LOCUS       sequence-46536-e         865 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 865)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 865)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-BRD3
FEATURES             Location/Qualifiers
     source          1..865
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    18..117
                     /gene="mutant version of attL"
                     /label=attL2
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 acctggatcg ctggatggca ataatgattt tattttgact gatagtgacc tgttcgttgc
       61 aacaaattga taagcaatgc tttcttataa tgccaacttt gtacaagaaa gttggcaaaa
      121 ctccacaggt caagaaatga tctctgccgg ccgtggtcgt gctgttggcc ttcttggcag
      181 gagccttctt ctgctgagcc tgcttggcag gcggagccac cttggccttc ttctcttcct
      241 cggccttcac tttgtgcttc tccttctcct tctccttgtc cttcttcttc ttctccttct
      301 ccttcttctc cttcttcttc tttggtttgt ttactggggc ctgagacagg gcggccagct
      361 gctcgtgcac ggccttcagc tgctcctgca gctccgccag cctggtggcc cgctcctcct
      421 ccgagtccga gctgcctgag tccgaagagc tctcctcact gctacggctg ctctcagcgc
      481 ccttgctcac catgggggcc gcaggggcag gcagcgccgg tgcctccacg ggctcatctg
      541 gcatcttggc aaacctcatc tcaaacacgt cctggagctt ccgggccatg gccacaacct
      601 cgtggtctgg gggattgtat ttgtagcaat tcgagaacat cagccggaca tcagcagcaa
      661 agccctgtgc gtctgggtac tctcggccat ccatcttcct tttcacggtg ctgaggtcca
      721 tcgggtgctt gatgatgtcg tggtagtcgt gcagctccag gccctcggca tccactggct
      781 tgtagaaggc caggcgtagc cgcgtgcttc ttggatagca tctccctgag gatgctgtcg
      841 cagtagcgca ggtgctccga cagct
//
