgtgtca tacatcttca tagttacgag
     5461 tttaagatgg atggaaatat cgatctagga taggtataca tgttgatgtg ggttttactg
     5521 atgcatatac atgatggcat atgcagcatc tattcatatg ctctaacctt gagtacctat
     5581 ctattataat aaacaagtat gttttataat tattttgatc ttgatatact tggatgatgg
     5641 catatgcagc agctatatgt ggattttttt agccctgcct tcatacgcta tttatttgct
     5701 tggtactgtt tcttttgtcg atgctcaccc tgttgtttgg tgttacttct gcaggccacc
     5761 atggccccaa agaagaagcg caaggtcgac aagaagtact ccatcggcct cgacatcggc
     5821 accaattctg ttggctgggc cgtgatcacc gacgagtaca aggtgccgtc caagaagttc
     5881 aaggtcctcg gcaacaccga ccgccactcc atcaagaaga atctcatcgg cgccctgctg
     5941 ttcgactctg gcgagacagc cgaggctaca aggctcaaga ggaccgctag acgcaggtac
     6001 accaggcgca agaaccgcat ctgctacctc caagagatct tctccaacga gatggccaag
     6061 gtggacgaca gcttcttcca caggctcgag gagagcttcc tcgtcgagga ggacaagaag
     6121 cacgagcgcc atccgatctt cggcaacatc gtggatgagg tggcctacca cgagaagtac
     6181 ccgaccatct accacctccg caagaagctc gtcgactcca ccgataaggc cgacctcagg
     6241 ctcatctacc tcgccctcgc ccacatgatc aagttcaggg gccacttcct catcgagggc
     6301 gacctcaacc cggacaactc cgatgtggac aagctgttca tccagctcgt gcagacctac
     6361 aaccagctgt tcgaggagaa cccgatcaac gcctctggcg ttgacgccaa ggctattctc
     6421 tctgccaggc tctctaagtc ccgcaagctc gagaatctga tcgcccaact tccgggcgag
     6481 aagaagaatg gcctcttcgg caacctgatc gccctctctc ttggcctcac cccgaacttc
     6541 aagtccaact tcgacctcgc cgaggacgcc aagctccagc tttccaagga cacctacgac
     6601 gacgacctcg acaatctcct cgcccagatt ggcgatcagt acgccgatct gttcctcgcc
     6661 gccaagaatc tctccgacgc catcctcctc agcgacatcc tcagggtgaa caccgagatc
     6721 accaaggccc cactctccgc ctccatgatc aagaggtacg acgagcacca ccaggacctc
     6781 acactcctca aggccctcgt gagacagcag ctcccagaga agtacaagga gatcttcttc
     6841 gaccagtcca agaacggcta cgccggctac atcgatggcg gcgcttctca agaggagttc
     6901 tacaagttca tcaagccgat cctcgagaag atggacggca ccgaggagct gctcgtgaag
     6961 ctcaagagag aggacctcct ccgcaagcag cgcaccttcg ataatggctc catcccgcac
     7021 cagatccacc tcggcgagct tcatgctatc ctccgcaggc aagaggactt ctacccgttc
     7081 ctcaaggaca accgcgagaa gattgagaag atcctcacct tccgcatccc gtactacgtg
     7141 ggcccgctcg ccaggggcaa ctccaggttc gcctggatga ccagaaagtc cgaggagaca
     7201 atcaccccct ggaacttcga ggaggtggtg gataagggcg cctctgccca gtctttcatc
     7261 gagcgcatga ccaacttcga caagaacctc ccgaacgaga aggtgctccc gaagcactca
     7321 ctcctctacg agtacttcac cgtgtacaac gagctgacca aggtgaagta cgtgaccgag
     7381 gggatgagga agccagcttt ccttagcggc gagcaaaaga aggccatcgt cgacctgctg
     7441 ttcaagacca accgcaaggt gaccgtgaag cagctcaagg aggactactt caagaaaatc
     7501 gagtgcttcg actccgtcga gatctccggc gtcgaggata ggttcaatgc ctccctcggg
     7561 acctaccacg acctcctcaa gattatcaag gacaaggact tcctcgacaa cgaggagaac
