LOCUS       sequence-462792-         852 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  E. coli expression of HLA-A*01:01 containing a cysteine mutation for
            disulfide linkage to mutant beta-2 microglobulin.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 852)
  AUTHORS   Sun Y, Young MC, Woodward CH, Danon JN, Truong HV, Gupta S, Winters 
            TJ, Font-Burgada J, Burslem GM, Sgourakis NG
  TITLE     Universal open MHC-I molecules for rapid peptide loading and 
            enhanced complex stability across HLA allotypes.
  JOURNAL   Proc Natl Acad Sci U S A. 2023 Jun 20;120(25):e2304055120. doi: 
            10.1073/pnas.2304055120. Epub 2023 Jun 13.
  PUBMED    37310998
REFERENCE   2  (bases 1 to 852)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Proc Natl 
            Acad Sci U S A."; date: "2023-06-20"; volume: "120(25):e2304055120. 
            doi"; pages: " 10.1073/pnas.2304055120. Epub 2023 Jun 13"
COMMENT     Sequence Label: OPEN-HLA-A*01:01
FEATURES             Location/Qualifiers
     source          1..852
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 catatggcta gcggttctca ttctatgaga tatttcttca catccgtgtc ccggcccggc
       61 cgcggggagc cccgcttcat cgccgtgggc tacgtggacg acacgcagtt cgtgcggttc
      121 gacagcgacg ccgcgagcca gaagatggag ccgcgggcgc cgtggataga gcaggagggg
      181 ccggagtatt gggaccagga gacacggaat atgaaggccc actcacagac tgaccgagcg
      241 aacctgggga ccctgcgcgg ctactacaac cagagcgagg acggttctca caccatccag
      301 ataatgtatg gctgcgacgt ggggccggac gggcgcttcc tccgcgggta ccggcaggac
      361 gcctacgact gcaaggatta catcgccctg aacgaggacc tgcgttcttg gaccgcggcg
      421 gacatggcag ctcagatcac caagcgcaag tgggaggcgg tccatgcggc ggagcagcgg
      481 agagtctacc tggagggccg gtgcgtggac gggctccgca gatacctgga gaacgggaag
      541 gagacgctgc agcgcacgga cccccccaag acacatatga cccaccaccc catctctgac
      601 catgaggcca ccctgaggtg ctgggccctg ggcttctacc ctgcggagat cacactgacc
      661 tggcagcggg atggggagga ccagacccag gacacggagc tcgtggagac caggcctgca
      721 ggggatggaa ccttccagaa gtgggcggct gtggtggtgc cttctggaga ggagcagaga
      781 tacacctgcc atgtgcagca tgagggtctg cccaagcccc tcaccctgag atgggagctg
      841 tcttcccagc cc
//
