LOCUS       sequence-465002-       14991 bp    DNA     circular SYN 15-DEC-2025
DEFINITION  Red light-inducible Cre-C; Cre-230C-PhyA.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      synthetic DNA construct
  ORGANISM  synthetic DNA construct
REFERENCE   1  (bases 1 to 14991)
  AUTHORS   Tous C, Kinstlinger IS, Rice MEL, Deng J, Wong WW
  TITLE     Multiplexing light-inducible recombinases to control cell fate, 
            Boolean logic, and cell patterning in mammalian cells.
  JOURNAL   Sci Adv. 2025 May 9;11(19):eadt1971. doi: 10.1126/sciadv.adt1971. 
            Epub 2025 May 9.
  PUBMED    40344052
REFERENCE   2  (bases 1 to 14991)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; journalName: "Sci Adv."; 
            date: "2025-05-9"; volume: "11(19):eadt1971. doi"; pages: " 
            10.1126/sciadv.adt1971. Epub 2025 May 9"
COMMENT     Sequence Label: CT362
FEATURES             Location/Qualifiers
     source          1..14991
                     /mol_type="other DNA"
                     /organism="synthetic DNA construct"
     polyA_signal    180..235
                     /label=beta-globin poly(A) signal
                     /note="rabbit beta-globin polyadenylation signal (Gil and 
                     Proudfoot, 1987)"
     primer_bind     complement(596..612)
                     /label=M13 rev
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     protein_bind    620..636
                     /label=lac operator
                     /bound_moiety="lac repressor encoded by lacI"
                     /note="The lac repressor binds to the lac operator to 
                     inhibit transcription in E. coli. This inhibition can be 
                     relieved by adding lactose or 
                     isopropyl-beta-D-thiogalactopyranoside (IPTG)."
     promoter        complement(join(644..650,651..668,669..674))
                     /label=lac promoter
                     /note="promoter for the E. coli lac operon"
     protein_bind    689..710
                     /label=CAP binding site
                     /bound_moiety="E. coli catabolite activator protein"
                     /note="CAP binding activates transcription in the presence 
                     of cAMP."
     rep_origin      795..929
                     /label=SV40 ori
                     /note="SV40 origin of replication"
     polyA_signal    949..1083
                     /label=SV40 poly(A) signal
                     /note="SV40 polyadenylation signal"
     rep_origin      complement(1322..1910)
                     /direction=LEFT
                     /label=ori
                     /note="high-copy-number ColE1/pMB1/pBR322/pUC origin of 
                     replication"
     CDS             complement(join(2081..2872,2873..2941))
                     /codon_start=1
                     /gene="bla"
                     /product="beta-lactamase"
                     /label=AmpR
                     /note="confers resistance to ampicillin, carbenicillin, and
                     related antibiotics"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRIDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
     promoter        complement(2942..3046)
                     /gene="bla"
                     /label=AmpR promoter
     CDS             3298..3676
                     /label=ISS
                     /note="immunostimulatory sequence from the AmpR gene; 
                     contains unmethylated CpG dinucleotides in the context of 
                     5'-AACGTT-3' (Sato et al., 1996)"
     rep_origin      4145..4733
                     /direction=RIGHT
                     /label=ori
                     /note="high-copy-number ColE1/pMB1/pBR322/pUC origin of 
                     replication"
     polyA_signal    4972..5106
                     /label=SV40 poly(A) signal
                     /note="SV40 polyadenylation signal"
     rep_origin      5126..5260
                     /label=SV40 ori
                     /note="SV40 origin of replication"
     protein_bind    5345..5366
                     /label=CAP binding site
                     /bound_moiety="E. coli catabolite activator protein"
                     /note="CAP binding activates transcription in the presence 
                     of cAMP."
     promoter        join(5381..5386,5387..5404,5405..5411)
                     /label=lac promoter
                     /note="promoter for the E. coli lac operon"
     protein_bind    5419..5435
                     /label=lac operator
                     /bound_moiety="lac repressor encoded by lacI"
                     /note="The lac repressor binds to the lac operator to 
                     inhibit transcription in E. coli. This inhibition can be 
                     relieved by adding lactose or 
                     isopropyl-beta-D-thiogalactopyranoside (IPTG)."