     7621 gaggacatcc tcgaggacat cgtgctcacc ctcaccctct tcgaggaccg cgagatgatc
     7681 gaggagcgcc tcaagacata cgcccacctc ttcgacgaca aggtgatgaa gcagctgaag
     7741 cgcaggcgct ataccggctg gggcaggctc tctaggaagc tcatcaacgg catccgcgac
     7801 aagcagtccg gcaagacgat cctcgacttc ctcaagtccg acggcttcgc caaccgcaac
     7861 ttcatgcagc tcatccacga cgactccctc accttcaagg aggacatcca aaaggcccag
     7921 gtgtccggcc aaggcgattc cctccatgaa catatcgcca atctcgccgg ctccccggct
     7981 atcaagaagg gcattctcca gaccgtgaag gtggtggacg agctggtgaa ggtgatgggc
     8041 aggcacaagc cagagaacat cgtgatcgag atggcccgcg agaaccagac cacacagaag
     8101 ggccaaaaga actcccgcga gcgcatgaag aggatcgagg agggcattaa ggagctgggc
     8161 tcccagatcc tcaaggagca cccagtcgag aacacccagc tccagaacga gaagctctac
     8221 ctctactacc tccagaacgg ccgcgacatg tacgtggacc aagagctgga catcaaccgc
     8281 ctctccgact acgacgtgga cgctattgtg ccgcagtcct tcctgaagga cgactccatc
     8341 gacaacaagg tgctcacccg ctccgacaag aacaggggca agtccgataa cgtgccgtcc
     8401 gaagaggtcg tcaagaagat gaagaactac tggcgccagc tcctcaacgc caagctcatc
     8461 acccagagga agttcgacaa cctcaccaag gccgagagag gcggcctttc cgagcttgat
     8521 aaggccggct tcatcaagcg ccagctcgtc gagacacgcc agatcacaaa gcacgtggcc
     8581 cagatcctcg actcccgcat gaacaccaag tacgacgaga acgacaagct catccgcgag
     8641 gtgaaggtca tcaccctcaa gtccaagctc gtgtccgact tccgcaagga cttccagttc
     8701 tacaaggtgc gcgagatcaa caactaccac cacgcccacg acgcctacct caatgccgtg
     8761 gtgggcacag ccctcatcaa gaagtaccca aagctcgagt ccgagttcgt gtacggcgac
     8821 tacaaggtgt acgacgtgcg caagatgatc gccaagtccg agcaagagat cggcaaggcg
     8881 accgccaagt acttcttcta ctccaacatc atgaatttct tcaagaccga gatcacgctc
     8941 gccaacggcg agattaggaa gaggccgctc atcgagacaa acggcgagac aggcgagatc
     9001 gtgtgggaca agggcaggga tttcgccaca gtgcgcaagg tgctctccat gccgcaagtg
     9061 aacatcgtga agaagaccga ggttcagacc ggcggcttct ccaaggagtc catcctccca
     9121 aagcgcaact ccgacaagct gatcgcccgc aagaaggact gggacccgaa gaagtatggc
     9181 ggcttcgatt ctccgaccgt ggcctactct gtgctcgtgg ttgccaaggt cgagaagggc
     9241 aagagcaaga agctcaagtc cgtcaaggag ctgctgggca tcacgatcat ggagcgcagc
     9301 agcttcgaga agaacccaat cgacttcctc gaggccaagg gctacaagga ggtgaagaag
     9361 gacctcatca tcaagctccc gaagtacagc ctcttcgagc ttgagaacgg ccgcaagaga
     9421 atgctcgcct ctgctggcga gcttcagaag ggcaacgagc ttgctctccc gtccaagtac
     9481 gtgaacttcc tctacctcgc ctcccactac gagaagctca agggctcccc agaggacaac
     9541 gagcaaaagc agctgttcgt cgagcagcac aagcactacc tcgacgagat catcgagcag
     9601 atctccgagt tctccaagcg cgtgatcctc gccgatgcca acctcgataa ggtgctcagc
     9661 gcctacaaca agcaccgcga taagccaatt cgcgagcagg ccgagaacat catccacctc
     9721 ttcaccctca ccaacctcgg cgctccagcc gccttcaagt acttcgacac caccatcgac
     9781 cgcaagcgct acacctctac caaggaggtt ctcgacgcca ccctcatcca ccagtctatc
