LOCUS       sequence-46456-e         868 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 868)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 868)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-SNRK
FEATURES             Location/Qualifiers
     source          1..868
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    14..113
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 gatcagctgg atggcaataa tgattttatt ttgactgata gtgacctgtt cgttgcaaca
       61 aattgataag caatgctttc ttataatgcc aactttgtac aagaaagttg gcaagatgac
      121 atggcaacag ctggctgggc tggatgcgca cagcagcccc tccttagggt tccgctggat
      181 gttcacagag atggtctttt cgcacagagg tagctgcagc acgttatttt tcaggttctt
      241 gctctttatc cgttccaatt cagtggtggt atctgccatg tggtcataca aaaactttat
      301 gccccccact gcagggacat gccctgcatt ccctgtggag ctaatgcatt ttttctcctt
      361 aaatatctct tggactatca cactgcaaaa tgacaagcca ttctgtggat caataatgta
      421 cttggtgctc ccatgaacct gggagccgag gcacatgctc atgagtttga cgctctcatc
      481 cacctcccca tcactgcgag aggccagatg catggacttg ctggggccgg cacagcggct
      541 tgtggtaccc gatgtattga tggcgttgcc acccgactcg ctggagtgac cgttctcacc
      601 tgagtcgctc tcgctggtgc tggtgttgtc cttgactcca ctgtcattgc ttggcttgcg
      661 agactgacgg acatctcgcg tgctaccaag gagtgcctgt gagctcatcc tcaagtgcct
      721 gggagtacgt caattctgga tctctatgac tgcctcaact gctctcagat tcagcatcgg
      781 ctgtgcagat atcgactgca gctcgatctc ttgctttgct ttctcgatcg gtggaagcag
      841 taggaagcat gtgcttgaga tgctgtat
//