     primer_bind     5443..5459
                     /label=M13 rev
                     /note="common sequencing primer, one of multiple similar 
                     variants"
     polyA_signal    5820..5875
                     /label=beta-globin poly(A) signal
                     /note="rabbit beta-globin polyadenylation signal (Gil and 
                     Proudfoot, 1987)"
     polyA_signal    6180..6404
                     /label=bGH poly(A) signal
                     /note="bovine growth hormone polyadenylation signal"
     CDS             complement(6414..6434)
                     /codon_start=1
                     /product="nuclear localization signal of SV40 (simian virus
                     40) large T antigen"
                     /label=SV40 NLS
                     /translation="PKKKRKV"
     regulatory      8666..8675
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
     intron          8804..9820
                     /label=chimeric intron
                     /note="chimera between introns from chicken beta-actin and 
                     rabbit beta-globin"
     promoter        complement(9821..10097)
                     /label=chicken beta-actin promoter
     enhancer        10099..10478
                     /label=CMV enhancer
                     /note="human cytomegalovirus immediate early enhancer"
     promoter        10509..10613
                     /gene="bla"
                     /label=AmpR promoter
     regulatory      12371..12380
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
     CDS             14612..14632
                     /codon_start=1
                     /product="nuclear localization signal of SV40 (simian virus
                     40) large T antigen"
                     /label=SV40 NLS
                     /translation="PKKKRKV"
     polyA_signal    14642..14866
                     /label=bGH poly(A) signal
                     /note="bovine growth hormone polyadenylation signal"
ORIGIN
        1 agattaccac aactccgagc ccttccaccg ctagcgcact cctcaggtgc aggctgccta
       61 tcagaaggtg gtggctggtg tggccaatgc cctggctcac aaataccact gagatctttt
      121 tccctctgcc aaaaattatg gggacatcat gaagcccctt gagcatctga cttctggcta
      181 ataaaggaaa tttattttca ttgcaatagt gtgttggaat tttttgtgtc tctcactcgg
      241 aaggacatat gggagggcaa atcatttaaa acatcagaat gagtatttgg tttagagttt
      301 ggcaacatat gcccatatgc tggctgccat gaacaaaggt tggctataaa gaggtcatca
      361 gtatatgaaa cagccccctg ctgtccattc cttattccat agaaaagcct tgacttgagg
      421 ttagattttt tttatatttt gttttgtgtt atttttttct ttaacatccc taaaattttc
      481 cttacatgtt ttactagcca gatttttcct cctctcctga ctactcccag tcatagctgt
      541 ccctcttctc ttatggagat ccctcgacct gcagcccaag cttggcgtaa tcatggtcat
      601 agctgtttcc tgtgtgaaat tgttatccgc tcacaattcc acacaacata cgagccggaa
      661 gcataaagtg taaagcctgg ggtgcctaat gagtgagcta actcacatta attgcgttgc
      721 gctcactgcc cgctttccag tcgggaaacc tgtcgtgcca gcggatccgc atctcaatta