     9841 acaggcctct acgagacacg catcgacctc tcacaactcg gcggcgatag tggttctgaa
     9901 actcctggaa catcagaatc ggcgacgccg gagagcgcta ccgtcgtgtc cgggcagaaa
     9961 caagatagac aaggcggcga gaggaggcgt agccagctgg accgcgacca gtgcgcctac
    10021 tgcaaggaga agggccactg ggcaaaagat tgtccaaaga agccccgcgg gccaagagga
    10081 cctcggccgc agacctccct cctttcaggc ggctccagcg gcggctctaa gcggaccgcc
    10141 gacggatcag agttcgagag cccgaagaag aagaggaagg tgtccggcgg ctcatctggc
    10201 ggctccacac tcaatatcga ggacgagtac aggctgcatg agacatccaa ggagcctgac
    10261 gtctccctcg gcagcacatg gctctcagat ttcccacagg cctgggccga gacaggcggc
    10321 atgggcctcg ccgtccgcca ggcgccgctc atcattccac tgaaggcgac ctccacaccg
    10381 gtgagcatca agcagtaccc aatgtctcag gaggcaaggc ttggcatcaa gccacacatt
    10441 cagaggctcc tggaccaggg cattctggtg ccttgccaga gcccgtggaa cacccctctc
    10501 ctgccggtga agaagcctgg cacaaatgac taccgcccgg tccaggatct cagggaggtg
    10561 aacaagcgcg tcgaggatat ccatccgaac gtcccgaacc catacaatct cctgtcaggc
    10621 ctcccgccat ctcaccagtg gtacaccgtg ctcgacctga aggatgcgtt cttctgcctc
    10681 aggctgcatc caacaagcca gcctctcttc gccttcgagt ggcgcgatcc ggagatgggc
    10741 atttcaggcc agctcacctg gacacggctg ccacagggct tcaagaactc tcctaccctc
    10801 ttctgtgagg cgctccatcg ggacctggcc gatttcagga tccagcaccc agacctcatt
    10861 ctcctccagt attatgacga tctcctgctc gccgcgacat ccgagctgga ttgccagcag
    10921 ggaacccgcg cgctgctcca gacactggga aatctgggat acagggcatc agcgaagaag
    10981 gcacagatct gccagaagca ggtcaagtac ctcggctacc tgctcaagga gggacagagg
    11041 tggctgacag aggcaaggaa ggagacagtg atgggccagc ctaccccgaa gacaccacgg
    11101 cagctcaggg agttcctggg caaggcgggc ttctgccgcc tcttcatccc aggattcgcg
    11161 gagatggcgg cgccactcta ccctctgacc aagcctggca cactgttcaa ctggggacca
    11221 gaccagcaga aggcgtacca ggagattaag caggccctgc tcacagcacc tgccctcggc
    11281 ctgccggacc tcacaaagcc attcgagctg ttcgtggatg agaagcaggg ctacgcgaag
    11341 ggagtcctga cacagaagct gggaccatgg aggcgcccag tggcctacct ctccaagaag
    11401 ctggacccag tggctgccgg ctggcctccg tgcctgagga tggtggcggc cattgccgtc
    11461 ctcaccaagg atgccggcaa gctgacaatg ggccagcctc tcgtcattct ggcgccgcat
    11521 gcggtggagg cgctcgtcaa gcagccacct gataggtggc tgtccaacgc gcgcatgacc
    11581 cactaccagg ccctgctcct ggacacagat agggtgcagt tcggcccagt ggtcgccctc
    11641 aatcctgcca cactgctgcc actccctgag gagggcctcc agcataactg cctcgatatt
    11701 ctggcggagg cccatggaac ccgccctgac ctcacagatc agccgctgag cccgaagaag
    11761 aagaggaaag tgggatcagg accagccgcc aagagggtga agctcgattg agagctcaag
    11821 ggtgggcgcg ccgacccagc tttcttgtac aaagtggtga tatcccgcgg ccatggcggc
    11881 cgggagcatg cgacgtcgat ctaactgact agccgcggcc atgctagagt ccgcaaaaat
    11941 caccagtctc tctctacaaa tctatctctc tctatttttc tccagaataa tgtgtgagta
