LOCUS       sequence-46455-e         889 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 889)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 889)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-MARK2
FEATURES             Location/Qualifiers
     source          1..889
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    17..116
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 ctggatcagc tggatggcaa taatgatttt attttgactg atagtgacct gttcgttgca
       61 acaaattgat aagcaatgct ttcttataat gccaactttg tacaagaaag ttggcaaaag
      121 cttcagctcg ttggctattt tggaggcaat gtttttgaag gccatggagg tgcccgatat
      181 ccgcttaaat cgaaccccgt tgagagagag ccgcggcagt ttgcacacct ccatctccca
      241 ctgcacgaag tcctcgtggc ccggcgtgcc gtgcatgcac agcagcatgt acttctcatg
      301 cagctcgctc tggcagctgt tcgcgtccag caccttgcgg atctcccgca tcatctcgtt
      361 gggctccatg gagctcgtgg tcttcatact ccacgtgaag cggagggagc ggggcttggc
      421 ctcccgaaat tcttcctttt ctttgtcgtt gccgccactg cccaccacgt gaggtctgag
      481 cgtctccact cggtctttgc tttcaggttc attcaggttc ctgcgtacaa acttggaggt
      541 gaacttgctg aagatgctcc cagaggcccc ccgccggccc tggctgtggc cagagggaga
      601 ggctggggtc acaccgtagg gcaaattctg ctggtcccgc acctgtcgga gctgcccagc
      661 atggaaggtg cttcggctgg acacaccccg ggggaagtta gttcggtctg gggctccacc
      721 actgctgctg atgttgtggg cggatgggga ggcaacaggg acacgctggg gggctgtgct
      781 gtctttgcca ttctggatgg aggcctggcc gaggctggcc cgctccaaaa gtggggaatt
      841 cctgcttcga tttgtgctgg tggagaggac gctgttcgtg gagggggtt
//