      781 gtcagcaacc atagtcccgc ccctaactcc gcccagttcc gcccattctc cgccccatgg
      841 ctgactaatt ttttttattt atgcagaggc cgaggccgcc tcggcctctg agctattcca
      901 gaagtagtga ggaggctttt ttggaggcct aggcttttgc aaaaagctaa cttgtttatt
      961 gcagcttata atggttacaa ataaagcaat agcatcacaa atttcacaaa taaagcattt
     1021 ttttcactgc attctagttg tggtttgtcc aaactcatca atgtatctta tcatgtctgg
     1081 atccgctgca ttaatgaatc ggccaacgcg cggggagagg cggtttgcgt attgggcgct
     1141 cttccgcttc ctcgctcact gactcgctgc gctcggtcgt tcggctgcgg cgagcggtat
     1201 cagctcactc aaaggcggta atacggttat ccacagaatc aggggataac gcaggaaaga
     1261 acatgtgagc aaaaggccag caaaaggcca ggaaccgtaa aaaggccgcg ttgctggcgt
     1321 ttttccatag gctccgcccc cctgacgagc atcacaaaaa tcgacgctca agtcagaggt
     1381 ggcgaaaccc gacaggacta taaagatacc aggcgtttcc ccctggaagc tccctcgtgc
     1441 gctctcctgt tccgaccctg ccgcttaccg gatacctgtc cgcctttctc ccttcgggaa
     1501 gcgtggcgct ttctcatagc tcacgctgta ggtatctcag ttcggtgtag gtcgttcgct
     1561 ccaagctggg ctgtgtgcac gaaccccccg ttcagcccga ccgctgcgcc ttatccggta
     1621 actatcgtct tgagtccaac ccggtaagac acgacttatc gccactggca gcagccactg
     1681 gtaacaggat tagcagagcg aggtatgtag gcggtgctac agagttcttg aagtggtggc
     1741 ctaactacgg ctacactaga agaacagtat ttggtatctg cgctctgctg aagccagtta
     1801 ccttcggaaa aagagttggt agctcttgat ccggcaaaca aaccaccgct ggtagcggtg
     1861 gtttttttgt ttgcaagcag cagattacgc gcagaaaaaa aggatctcaa gaagatcctt
     1921 tgatcttttc tacggggtct gacgctcagt ggaacgaaaa ctcacgttaa gggattttgg
     1981 tcatgagatt atcaaaaagg atcttcacct agatcctttt aaattaaaaa tgaagtttta
     2041 aatcaatcta aagtatatat gagtaaactt ggtctgacag ttaccaatgc ttaatcagtg
     2101 aggcacctat ctcagcgatc tgtctatttc gttcatccat agttgcctga ctccccgtcg
     2161 tgtagataac tacgatacgg gagggcttac catctggccc cagtgctgca atgataccgc
     2221 gagacccacg ctcaccggct ccagatttat cagcaataaa ccagccagcc ggaagggccg
     2281 agcgcagaag tggtcctgca actttatccg cctccatcca gtctattaat tgttgccggg
     2341 aagctagagt aagtagttcg ccagttaata gtttgcgcaa cgttgttgcc attgctacag
     2401 gcatcgtggt gtcacgctcg tcgtttggta tggcttcatt cagctccggt tcccaacgat
     2461 caaggcgagt tacatgatcc cccatgttgt gcaaaaaagc ggttagctcc ttcggtcctc
     2521 cgatcgttgt cagaagtaag ttggccgcag tgttatcact catggttatg gcagcactgc
     2581 ataattctct tactgtcatg ccatccgtaa gatgcttttc tgtgactggt gagtactcaa
     2641 ccaagtcatt ctgagaatag tgtatgcggc gaccgagttg ctcttgcccg gcgtcaatac
     2701 gggataatac cgcgccacat agcagaactt taaaagtgct catcattgga aaacgttctt
     2761 cggggcgaaa actctcaagg atcttaccgc tgttgagatc cagttcgatg taacccactc
     2821 gtgcacccaa ctgatcttca gcatctttta ctttcaccag cgtttctggg tgagcaaaaa
     2881 caggaaggca aaatgccgca aaaaagggaa taagggcgac acggaaatgt tgaatactca
     2941 tactcttcct ttttcaatat tattgaagca tttatcaggg ttattgtctc atgagcggat
     3001 acatatttga atgtatttag aaaaataaac aaataggggt tccgcgcaca tttccccgaa
     3061 aagtgccacc tgggtcgaca ttgattattg actagttatt aatagtaatc aattacgggg
     3121 tcattagttc atagcccata tatggagttc cgcgttacat aacttacggt aaatggcccg