    12001 gttcccagat aagggaatta gggttcttat agggtttcgc tcatgtgttg agcatataag
    12061 aaacccttag tatgtatttg tatttgtaaa atacttctat caataaaatt tctaattcct
    12121 aaaaccaaaa tccagtgacc tggaattcgt aatcatgtca tagctgtttc ctgtgtgaaa
    12181 ttgttatccg ctcacaattc cacacaacat acgagccgga agcataaagt gtaaagcctg
    12241 gggtgcctaa tgagtgagct aactcacatt aattgcgttg cgctcactgc ccgctttcca
    12301 gtcgggaaac ctgtcgtgcc agctgcatta atgaatcggc caacgcgcgg ggagaggcgg
    12361 tttgcgtatt ggctagagca gcttgccaac atggtggagc acgacactct cgtctactcc
    12421 aagaatatca aagatacagt ctcagaagac caaagggcta ttgagacttt tcaacaaagg
    12481 gtaatatcgg gaaacctcct cggattccat tgcccagcta tctgtcactt catcaaaagg
    12541 acagtagaaa aggaaggtgg cacctacaaa tgccatcatt gcgataaagg aaaggctatc
    12601 gttcaagatg cctctgccga cagtggtccc aaagatggac ccccacccac gaggagcatc
    12661 gtggaaaaag aagacgttcc aaccacgtct tcaaagcaag tggattgatg tgaacatggt
    12721 ggagcacgac actctcgtct actccaagaa tatcaaagat acagtctcag aagaccaaag
    12781 ggctattgag acttttcaac aaagggtaat atcgggaaac ctcctcggat tccattgccc
    12841 agctatctgt cacttcatca aaaggacagt agaaaaggaa ggtggcacct acaaatgcca
    12901 tcattgcgat aaaggaaagg ctatcgttca agatgcctct gccgacagtg gtcccaaaga
    12961 tggaccccca cccacgagga gcatcgtgga aaaagaagac gttccaacca cgtcttcaaa
    13021 gcaagtggat tgatgtgata tctccactga cgtaagggat gacgcacaat cccactatcc
    13081 ttcgcaagac ccttcctcta tataaggaag ttcatttcat ttggagagga cacgctgaaa
    13141 tcaccagtct ctctctacaa atctatctct ctcgagcttt cgcagatccc gggggcaatg
    13201 agatatgaaa aagcctgaac tcaccgcgac gtctgtcgag aagtttctga tcgaaaagtt
    13261 cgacagcgtc tccgacctga tgcagctctc ggagggcgaa gaatctcgtg ctttcagctt
    13321 cgatgtagga gggcgtggat atgtcctgcg ggtaaatagc tgcgccgatg gtttctacaa
    13381 agatcgttat gtttatcggc actttgcatc ggccgcgctc ccgattccgg aagtgcttga
    13441 cattggggag tttagcgaga gcctgaccta ttgcatctcc cgccgttcac agggtgtcac
    13501 gttgcaagac ctgcctgaaa ccgaactgcc cgctgttcta caaccggtcg cggaggctat
    13561 ggatgcgatc gctgcggccg atcttagcca gacgagcggg ttcggcccat tcggaccgca
    13621 aggaatcggt caatacacta catggcgtga tttcatatgc gcgattgctg atccccatgt
    13681 gtatcactgg caaactgtga tggacgacac cgtcagtgcg tccgtcgcgc aggctctcga
    13741 tgagctgatg ctttgggccg aggactgccc cgaagtccgg cacctcgtgc acgcggattt
    13801 cggctccaac aatgtcctga cggacaatgg ccgcataaca gcggtcattg actggagcga
    13861 ggcgatgttc ggggattccc aatacgaggt cgccaacatc ttcttctgga ggccgtggtt
    13921 ggcttgtatg gagcagcaga cgcgctactt cgagcggagg catccggagc ttgcaggatc
    13981 gccacgactc cgggcgtata tgctccgcat tggtcttgac caactctatc agagcttggt
    14041 tgacggcaat ttcgatgatg cagcttgggc gcagggtcga tgcgacgcaa tcgtccgatc
    14101 cggagccggg actgtcgggc gtacacaaat cgcccgcaga agcgcggccg tctggaccga
    14161 tggctgtgta gaagtactcg ccgatagtgg aaaccgacgc cccagcactc gtccgagggc
