LOCUS       sequence-46453-e         886 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 886)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 886)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-GRK7
FEATURES             Location/Qualifiers
     source          1..886
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    19..118
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 acctcgatcg ctggatggca aataatgatt ttattttgac tgatagtgac ctgttcgttg
       61 caacaaattg ataagcaatg ctttcttata atgccaactt tgtacaagaa agttggcaac
      121 aataacaaac acacgccaga cttggatgaa ttaccctcct cacaacccgt aggtctgttg
      181 gggtcattca gttcctcaaa cagtcccgtt tctataattt cttcctgcca tgctatagga
      241 acagcacctg tcgcaaagtt tttgaagaac tgcttatctt tgtcatcaaa ttccaccccc
      301 cgaacctcag agaaatcatc aatttcagcg atgtctttgg cataaaccac tgaagggtct
      361 ggcacaaatg ggggttcaat taggccagct tccaggcgag gaaagttgat cgttttaaag
      421 aaatgatgtt tcctgggatc atcagacttt tctctgcttc ctaagcgttg ctctggtttc
      481 ttagccaaga agagcctgca aatatctttt gcttcctctg tgaagttatc atgctggaat
      541 ttgacctcgt cttgcagagt tctttgcttc agatcctctt tactgacctt ttccttgtaa
      601 tctttgaatg gtgttcgtcc agcaaccatt tcataaatgc tgcatcccat ggcaaaccag
      661 tccacaggat aggaataact taccttttcc attaggatct caggagccat gtaaccattg
      721 gttccagccc tctgggtgat gggcttgcca cccttcatct ccacggccag ccccaggtca
      781 gataacctgc agttgccgag gtcatccaga agcacattct caggcttcat gtcccgatag
      841 acgatgccga gttcatggag gtgcagcatc ccacaggcta tctggg
//