     3181 cctggctgac cgcccaacga cccccgccca ttgacgtcaa tcagttgggt gcacgagtgg
     3241 gttacatcga actggatctc aacagcggta agatccttga gagttttcgc cccgaagaac
     3301 gttttccaat gatgagcact tttaaagttc tgctatgtgg cgcggtatta tcccgtattg
     3361 acgccgggca agagcaactc ggtcgccgca tacactattc tcagaatgac ttggttgagt
     3421 actcaccagt cacagaaaag catcttacgg atggcatgac agtaagagaa ttatgcagtg
     3481 ctgccataac catgagtgat aacactgcgg ccaacttact tctgacaacg atcggaggac
     3541 cgaaggagct aaccgctttt ttgcacaaca tgggggatca tgtaactcgc cttgatcgtt
     3601 gggaaccgga gctgaatgaa gccataccaa acgacgagcg tgacaccacg atgcctgtag
     3661 caatggcaac aacgttgcgc aaactattaa ctggcgaact acttactcta gcttcccggc
     3721 aacaattaat agactggatg gaggcggata aagttgcagg accacttctg cgctcggccc
     3781 ttccggctgg ctggtttatt gctgataaat ctggagccgg tgagcgtggg tctcgcggta
     3841 tcattgcagc actggggcca gatggtaagc cctcccgtat cgtagttatc tacacgacgg
     3901 ggagtcaggc aactatggat gaacgaaata gacagatcgc tgagataggt gcctcactga
     3961 ttaagcattg gtaactgtca gaccaagttt actcatatat actttagatt gatttaaaac
     4021 ttcattttta atttaaaagg atctaggtga agatcctttt tgataatctc atgaccaaaa
     4081 tcccttaacg tgagttttcg ttccactgag cgtcagaccc cgtagaaaag atcaaaggat
     4141 cttcttgaga tccttttttt ctgcgcgtaa tctgctgctt gcaaacaaaa aaaccaccgc
     4201 taccagcggt ggtttgtttg ccggatcaag agctaccaac tctttttccg aaggtaactg
     4261 gcttcagcag agcgcagata ccaaatactg ttcttctagt gtagccgtag ttaggccacc
     4321 acttcaagaa ctctgtagca ccgcctacat acctcgctct gctaatcctg ttaccagtgg
     4381 ctgctgccag tggcgataag tcgtgtctta ccgggttgga ctcaagacga tagttaccgg
     4441 ataaggcgca gcggtcgggc tgaacggggg gttcgtgcac acagcccagc ttggagcgaa
     4501 cgacctacac cgaactgaga tacctacagc gtgagctatg agaaagcgcc acgcttcccg
     4561 aagggagaaa ggcggacagg tatccggtaa gcggcagggt cggaacagga gagcgcacga
     4621 gggagcttcc agggggaaac gcctggtatc tttatagtcc tgtcgggttt cgccacctct
     4681 gacttgagcg tcgatttttg tgatgctcgt caggggggcg gagcctatgg aaaaacgcca
     4741 gcaacgcggc ctttttacgg ttcctggcct tttgctggcc ttttgctcac atgttctttc
     4801 ctgcgttatc ccctgattct gtggataacc gtattaccgc ctttgagtga gctgataccg
     4861 ctcgccgcag ccgaacgacc gagcgcagcg agtcagtgag cgaggaagcg gaagagcgcc
     4921 caatacgcaa accgcctctc cccgcgcgtt ggccgattca ttaatgcagc ggatccagac
     4981 atgataagat acattgatga gtttggacaa accacaacta gaatgcagtg aaaaaaatgc
     5041 tttatttgtg aaatttgtga tgctattgct ttatttgtaa ccattataag ctgcaataaa
     5101 caagttagct ttttgcaaaa gcctaggcct ccaaaaaagc ctcctcacta cttctggaat
     5161 agctcagagg ccgaggcggc ctcggcctct gcataaataa aaaaaattag tcagccatgg
     5221 ggcggagaat gggcggaact gggcggagtt aggggcggga ctatggttgc tgactaattg
     5281 agatgcggat ccgctggcac gacaggtttc ccgactggaa agcgggcagt gagcgcaacg
     5341 caattaatgt gagttagctc actcattagg caccccaggc tttacacttt atgcttccgg
     5401 ctcgtatgtt gtgtggaatt gtgagcggat aacaatttca cacaggaaac agctatgacc
     5461 atgattacgc caagcttggg ctgcaggtcg agggatctcc ataagagaag agggacagct