    14221 aaagaaatag agtagatgcc gaccgggatc tgtcgatcga caagctcgag tttctccata
    14281 ataatgtgtg agtagttccc agataaggga attagggttc ctatagggtt tcgctcatgt
    14341 gttgagcata taagaaaccc ttagtatgta tttgtatttg taaaatactt ctatcaataa
    14401 aatttctaat tcctaaaacc aaaatccagt actaaaatcc agatcccccg aattaattcg
    14461 gcgttaattc agtacattaa aaacgtccgc aatgtgttat taagttgtct aagcgtcaat
    14521 ttgtttacac cacaatatat cctgccacca gccagccaac agctccccga ccggcagctc
    14581 ggcacaaaat caccactcga tacaggcagc ccatcagtcc gggacggcgt cagcgggaga
    14641 gccgttgtaa ggcggcagac tttgctcatg ttaccgatgc tattcggaag aacggcaact
    14701 aagctgccgg gtttgaaaca cggatgatct cgcggagggt agcatgttga ttgtaacgat
    14761 gacagagcgt tgctgcctgt gatcaccgcg gtttcaaaat cggctccgtc gatactatgt
    14821 tatacgccaa ctttgaaaac aactttgaaa aagctgtttt ctggtattta aggttttaga
    14881 atgcaaggaa cagtgaattg gagttcgtct tgttataatt agcttcttgg ggtatcttta
    14941 aatactgtag aaaagaggaa ggaaataata aatggctaaa atgagaatat caccggaatt
    15001 gaaaaaactg atcgaaaaat accgctgcgt aaaagatacg gaaggaatgt ctcctgctaa
    15061 ggtatataag ctggtgggag aaaatgaaaa cctatattta aaaatgacgg acagccggta
    15121 taaagggacc acctatgatg tggaacggga aaaggacatg atgctatggc tggaaggaaa
    15181 gctgcctgtt ccaaaggtcc tgcactttga acggcatgat ggctggagca atctgctcat
    15241 gagtgaggcc gatggcgtcc tttgctcgga agagtatgaa gatgaacaaa gccctgaaaa
    15301 gattatcgag ctgtatgcgg agtgcatcag gctctttcac tccatcgaca tatcggattg
    15361 tccctatacg aatagcttag acagccgctt agccgaattg gattacttac tgaataacga
    15421 tctggccgat gtggattgcg aaaactggga agaagacact ccatttaaag atccgcgcga
    15481 gctgtatgat tttttaaaga cggaaaagcc cgaagaggaa cttgtctttt cccacggcga
    15541 cctgggagac agcaacatct ttgtgaaaga tggcaaagta agtggcttta ttgatcttgg
    15601 gagaagcggc agggcggaca agtggtatga cattgccttc tgcgtccggt cgatcaggga
    15661 ggatatcggg gaagaacagt atgtcgagct attttttgac ttactgggga tcaagcctga
    15721 ttgggagaaa ataaaatatt atattttact ggatgaattg ttttagtacc tagaatgcat
    15781 gaccaaaatc ccttaacgtg agttttcgtt ccactgagcg tcagaccccg tagaaaagat
    15841 caaaggatct tcttgagatc ctttttttct gcgcgtaatc tgctgcttgc aaacaaaaaa
    15901 accaccgcta ccagcggtgg tttgtttgcc ggatcaagag ctaccaactc tttttccgaa
    15961 ggtaactggc ttcagcagag cgcagatacc aaatactgtc cttctagtgt agccgtagtt
    16021 aggccaccac ttcaagaact ctgtagcacc gcctacatac ctcgctctgc taatcctgtt
    16081 accagtggct gctgccagtg gcgataagtc gtgtcttacc gggttggact caagacgata
    16141 gttaccggat aaggcgcagc ggtcgggctg aacggggggt tcgtgcacac agcccagctt
    16201 ggagcgaacg acctacaccg aactgagata cctacagcgt gagctatgag aaagcgccac
    16261 gcttcccgaa gggagaaagg cggacaggta tccggtaagc ggcagggtcg gaacaggaga
    16321 gcgcacgagg gagcttccag ggggaaacgc ctggtatctt tatagtcctg tcgggtttcg