     5521 atgactggga gtagtcagga gaggaggaaa aatctggcta gtaaaacatg taaggaaaat
     5581 tttagggatg ttaaagaaaa aaataacaca aaacaaaata taaaaaaaat ctaacctcaa
     5641 gtcaaggctt ttctatggaa taaggaatgg acagcagggg gctgtttcat atactgatga
     5701 cctctttata gccaaccttt gttcatggca gccagcatat gggcatatgt tgccaaactc
     5761 taaaccaaat actcattctg atgttttaaa tgatttgccc tcccatatgt ccttccgagt
     5821 gagagacaca aaaaattcca acacactatt gcaatgaaaa taaatttcct ttattagcca
     5881 gaagtcagat gctcaagggg cttcatgatg tccccataat ttttggcaga gggaaaaaga
     5941 tctcagtggt atttgtgagc cagggcattg gccacaccag ccaccacctt ctgataggca
     6001 gcctgcacct gaggagtgcg ctagcggtgg aagggctcgg agttgtggta atctatgtat
     6061 cctgggcggc cgcgcttgga ttctgcgttt gtttccgtct acgaactccc agcggtacac
     6121 gctacagggc gcgtggggat accccctaga gccccagctg gttctttccg cctcagaagc
     6181 catagagccc accgcatccc cagcatgcct gctattgtct tcccaatcct cccccttgct
     6241 gtcctgcccc accccacccc ccagaataga atgacaccta ctcagacaat gcgatgcaat
     6301 ttcctcattt tattaggaaa ggacagtggg agtggcacct tccagggtca aggaaggcac
     6361 gggggagggg caaacaacag atggctggca actagaaggc acaggaattc tcacaccttc
     6421 cgctttttct tggggtcccc atcctcgagc agcctcacca tggccccagt ctcagagtcc
     6481 aggtttctga tgtagttcat cacaatgttc acattggtcc agccaccagc ctgcatgatt
     6541 tcagggatgg acacaccagc cctggccatg tccctggcag cacccactct ggcagagtgg
     6601 ccagaccagg ccaggtatct ctgcccagag tcatccttgg caccatagat caggcggtgg
     6661 gtggcctcaa agatcccttc cagggcccgg gtggacagtt gggaggtggc agaaggggca
     6721 gccacaccat tctttctgac ccggcagaac aggtagttgt tggggtcatc agccacggta
     6781 ccgctgccac cacttgatcc ggagccagac cctccggatt ggattccatc aatcttgaga
     6841 tcgttgagct tgctatagat cacctttgtg ttcacgtcgg tggtctcgct gtccttaaag
     6901 gcgttacgta agatgagctg taaagagtgg atggcatcca tttcgtagtc cttccaaggt
     6961 aagcttctgg tcttcaccac ctccagaaaa gccttgaagg aggatctggg gtgcatcctt
     7021 ctggcatcgt ccctatcatc ggggtcgtgt ttggcgccgc cccatctcac ttcgccggcg
     7081 gtatgggaac gaaaccagaa aatcatatct ttgctgctga tacgaacggc agccattccg
     7141 cagacgctgt cgcctaaaga taaagcccta ggaaagccag cgtcgtgtaa agaatcggtg
     7201 cttaaaccgg tggaatccat gtggtactca cacagccaag aagcgatttc ttgtaaatgg
     7261 aactcgctag gggtggtgcc cagcttccag atcttgtcct tgtataataa ggcggcgccg
     7321 tcgcacttga ctaaatccat aatattgggg gactggctca cgatgccgag gggagcgtcc
     7381 ctcatgagca tgtcgcagag gagtgtctgg gtacgtaaaa tgttcttctc caccatctgg
     7441 ttgtccagct cgacctcctt gttgacgtgg atggcaaaca cttgggctaa aaattcacaa
     7501 gcataacgta agggaaaagg gacaaatctg ggggtggtgt tgtggcagac cactaaaccc
     7561 cacagcctct ttctcttctg aggctgtgtg gtggcatcgg gagcatcgcc ctctccatcc
     7621 tcctcattca ccaccacggc catcactaaa gaagcgatgc tgtccatatt ggccatgtat
     7681 tgcagatgac aagagtgggg agctcttaaa gtgctgccgc agagggttaa atcgaagctc
     7741 agcttctcat cttgtaaaac cctagcgtgc ttggcgttgc agtccacgat cattctcacc
     7801 ttgttcttca taaataaaaa tctggcagct tgggggatgt ctgtggcggg atagtgtaaa
     7861 cctaaatagg gttctaaacc gggcttggtc acttcgctca ccacctcgcc gtggtcgtcc