    16381 ccacctctga cttgagcgtc gatttttgtg atgctcgtca ggggggcgga gcctatggaa
    16441 aaacgccagc aacgcggcct ttttacggtt cctggccttt tgctggcctt ttgctcacat
    16501 gttctttcct gcgttatccc ctgattctgt ggataaccgt attaccgcct ttgagtgagc
    16561 tgataccgct cgccgcagcc gaacgaccga gcgcagcgag tcagtgagcg aggaagcgga
    16621 tgagcgcctg atgcggtatt ttctccttac gcatctgtgc ggtatttcac accgcatatg
    16681 gtgcactctc agtacaatct gctctgatgc cgcatagtta agccagtata cactccgcta
    16741 tcgctacgtg actgggtcat ggctgcgccc cgacacccgc caacacccgc tgacgcgccc
    16801 tgacgggctt gtctgctccc ggcatccgct tacagacaag ctgtgaccgt ctccgggagc
    16861 tgcatgtgtc agaggttttc accgtcatca ccgaaacgcg cgaggcaggg tgccttgatg
    16921 tgggcgccgg cggtcgagtg gcgacggcgc ggcttgtccg cgccctggta gattgcctgg
    16981 ccgtaggcca gccatttttg agcggccagc ggccgcgata ggccgacgcg aagcggcggg
    17041 gcgtagggag cgcagcgacc gaagggtagg cgctttttgc agcacttcgg ctgtgcgctg
    17101 gccagacagt tatgcacagg ccaggcgggt tttaagagtt ttaataagtt ttaaagagtt
    17161 ttaggcggaa aaatcgcctt ttttctcttt tatatcagtc acttacatgt gtgaccggtt
    17221 cccaatgtac ggctttgggt tcccaatgta cgggttccgg ttcccaatgt acggctttgg
    17281 gttcccaatg tacgtgctat ccacaggaaa cagacctttt cgaccttttt cccctgctag
    17341 ggcaatttgc cctagcatct gctccgtaca ttaggaaccg gcggatgctt cgccctcgat
    17401 caggttgcgg tagcgcatga ctaggatcgg gccagcctgc cccgcctcct ccttcaaatc
    17461 gtactccggc aggtcatttg acccgatcag cttgcgcacg gtgaaacaga acttcttgaa
    17521 ctctccggcg ctgccactgc gttcgtagat cgtcttgaac aaccatctgg cttctgcctt
    17581 gcctgcggcg cggcgtgcca ggcggtagag aaaacggccg atgccgggat cgatcaaaaa
    17641 gtaatcgggg tgaaccgtca gcacgtccgg gttcttgcct tctgtgatct cgcggtacat
    17701 ccaatcagct agctcgatct cgatgtactc cggccgcccg gtttcgctct ttacgatctt
    17761 gtagcggcta atcaaggctt caccctcgga taccgtcacc aggcggccgt tcttggcctt
    17821 cttcgtacgc tgcatggcaa cgtgcgtggt gtttaaccga atgcaggttt ctaccaggtc
    17881 gtctttctgc tttccgccat cggctcgccg gcagaacttg agtacgtccg caacgtgtgg
    17941 acggaacacg cggccgggct tgtctccctt cccttcccgg tatcggttca tggattcggt
    18001 tagatgggaa accgccatca gtaccaggtc gtaatcccac acactggcca tgccggccgg
    18061 ccctgcggaa acctctacgt gcccgtctgg aagctcgtag cggatcacct cgccagctcg
    18121 tcggtcacgc ttcgacagac ggaaaacggc cacgtccatg atgctgcgac tatcgcgggt
    18181 gcccacgtca tagagcatcg gaacgaaaaa atctggttgc tcgtcgccct tgggcggctt
    18241 cctaatcgac ggcgcaccgg ctgccggcgg ttgccgggat tctttgcgga ttcgatcagc
    18301 ggccgcttgc cacgattcac cggggcgtgc ttctgcctcg atgcgttgcc gctgggcggc
    18361 ctgcgcggcc ttcaacttct ccaccaggtc atcacccagc gccgcgccga tttgtaccgg
    18421 gccggatggt ttgcgaccgc tcacgccgat tcctcgggct tgggggttcc agtgccattg
    18481 cagggccggc aggcaaccca gccgcttacg cctggccaac cgcccgttcc tccacacatg
    18541 gggcattcca cggcgtcggt gcctggttgt tcttgatttt ccatgccgcc tcctttagcc
    18601 gctaaaattc atctactcat ttattcattt gctcatttac tctggtagct gcgcgatgta
    18661 ttcagatagc agctcggtaa tggtcttgcc ttggcgtacc gcgtacatct tcagcttggt
    18721 gtgatcctcc gccggcaact gaaagttgac ccgcttcatg gctggcgtgt ctgccaggct
    18781 ggccaacgtt gcagccttgc tgctgcgtgc gctcggacgg ccggcactta gcgtgtttgt
    18841 gcttttgctc attttctctt tacctcatta actcaaatga gttttgattt aatttcagcg
    18901 gccagcgcct ggacctcgcg ggcagcgtcg ccctcgggtt ctgattcaag aacggttgtg
    18961 ccggcggcgg cagtgcctgg gtagctcacg cgctgcgtga tacgggactc aagaatgggc
    19021 agctcgtacc cggccagcgc ctcggcaacc tcaccgccga tgcgcgtgcc tttgatcgcc
    19081 cgcgacacga caaaggccgc ttgtagcctt ccatccgtga cctcaatgcg ctgcttaacc
    19141 agctccacca ggtcggcggt ggcccatatg tcgtaagggc ttggctgcac cggaatcagc
    19201 acgaagtcgg ctgccttgat cgcggacaca gccaagtccg ccgcctgggg cgctccgtcg
    19261 atcactacga agtcgcgccg gccgatggcc ttcacgtcgc ggtcaatcgt cgggcggtcg
    19321 atgccgacaa cggttagcgg ttgatcttcc cgcacggccg cccaatcgcg ggcactgccc
    19381 tggggatcgg aatcgactaa cagaacatcg gccccggcga gttgcagggc gcgggctaga
    19441 tgggttgcga tggtcgtctt gcctgacccg cctttctggt taagtacagc gataaccttc
    19501 atgcgttccc cttgcgtatt tgtttattta ctcatcgcat catatacgca gcgaccgcat
    19561 gacgcaagct gttttactca aatacacatc acctttttag acggcggcgc tcggtttctt
    19621 cagcggccaa gctggccggc caggccgcca gcttggcatc agacaaaccg gccaggattt
    19681 catgcagccg cacggttgag acgtgcgcgg gcggctcgaa cacgtacccg gccgcgatca
    19741 tctccgcctc gatctcttcg gtaatgaaaa acggttcgtc ctggccgtcc tggtgcggtt
    19801 tcatgcttgt tcctcttggc gttcattctc ggcggccgcc agggcgtcgg cctcggtcaa
    19861 tgcgtcctca cggaaggcac cgcgccgcct ggcctcggtg ggcgtcactt cctcgctgcg
    19921 ctcaagtgcg cggtacaggg tcgagcgatg cacgccaagc agtgcagccg cctctttcac
    19981 ggtgcggcct tcctggtcga tcagctcgcg ggcgtgcgcg atctgtgccg gggtgagggt
    20041 agggcggggg ccaaacttca cgcctcgggc cttggcggcc tcgcgcccgc tccgggtgcg
    20101 gtcgatgatt agggaacgct cgaactcggc aatgccggcg aacacggtca acaccatgcg
    20161 gccggccggc gtggtggtgt cggcccacgg ctctgccagg ctacgcaggc ccgcgccggc
    20221 ctcctggatg cgctcggcaa tgtccagtag gtcgcgggtg ctgcgggcca ggcggtctag
    20281 cctggtcact gtcacaacgt cgccagggcg taggtggtca agcatcctgg ccagctccgg
    20341 gcggtcgcgc ctggtgccgg tgatcttctc ggaaaacagc ttggtgcagc cggccgcgtg
    20401 cagttcggcc cgttggttgg tcaagtcctg gtcgtcggtg ctgacgcggg catagcccag
    20461 caggccagcg gcggcgctct tgttcatggc gtaatgtctc cggttctagt cgcaagtatt
    20521 ctactttatg cgactaaaac acgcgacaag aaaacgccag gaaaagggca gggcggcagc
    20581 ctgtcgcgta acttaggact tgtgcgacat gtcgttttca gaagacggct gcactgaacg
    20641 tcagaagccg actgcactat agcagcggag gggttggatc aaagtacttt gatcccgagg
    20701 ggaaccctgt ggttggcatg cacatacaaa tggacgaacg gataaacctt ttcacgccct
    20761 tttaaatatc cgattattct aa
//