     7921 tcgtggaact tgtaggccat gacacgatcg taaccagtca gctcgaagac ttcttgcacc
     7981 atggtgtcgc acagcctctc catgcttccg ctgggtaaag actggagtct ggtgatggcc
     8041 ttggcggcca gcttatagct ctgtaaagct ccggcggctg tcatgggcac ttcatagggc
     8101 ttaacgggtt cgaagtcgat gatgatggat ccggtcaccc tatggataat ggcgtagaag
     8161 ggcttggcgg atgtacgaca atggacgagg atagggttca gtaaagacac gtcgccgaag
     8221 ccgagagcct tctgtaaagc ggaagcgctg ggagcggtaa ataaagatct gatatcggtg
     8281 ccgatgccca gaacggggtg ctctcccacg ctaggcacgg cgtgggaagc cattgtgagc
     8341 agttcggagg cgttctcgga gtaggcgatg accttgaagg tcttttcgtc taaagccagt
     8401 aaacatccaa agggctggat cagcttgccc ttctggatat gatggaggta ggttgtggtg
     8461 accttgtcgc tcctaggagg ctggttctcg accacgggac cagtcaccct cacgctggtg
     8521 gagtaatcaa aggaggagcc gctctcctcg aaatcggcgt gcagtttggc gtccacggtg
     8581 gtctgagcga tgatacgagc ggagtgacga gatctacgag atccctcgct ggactgtgtg
     8641 ggacgagatc cgctcatctt cttctccatg gtggcggcac gcgtgcgaga cgagacgaga
     8701 cagcctgaga atggatgcga gtaatgggcg cgccttcgct cgaattaatc aattctttgc
     8761 caaaatgatg agacagcaca ataaccagca cgttgcccag gagctgtagg aaaaagaaga
     8821 aggcatgaac atggttagca gaggctctag agccgccggt cacacgccag aagccgaacc
     8881 ccgccctgcc ccgtcccccc cgaaggcagc cgtccccccg cggacagccc cgaggctgga
     8941 gagggagaag gggacggcgg cgcggcgacg cacgaaggcc ctccccgccc atttccttcc
     9001 tgccggcgcc gcaccgcttc gccccgcgcc cgctagaggg ggtgcggcgg cgcctcccag
     9061 atttcggctc cgcacagatt tgggacaaag gaagtccctg cgccctctcg cacgattacc
     9121 ataaaaggca atggctgcgg ctcgccgcgc ctcgacagcc gccggcgctc cgggggccgc
     9181 cgcgcccctc ccccgagccc tccccggccc gaggcggccc cgccccgccc ggcaccccca
     9241 cctgccgcca ccccccgccc ggcacggcga gccccgcgcc acgccccgta cggagccccg
     9301 cacccgaagc cgggccgtgc tcagcaactc ggggaggggg gtgcaggggg ggttgcagcc
     9361 cgaccgacgc gcccacaccc cctgctcacc cccccacgca cacaccccgc acgcagcctt
     9421 tgttcccctc gcagcccccc ccgcaccgcg gggcaccgcc cccggccgcg ctcccctcgc
     9481 gcacactgcg gagcgcacaa agccccgcgc cgcgcccgca gcgctcacag ccgccgggca
     9541 gcgcggagcc gcacgcggcg ctccccacgc acacacacac gcacgcaccc cccgagccgc
     9601 tccccccgca caaagggccc tcccggagcc cctcaaggct ttcacgcagc cacagaaaag
     9661 aaacaagccg tcattaaacc aagcgctaat tacagcccgg aggagaaggg ccgtcccgcc
     9721 cgctcacctg tgggagtaac gcggtcagtc agagccgggg cgggcggcgc gaggcggcgg
     9781 cggagcgggg cacggggcga aggcagcgcg cagcgactcc cgcccgccgc gcgcttcgct
     9841 ttttataggg ccgccgccgc cgccgcctcg ccataaaagg aaactttcgg agcgcgccgc
     9901 tctgattggc tgccgccgca cctctccgcc tcgccccgcc ccgcccctcg ccccgccccg
     9961 ccccgcctgg cgcgcgcccc cccccccccc cgcccccatc gctgcacaaa ataattaaaa
    10021 aataaataaa tacaaaattg ggggtgggga ggggggggag atggggagag tgaagcagaa
    10081 cgtggggctc acctcgacca tggtaatagc gatgactaat acgtagatgt actgccaagt
    10141 aggaaagtcc cataaggtca tgtactgggc ataatgccag gcgggccatt taccgtcatt
    10201 gacgtcaata gggggcgtac ttggcatatg atacacttga tgtactgcca agtgggcagt
    10261 ttaccgtaaa tactccaccc attgacgtca atggaaagtc cctattggcg ttactatggg
    10321 aacatacgtc attattgacg tcaatgggcg ggggtcgttg ggcggtcagc caggcgggcc
    10381 atttaccgta agttatgtaa cgcggaactc catatatggg ctatgaacta atgaccccgt
    10441 aattgattac tattaataac tagtcaataa tcaatgtcga cccaggtggc acttttcggg
    10501 gaaatgtgcg cggaacccct atttgtttat ttttctaaat acattcaaat atgtatccgc
    10561 tcatgagaca ataaccctga taaatgcttc aataatattg aaaaaggaag agtatgagta
    10621 ttcaacattt ccgtgtcgcc cttattccct tttttgcggc attttgcctt cctgtttttg
    10681 ctcacccaga aacgctggtg aaagtaaaag atgctgaaga tgttcccata gtaacgccaa
    10741 tagggacttt ccattgacgt caatgggtgg agtatttacg gtaaactgcc cacttggcag
    10801 tacatcaagt gtatcatatg ccaagtacgc cccctattga cgtcaatgac ggtaaatggc
    10861 ccgcctggca ttatgcccag tacatgacct tatgggactt tcctacttgg cagtacatct
    10921 acgtattagt catcgctatt accatggtcg aggtgagccc cacgttctgc ttcactctcc
    10981 ccatctcccc cccctcccca cccccaattt tgtatttatt tattttttaa ttattttgtg
    11041 cagcgatggg ggcggggggg gggggggggg gcgcgccggg gggggggggg gggggggggg
    11101 gggggggggg gggggggggg gggggggggg gggggggcag gggggggggg gggggggcca
    11161 aatttctttt tttggggggg gggggggggg gggggccccc aaaaaaaaaa agggcccggg
    11221 gggggggggg cgcgccgcgc ggccttcgcc ccgtgccccg ctccgccgcc gcctcgcgcc
    11281 gcccgccccg gctctgactg accgcgttac tcccacaggt gagcgggcgg gacggccctt
    11341 ctcctccggg ctgtaattag cgcttggttt aatgacggct tgtttctttt ctgtggctgc
    11401 gtgaaagcct tgaggggctc cgggagggcc ctttgtgcgg ggggagcggc tcggggggtg
    11461 cgtgcgtgtg tgtgtgcgtg gggagcgccg cgtgcggctc cgcgctgccc ggcggctgtg
    11521 agcgctgcgg gcgcggcgcg gggctttgtg cgctccgcag tgtgcgcgag gggagcgcgg
    11581 ccgggggcgg tgccccgcgg tgcggggggg gctgcgaggg gaacaaaggc tgcgtgcggg
    11641 gtgtgtgcgt gggggggtga gcagggggtg tgggcgcgtc ggtcgggctg caaccccccc
    11701 tgcacccccc tccccgagtt gctgagcacg gcccggcttc gggtgcgggg ctccgtacgg
    11761 ggcgtggcgc ggggctcgcc gtgccgggcg gggggtggcg gcaggtgggg gtgccgggcg
    11821 gggcggggcc gcctcgggcc ggggagggct cgggggaggg gcgcggcggc ccccggagcg
    11881 ccggcggctg tcgaggcgcg gcgagccgca gccattgcct tttatggtaa tcgtgcgaga
    11941 gggcgcaggg acttcctttg tcccaaatct gtgcggagcc gaaatctggg aggcgccgcc
    12001 gcaccccctc tagcgggcgc ggggcgaagc ggtgcggcgc cggcaggaag gaaatgggcg
    12061 gggagggcct tcgtgcgtcg ccgcgccgcc gtccccttct ccctctccag cctcggggct
    12121 gtccgcgggg ggacggctgc cttcgggggg gacggggcag ggcggggttc ggcttctggc
    12181 gtgtgaccgg cggctctaga gcctctgcta accatgttca tgccttcttc tttttcctac
    12241 agctcctggg caacgtgctg gttattgtgc tgtctcatca ttttggcaaa gaattgatta
    12301 attcgagcga aggcgcgccc attactcgca tccattctca ggctgtctcg tctcgtctcg
    12361 cacgcgtgcc gccaccatgg agaagaagat gagcggatct cgtcccacac agtccagcga
    12421 gggatctcgt agatctcgtc actccgctcg tatcatcgct cagaccaccg tggacgccaa
    12481 actgcacgcc gatttcgagg agagcggctc ctcctttgat tactccacca gcgtgagggt
    12541 gactggtccc gtggtcgaga accagcctcc taggagcgac aaggtcacca caacctacct
    12601 ccatcatatc cagaagggca agctgatcca gccctttgga tgtttactgg ctttagacga
    12661 aaagaccttc aaggtcatcg cctactccga gaacgcctcc gaactgctca caatggcttc
    12721 ccacgccgtg cctagcgtgg gagagcaccc cgttctgggc atcggcaccg atatcagatc
    12781 tttatttacc gctcccagcg cttccgcttt acagaaggct ctcggcttcg gcgacgtgtc
    12841 tttactgaac cctatcctcg tccattgtcg tacatccgcc aagcccttct acgccattat
    12901 ccatagggtg accggatcca tcatcatcga cttcgaaccc gttaagccct atgaagtgcc
    12961 catgacagcc gccggagctt tacagagcta taagctggcc gccaaggcca tcaccagact
    13021 ccagtcttta cccagcggaa gcatggagag gctgtgcgac accatggtgc aagaagtctt
    13081 cgagctgact ggttacgatc gtgtcatggc ctacaagttc cacgaggacg accacggcga
    13141 ggtggtgagc gaagtgacca agcccggttt agaaccctat ttaggtttac actatcccgc
    13201 cacagacatc ccccaagctg ccagattttt atttatgaag aacaaggtga gaatgatcgt
    13261 ggactgcaac gccaagcacg ctagggtttt acaagatgag aagctgagct tcgatttaac
    13321 cctctgcggc agcactttaa gagctcccca ctcttgtcat ctgcaataca tggccaatat
    13381 ggacagcatc gcttctttag tgatggccgt ggtggtgaat gaggaggatg gagagggcga
    13441 tgctcccgat gccaccacac agcctcagaa gagaaagagg ctgtggggtt tagtggtctg
    13501 ccacaacacc acccccagat ttgtcccttt tcccttacgt tatgcttgtg aatttttagc
    13561 ccaagtgttt gccatccacg tcaacaagga ggtcgagctg gacaaccaga tggtggagaa
    13621 gaacatttta cgtacccaga cactcctctg cgacatgctc atgagggacg ctcccctcgg
    13681 catcgtgagc cagtccccca atattatgga tttagtcaag tgcgacggcg ccgccttatt
    13741 atacaaggac aagatctgga agctgggcac cacccctagc gagttccatt tacaagaaat
    13801 cgcttcttgg ctgtgtgagt accacatgga ttccaccggt ttaagcaccg attctttaca
    13861 cgacgctggc tttcctaggg ctttatcttt aggcgacagc gtctgcggaa tggctgccgt
    13921 tcgtatcagc agcaaagata tgattttctg gtttcgttcc cataccgccg gcgaagtgag
    13981 atggggcggc gccaaacacg accccgatga tagggacgat gccagaagga tgcaccccag
    14041 atcctccttc aaggcttttc tggaggtggt gaagaccaga agcttacctt ggaaggacta
    14101 cgaaatggat gccatccact ctttacagct catcttacgt aacgccttta aggacagcga
    14161 gaccaccgac gtgaacacaa aggtgatcta tagcaagctc aacgatctca agattgatgg
    14221 aatccaatcc ggagggtctg gctccggatc aagtggtggc agcggtaccg tggctgatga
    14281 ccccaacaac tacctgttct gccgggtcag aaagaatggt gtggctgccc cttctgccac
    14341 ctcccaactg tccacccggg ccctggaagg gatctttgag gccacccacc gcctgatcta
    14401 tggtgccaag gatgactctg ggcagagata cctggcctgg tctggccact ctgccagagt
    14461 gggtgctgcc agggacatgg ccagggctgg tgtgtccatc cctgaaatca tgcaggctgg
    14521 tggctggacc aatgtgaaca ttgtgatgaa ctacatcaga aacctggact ctgagactgg
    14581 ggccatggtg aggctgctcg aggatgggga ccccaagaaa aagcggaagg tgtgagaatt
    14641 cctgtgcctt ctagttgcca gccatctgtt gtttgcccct cccccgtgcc ttccttgacc
    14701 ctggaaggtg ccactcccac tgtcctttcc taataaaatg aggaaattgc atcgcattgt
    14761 ctgagtaggt gtcattctat tctggggggt ggggtggggc aggacagcaa gggggaggat
    14821 tgggaagaca atagcaggca tgctggggat gcggtgggct ctatggcttc tgaggcggaa
    14881 agaaccagct ggggctctag ggggtatccc cacgcgccct gtagcgtgta ccgctgggag
    14941 ttcgtagacg gaaacaaacg cagaatccaa gcgcggccgc ccaggataca t
//
